LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania infantum
UniProt:
A4I6X3_LEIIN
TriTrypDb:
Length:
70

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I6X3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6X3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 32 34 PF00082 0.610
CLV_PCSK_KEX2_1 42 44 PF00082 0.453
CLV_PCSK_KEX2_1 5 7 PF00082 0.597
CLV_PCSK_PC1ET2_1 32 34 PF00082 0.560
CLV_PCSK_PC1ET2_1 42 44 PF00082 0.503
CLV_PCSK_PC1ET2_1 5 7 PF00082 0.597
DEG_MDM2_SWIB_1 37 44 PF02201 0.505
DEG_Nend_UBRbox_2 1 3 PF02207 0.541
LIG_14-3-3_CanoR_1 54 59 PF00244 0.501
LIG_Actin_WH2_2 40 56 PF00022 0.400
LIG_BRCT_BRCA1_1 33 37 PF00533 0.511
LIG_FHA_2 15 21 PF00498 0.584
LIG_Pex14_2 37 41 PF04695 0.585
MOD_CK2_1 14 20 PF00069 0.584
MOD_GlcNHglycan 66 69 PF01048 0.552
MOD_GSK3_1 54 61 PF00069 0.502
MOD_LATS_1 52 58 PF00433 0.506
MOD_NEK2_1 12 17 PF00069 0.490
MOD_PIKK_1 14 20 PF00454 0.494
MOD_SUMO_rev_2 28 34 PF00179 0.474
TRG_Pf-PMV_PEXEL_1 42 46 PF00026 0.497

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IEY9 Leishmania donovani 96% 100%
E9B1Z7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 72% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS