Putative transcription like protein nupm1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

transcription like protein nupm1 - putative

Species:

Leishmania infantum

UniProt:

A4I6W9_LEIIN

TriTrypDb:

LINF_310027200

Length:

478

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

A4I6W9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6W9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	186	190	PF00656	0.664
CLV_NRD_NRD_1	104	106	PF00675	0.471
CLV_NRD_NRD_1	111	113	PF00675	0.474
CLV_NRD_NRD_1	234	236	PF00675	0.480
CLV_NRD_NRD_1	284	286	PF00675	0.538
CLV_NRD_NRD_1	410	412	PF00675	0.563
CLV_NRD_NRD_1	48	50	PF00675	0.554
CLV_NRD_NRD_1	51	53	PF00675	0.538
CLV_PCSK_FUR_1	231	235	PF00082	0.481
CLV_PCSK_FUR_1	411	415	PF00082	0.528
CLV_PCSK_FUR_1	49	53	PF00082	0.496
CLV_PCSK_KEX2_1	103	105	PF00082	0.472
CLV_PCSK_KEX2_1	111	113	PF00082	0.469
CLV_PCSK_KEX2_1	233	235	PF00082	0.483
CLV_PCSK_KEX2_1	283	285	PF00082	0.542
CLV_PCSK_KEX2_1	410	412	PF00082	0.568
CLV_PCSK_KEX2_1	413	415	PF00082	0.559
CLV_PCSK_KEX2_1	48	50	PF00082	0.550
CLV_PCSK_KEX2_1	51	53	PF00082	0.534
CLV_PCSK_PC1ET2_1	103	105	PF00082	0.472
CLV_PCSK_PC1ET2_1	413	415	PF00082	0.535
CLV_PCSK_PC7_1	229	235	PF00082	0.462
CLV_Separin_Metazoa	92	96	PF03568	0.678
DEG_Kelch_Keap1_1	62	67	PF01344	0.832
DEG_SCF_FBW7_2	85	92	PF00400	0.649
DEG_SPOP_SBC_1	159	163	PF00917	0.758
DEG_SPOP_SBC_1	265	269	PF00917	0.677
DOC_CKS1_1	429	434	PF01111	0.688
DOC_PP2B_LxvP_1	173	176	PF13499	0.726
DOC_PP2B_LxvP_1	36	39	PF13499	0.676
DOC_PP2B_LxvP_1	458	461	PF13499	0.732
DOC_PP4_FxxP_1	429	432	PF00568	0.733
DOC_USP7_MATH_1	141	145	PF00917	0.833
DOC_USP7_MATH_1	289	293	PF00917	0.849
DOC_USP7_MATH_1	300	304	PF00917	0.724
DOC_USP7_MATH_1	355	359	PF00917	0.841
DOC_USP7_MATH_1	443	447	PF00917	0.791
DOC_USP7_MATH_1	464	468	PF00917	0.698
DOC_USP7_MATH_1	79	83	PF00917	0.714
DOC_USP7_UBL2_3	413	417	PF12436	0.752
DOC_USP7_UBL2_3	97	101	PF12436	0.642
DOC_WW_Pin1_4	344	349	PF00397	0.727
DOC_WW_Pin1_4	361	366	PF00397	0.691
DOC_WW_Pin1_4	376	381	PF00397	0.723
DOC_WW_Pin1_4	428	433	PF00397	0.698
DOC_WW_Pin1_4	53	58	PF00397	0.707
DOC_WW_Pin1_4	85	90	PF00397	0.652
LIG_14-3-3_CanoR_1	149	159	PF00244	0.758
LIG_14-3-3_CanoR_1	160	166	PF00244	0.771
LIG_14-3-3_CanoR_1	169	173	PF00244	0.629
LIG_14-3-3_CanoR_1	209	217	PF00244	0.716
LIG_14-3-3_CanoR_1	302	307	PF00244	0.776
LIG_14-3-3_CanoR_1	411	417	PF00244	0.734
LIG_BRCT_BRCA1_1	176	180	PF00533	0.669
LIG_BRCT_BRCA1_1	323	327	PF00533	0.746
LIG_BRCT_BRCA1_1	425	429	PF00533	0.738
LIG_Clathr_ClatBox_1	328	332	PF01394	0.738
LIG_FHA_1	160	166	PF00498	0.755
LIG_FHA_2	318	324	PF00498	0.721
LIG_FHA_2	413	419	PF00498	0.677
LIG_LIR_Apic_2	170	175	PF02991	0.822
LIG_LIR_Apic_2	426	432	PF02991	0.726
LIG_LIR_Nem_3	323	328	PF02991	0.819
LIG_LIR_Nem_3	415	419	PF02991	0.675
LIG_LIR_Nem_3	72	78	PF02991	0.779
LIG_LYPXL_yS_3	325	328	PF13949	0.821
LIG_MLH1_MIPbox_1	425	429	PF16413	0.738
LIG_MYND_1	85	89	PF01753	0.691
LIG_PCNA_yPIPBox_3	417	429	PF02747	0.727
LIG_Pex14_2	21	25	PF04695	0.405
LIG_SH2_GRB2like	370	373	PF00017	0.690
LIG_SH2_STAP1	249	253	PF00017	0.660
LIG_SH2_STAT5	172	175	PF00017	0.753
LIG_SH2_STAT5	223	226	PF00017	0.614
LIG_SH2_STAT5	32	35	PF00017	0.658
LIG_SH3_3	458	464	PF00018	0.730
LIG_SH3_3	468	474	PF00018	0.723
LIG_Sin3_3	7	14	PF02671	0.285
LIG_TRAF2_1	107	110	PF00917	0.676
LIG_TRAF2_1	89	92	PF00917	0.684
LIG_WW_3	83	87	PF00397	0.635
MOD_CK1_1	144	150	PF00069	0.715
MOD_CK1_1	154	160	PF00069	0.719
MOD_CK1_1	195	201	PF00069	0.721
MOD_CK1_1	204	210	PF00069	0.720
MOD_CK1_1	213	219	PF00069	0.694
MOD_CK1_1	256	262	PF00069	0.689
MOD_CK1_1	264	270	PF00069	0.717
MOD_CK1_1	305	311	PF00069	0.717
MOD_CK1_1	354	360	PF00069	0.682
MOD_CK1_1	371	377	PF00069	0.771
MOD_CK1_1	439	445	PF00069	0.712
MOD_CK1_1	62	68	PF00069	0.667
MOD_CK2_1	133	139	PF00069	0.785
MOD_CK2_1	251	257	PF00069	0.597
MOD_CK2_1	317	323	PF00069	0.653
MOD_CK2_1	331	337	PF00069	0.522
MOD_CK2_1	61	67	PF00069	0.810
MOD_GlcNHglycan	14	17	PF01048	0.439
MOD_GlcNHglycan	153	156	PF01048	0.652
MOD_GlcNHglycan	176	179	PF01048	0.701
MOD_GlcNHglycan	197	200	PF01048	0.753
MOD_GlcNHglycan	206	209	PF01048	0.691
MOD_GlcNHglycan	274	278	PF01048	0.711
MOD_GlcNHglycan	3	6	PF01048	0.538
MOD_GlcNHglycan	302	305	PF01048	0.750
MOD_GlcNHglycan	308	311	PF01048	0.693
MOD_GlcNHglycan	353	356	PF01048	0.711
MOD_GlcNHglycan	383	386	PF01048	0.705
MOD_GlcNHglycan	395	398	PF01048	0.664
MOD_GlcNHglycan	425	428	PF01048	0.616
MOD_GlcNHglycan	458	461	PF01048	0.706
MOD_GlcNHglycan	64	67	PF01048	0.668
MOD_GSK3_1	141	148	PF00069	0.665
MOD_GSK3_1	150	157	PF00069	0.640
MOD_GSK3_1	200	207	PF00069	0.753
MOD_GSK3_1	252	259	PF00069	0.649
MOD_GSK3_1	261	268	PF00069	0.715
MOD_GSK3_1	285	292	PF00069	0.706
MOD_GSK3_1	302	309	PF00069	0.733
MOD_GSK3_1	317	324	PF00069	0.701
MOD_GSK3_1	340	347	PF00069	0.760
MOD_GSK3_1	351	358	PF00069	0.698
MOD_GSK3_1	368	375	PF00069	0.543
MOD_GSK3_1	393	400	PF00069	0.657
MOD_GSK3_1	439	446	PF00069	0.697
MOD_N-GLC_1	355	360	PF02516	0.688
MOD_N-GLC_1	371	376	PF02516	0.551
MOD_NEK2_1	1	6	PF00069	0.574
MOD_NEK2_1	258	263	PF00069	0.780
MOD_NEK2_1	368	373	PF00069	0.609
MOD_NEK2_1	465	470	PF00069	0.609
MOD_NEK2_1	60	65	PF00069	0.813
MOD_NEK2_2	155	160	PF00069	0.670
MOD_PIKK_1	110	116	PF00454	0.601
MOD_PIKK_1	210	216	PF00454	0.678
MOD_PIKK_1	266	272	PF00454	0.823
MOD_PIKK_1	340	346	PF00454	0.696
MOD_PK_1	302	308	PF00069	0.733
MOD_PKA_1	283	289	PF00069	0.689
MOD_PKA_2	110	116	PF00069	0.601
MOD_PKA_2	148	154	PF00069	0.710
MOD_PKA_2	159	165	PF00069	0.726
MOD_PKA_2	168	174	PF00069	0.525
MOD_PKA_2	192	198	PF00069	0.771
MOD_PKA_2	201	207	PF00069	0.666
MOD_PKA_2	210	216	PF00069	0.500
MOD_PKA_2	283	289	PF00069	0.689
MOD_PKB_1	283	291	PF00069	0.774
MOD_Plk_1	465	471	PF00069	0.662
MOD_Plk_4	168	174	PF00069	0.760
MOD_Plk_4	219	225	PF00069	0.521
MOD_ProDKin_1	344	350	PF00069	0.660
MOD_ProDKin_1	361	367	PF00069	0.613
MOD_ProDKin_1	376	382	PF00069	0.659
MOD_ProDKin_1	428	434	PF00069	0.623
MOD_ProDKin_1	53	59	PF00069	0.638
MOD_ProDKin_1	85	91	PF00069	0.556
TRG_DiLeu_BaEn_2	322	328	PF01217	0.653
TRG_DiLeu_BaEn_4	236	242	PF01217	0.577
TRG_ENDOCYTIC_2	249	252	PF00928	0.566
TRG_ENDOCYTIC_2	325	328	PF00928	0.693
TRG_ER_diArg_1	224	227	PF00400	0.592
TRG_ER_diArg_1	229	232	PF00400	0.595
TRG_ER_diArg_1	233	235	PF00400	0.602
TRG_ER_diArg_1	283	285	PF00400	0.769
TRG_ER_diArg_1	409	411	PF00400	0.712
TRG_ER_diArg_1	48	50	PF00400	0.687
TRG_NLS_MonoExtN_4	101	107	PF00514	0.583
TRG_Pf-PMV_PEXEL_1	312	316	PF00026	0.704

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IGX0	Leptomonas seymouri	47%	98%
A0A3Q8IGF6	Leishmania donovani	98%	100%
A4HJH6	Leishmania braziliensis	62%	97%
A4HJX3	Leishmania braziliensis	61%	97%
E9B1Z3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4Q668	Leishmania major	89%	100%