Triplex capsid protein 1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I6T0_LEIIN

TriTrypDb:

LINF_310022500

Length:

945

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I6T0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6T0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	431	435	PF00656	0.596
CLV_C14_Caspase3-7	544	548	PF00656	0.682
CLV_NRD_NRD_1	174	176	PF00675	0.567
CLV_NRD_NRD_1	447	449	PF00675	0.358
CLV_NRD_NRD_1	613	615	PF00675	0.438
CLV_NRD_NRD_1	635	637	PF00675	0.690
CLV_PCSK_KEX2_1	174	176	PF00082	0.534
CLV_PCSK_KEX2_1	447	449	PF00082	0.358
CLV_PCSK_KEX2_1	613	615	PF00082	0.496
CLV_PCSK_SKI1_1	115	119	PF00082	0.382
CLV_PCSK_SKI1_1	196	200	PF00082	0.397
CLV_PCSK_SKI1_1	295	299	PF00082	0.500
CLV_PCSK_SKI1_1	376	380	PF00082	0.424
CLV_PCSK_SKI1_1	583	587	PF00082	0.503
CLV_PCSK_SKI1_1	85	89	PF00082	0.434
DEG_APCC_DBOX_1	114	122	PF00400	0.380
DEG_COP1_1	3	13	PF00400	0.406
DEG_SCF_FBW7_1	414	421	PF00400	0.458
DOC_CDC14_PxL_1	215	223	PF14671	0.426
DOC_CKS1_1	35	40	PF01111	0.434
DOC_CYCLIN_RxL_1	80	91	PF00134	0.430
DOC_MAPK_DCC_7	229	237	PF00069	0.376
DOC_MAPK_DCC_7	710	718	PF00069	0.555
DOC_MAPK_gen_1	174	181	PF00069	0.410
DOC_MAPK_gen_1	447	454	PF00069	0.367
DOC_MAPK_MEF2A_6	165	173	PF00069	0.497
DOC_MAPK_MEF2A_6	229	237	PF00069	0.407
DOC_MAPK_MEF2A_6	710	718	PF00069	0.701
DOC_PP2B_LxvP_1	249	252	PF13499	0.490
DOC_PP4_FxxP_1	15	18	PF00568	0.472
DOC_PP4_FxxP_1	35	38	PF00568	0.454
DOC_PP4_FxxP_1	454	457	PF00568	0.498
DOC_PP4_FxxP_1	627	630	PF00568	0.641
DOC_PP4_FxxP_1	698	701	PF00568	0.606
DOC_PP4_MxPP_1	684	687	PF00568	0.560
DOC_USP7_MATH_1	132	136	PF00917	0.499
DOC_USP7_MATH_1	139	143	PF00917	0.387
DOC_USP7_MATH_1	252	256	PF00917	0.517
DOC_USP7_MATH_1	355	359	PF00917	0.597
DOC_USP7_MATH_1	377	381	PF00917	0.431
DOC_USP7_MATH_1	465	469	PF00917	0.710
DOC_USP7_MATH_1	537	541	PF00917	0.741
DOC_USP7_MATH_1	597	601	PF00917	0.432
DOC_USP7_MATH_1	701	705	PF00917	0.678
DOC_USP7_MATH_1	855	859	PF00917	0.633
DOC_USP7_MATH_1	887	891	PF00917	0.678
DOC_USP7_UBL2_3	706	710	PF12436	0.664
DOC_WW_Pin1_4	137	142	PF00397	0.674
DOC_WW_Pin1_4	34	39	PF00397	0.403
DOC_WW_Pin1_4	414	419	PF00397	0.575
DOC_WW_Pin1_4	463	468	PF00397	0.697
DOC_WW_Pin1_4	498	503	PF00397	0.514
DOC_WW_Pin1_4	535	540	PF00397	0.662
DOC_WW_Pin1_4	679	684	PF00397	0.771
DOC_WW_Pin1_4	719	724	PF00397	0.717
DOC_WW_Pin1_4	806	811	PF00397	0.706
DOC_WW_Pin1_4	832	837	PF00397	0.627
DOC_WW_Pin1_4	889	894	PF00397	0.738
DOC_WW_Pin1_4	926	931	PF00397	0.692
LIG_14-3-3_CanoR_1	143	153	PF00244	0.447
LIG_14-3-3_CanoR_1	376	384	PF00244	0.521
LIG_14-3-3_CanoR_1	405	409	PF00244	0.558
LIG_14-3-3_CanoR_1	89	97	PF00244	0.535
LIG_BIR_III_2	549	553	PF00653	0.508
LIG_BRCT_BRCA1_1	253	257	PF00533	0.420
LIG_EVH1_1	739	743	PF00568	0.684
LIG_FHA_1	126	132	PF00498	0.450
LIG_FHA_1	157	163	PF00498	0.405
LIG_FHA_1	210	216	PF00498	0.317
LIG_FHA_1	365	371	PF00498	0.458
LIG_FHA_1	373	379	PF00498	0.470
LIG_FHA_1	397	403	PF00498	0.445
LIG_FHA_1	415	421	PF00498	0.468
LIG_FHA_1	435	441	PF00498	0.601
LIG_FHA_1	485	491	PF00498	0.676
LIG_FHA_1	498	504	PF00498	0.627
LIG_FHA_1	861	867	PF00498	0.554
LIG_FHA_1	890	896	PF00498	0.624
LIG_FHA_2	399	405	PF00498	0.472
LIG_FHA_2	542	548	PF00498	0.681
LIG_FHA_2	584	590	PF00498	0.508
LIG_Integrin_RGD_1	448	450	PF01839	0.393
LIG_LIR_Apic_2	12	18	PF02991	0.487
LIG_LIR_Apic_2	32	38	PF02991	0.429
LIG_LIR_Apic_2	453	458	PF02991	0.501
LIG_LIR_Apic_2	48	53	PF02991	0.425
LIG_LIR_Gen_1	147	156	PF02991	0.417
LIG_LIR_Gen_1	224	233	PF02991	0.411
LIG_LIR_Gen_1	333	339	PF02991	0.542
LIG_LIR_Gen_1	905	913	PF02991	0.567
LIG_LIR_Nem_3	147	152	PF02991	0.429
LIG_LIR_Nem_3	224	228	PF02991	0.399
LIG_LIR_Nem_3	333	338	PF02991	0.540
LIG_LIR_Nem_3	618	624	PF02991	0.460
LIG_LIR_Nem_3	771	776	PF02991	0.656
LIG_LIR_Nem_3	797	801	PF02991	0.631
LIG_LIR_Nem_3	902	906	PF02991	0.583
LIG_MYND_1	683	687	PF01753	0.652
LIG_MYND_1	830	834	PF01753	0.611
LIG_PCNA_PIPBox_1	277	286	PF02747	0.368
LIG_PCNA_yPIPBox_3	99	113	PF02747	0.442
LIG_SH2_CRK	58	62	PF00017	0.501
LIG_SH2_CRK	621	625	PF00017	0.380
LIG_SH2_NCK_1	335	339	PF00017	0.572
LIG_SH2_NCK_1	50	54	PF00017	0.419
LIG_SH2_NCK_1	594	598	PF00017	0.492
LIG_SH2_PTP2	455	458	PF00017	0.489
LIG_SH2_PTP2	906	909	PF00017	0.541
LIG_SH2_SRC	455	458	PF00017	0.528
LIG_SH2_SRC	594	597	PF00017	0.494
LIG_SH2_STAP1	335	339	PF00017	0.546
LIG_SH2_STAT3	205	208	PF00017	0.429
LIG_SH2_STAT5	130	133	PF00017	0.453
LIG_SH2_STAT5	203	206	PF00017	0.419
LIG_SH2_STAT5	258	261	PF00017	0.431
LIG_SH2_STAT5	262	265	PF00017	0.419
LIG_SH2_STAT5	272	275	PF00017	0.465
LIG_SH2_STAT5	284	287	PF00017	0.402
LIG_SH2_STAT5	335	338	PF00017	0.567
LIG_SH2_STAT5	34	37	PF00017	0.526
LIG_SH2_STAT5	368	371	PF00017	0.459
LIG_SH2_STAT5	373	376	PF00017	0.438
LIG_SH2_STAT5	392	395	PF00017	0.320
LIG_SH2_STAT5	455	458	PF00017	0.528
LIG_SH2_STAT5	50	53	PF00017	0.271
LIG_SH2_STAT5	608	611	PF00017	0.387
LIG_SH2_STAT5	729	732	PF00017	0.623
LIG_SH2_STAT5	796	799	PF00017	0.671
LIG_SH2_STAT5	891	894	PF00017	0.682
LIG_SH2_STAT5	906	909	PF00017	0.541
LIG_SH3_2	11	16	PF14604	0.450
LIG_SH3_2	169	174	PF14604	0.433
LIG_SH3_3	133	139	PF00018	0.463
LIG_SH3_3	160	166	PF00018	0.488
LIG_SH3_3	213	219	PF00018	0.353
LIG_SH3_3	35	41	PF00018	0.486
LIG_SH3_3	680	686	PF00018	0.742
LIG_SH3_3	734	740	PF00018	0.663
LIG_SH3_3	8	14	PF00018	0.413
LIG_SH3_3	827	833	PF00018	0.708
LIG_SUMO_SIM_anti_2	195	201	PF11976	0.381
LIG_SUMO_SIM_anti_2	397	404	PF11976	0.425
LIG_SUMO_SIM_par_1	397	404	PF11976	0.454
LIG_SUMO_SIM_par_1	714	719	PF11976	0.756
LIG_SxIP_EBH_1	225	239	PF03271	0.343
LIG_WRC_WIRS_1	284	289	PF05994	0.408
LIG_WRC_WIRS_1	451	456	PF05994	0.500
LIG_WRC_WIRS_1	795	800	PF05994	0.667
LIG_WRC_WIRS_1	940	945	PF05994	0.537
LIG_WW_1	742	745	PF00397	0.690
LIG_WW_2	830	833	PF00397	0.699
MOD_CDC14_SPxK_1	140	143	PF00782	0.548
MOD_CDK_SPxK_1	137	143	PF00069	0.518
MOD_CK1_1	333	339	PF00069	0.663
MOD_CK1_1	382	388	PF00069	0.438
MOD_CK1_1	398	404	PF00069	0.501
MOD_CK1_1	459	465	PF00069	0.656
MOD_CK1_1	497	503	PF00069	0.642
MOD_CK1_1	505	511	PF00069	0.672
MOD_CK1_1	541	547	PF00069	0.766
MOD_CK1_1	699	705	PF00069	0.579
MOD_CK1_1	719	725	PF00069	0.573
MOD_CK1_1	732	738	PF00069	0.540
MOD_CK1_1	748	754	PF00069	0.727
MOD_CK1_1	806	812	PF00069	0.765
MOD_CK1_1	860	866	PF00069	0.629
MOD_CK1_1	902	908	PF00069	0.552
MOD_CK2_1	475	481	PF00069	0.609
MOD_CK2_1	485	491	PF00069	0.571
MOD_GlcNHglycan	146	149	PF01048	0.460
MOD_GlcNHglycan	187	190	PF01048	0.491
MOD_GlcNHglycan	19	22	PF01048	0.461
MOD_GlcNHglycan	357	360	PF01048	0.631
MOD_GlcNHglycan	437	440	PF01048	0.494
MOD_GlcNHglycan	5	8	PF01048	0.388
MOD_GlcNHglycan	507	510	PF01048	0.612
MOD_GlcNHglycan	515	518	PF01048	0.642
MOD_GlcNHglycan	529	534	PF01048	0.715
MOD_GlcNHglycan	540	543	PF01048	0.591
MOD_GlcNHglycan	642	645	PF01048	0.671
MOD_GlcNHglycan	66	69	PF01048	0.561
MOD_GlcNHglycan	666	669	PF01048	0.691
MOD_GlcNHglycan	718	721	PF01048	0.667
MOD_GlcNHglycan	734	737	PF01048	0.562
MOD_GlcNHglycan	750	753	PF01048	0.682
MOD_GlcNHglycan	880	883	PF01048	0.599
MOD_GlcNHglycan	921	924	PF01048	0.615
MOD_GSK3_1	223	230	PF00069	0.380
MOD_GSK3_1	326	333	PF00069	0.647
MOD_GSK3_1	355	362	PF00069	0.605
MOD_GSK3_1	372	379	PF00069	0.489
MOD_GSK3_1	412	419	PF00069	0.582
MOD_GSK3_1	456	463	PF00069	0.639
MOD_GSK3_1	465	472	PF00069	0.632
MOD_GSK3_1	494	501	PF00069	0.706
MOD_GSK3_1	525	532	PF00069	0.680
MOD_GSK3_1	537	544	PF00069	0.678
MOD_GSK3_1	566	573	PF00069	0.387
MOD_GSK3_1	64	71	PF00069	0.600
MOD_GSK3_1	768	775	PF00069	0.664
MOD_GSK3_1	799	806	PF00069	0.607
MOD_GSK3_1	851	858	PF00069	0.659
MOD_GSK3_1	887	894	PF00069	0.605
MOD_GSK3_1	915	922	PF00069	0.621
MOD_GSK3_1	926	933	PF00069	0.653
MOD_N-GLC_1	192	197	PF02516	0.422
MOD_N-GLC_1	382	387	PF02516	0.452
MOD_N-GLC_1	498	503	PF02516	0.644
MOD_NEK2_1	469	474	PF00069	0.805
MOD_NEK2_1	484	489	PF00069	0.704
MOD_NEK2_1	503	508	PF00069	0.524
MOD_NEK2_1	566	571	PF00069	0.452
MOD_NEK2_1	716	721	PF00069	0.576
MOD_NEK2_1	760	765	PF00069	0.648
MOD_NEK2_1	772	777	PF00069	0.470
MOD_NEK2_1	878	883	PF00069	0.602
MOD_NEK2_1	88	93	PF00069	0.398
MOD_NEK2_1	916	921	PF00069	0.614
MOD_NEK2_1	95	100	PF00069	0.349
MOD_NEK2_2	223	228	PF00069	0.381
MOD_NMyristoyl	1	7	PF02799	0.424
MOD_PIKK_1	696	702	PF00454	0.699
MOD_PIKK_1	746	752	PF00454	0.661
MOD_PIKK_1	799	805	PF00454	0.607
MOD_PIKK_1	855	861	PF00454	0.618
MOD_PKA_1	556	562	PF00069	0.451
MOD_PKA_2	404	410	PF00069	0.587
MOD_PKA_2	460	466	PF00069	0.695
MOD_PKA_2	631	637	PF00069	0.639
MOD_PKA_2	88	94	PF00069	0.535
MOD_Plk_1	192	198	PF00069	0.418
MOD_Plk_1	396	402	PF00069	0.498
MOD_Plk_1	68	74	PF00069	0.490
MOD_Plk_2-3	404	410	PF00069	0.552
MOD_Plk_4	158	164	PF00069	0.410
MOD_Plk_4	330	336	PF00069	0.562
MOD_Plk_4	398	404	PF00069	0.411
MOD_Plk_4	450	456	PF00069	0.461
MOD_Plk_4	566	572	PF00069	0.363
MOD_Plk_4	603	609	PF00069	0.470
MOD_Plk_4	768	774	PF00069	0.615
MOD_Plk_4	794	800	PF00069	0.665
MOD_Plk_4	902	908	PF00069	0.688
MOD_ProDKin_1	137	143	PF00069	0.686
MOD_ProDKin_1	34	40	PF00069	0.400
MOD_ProDKin_1	414	420	PF00069	0.580
MOD_ProDKin_1	463	469	PF00069	0.700
MOD_ProDKin_1	498	504	PF00069	0.515
MOD_ProDKin_1	535	541	PF00069	0.662
MOD_ProDKin_1	679	685	PF00069	0.772
MOD_ProDKin_1	719	725	PF00069	0.714
MOD_ProDKin_1	806	812	PF00069	0.705
MOD_ProDKin_1	832	838	PF00069	0.629
MOD_ProDKin_1	889	895	PF00069	0.739
MOD_ProDKin_1	926	932	PF00069	0.692
MOD_SUMO_for_1	290	293	PF00179	0.439
MOD_SUMO_rev_2	573	582	PF00179	0.384
TRG_DiLeu_BaLyEn_6	166	171	PF01217	0.465
TRG_DiLeu_BaLyEn_6	499	504	PF01217	0.495
TRG_DiLeu_BaLyEn_6	82	87	PF01217	0.435
TRG_ENDOCYTIC_2	284	287	PF00928	0.474
TRG_ENDOCYTIC_2	335	338	PF00928	0.528
TRG_ENDOCYTIC_2	621	624	PF00928	0.380
TRG_ENDOCYTIC_2	796	799	PF00928	0.671
TRG_ENDOCYTIC_2	906	909	PF00928	0.523
TRG_ER_diArg_1	112	115	PF00400	0.440
TRG_ER_diArg_1	173	175	PF00400	0.521
TRG_ER_diArg_1	446	448	PF00400	0.377
TRG_ER_diArg_1	612	614	PF00400	0.459
TRG_Pf-PMV_PEXEL_1	295	299	PF00026	0.500
TRG_Pf-PMV_PEXEL_1	44	48	PF00026	0.450

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBS8	Leptomonas seymouri	42%	100%
A0A3S7X4H0	Leishmania donovani	98%	100%
A0A422NZA5	Trypanosoma rangeli	31%	100%
A4HJD3	Leishmania braziliensis	70%	99%
E9B1V2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	99%
Q4Q6B0	Leishmania major	90%	100%