LeishMANIAdb
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Pentamidine resistance protein 1

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Pentamidine resistance protein 1
Gene product:
pentamidine resistance protein 1
Species:
Leishmania infantum
UniProt:
A4I6S0_LEIIN
TriTrypDb:
LINF_310021100
Length:
1806

Annotations

LeishMANIAdb annotations

Multidrug resistance transporters, involved in active transport of various unidentified small-molecule substrates.. ABC transporters belonging to subfamily C.

Annotations by Jardim et al.

Drug resistance proteins, Pentamidine resistance 1 ABC PRP1

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 21
NetGPI no yes: 0, no: 21
Cellular components
Term Name Level Count
GO:0016020 membrane 2 22
GO:0110165 cellular anatomical entity 1 22

Expansion

Sequence features

A4I6S0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6S0

Function

Biological processes
Term Name Level Count
GO:0006810 transport 3 4
GO:0009987 cellular process 1 4
GO:0051179 localization 1 4
GO:0051234 establishment of localization 2 4
GO:0055085 transmembrane transport 2 4
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 22
GO:0005215 transporter activity 1 22
GO:0005488 binding 1 22
GO:0005524 ATP binding 5 22
GO:0015399 primary active transmembrane transporter activity 4 22
GO:0017076 purine nucleotide binding 4 22
GO:0022804 active transmembrane transporter activity 3 22
GO:0022857 transmembrane transporter activity 2 22
GO:0030554 adenyl nucleotide binding 5 22
GO:0032553 ribonucleotide binding 3 22
GO:0032555 purine ribonucleotide binding 4 22
GO:0032559 adenyl ribonucleotide binding 5 22
GO:0035639 purine ribonucleoside triphosphate binding 4 22
GO:0036094 small molecule binding 2 22
GO:0042626 ATPase-coupled transmembrane transporter activity 2 22
GO:0043167 ion binding 2 22
GO:0043168 anion binding 3 22
GO:0097159 organic cyclic compound binding 2 22
GO:0097367 carbohydrate derivative binding 2 22
GO:0140359 ABC-type transporter activity 3 22
GO:0140657 ATP-dependent activity 1 22
GO:1901265 nucleoside phosphate binding 3 22
GO:1901363 heterocyclic compound binding 2 22
GO:0003824 catalytic activity 1 3
GO:0016787 hydrolase activity 2 3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1094 1098 PF00656 0.710
CLV_C14_Caspase3-7 1738 1742 PF00656 0.533
CLV_C14_Caspase3-7 901 905 PF00656 0.601
CLV_MEL_PAP_1 1225 1231 PF00089 0.266
CLV_NRD_NRD_1 1195 1197 PF00675 0.348
CLV_NRD_NRD_1 1295 1297 PF00675 0.279
CLV_NRD_NRD_1 1457 1459 PF00675 0.503
CLV_NRD_NRD_1 1572 1574 PF00675 0.357
CLV_NRD_NRD_1 1739 1741 PF00675 0.319
CLV_NRD_NRD_1 25 27 PF00675 0.454
CLV_NRD_NRD_1 325 327 PF00675 0.414
CLV_NRD_NRD_1 354 356 PF00675 0.304
CLV_NRD_NRD_1 470 472 PF00675 0.364
CLV_NRD_NRD_1 508 510 PF00675 0.293
CLV_NRD_NRD_1 647 649 PF00675 0.459
CLV_NRD_NRD_1 660 662 PF00675 0.412
CLV_NRD_NRD_1 669 671 PF00675 0.514
CLV_NRD_NRD_1 681 683 PF00675 0.396
CLV_NRD_NRD_1 793 795 PF00675 0.230
CLV_NRD_NRD_1 909 911 PF00675 0.425
CLV_PCSK_FUR_1 352 356 PF00082 0.292
CLV_PCSK_FUR_1 468 472 PF00082 0.251
CLV_PCSK_FUR_1 505 509 PF00082 0.231
CLV_PCSK_KEX2_1 1195 1197 PF00082 0.348
CLV_PCSK_KEX2_1 1294 1296 PF00082 0.279
CLV_PCSK_KEX2_1 1457 1459 PF00082 0.453
CLV_PCSK_KEX2_1 1572 1574 PF00082 0.302
CLV_PCSK_KEX2_1 1739 1741 PF00082 0.319
CLV_PCSK_KEX2_1 25 27 PF00082 0.450
CLV_PCSK_KEX2_1 354 356 PF00082 0.304
CLV_PCSK_KEX2_1 470 472 PF00082 0.284
CLV_PCSK_KEX2_1 507 509 PF00082 0.342
CLV_PCSK_KEX2_1 647 649 PF00082 0.482
CLV_PCSK_KEX2_1 659 661 PF00082 0.465
CLV_PCSK_KEX2_1 669 671 PF00082 0.545
CLV_PCSK_KEX2_1 793 795 PF00082 0.231
CLV_PCSK_KEX2_1 909 911 PF00082 0.427
CLV_PCSK_PC7_1 1291 1297 PF00082 0.292
CLV_PCSK_SKI1_1 1081 1085 PF00082 0.442
CLV_PCSK_SKI1_1 1346 1350 PF00082 0.299
CLV_PCSK_SKI1_1 1572 1576 PF00082 0.276
CLV_PCSK_SKI1_1 1605 1609 PF00082 0.291
CLV_PCSK_SKI1_1 1656 1660 PF00082 0.309
CLV_PCSK_SKI1_1 1663 1667 PF00082 0.361
CLV_PCSK_SKI1_1 1734 1738 PF00082 0.310
CLV_PCSK_SKI1_1 327 331 PF00082 0.424
CLV_PCSK_SKI1_1 371 375 PF00082 0.250
CLV_PCSK_SKI1_1 407 411 PF00082 0.478
CLV_PCSK_SKI1_1 480 484 PF00082 0.296
CLV_PCSK_SKI1_1 52 56 PF00082 0.504
CLV_PCSK_SKI1_1 68 72 PF00082 0.304
CLV_PCSK_SKI1_1 719 723 PF00082 0.366
CLV_PCSK_SKI1_1 745 749 PF00082 0.292
DEG_APCC_DBOX_1 1218 1226 PF00400 0.489
DEG_APCC_DBOX_1 1386 1394 PF00400 0.292
DEG_APCC_DBOX_1 1507 1515 PF00400 0.615
DEG_APCC_DBOX_1 1604 1612 PF00400 0.428
DEG_APCC_DBOX_1 284 292 PF00400 0.531
DEG_APCC_DBOX_1 67 75 PF00400 0.545
DEG_APCC_DBOX_1 718 726 PF00400 0.584
DEG_APCC_DBOX_1 730 738 PF00400 0.515
DOC_ANK_TNKS_1 1762 1769 PF00023 0.618
DOC_CDC14_PxL_1 270 278 PF14671 0.502
DOC_CKS1_1 303 308 PF01111 0.414
DOC_CKS1_1 522 527 PF01111 0.275
DOC_CYCLIN_RxL_1 1569 1576 PF00134 0.444
DOC_CYCLIN_RxL_1 1660 1670 PF00134 0.560
DOC_CYCLIN_RxL_1 1731 1741 PF00134 0.508
DOC_CYCLIN_RxL_1 22 32 PF00134 0.528
DOC_CYCLIN_RxL_1 322 333 PF00134 0.206
DOC_CYCLIN_RxL_1 49 57 PF00134 0.549
DOC_CYCLIN_yCln2_LP_2 340 346 PF00134 0.303
DOC_CYCLIN_yCln2_LP_2 896 902 PF00134 0.490
DOC_MAPK_gen_1 124 133 PF00069 0.573
DOC_MAPK_gen_1 1506 1515 PF00069 0.613
DOC_MAPK_gen_1 282 291 PF00069 0.629
DOC_MAPK_gen_1 326 332 PF00069 0.214
DOC_MAPK_gen_1 659 666 PF00069 0.586
DOC_MAPK_gen_1 682 689 PF00069 0.612
DOC_MAPK_gen_1 909 917 PF00069 0.533
DOC_MAPK_HePTP_8 1503 1515 PF00069 0.640
DOC_MAPK_MEF2A_6 1346 1354 PF00069 0.538
DOC_MAPK_MEF2A_6 1387 1395 PF00069 0.289
DOC_MAPK_MEF2A_6 1506 1515 PF00069 0.651
DOC_MAPK_MEF2A_6 1538 1545 PF00069 0.506
DOC_MAPK_MEF2A_6 1605 1613 PF00069 0.421
DOC_MAPK_MEF2A_6 361 369 PF00069 0.496
DOC_MAPK_MEF2A_6 659 666 PF00069 0.616
DOC_MAPK_MEF2A_6 72 80 PF00069 0.459
DOC_MAPK_MEF2A_6 731 738 PF00069 0.566
DOC_MAPK_NFAT4_5 1538 1546 PF00069 0.506
DOC_MAPK_RevD_3 634 648 PF00069 0.568
DOC_PIKK_1 496 504 PF02985 0.492
DOC_PP1_RVXF_1 1514 1521 PF00149 0.533
DOC_PP1_RVXF_1 167 173 PF00149 0.629
DOC_PP1_RVXF_1 179 185 PF00149 0.555
DOC_PP1_RVXF_1 325 332 PF00149 0.224
DOC_PP1_RVXF_1 405 411 PF00149 0.273
DOC_PP1_RVXF_1 724 730 PF00149 0.424
DOC_PP2B_PxIxI_1 549 555 PF00149 0.337
DOC_PP4_FxxP_1 522 525 PF00568 0.228
DOC_PP4_MxPP_1 91 94 PF00568 0.507
DOC_USP7_MATH_1 1073 1077 PF00917 0.768
DOC_USP7_MATH_1 1083 1087 PF00917 0.716
DOC_USP7_MATH_1 13 17 PF00917 0.664
DOC_USP7_MATH_1 1489 1493 PF00917 0.641
DOC_USP7_MATH_1 1607 1611 PF00917 0.491
DOC_USP7_MATH_1 1624 1628 PF00917 0.595
DOC_USP7_MATH_1 1633 1637 PF00917 0.540
DOC_USP7_MATH_1 1797 1801 PF00917 0.519
DOC_USP7_MATH_1 36 40 PF00917 0.670
DOC_USP7_MATH_1 392 396 PF00917 0.449
DOC_USP7_MATH_1 553 557 PF00917 0.251
DOC_USP7_MATH_1 568 572 PF00917 0.523
DOC_USP7_MATH_1 616 620 PF00917 0.640
DOC_USP7_MATH_1 740 744 PF00917 0.519
DOC_USP7_MATH_1 801 805 PF00917 0.429
DOC_USP7_MATH_1 845 849 PF00917 0.576
DOC_USP7_MATH_1 879 883 PF00917 0.502
DOC_USP7_MATH_1 973 977 PF00917 0.694
DOC_USP7_MATH_1 996 1000 PF00917 0.685
DOC_WW_Pin1_4 1035 1040 PF00397 0.738
DOC_WW_Pin1_4 1109 1114 PF00397 0.539
DOC_WW_Pin1_4 1217 1222 PF00397 0.490
DOC_WW_Pin1_4 1262 1267 PF00397 0.337
DOC_WW_Pin1_4 1299 1304 PF00397 0.490
DOC_WW_Pin1_4 1377 1382 PF00397 0.415
DOC_WW_Pin1_4 190 195 PF00397 0.677
DOC_WW_Pin1_4 302 307 PF00397 0.414
DOC_WW_Pin1_4 373 378 PF00397 0.452
DOC_WW_Pin1_4 521 526 PF00397 0.423
DOC_WW_Pin1_4 671 676 PF00397 0.726
DOC_WW_Pin1_4 810 815 PF00397 0.492
LIG_14-3-3_CanoR_1 1294 1300 PF00244 0.522
LIG_14-3-3_CanoR_1 1465 1472 PF00244 0.610
LIG_14-3-3_CanoR_1 1564 1569 PF00244 0.515
LIG_14-3-3_CanoR_1 1572 1578 PF00244 0.499
LIG_14-3-3_CanoR_1 1709 1714 PF00244 0.613
LIG_14-3-3_CanoR_1 1776 1785 PF00244 0.621
LIG_14-3-3_CanoR_1 189 197 PF00244 0.604
LIG_14-3-3_CanoR_1 243 251 PF00244 0.597
LIG_14-3-3_CanoR_1 282 292 PF00244 0.501
LIG_14-3-3_CanoR_1 31 36 PF00244 0.583
LIG_14-3-3_CanoR_1 354 360 PF00244 0.446
LIG_14-3-3_CanoR_1 361 366 PF00244 0.451
LIG_14-3-3_CanoR_1 627 633 PF00244 0.625
LIG_14-3-3_CanoR_1 726 730 PF00244 0.516
LIG_14-3-3_CanoR_1 731 737 PF00244 0.490
LIG_14-3-3_CanoR_1 880 884 PF00244 0.506
LIG_14-3-3_CanoR_1 925 935 PF00244 0.540
LIG_Actin_WH2_2 1654 1669 PF00022 0.565
LIG_Actin_WH2_2 709 725 PF00022 0.633
LIG_AP2alpha_2 1594 1596 PF02296 0.566
LIG_APCC_ABBA_1 1593 1598 PF00400 0.503
LIG_APCC_ABBA_1 934 939 PF00400 0.563
LIG_BIR_II_1 1 5 PF00653 0.725
LIG_BIR_III_4 1765 1769 PF00653 0.626
LIG_BRCT_BRCA1_1 107 111 PF00533 0.540
LIG_BRCT_BRCA1_1 1491 1495 PF00533 0.617
LIG_BRCT_BRCA1_1 1609 1613 PF00533 0.488
LIG_BRCT_BRCA1_1 1619 1623 PF00533 0.488
LIG_BRCT_BRCA1_1 356 360 PF00533 0.504
LIG_BRCT_BRCA1_1 545 549 PF00533 0.221
LIG_Clathr_ClatBox_1 1332 1336 PF01394 0.431
LIG_EH1_1 331 339 PF00400 0.204
LIG_eIF4E_1 1277 1283 PF01652 0.282
LIG_FHA_1 1249 1255 PF00498 0.320
LIG_FHA_1 1347 1353 PF00498 0.527
LIG_FHA_1 1394 1400 PF00498 0.319
LIG_FHA_1 1538 1544 PF00498 0.568
LIG_FHA_1 1563 1569 PF00498 0.428
LIG_FHA_1 1677 1683 PF00498 0.525
LIG_FHA_1 257 263 PF00498 0.574
LIG_FHA_1 303 309 PF00498 0.399
LIG_FHA_1 360 366 PF00498 0.475
LIG_FHA_1 385 391 PF00498 0.532
LIG_FHA_1 417 423 PF00498 0.414
LIG_FHA_1 470 476 PF00498 0.459
LIG_FHA_1 524 530 PF00498 0.387
LIG_FHA_1 533 539 PF00498 0.346
LIG_FHA_1 557 563 PF00498 0.317
LIG_FHA_1 577 583 PF00498 0.530
LIG_FHA_1 733 739 PF00498 0.508
LIG_FHA_1 922 928 PF00498 0.536
LIG_FHA_2 1007 1013 PF00498 0.724
LIG_FHA_2 1089 1095 PF00498 0.735
LIG_FHA_2 1101 1107 PF00498 0.611
LIG_FHA_2 1213 1219 PF00498 0.604
LIG_FHA_2 1340 1346 PF00498 0.472
LIG_FHA_2 1598 1604 PF00498 0.474
LIG_FHA_2 785 791 PF00498 0.492
LIG_FHA_2 984 990 PF00498 0.708
LIG_HP1_1 76 80 PF01393 0.484
LIG_IBAR_NPY_1 75 77 PF08397 0.546
LIG_Integrin_isoDGR_2 153 155 PF01839 0.387
LIG_Integrin_isoDGR_2 703 705 PF01839 0.400
LIG_IRF3_LxIS_1 369 376 PF10401 0.414
LIG_LIR_Apic_2 1261 1266 PF02991 0.404
LIG_LIR_Apic_2 1565 1569 PF02991 0.488
LIG_LIR_Apic_2 87 93 PF02991 0.636
LIG_LIR_Gen_1 1147 1158 PF02991 0.274
LIG_LIR_Gen_1 1349 1359 PF02991 0.493
LIG_LIR_Gen_1 1670 1680 PF02991 0.526
LIG_LIR_Gen_1 275 284 PF02991 0.623
LIG_LIR_Gen_1 47 55 PF02991 0.717
LIG_LIR_Gen_1 567 577 PF02991 0.539
LIG_LIR_Nem_3 1112 1117 PF02991 0.558
LIG_LIR_Nem_3 1147 1153 PF02991 0.289
LIG_LIR_Nem_3 1349 1354 PF02991 0.493
LIG_LIR_Nem_3 1492 1498 PF02991 0.587
LIG_LIR_Nem_3 1610 1616 PF02991 0.593
LIG_LIR_Nem_3 1696 1701 PF02991 0.629
LIG_LIR_Nem_3 1742 1748 PF02991 0.541
LIG_LIR_Nem_3 19 23 PF02991 0.544
LIG_LIR_Nem_3 233 239 PF02991 0.700
LIG_LIR_Nem_3 275 281 PF02991 0.574
LIG_LIR_Nem_3 419 424 PF02991 0.399
LIG_LIR_Nem_3 47 51 PF02991 0.733
LIG_LIR_Nem_3 546 552 PF02991 0.314
LIG_LIR_Nem_3 567 572 PF02991 0.532
LIG_LIR_Nem_3 954 958 PF02991 0.539
LIG_LIR_Nem_3 961 966 PF02991 0.577
LIG_NRBOX 1404 1410 PF00104 0.335
LIG_NRBOX 276 282 PF00104 0.477
LIG_NRBOX 748 754 PF00104 0.502
LIG_PCNA_APIM_2 66 72 PF02747 0.462
LIG_PCNA_yPIPBox_3 1294 1308 PF02747 0.480
LIG_PCNA_yPIPBox_3 647 658 PF02747 0.532
LIG_Pex14_1 1154 1158 PF04695 0.258
LIG_Pex14_1 487 491 PF04695 0.473
LIG_Pex14_1 518 522 PF04695 0.303
LIG_Pex14_1 73 77 PF04695 0.523
LIG_Pex14_2 1189 1193 PF04695 0.279
LIG_Rb_LxCxE_1 813 832 PF01857 0.421
LIG_REV1ctd_RIR_1 1214 1220 PF16727 0.526
LIG_SH2_CRK 1263 1267 PF00017 0.329
LIG_SH2_CRK 1277 1281 PF00017 0.427
LIG_SH2_CRK 1286 1290 PF00017 0.340
LIG_SH2_CRK 1566 1570 PF00017 0.488
LIG_SH2_CRK 1701 1705 PF00017 0.623
LIG_SH2_CRK 1716 1720 PF00017 0.479
LIG_SH2_CRK 1745 1749 PF00017 0.490
LIG_SH2_CRK 90 94 PF00017 0.503
LIG_SH2_NCK_1 1566 1570 PF00017 0.488
LIG_SH2_NCK_1 1701 1705 PF00017 0.577
LIG_SH2_NCK_1 714 718 PF00017 0.557
LIG_SH2_PTP2 77 80 PF00017 0.553
LIG_SH2_SRC 1428 1431 PF00017 0.566
LIG_SH2_SRC 966 969 PF00017 0.594
LIG_SH2_STAP1 1277 1281 PF00017 0.363
LIG_SH2_STAP1 1286 1290 PF00017 0.350
LIG_SH2_STAP1 1339 1343 PF00017 0.462
LIG_SH2_STAP1 1716 1720 PF00017 0.529
LIG_SH2_STAP1 955 959 PF00017 0.525
LIG_SH2_STAT3 237 240 PF00017 0.621
LIG_SH2_STAT3 770 773 PF00017 0.490
LIG_SH2_STAT5 1120 1123 PF00017 0.554
LIG_SH2_STAT5 1137 1140 PF00017 0.441
LIG_SH2_STAT5 1158 1161 PF00017 0.276
LIG_SH2_STAT5 1172 1175 PF00017 0.318
LIG_SH2_STAT5 1207 1210 PF00017 0.501
LIG_SH2_STAT5 1253 1256 PF00017 0.340
LIG_SH2_STAT5 1343 1346 PF00017 0.468
LIG_SH2_STAT5 1358 1361 PF00017 0.305
LIG_SH2_STAT5 1428 1431 PF00017 0.570
LIG_SH2_STAT5 1445 1448 PF00017 0.593
LIG_SH2_STAT5 1566 1569 PF00017 0.488
LIG_SH2_STAT5 1701 1704 PF00017 0.585
LIG_SH2_STAT5 187 190 PF00017 0.624
LIG_SH2_STAT5 250 253 PF00017 0.605
LIG_SH2_STAT5 421 424 PF00017 0.379
LIG_SH2_STAT5 536 539 PF00017 0.349
LIG_SH2_STAT5 69 72 PF00017 0.567
LIG_SH2_STAT5 77 80 PF00017 0.568
LIG_SH2_STAT5 770 773 PF00017 0.490
LIG_SH2_STAT5 894 897 PF00017 0.494
LIG_SH2_STAT5 966 969 PF00017 0.623
LIG_SH3_1 1506 1512 PF00018 0.644
LIG_SH3_3 1378 1384 PF00018 0.384
LIG_SH3_3 1506 1512 PF00018 0.644
LIG_SH3_3 1576 1582 PF00018 0.515
LIG_SH3_3 265 271 PF00018 0.710
LIG_SH3_3 3 9 PF00018 0.638
LIG_SH3_3 300 306 PF00018 0.289
LIG_SH3_3 544 550 PF00018 0.336
LIG_SH3_3 627 633 PF00018 0.685
LIG_SH3_3 635 641 PF00018 0.709
LIG_SH3_3 724 730 PF00018 0.506
LIG_SH3_3 769 775 PF00018 0.507
LIG_SUMO_SIM_anti_2 1265 1271 PF11976 0.256
LIG_SUMO_SIM_anti_2 1361 1366 PF11976 0.383
LIG_SUMO_SIM_anti_2 1717 1723 PF11976 0.553
LIG_SUMO_SIM_anti_2 333 339 PF11976 0.388
LIG_SUMO_SIM_anti_2 362 370 PF11976 0.499
LIG_SUMO_SIM_anti_2 854 859 PF11976 0.548
LIG_SUMO_SIM_anti_2 939 946 PF11976 0.517
LIG_SUMO_SIM_par_1 1177 1182 PF11976 0.222
LIG_SUMO_SIM_par_1 1302 1310 PF11976 0.421
LIG_SUMO_SIM_par_1 1389 1394 PF11976 0.313
LIG_SUMO_SIM_par_1 1511 1517 PF11976 0.569
LIG_SUMO_SIM_par_1 1547 1552 PF11976 0.479
LIG_SUMO_SIM_par_1 550 556 PF11976 0.373
LIG_TRAF2_1 1009 1012 PF00917 0.757
LIG_TRAF2_1 1103 1106 PF00917 0.633
LIG_TRAF2_1 1600 1603 PF00917 0.488
LIG_TRAF2_1 58 61 PF00917 0.574
LIG_TYR_ITIM 1743 1748 PF00017 0.327
LIG_TYR_ITIM 422 427 PF00017 0.298
LIG_UBA3_1 330 339 PF00899 0.237
LIG_UBA3_1 475 483 PF00899 0.255
LIG_WRC_WIRS_1 17 22 PF05994 0.412
LIG_WRC_WIRS_1 281 286 PF05994 0.354
MOD_CDC14_SPxK_1 813 816 PF00782 0.337
MOD_CDK_SPxK_1 810 816 PF00069 0.337
MOD_CDK_SPxxK_3 1035 1042 PF00069 0.682
MOD_CDK_SPxxK_3 1217 1224 PF00069 0.334
MOD_CK1_1 1048 1054 PF00069 0.574
MOD_CK1_1 1087 1093 PF00069 0.512
MOD_CK1_1 1144 1150 PF00069 0.365
MOD_CK1_1 1161 1167 PF00069 0.346
MOD_CK1_1 1210 1216 PF00069 0.381
MOD_CK1_1 1265 1271 PF00069 0.282
MOD_CK1_1 1418 1424 PF00069 0.396
MOD_CK1_1 142 148 PF00069 0.478
MOD_CK1_1 1453 1459 PF00069 0.515
MOD_CK1_1 1463 1469 PF00069 0.575
MOD_CK1_1 1536 1542 PF00069 0.356
MOD_CK1_1 16 22 PF00069 0.567
MOD_CK1_1 1619 1625 PF00069 0.238
MOD_CK1_1 1631 1637 PF00069 0.218
MOD_CK1_1 1649 1655 PF00069 0.280
MOD_CK1_1 190 196 PF00069 0.413
MOD_CK1_1 462 468 PF00069 0.328
MOD_CK1_1 523 529 PF00069 0.491
MOD_CK1_1 556 562 PF00069 0.358
MOD_CK1_1 604 610 PF00069 0.521
MOD_CK1_1 619 625 PF00069 0.565
MOD_CK1_1 743 749 PF00069 0.359
MOD_CK1_1 976 982 PF00069 0.737
MOD_CK1_1 995 1001 PF00069 0.539
MOD_CK2_1 1006 1012 PF00069 0.656
MOD_CK2_1 1051 1057 PF00069 0.621
MOD_CK2_1 1087 1093 PF00069 0.621
MOD_CK2_1 1100 1106 PF00069 0.514
MOD_CK2_1 1161 1167 PF00069 0.389
MOD_CK2_1 1303 1309 PF00069 0.336
MOD_CK2_1 1339 1345 PF00069 0.306
MOD_CK2_1 1597 1603 PF00069 0.355
MOD_CK2_1 16 22 PF00069 0.442
MOD_CK2_1 315 321 PF00069 0.220
MOD_CK2_1 393 399 PF00069 0.412
MOD_CK2_1 490 496 PF00069 0.313
MOD_CK2_1 784 790 PF00069 0.329
MOD_CK2_1 983 989 PF00069 0.629
MOD_Cter_Amidation 680 683 PF01082 0.518
MOD_Cter_Amidation 907 910 PF01082 0.366
MOD_GlcNHglycan 1086 1089 PF01048 0.702
MOD_GlcNHglycan 1183 1186 PF01048 0.303
MOD_GlcNHglycan 1210 1213 PF01048 0.370
MOD_GlcNHglycan 139 144 PF01048 0.473
MOD_GlcNHglycan 1405 1408 PF01048 0.430
MOD_GlcNHglycan 1452 1455 PF01048 0.670
MOD_GlcNHglycan 1465 1468 PF01048 0.578
MOD_GlcNHglycan 1491 1494 PF01048 0.541
MOD_GlcNHglycan 1535 1538 PF01048 0.357
MOD_GlcNHglycan 1550 1554 PF01048 0.356
MOD_GlcNHglycan 1619 1622 PF01048 0.346
MOD_GlcNHglycan 1626 1629 PF01048 0.306
MOD_GlcNHglycan 1630 1633 PF01048 0.274
MOD_GlcNHglycan 1669 1672 PF01048 0.412
MOD_GlcNHglycan 1750 1753 PF01048 0.602
MOD_GlcNHglycan 1770 1773 PF01048 0.714
MOD_GlcNHglycan 206 209 PF01048 0.455
MOD_GlcNHglycan 38 41 PF01048 0.489
MOD_GlcNHglycan 431 434 PF01048 0.399
MOD_GlcNHglycan 476 479 PF01048 0.339
MOD_GlcNHglycan 492 495 PF01048 0.345
MOD_GlcNHglycan 538 541 PF01048 0.290
MOD_GlcNHglycan 555 558 PF01048 0.337
MOD_GlcNHglycan 60 65 PF01048 0.386
MOD_GlcNHglycan 606 609 PF01048 0.674
MOD_GlcNHglycan 611 614 PF01048 0.660
MOD_GlcNHglycan 618 621 PF01048 0.473
MOD_GlcNHglycan 708 711 PF01048 0.543
MOD_GlcNHglycan 742 745 PF01048 0.356
MOD_GlcNHglycan 805 808 PF01048 0.264
MOD_GlcNHglycan 873 876 PF01048 0.336
MOD_GlcNHglycan 900 903 PF01048 0.447
MOD_GlcNHglycan 978 981 PF01048 0.683
MOD_GlcNHglycan 994 997 PF01048 0.778
MOD_GlcNHglycan 998 1001 PF01048 0.767
MOD_GSK3_1 1002 1009 PF00069 0.546
MOD_GSK3_1 1079 1086 PF00069 0.642
MOD_GSK3_1 1137 1144 PF00069 0.388
MOD_GSK3_1 1145 1152 PF00069 0.336
MOD_GSK3_1 1158 1165 PF00069 0.333
MOD_GSK3_1 1208 1215 PF00069 0.273
MOD_GSK3_1 1254 1261 PF00069 0.331
MOD_GSK3_1 1295 1302 PF00069 0.344
MOD_GSK3_1 1389 1396 PF00069 0.314
MOD_GSK3_1 1399 1406 PF00069 0.354
MOD_GSK3_1 1461 1468 PF00069 0.584
MOD_GSK3_1 1533 1540 PF00069 0.431
MOD_GSK3_1 1624 1631 PF00069 0.217
MOD_GSK3_1 1768 1775 PF00069 0.633
MOD_GSK3_1 350 357 PF00069 0.424
MOD_GSK3_1 486 493 PF00069 0.347
MOD_GSK3_1 532 539 PF00069 0.357
MOD_GSK3_1 576 583 PF00069 0.359
MOD_GSK3_1 60 67 PF00069 0.407
MOD_GSK3_1 760 767 PF00069 0.466
MOD_GSK3_1 801 808 PF00069 0.362
MOD_GSK3_1 988 995 PF00069 0.645
MOD_N-GLC_1 1649 1654 PF02516 0.385
MOD_N-GLC_1 459 464 PF02516 0.255
MOD_N-GLC_1 602 607 PF02516 0.454
MOD_N-GLC_1 784 789 PF02516 0.333
MOD_N-GLC_1 871 876 PF02516 0.334
MOD_NEK2_1 1159 1164 PF00069 0.347
MOD_NEK2_1 1205 1210 PF00069 0.300
MOD_NEK2_1 1248 1253 PF00069 0.302
MOD_NEK2_1 1258 1263 PF00069 0.348
MOD_NEK2_1 1285 1290 PF00069 0.368
MOD_NEK2_1 1337 1342 PF00069 0.403
MOD_NEK2_1 1393 1398 PF00069 0.346
MOD_NEK2_1 1399 1404 PF00069 0.334
MOD_NEK2_1 1585 1590 PF00069 0.387
MOD_NEK2_1 1686 1691 PF00069 0.355
MOD_NEK2_1 280 285 PF00069 0.379
MOD_NEK2_1 29 34 PF00069 0.439
MOD_NEK2_1 315 320 PF00069 0.374
MOD_NEK2_1 330 335 PF00069 0.318
MOD_NEK2_1 350 355 PF00069 0.473
MOD_NEK2_1 359 364 PF00069 0.353
MOD_NEK2_1 543 548 PF00069 0.324
MOD_NEK2_1 575 580 PF00069 0.404
MOD_NEK2_1 601 606 PF00069 0.465
MOD_NEK2_1 748 753 PF00069 0.322
MOD_NEK2_1 951 956 PF00069 0.462
MOD_NEK2_2 1212 1217 PF00069 0.297
MOD_NEK2_2 13 18 PF00069 0.544
MOD_NEK2_2 784 789 PF00069 0.337
MOD_PIKK_1 580 586 PF00454 0.434
MOD_PK_1 1295 1301 PF00069 0.348
MOD_PK_1 1739 1745 PF00069 0.381
MOD_PKA_1 1294 1300 PF00069 0.350
MOD_PKA_1 1667 1673 PF00069 0.434
MOD_PKA_1 1739 1745 PF00069 0.335
MOD_PKA_1 354 360 PF00069 0.318
MOD_PKA_2 1023 1029 PF00069 0.567
MOD_PKA_2 1061 1067 PF00069 0.588
MOD_PKA_2 1227 1233 PF00069 0.318
MOD_PKA_2 1294 1300 PF00069 0.294
MOD_PKA_2 1314 1320 PF00069 0.516
MOD_PKA_2 1739 1745 PF00069 0.504
MOD_PKA_2 188 194 PF00069 0.475
MOD_PKA_2 244 250 PF00069 0.457
MOD_PKA_2 354 360 PF00069 0.337
MOD_PKA_2 469 475 PF00069 0.354
MOD_PKA_2 580 586 PF00069 0.375
MOD_PKA_2 704 710 PF00069 0.514
MOD_PKA_2 725 731 PF00069 0.309
MOD_PKA_2 879 885 PF00069 0.353
MOD_PKB_1 1774 1782 PF00069 0.529
MOD_PKB_1 352 360 PF00069 0.318
MOD_Plk_1 1062 1068 PF00069 0.686
MOD_Plk_1 1321 1327 PF00069 0.425
MOD_Plk_1 1399 1405 PF00069 0.325
MOD_Plk_1 1415 1421 PF00069 0.462
MOD_Plk_1 1649 1655 PF00069 0.381
MOD_Plk_1 165 171 PF00069 0.403
MOD_Plk_1 1686 1692 PF00069 0.383
MOD_Plk_1 543 549 PF00069 0.337
MOD_Plk_1 588 594 PF00069 0.395
MOD_Plk_1 784 790 PF00069 0.333
MOD_Plk_4 1145 1151 PF00069 0.315
MOD_Plk_4 1212 1218 PF00069 0.280
MOD_Plk_4 1258 1264 PF00069 0.367
MOD_Plk_4 1265 1271 PF00069 0.367
MOD_Plk_4 1285 1291 PF00069 0.498
MOD_Plk_4 13 19 PF00069 0.537
MOD_Plk_4 1303 1309 PF00069 0.480
MOD_Plk_4 1339 1345 PF00069 0.320
MOD_Plk_4 1346 1352 PF00069 0.316
MOD_Plk_4 1537 1543 PF00069 0.356
MOD_Plk_4 1639 1645 PF00069 0.319
MOD_Plk_4 1699 1705 PF00069 0.450
MOD_Plk_4 1739 1745 PF00069 0.471
MOD_Plk_4 1797 1803 PF00069 0.377
MOD_Plk_4 193 199 PF00069 0.403
MOD_Plk_4 272 278 PF00069 0.485
MOD_Plk_4 355 361 PF00069 0.401
MOD_Plk_4 413 419 PF00069 0.309
MOD_Plk_4 523 529 PF00069 0.355
MOD_Plk_4 543 549 PF00069 0.346
MOD_Plk_4 732 738 PF00069 0.361
MOD_Plk_4 743 749 PF00069 0.289
MOD_ProDKin_1 1035 1041 PF00069 0.681
MOD_ProDKin_1 1109 1115 PF00069 0.398
MOD_ProDKin_1 1217 1223 PF00069 0.334
MOD_ProDKin_1 1262 1268 PF00069 0.337
MOD_ProDKin_1 1299 1305 PF00069 0.334
MOD_ProDKin_1 1377 1383 PF00069 0.505
MOD_ProDKin_1 190 196 PF00069 0.595
MOD_ProDKin_1 302 308 PF00069 0.414
MOD_ProDKin_1 373 379 PF00069 0.281
MOD_ProDKin_1 521 527 PF00069 0.423
MOD_ProDKin_1 671 677 PF00069 0.666
MOD_ProDKin_1 810 816 PF00069 0.337
MOD_SUMO_rev_2 1100 1109 PF00179 0.619
MOD_SUMO_rev_2 961 965 PF00179 0.391
TRG_DiLeu_BaLyEn_6 1300 1305 PF01217 0.237
TRG_DiLeu_BaLyEn_6 547 552 PF01217 0.368
TRG_ENDOCYTIC_2 1172 1175 PF00928 0.302
TRG_ENDOCYTIC_2 1277 1280 PF00928 0.315
TRG_ENDOCYTIC_2 1286 1289 PF00928 0.400
TRG_ENDOCYTIC_2 1701 1704 PF00928 0.522
TRG_ENDOCYTIC_2 1716 1719 PF00928 0.323
TRG_ENDOCYTIC_2 1745 1748 PF00928 0.329
TRG_ENDOCYTIC_2 424 427 PF00928 0.346
TRG_ENDOCYTIC_2 714 717 PF00928 0.442
TRG_ENDOCYTIC_2 77 80 PF00928 0.418
TRG_ER_diArg_1 123 126 PF00400 0.469
TRG_ER_diArg_1 1293 1296 PF00400 0.319
TRG_ER_diArg_1 1571 1573 PF00400 0.378
TRG_ER_diArg_1 169 172 PF00400 0.377
TRG_ER_diArg_1 1724 1727 PF00400 0.335
TRG_ER_diArg_1 181 184 PF00400 0.451
TRG_ER_diArg_1 212 215 PF00400 0.528
TRG_ER_diArg_1 25 27 PF00400 0.576
TRG_ER_diArg_1 352 355 PF00400 0.340
TRG_ER_diArg_1 468 471 PF00400 0.365
TRG_ER_diArg_1 506 509 PF00400 0.436
TRG_ER_diArg_1 646 648 PF00400 0.519
TRG_ER_diArg_1 658 661 PF00400 0.523
TRG_ER_diArg_1 668 670 PF00400 0.650
TRG_ER_diArg_1 909 911 PF00400 0.523
TRG_NES_CRM1_1 474 488 PF08389 0.228
TRG_Pf-PMV_PEXEL_1 1734 1738 PF00026 0.473
TRG_Pf-PMV_PEXEL_1 52 56 PF00026 0.677
TRG_Pf-PMV_PEXEL_1 719 724 PF00026 0.348
TRG_Pf-PMV_PEXEL_1 860 865 PF00026 0.228

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P657 Leptomonas seymouri 61% 100%
A0A0N1IGL0 Leptomonas seymouri 34% 100%
A0A3Q8III5 Leishmania donovani 42% 100%
A0A3S5ISD8 Trypanosoma rangeli 35% 100%
A0A3S7X4I0 Leishmania donovani 99% 100%
A4HCN5 Leishmania braziliensis 37% 92%
A4HCT5 Leishmania braziliensis 37% 92%
A4HJB1 Leishmania braziliensis 43% 100%
A4HJC5 Leishmania braziliensis 74% 100%
A4I6Q5 Leishmania infantum 42% 100%
C9ZM88 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
E9AW22 Leishmania mexicana (strain MHOM/GT/2001/U1103) 38% 92%
E9AW23 Leishmania mexicana (strain MHOM/GT/2001/U1103) 38% 92%
E9B1S6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 43% 100%
E9B1S7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 43% 100%
E9B1U2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%
Q4Q6B9 Leishmania major 90% 100%
Q4Q6D4 Leishmania major 42% 100%
Q4Q6D5 Leishmania major 43% 100%
Q4QBF4 Leishmania major 38% 91%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS