Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I6R9_LEIIN

TriTrypDb:

LINF_310021000

Length:

1157

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I6R9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6R9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1137	1141	PF00656	0.624
CLV_C14_Caspase3-7	220	224	PF00656	0.642
CLV_C14_Caspase3-7	465	469	PF00656	0.601
CLV_C14_Caspase3-7	53	57	PF00656	0.666
CLV_C14_Caspase3-7	703	707	PF00656	0.726
CLV_NRD_NRD_1	1068	1070	PF00675	0.610
CLV_NRD_NRD_1	1085	1087	PF00675	0.613
CLV_NRD_NRD_1	118	120	PF00675	0.586
CLV_NRD_NRD_1	187	189	PF00675	0.713
CLV_NRD_NRD_1	19	21	PF00675	0.613
CLV_NRD_NRD_1	260	262	PF00675	0.636
CLV_NRD_NRD_1	30	32	PF00675	0.543
CLV_NRD_NRD_1	328	330	PF00675	0.699
CLV_NRD_NRD_1	370	372	PF00675	0.567
CLV_NRD_NRD_1	377	379	PF00675	0.474
CLV_NRD_NRD_1	82	84	PF00675	0.643
CLV_NRD_NRD_1	841	843	PF00675	0.683
CLV_NRD_NRD_1	847	849	PF00675	0.647
CLV_NRD_NRD_1	985	987	PF00675	0.730
CLV_PCSK_FUR_1	845	849	PF00082	0.684
CLV_PCSK_KEX2_1	1068	1070	PF00082	0.603
CLV_PCSK_KEX2_1	187	189	PF00082	0.724
CLV_PCSK_KEX2_1	260	262	PF00082	0.636
CLV_PCSK_KEX2_1	29	31	PF00082	0.694
CLV_PCSK_KEX2_1	328	330	PF00082	0.699
CLV_PCSK_KEX2_1	370	372	PF00082	0.567
CLV_PCSK_KEX2_1	377	379	PF00082	0.474
CLV_PCSK_KEX2_1	82	84	PF00082	0.643
CLV_PCSK_KEX2_1	841	843	PF00082	0.683
CLV_PCSK_KEX2_1	847	849	PF00082	0.647
CLV_PCSK_KEX2_1	963	965	PF00082	0.737
CLV_PCSK_KEX2_1	985	987	PF00082	0.730
CLV_PCSK_PC1ET2_1	963	965	PF00082	0.737
CLV_PCSK_PC7_1	26	32	PF00082	0.631
CLV_PCSK_SKI1_1	1091	1095	PF00082	0.728
CLV_PCSK_SKI1_1	314	318	PF00082	0.554
CLV_PCSK_SKI1_1	847	851	PF00082	0.668
CLV_PCSK_SKI1_1	889	893	PF00082	0.600
DEG_APCC_DBOX_1	846	854	PF00400	0.625
DOC_AGCK_PIF_2	722	727	PF00069	0.622
DOC_CDC14_PxL_1	347	355	PF14671	0.526
DOC_CKS1_1	966	971	PF01111	0.679
DOC_CYCLIN_RxL_1	842	855	PF00134	0.623
DOC_MAPK_FxFP_2	207	210	PF00069	0.644
DOC_MAPK_gen_1	187	198	PF00069	0.537
DOC_MAPK_gen_1	26	36	PF00069	0.685
DOC_MAPK_gen_1	370	381	PF00069	0.545
DOC_MAPK_gen_1	841	851	PF00069	0.667
DOC_MAPK_MEF2A_6	845	853	PF00069	0.675
DOC_PP1_RVXF_1	1144	1150	PF00149	0.655
DOC_PP1_RVXF_1	406	412	PF00149	0.593
DOC_PP2B_LxvP_1	1071	1074	PF13499	0.707
DOC_PP2B_LxvP_1	272	275	PF13499	0.821
DOC_PP4_FxxP_1	207	210	PF00568	0.644
DOC_PP4_FxxP_1	271	274	PF00568	0.712
DOC_PP4_FxxP_1	46	49	PF00568	0.745
DOC_PP4_FxxP_1	564	567	PF00568	0.657
DOC_PP4_MxPP_1	635	638	PF00568	0.588
DOC_USP7_MATH_1	1054	1058	PF00917	0.578
DOC_USP7_MATH_1	144	148	PF00917	0.562
DOC_USP7_MATH_1	175	179	PF00917	0.740
DOC_USP7_MATH_1	210	214	PF00917	0.619
DOC_USP7_MATH_1	236	240	PF00917	0.687
DOC_USP7_MATH_1	244	248	PF00917	0.553
DOC_USP7_MATH_1	275	279	PF00917	0.671
DOC_USP7_MATH_1	337	341	PF00917	0.612
DOC_USP7_MATH_1	393	397	PF00917	0.439
DOC_USP7_MATH_1	440	444	PF00917	0.716
DOC_USP7_MATH_1	450	454	PF00917	0.656
DOC_USP7_MATH_1	480	484	PF00917	0.684
DOC_USP7_MATH_1	489	493	PF00917	0.622
DOC_USP7_MATH_1	591	595	PF00917	0.724
DOC_USP7_MATH_1	60	64	PF00917	0.673
DOC_USP7_MATH_1	611	615	PF00917	0.631
DOC_USP7_MATH_1	645	649	PF00917	0.725
DOC_USP7_MATH_1	659	663	PF00917	0.601
DOC_USP7_MATH_1	690	694	PF00917	0.672
DOC_USP7_MATH_1	709	713	PF00917	0.675
DOC_USP7_MATH_1	776	780	PF00917	0.802
DOC_USP7_MATH_1	825	829	PF00917	0.645
DOC_USP7_MATH_1	864	868	PF00917	0.709
DOC_USP7_MATH_1	921	925	PF00917	0.680
DOC_USP7_MATH_1	936	940	PF00917	0.552
DOC_USP7_MATH_1	942	946	PF00917	0.663
DOC_WW_Pin1_4	1	6	PF00397	0.708
DOC_WW_Pin1_4	1050	1055	PF00397	0.590
DOC_WW_Pin1_4	198	203	PF00397	0.619
DOC_WW_Pin1_4	411	416	PF00397	0.638
DOC_WW_Pin1_4	56	61	PF00397	0.697
DOC_WW_Pin1_4	646	651	PF00397	0.651
DOC_WW_Pin1_4	672	677	PF00397	0.680
DOC_WW_Pin1_4	686	691	PF00397	0.551
DOC_WW_Pin1_4	711	716	PF00397	0.627
DOC_WW_Pin1_4	965	970	PF00397	0.727
LIG_14-3-3_CanoR_1	1068	1072	PF00244	0.633
LIG_14-3-3_CanoR_1	188	198	PF00244	0.656
LIG_14-3-3_CanoR_1	342	350	PF00244	0.578
LIG_14-3-3_CanoR_1	588	596	PF00244	0.647
LIG_14-3-3_CanoR_1	671	676	PF00244	0.718
LIG_14-3-3_CanoR_1	841	845	PF00244	0.686
LIG_14-3-3_CanoR_1	848	854	PF00244	0.620
LIG_Actin_WH2_2	343	359	PF00022	0.537
LIG_BIR_III_2	93	97	PF00653	0.649
LIG_BIR_III_4	1140	1144	PF00653	0.619
LIG_BRCT_BRCA1_1	238	242	PF00533	0.641
LIG_BRCT_BRCA1_1	339	343	PF00533	0.616
LIG_BRCT_BRCA1_1	351	355	PF00533	0.379
LIG_BRCT_BRCA1_1	906	910	PF00533	0.716
LIG_BRCT_BRCA1_1	939	943	PF00533	0.679
LIG_BRCT_BRCA1_1	97	101	PF00533	0.618
LIG_CaM_IQ_9	363	379	PF13499	0.548
LIG_FHA_1	191	197	PF00498	0.549
LIG_FHA_1	209	215	PF00498	0.694
LIG_FHA_1	367	373	PF00498	0.554
LIG_FHA_1	414	420	PF00498	0.592
LIG_FHA_1	505	511	PF00498	0.624
LIG_FHA_1	514	520	PF00498	0.468
LIG_FHA_1	733	739	PF00498	0.712
LIG_FHA_1	784	790	PF00498	0.688
LIG_FHA_1	904	910	PF00498	0.582
LIG_FHA_2	1007	1013	PF00498	0.655
LIG_FHA_2	154	160	PF00498	0.640
LIG_FHA_2	288	294	PF00498	0.694
LIG_FHA_2	51	57	PF00498	0.662
LIG_FHA_2	528	534	PF00498	0.636
LIG_FHA_2	778	784	PF00498	0.581
LIG_FHA_2	966	972	PF00498	0.726
LIG_GBD_Chelix_1	394	402	PF00786	0.510
LIG_LIR_Apic_2	269	274	PF02991	0.707
LIG_LIR_Apic_2	562	567	PF02991	0.661
LIG_LIR_Gen_1	247	256	PF02991	0.651
LIG_LIR_Gen_1	296	303	PF02991	0.612
LIG_LIR_Gen_1	340	351	PF02991	0.579
LIG_LIR_Gen_1	40	49	PF02991	0.630
LIG_LIR_Gen_1	404	413	PF02991	0.535
LIG_LIR_Nem_3	1040	1044	PF02991	0.703
LIG_LIR_Nem_3	1150	1154	PF02991	0.616
LIG_LIR_Nem_3	121	126	PF02991	0.615
LIG_LIR_Nem_3	132	138	PF02991	0.550
LIG_LIR_Nem_3	247	251	PF02991	0.645
LIG_LIR_Nem_3	296	300	PF02991	0.629
LIG_LIR_Nem_3	340	346	PF02991	0.721
LIG_LIR_Nem_3	40	46	PF02991	0.626
LIG_LIR_Nem_3	404	409	PF02991	0.499
LIG_LYPXL_yS_3	135	138	PF13949	0.574
LIG_Pex14_1	618	622	PF04695	0.692
LIG_Pex14_2	317	321	PF04695	0.517
LIG_PTB_Apo_2	964	971	PF02174	0.730
LIG_PTB_Phospho_1	964	970	PF10480	0.730
LIG_Rb_LxCxE_1	358	369	PF01857	0.489
LIG_SH2_GRB2like	859	862	PF00017	0.647
LIG_SH2_GRB2like	965	968	PF00017	0.730
LIG_SH2_NCK_1	297	301	PF00017	0.622
LIG_SH2_SRC	859	862	PF00017	0.599
LIG_SH2_SRC	970	973	PF00017	0.723
LIG_SH2_STAP1	142	146	PF00017	0.630
LIG_SH2_STAP1	297	301	PF00017	0.622
LIG_SH2_STAP1	575	579	PF00017	0.701
LIG_SH2_STAT3	164	167	PF00017	0.604
LIG_SH2_STAT3	323	326	PF00017	0.528
LIG_SH2_STAT5	117	120	PF00017	0.575
LIG_SH2_STAT5	13	16	PF00017	0.597
LIG_SH2_STAT5	323	326	PF00017	0.606
LIG_SH2_STAT5	605	608	PF00017	0.691
LIG_SH2_STAT5	627	630	PF00017	0.692
LIG_SH2_STAT5	723	726	PF00017	0.693
LIG_SH2_STAT5	734	737	PF00017	0.638
LIG_SH2_STAT5	85	88	PF00017	0.685
LIG_SH2_STAT5	932	935	PF00017	0.605
LIG_SH2_STAT5	965	968	PF00017	0.682
LIG_SH3_2	658	663	PF14604	0.741
LIG_SH3_3	1090	1096	PF00018	0.716
LIG_SH3_3	1118	1124	PF00018	0.817
LIG_SH3_3	238	244	PF00018	0.657
LIG_SH3_3	330	336	PF00018	0.596
LIG_SH3_3	412	418	PF00018	0.592
LIG_SH3_3	521	527	PF00018	0.649
LIG_SH3_3	631	637	PF00018	0.677
LIG_SH3_3	644	650	PF00018	0.653
LIG_SH3_3	655	661	PF00018	0.668
LIG_SH3_3	950	956	PF00018	0.729
LIG_SH3_3	963	969	PF00018	0.597
LIG_SUMO_SIM_anti_2	33	38	PF11976	0.675
LIG_SUMO_SIM_par_1	849	855	PF11976	0.667
LIG_TRAF2_1	555	558	PF00917	0.634
LIG_TRAF2_1	581	584	PF00917	0.587
LIG_TRAF2_2	637	642	PF00917	0.607
LIG_TYR_ITIM	133	138	PF00017	0.577
LIG_UBA3_1	36	42	PF00899	0.686
LIG_WRC_WIRS_1	138	143	PF05994	0.574
LIG_WW_2	336	339	PF00397	0.597
LIG_WW_3	216	220	PF00397	0.654
MOD_CDC14_SPxK_1	4	7	PF00782	0.602
MOD_CDK_SPxK_1	1	7	PF00069	0.635
MOD_CK1_1	122	128	PF00069	0.733
MOD_CK1_1	267	273	PF00069	0.703
MOD_CK1_1	453	459	PF00069	0.653
MOD_CK1_1	51	57	PF00069	0.688
MOD_CK1_1	648	654	PF00069	0.715
MOD_CK1_1	65	71	PF00069	0.713
MOD_CK1_1	675	681	PF00069	0.696
MOD_CK1_1	686	692	PF00069	0.598
MOD_CK1_1	74	80	PF00069	0.657
MOD_CK1_1	799	805	PF00069	0.723
MOD_CK1_1	812	818	PF00069	0.600
MOD_CK1_1	827	833	PF00069	0.556
MOD_CK1_1	852	858	PF00069	0.714
MOD_CK1_1	875	881	PF00069	0.742
MOD_CK1_1	895	901	PF00069	0.590
MOD_CK2_1	1050	1056	PF00069	0.643
MOD_CK2_1	1150	1156	PF00069	0.596
MOD_CK2_1	144	150	PF00069	0.639
MOD_CK2_1	287	293	PF00069	0.662
MOD_CK2_1	303	309	PF00069	0.593
MOD_CK2_1	527	533	PF00069	0.635
MOD_CK2_1	552	558	PF00069	0.679
MOD_CK2_1	763	769	PF00069	0.715
MOD_CK2_1	932	938	PF00069	0.686
MOD_CK2_1	965	971	PF00069	0.697
MOD_Cter_Amidation	1066	1069	PF01082	0.594
MOD_Cter_Amidation	839	842	PF01082	0.608
MOD_DYRK1A_RPxSP_1	646	650	PF00069	0.638
MOD_GlcNHglycan	1056	1059	PF01048	0.687
MOD_GlcNHglycan	225	228	PF01048	0.758
MOD_GlcNHglycan	266	269	PF01048	0.688
MOD_GlcNHglycan	277	280	PF01048	0.594
MOD_GlcNHglycan	305	308	PF01048	0.595
MOD_GlcNHglycan	430	433	PF01048	0.771
MOD_GlcNHglycan	442	445	PF01048	0.740
MOD_GlcNHglycan	453	456	PF01048	0.669
MOD_GlcNHglycan	478	481	PF01048	0.703
MOD_GlcNHglycan	482	485	PF01048	0.692
MOD_GlcNHglycan	499	502	PF01048	0.596
MOD_GlcNHglycan	50	53	PF01048	0.630
MOD_GlcNHglycan	553	557	PF01048	0.722
MOD_GlcNHglycan	62	65	PF01048	0.738
MOD_GlcNHglycan	711	714	PF01048	0.700
MOD_GlcNHglycan	786	789	PF01048	0.779
MOD_GlcNHglycan	798	801	PF01048	0.592
MOD_GlcNHglycan	817	820	PF01048	0.532
MOD_GlcNHglycan	838	841	PF01048	0.671
MOD_GlcNHglycan	866	869	PF01048	0.754
MOD_GlcNHglycan	872	875	PF01048	0.768
MOD_GlcNHglycan	897	900	PF01048	0.731
MOD_GlcNHglycan	923	926	PF01048	0.710
MOD_GlcNHglycan	934	937	PF01048	0.597
MOD_GlcNHglycan	938	942	PF01048	0.560
MOD_GlcNHglycan	948	951	PF01048	0.630
MOD_GSK3_1	1018	1025	PF00069	0.657
MOD_GSK3_1	1050	1057	PF00069	0.649
MOD_GSK3_1	337	344	PF00069	0.609
MOD_GSK3_1	462	469	PF00069	0.580
MOD_GSK3_1	476	483	PF00069	0.664
MOD_GSK3_1	490	497	PF00069	0.673
MOD_GSK3_1	50	57	PF00069	0.709
MOD_GSK3_1	513	520	PF00069	0.682
MOD_GSK3_1	58	65	PF00069	0.653
MOD_GSK3_1	587	594	PF00069	0.702
MOD_GSK3_1	648	655	PF00069	0.682
MOD_GSK3_1	661	668	PF00069	0.663
MOD_GSK3_1	67	74	PF00069	0.814
MOD_GSK3_1	671	678	PF00069	0.630
MOD_GSK3_1	686	693	PF00069	0.548
MOD_GSK3_1	792	799	PF00069	0.702
MOD_GSK3_1	805	812	PF00069	0.606
MOD_GSK3_1	821	828	PF00069	0.561
MOD_GSK3_1	836	843	PF00069	0.554
MOD_GSK3_1	932	939	PF00069	0.681
MOD_GSK3_1	942	949	PF00069	0.626
MOD_GSK3_1	985	992	PF00069	0.810
MOD_N-GLC_1	889	894	PF02516	0.599
MOD_N-GLC_1	910	915	PF02516	0.593
MOD_N-GLC_1	926	931	PF02516	0.609
MOD_N-GLC_2	231	233	PF02516	0.780
MOD_NEK2_1	1112	1117	PF00069	0.674
MOD_NEK2_1	366	371	PF00069	0.624
MOD_NEK2_1	462	467	PF00069	0.652
MOD_NEK2_1	598	603	PF00069	0.746
MOD_NEK2_1	677	682	PF00069	0.689
MOD_NEK2_1	849	854	PF00069	0.669
MOD_NEK2_2	144	149	PF00069	0.570
MOD_NEK2_2	504	509	PF00069	0.629
MOD_NEK2_2	840	845	PF00069	0.622
MOD_NMyristoyl	1	7	PF02799	0.804
MOD_PIKK_1	1073	1079	PF00454	0.647
MOD_PIKK_1	1105	1111	PF00454	0.673
MOD_PIKK_1	111	117	PF00454	0.633
MOD_PIKK_1	190	196	PF00454	0.623
MOD_PIKK_1	661	667	PF00454	0.742
MOD_PIKK_1	72	78	PF00454	0.627
MOD_PIKK_1	799	805	PF00454	0.723
MOD_PK_1	573	579	PF00069	0.701
MOD_PKA_1	119	125	PF00069	0.608
MOD_PKA_1	190	196	PF00069	0.641
MOD_PKA_1	985	991	PF00069	0.729
MOD_PKA_2	1067	1073	PF00069	0.627
MOD_PKA_2	341	347	PF00069	0.624
MOD_PKA_2	587	593	PF00069	0.625
MOD_PKA_2	645	651	PF00069	0.697
MOD_PKA_2	65	71	PF00069	0.701
MOD_PKA_2	78	84	PF00069	0.607
MOD_PKA_2	813	819	PF00069	0.732
MOD_PKA_2	840	846	PF00069	0.661
MOD_PKA_2	985	991	PF00069	0.729
MOD_Plk_1	32	38	PF00069	0.679
MOD_Plk_1	573	579	PF00069	0.809
MOD_Plk_1	892	898	PF00069	0.639
MOD_Plk_2-3	1150	1156	PF00069	0.596
MOD_Plk_2-3	790	796	PF00069	0.659
MOD_Plk_4	137	143	PF00069	0.650
MOD_Plk_4	236	242	PF00069	0.725
MOD_Plk_4	244	250	PF00069	0.668
MOD_Plk_4	267	273	PF00069	0.824
MOD_Plk_4	32	38	PF00069	0.679
MOD_Plk_4	527	533	PF00069	0.635
MOD_ProDKin_1	1	7	PF00069	0.701
MOD_ProDKin_1	1050	1056	PF00069	0.594
MOD_ProDKin_1	198	204	PF00069	0.617
MOD_ProDKin_1	411	417	PF00069	0.637
MOD_ProDKin_1	56	62	PF00069	0.700
MOD_ProDKin_1	646	652	PF00069	0.649
MOD_ProDKin_1	672	678	PF00069	0.675
MOD_ProDKin_1	686	692	PF00069	0.553
MOD_ProDKin_1	711	717	PF00069	0.624
MOD_ProDKin_1	965	971	PF00069	0.727
MOD_SUMO_rev_2	1137	1145	PF00179	0.577
TRG_DiLeu_BaEn_1	458	463	PF01217	0.654
TRG_DiLeu_BaEn_2	297	303	PF01217	0.610
TRG_DiLeu_BaEn_2	396	402	PF01217	0.512
TRG_ENDOCYTIC_2	1044	1047	PF00928	0.588
TRG_ENDOCYTIC_2	135	138	PF00928	0.653
TRG_ENDOCYTIC_2	297	300	PF00928	0.635
TRG_ER_diArg_1	259	261	PF00400	0.634
TRG_ER_diArg_1	29	31	PF00400	0.694
TRG_ER_diArg_1	359	362	PF00400	0.521
TRG_ER_diArg_1	370	372	PF00400	0.454
TRG_ER_diArg_1	376	378	PF00400	0.367
TRG_ER_diArg_1	844	847	PF00400	0.683
TRG_ER_diArg_1	985	987	PF00400	0.730
TRG_NLS_MonoCore_2	19	24	PF00514	0.545
TRG_NLS_MonoExtN_4	20	25	PF00514	0.599
TRG_Pf-PMV_PEXEL_1	1098	1102	PF00026	0.646
TRG_Pf-PMV_PEXEL_1	1152	1156	PF00026	0.598
TRG_Pf-PMV_PEXEL_1	314	318	PF00026	0.524
TRG_Pf-PMV_PEXEL_1	580	584	PF00026	0.622
TRG_Pf-PMV_PEXEL_1	985	989	PF00026	0.681

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X4F1	Leishmania donovani	100%	100%
A4HJC4	Leishmania braziliensis	74%	99%
E9B1U1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q6C0	Leishmania major	92%	100%