Proteophosphoglycan ppg4

Quick info Localization Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I6N2_LEIIN

TriTrypDb:

LINF_310016900

Length:

978

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4I6N2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6N2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	171	175	PF00656	0.434
CLV_C14_Caspase3-7	237	241	PF00656	0.429
CLV_NRD_NRD_1	130	132	PF00675	0.569
CLV_NRD_NRD_1	136	138	PF00675	0.469
CLV_NRD_NRD_1	157	159	PF00675	0.326
CLV_NRD_NRD_1	37	39	PF00675	0.632
CLV_NRD_NRD_1	70	72	PF00675	0.616
CLV_NRD_NRD_1	87	89	PF00675	0.403
CLV_NRD_NRD_1	95	97	PF00675	0.541
CLV_NRD_NRD_1	970	972	PF00675	0.615
CLV_NRD_NRD_1	976	978	PF00675	0.567
CLV_PCSK_FUR_1	67	71	PF00082	0.550
CLV_PCSK_KEX2_1	130	132	PF00082	0.569
CLV_PCSK_KEX2_1	135	137	PF00082	0.490
CLV_PCSK_KEX2_1	157	159	PF00082	0.326
CLV_PCSK_KEX2_1	37	39	PF00082	0.670
CLV_PCSK_KEX2_1	69	71	PF00082	0.621
CLV_PCSK_KEX2_1	87	89	PF00082	0.394
CLV_PCSK_KEX2_1	95	97	PF00082	0.541
CLV_PCSK_KEX2_1	976	978	PF00082	0.621
CLV_PCSK_PC7_1	131	137	PF00082	0.482
CLV_PCSK_PC7_1	153	159	PF00082	0.322
CLV_PCSK_SKI1_1	225	229	PF00082	0.450
CLV_PCSK_SKI1_1	922	926	PF00082	0.626
DEG_SPOP_SBC_1	274	278	PF00917	0.525
DEG_SPOP_SBC_1	287	291	PF00917	0.479
DEG_SPOP_SBC_1	437	441	PF00917	0.533
DEG_SPOP_SBC_1	487	491	PF00917	0.474
DEG_SPOP_SBC_1	552	556	PF00917	0.503
DEG_SPOP_SBC_1	585	589	PF00917	0.568
DEG_SPOP_SBC_1	624	628	PF00917	0.588
DEG_SPOP_SBC_1	727	731	PF00917	0.513
DOC_CKS1_1	395	400	PF01111	0.562
DOC_CKS1_1	498	503	PF01111	0.561
DOC_MAPK_gen_1	187	195	PF00069	0.402
DOC_MAPK_MEF2A_6	187	195	PF00069	0.447
DOC_MAPK_MEF2A_6	3	10	PF00069	0.541
DOC_PP4_FxxP_1	391	394	PF00568	0.599
DOC_PP4_FxxP_1	395	398	PF00568	0.558
DOC_PP4_FxxP_1	740	743	PF00568	0.543
DOC_PP4_FxxP_1	932	935	PF00568	0.610
DOC_PP4_MxPP_1	794	797	PF00568	0.587
DOC_USP7_MATH_1	112	116	PF00917	0.556
DOC_USP7_MATH_1	263	267	PF00917	0.556
DOC_USP7_MATH_1	272	276	PF00917	0.552
DOC_USP7_MATH_1	287	291	PF00917	0.463
DOC_USP7_MATH_1	319	323	PF00917	0.602
DOC_USP7_MATH_1	324	328	PF00917	0.560
DOC_USP7_MATH_1	400	404	PF00917	0.552
DOC_USP7_MATH_1	433	437	PF00917	0.607
DOC_USP7_MATH_1	445	449	PF00917	0.503
DOC_USP7_MATH_1	451	455	PF00917	0.466
DOC_USP7_MATH_1	462	466	PF00917	0.504
DOC_USP7_MATH_1	482	486	PF00917	0.482
DOC_USP7_MATH_1	488	492	PF00917	0.542
DOC_USP7_MATH_1	496	500	PF00917	0.507
DOC_USP7_MATH_1	503	507	PF00917	0.476
DOC_USP7_MATH_1	517	521	PF00917	0.475
DOC_USP7_MATH_1	537	541	PF00917	0.456
DOC_USP7_MATH_1	557	561	PF00917	0.525
DOC_USP7_MATH_1	657	661	PF00917	0.556
DOC_USP7_MATH_1	662	666	PF00917	0.570
DOC_USP7_MATH_1	673	677	PF00917	0.487
DOC_USP7_MATH_1	700	704	PF00917	0.575
DOC_USP7_MATH_1	716	720	PF00917	0.517
DOC_USP7_MATH_1	727	731	PF00917	0.496
DOC_USP7_MATH_1	732	736	PF00917	0.455
DOC_USP7_MATH_1	751	755	PF00917	0.457
DOC_USP7_MATH_1	868	872	PF00917	0.579
DOC_USP7_MATH_1	878	882	PF00917	0.520
DOC_USP7_MATH_1	920	924	PF00917	0.592
DOC_WW_Pin1_4	261	266	PF00397	0.512
DOC_WW_Pin1_4	270	275	PF00397	0.573
DOC_WW_Pin1_4	277	282	PF00397	0.521
DOC_WW_Pin1_4	322	327	PF00397	0.607
DOC_WW_Pin1_4	382	387	PF00397	0.565
DOC_WW_Pin1_4	394	399	PF00397	0.585
DOC_WW_Pin1_4	497	502	PF00397	0.567
DOC_WW_Pin1_4	523	528	PF00397	0.582
DOC_WW_Pin1_4	533	538	PF00397	0.495
DOC_WW_Pin1_4	553	558	PF00397	0.534
DOC_WW_Pin1_4	564	569	PF00397	0.530
DOC_WW_Pin1_4	625	630	PF00397	0.608
DOC_WW_Pin1_4	651	656	PF00397	0.561
DOC_WW_Pin1_4	696	701	PF00397	0.520
DOC_WW_Pin1_4	735	740	PF00397	0.576
DOC_WW_Pin1_4	910	915	PF00397	0.625
DOC_WW_Pin1_4	936	941	PF00397	0.615
DOC_WW_Pin1_4	96	101	PF00397	0.566
LIG_14-3-3_CanoR_1	101	107	PF00244	0.563
LIG_14-3-3_CanoR_1	37	43	PF00244	0.630
LIG_14-3-3_CanoR_1	53	57	PF00244	0.467
LIG_14-3-3_CanoR_1	73	78	PF00244	0.444
LIG_14-3-3_CanoR_1	87	91	PF00244	0.486
LIG_14-3-3_CanoR_1	947	953	PF00244	0.486
LIG_BIR_II_1	1	5	PF00653	0.553
LIG_BRCT_BRCA1_1	145	149	PF00533	0.465
LIG_BRCT_BRCA1_1	290	294	PF00533	0.546
LIG_BRCT_BRCA1_1	445	449	PF00533	0.527
LIG_BRCT_BRCA1_1	488	492	PF00533	0.602
LIG_BRCT_BRCA1_1	614	618	PF00533	0.575
LIG_BRCT_BRCA1_1	697	701	PF00533	0.571
LIG_BRCT_BRCA1_1	718	722	PF00533	0.598
LIG_BRCT_BRCA1_1	736	740	PF00533	0.436
LIG_BRCT_BRCA1_1	769	773	PF00533	0.594
LIG_BRCT_BRCA1_1	865	869	PF00533	0.611
LIG_BRCT_BRCA1_1	938	942	PF00533	0.619
LIG_EH_1	392	396	PF12763	0.608
LIG_EH_1	406	410	PF12763	0.518
LIG_EH_1	544	548	PF12763	0.616
LIG_EVH1_1	395	399	PF00568	0.505
LIG_FHA_1	165	171	PF00498	0.445
LIG_FHA_1	339	345	PF00498	0.504
LIG_FHA_1	347	353	PF00498	0.485
LIG_FHA_1	470	476	PF00498	0.558
LIG_FHA_1	960	966	PF00498	0.609
LIG_FHA_2	103	109	PF00498	0.525
LIG_FHA_2	119	125	PF00498	0.573
LIG_FHA_2	370	376	PF00498	0.587
LIG_FHA_2	426	432	PF00498	0.507
LIG_IRF3_LxIS_1	224	230	PF10401	0.323
LIG_LIR_Apic_2	390	394	PF02991	0.593
LIG_LIR_Apic_2	737	743	PF02991	0.538
LIG_LIR_Gen_1	197	206	PF02991	0.593
LIG_LIR_Gen_1	248	256	PF02991	0.316
LIG_LIR_Gen_1	489	498	PF02991	0.567
LIG_LIR_Nem_3	11	16	PF02991	0.555
LIG_LIR_Nem_3	197	202	PF02991	0.594
LIG_LIR_Nem_3	248	252	PF02991	0.328
LIG_LIR_Nem_3	446	452	PF02991	0.504
LIG_LIR_Nem_3	489	495	PF02991	0.566
LIG_LIR_Nem_3	615	621	PF02991	0.573
LIG_PCNA_yPIPBox_3	153	166	PF02747	0.439
LIG_Pex14_2	391	395	PF04695	0.601
LIG_Pex14_2	740	744	PF04695	0.546
LIG_SH2_CRK	199	203	PF00017	0.457
LIG_SH2_NCK_1	199	203	PF00017	0.447
LIG_SH2_STAP1	199	203	PF00017	0.447
LIG_SH3_3	278	284	PF00018	0.568
LIG_SH3_3	28	34	PF00018	0.653
LIG_SH3_3	383	389	PF00018	0.502
LIG_SH3_3	393	399	PF00018	0.478
LIG_SH3_3	495	501	PF00018	0.568
LIG_SH3_3	543	549	PF00018	0.615
LIG_SH3_3	618	624	PF00018	0.617
LIG_SH3_3	793	799	PF00018	0.583
LIG_SH3_3	94	100	PF00018	0.519
LIG_SUMO_SIM_anti_2	102	111	PF11976	0.610
MOD_CDK_SPK_2	382	387	PF00069	0.506
MOD_CDK_SPK_2	553	558	PF00069	0.550
MOD_CDK_SPK_2	96	101	PF00069	0.546
MOD_CDK_SPxxK_3	96	103	PF00069	0.548
MOD_CK1_1	115	121	PF00069	0.475
MOD_CK1_1	201	207	PF00069	0.433
MOD_CK1_1	261	267	PF00069	0.499
MOD_CK1_1	273	279	PF00069	0.564
MOD_CK1_1	289	295	PF00069	0.450
MOD_CK1_1	307	313	PF00069	0.421
MOD_CK1_1	322	328	PF00069	0.483
MOD_CK1_1	36	42	PF00069	0.502
MOD_CK1_1	380	386	PF00069	0.619
MOD_CK1_1	4	10	PF00069	0.536
MOD_CK1_1	436	442	PF00069	0.582
MOD_CK1_1	48	54	PF00069	0.563
MOD_CK1_1	507	513	PF00069	0.593
MOD_CK1_1	526	532	PF00069	0.443
MOD_CK1_1	580	586	PF00069	0.615
MOD_CK1_1	596	602	PF00069	0.487
MOD_CK1_1	610	616	PF00069	0.515
MOD_CK1_1	642	648	PF00069	0.603
MOD_CK1_1	665	671	PF00069	0.603
MOD_CK1_1	674	680	PF00069	0.532
MOD_CK1_1	692	698	PF00069	0.457
MOD_CK1_1	703	709	PF00069	0.577
MOD_CK1_1	735	741	PF00069	0.565
MOD_CK1_1	833	839	PF00069	0.616
MOD_CK1_1	863	869	PF00069	0.611
MOD_CK1_1	871	877	PF00069	0.521
MOD_CK1_1	959	965	PF00069	0.614
MOD_CK1_1	967	973	PF00069	0.547
MOD_CK1_1	99	105	PF00069	0.620
MOD_CK2_1	102	108	PF00069	0.518
MOD_CK2_1	191	197	PF00069	0.472
MOD_CK2_1	215	221	PF00069	0.446
MOD_CK2_1	227	233	PF00069	0.337
MOD_CK2_1	247	253	PF00069	0.248
MOD_CK2_1	348	354	PF00069	0.494
MOD_CK2_1	369	375	PF00069	0.589
MOD_DYRK1A_RPxSP_1	96	100	PF00069	0.543
MOD_GlcNHglycan	183	187	PF01048	0.376
MOD_GlcNHglycan	210	213	PF01048	0.407
MOD_GlcNHglycan	309	312	PF01048	0.543
MOD_GlcNHglycan	314	317	PF01048	0.542
MOD_GlcNHglycan	326	329	PF01048	0.470
MOD_GlcNHglycan	38	41	PF01048	0.591
MOD_GlcNHglycan	380	383	PF01048	0.564
MOD_GlcNHglycan	404	407	PF01048	0.533
MOD_GlcNHglycan	413	416	PF01048	0.531
MOD_GlcNHglycan	435	438	PF01048	0.581
MOD_GlcNHglycan	453	456	PF01048	0.489
MOD_GlcNHglycan	484	487	PF01048	0.541
MOD_GlcNHglycan	506	509	PF01048	0.629
MOD_GlcNHglycan	523	526	PF01048	0.452
MOD_GlcNHglycan	531	534	PF01048	0.500
MOD_GlcNHglycan	539	542	PF01048	0.462
MOD_GlcNHglycan	559	562	PF01048	0.479
MOD_GlcNHglycan	579	582	PF01048	0.585
MOD_GlcNHglycan	598	601	PF01048	0.461
MOD_GlcNHglycan	604	607	PF01048	0.595
MOD_GlcNHglycan	609	612	PF01048	0.539
MOD_GlcNHglycan	614	617	PF01048	0.453
MOD_GlcNHglycan	630	633	PF01048	0.471
MOD_GlcNHglycan	659	662	PF01048	0.549
MOD_GlcNHglycan	673	676	PF01048	0.531
MOD_GlcNHglycan	678	681	PF01048	0.474
MOD_GlcNHglycan	682	685	PF01048	0.541
MOD_GlcNHglycan	691	694	PF01048	0.458
MOD_GlcNHglycan	730	733	PF01048	0.547
MOD_GlcNHglycan	734	737	PF01048	0.510
MOD_GlcNHglycan	740	743	PF01048	0.509
MOD_GlcNHglycan	748	751	PF01048	0.467
MOD_GlcNHglycan	753	756	PF01048	0.452
MOD_GlcNHglycan	820	823	PF01048	0.562
MOD_GlcNHglycan	832	835	PF01048	0.530
MOD_GlcNHglycan	850	853	PF01048	0.466
MOD_GlcNHglycan	862	865	PF01048	0.499
MOD_GlcNHglycan	884	887	PF01048	0.599
MOD_GSK3_1	114	121	PF00069	0.669
MOD_GSK3_1	143	150	PF00069	0.464
MOD_GSK3_1	204	211	PF00069	0.399
MOD_GSK3_1	234	241	PF00069	0.434
MOD_GSK3_1	270	277	PF00069	0.578
MOD_GSK3_1	303	310	PF00069	0.577
MOD_GSK3_1	318	325	PF00069	0.481
MOD_GSK3_1	326	333	PF00069	0.531
MOD_GSK3_1	369	376	PF00069	0.613
MOD_GSK3_1	377	384	PF00069	0.572
MOD_GSK3_1	407	414	PF00069	0.530
MOD_GSK3_1	427	434	PF00069	0.447
MOD_GSK3_1	48	55	PF00069	0.651
MOD_GSK3_1	482	489	PF00069	0.594
MOD_GSK3_1	503	510	PF00069	0.559
MOD_GSK3_1	517	524	PF00069	0.463
MOD_GSK3_1	529	536	PF00069	0.508
MOD_GSK3_1	548	555	PF00069	0.447
MOD_GSK3_1	56	63	PF00069	0.558
MOD_GSK3_1	576	583	PF00069	0.615
MOD_GSK3_1	584	591	PF00069	0.557
MOD_GSK3_1	602	609	PF00069	0.499
MOD_GSK3_1	623	630	PF00069	0.588
MOD_GSK3_1	639	646	PF00069	0.464
MOD_GSK3_1	662	669	PF00069	0.603
MOD_GSK3_1	674	681	PF00069	0.503
MOD_GSK3_1	685	692	PF00069	0.502
MOD_GSK3_1	696	703	PF00069	0.566
MOD_GSK3_1	717	724	PF00069	0.562
MOD_GSK3_1	728	735	PF00069	0.496
MOD_GSK3_1	753	760	PF00069	0.547
MOD_GSK3_1	826	833	PF00069	0.511
MOD_GSK3_1	838	845	PF00069	0.511
MOD_GSK3_1	878	885	PF00069	0.492
MOD_GSK3_1	955	962	PF00069	0.612
MOD_LATS_1	371	377	PF00433	0.506
MOD_N-GLC_1	191	196	PF02516	0.391
MOD_N-GLC_1	377	382	PF02516	0.563
MOD_N-GLC_1	45	50	PF02516	0.616
MOD_N-GLC_1	607	612	PF02516	0.534
MOD_N-GLC_1	651	656	PF02516	0.556
MOD_N-GLC_1	695	700	PF02516	0.583
MOD_N-GLC_1	860	865	PF02516	0.612
MOD_N-GLC_2	299	301	PF02516	0.541
MOD_NEK2_1	1	6	PF00069	0.600
MOD_NEK2_1	165	170	PF00069	0.451
MOD_NEK2_1	191	196	PF00069	0.461
MOD_NEK2_1	206	211	PF00069	0.467
MOD_NEK2_1	227	232	PF00069	0.446
MOD_NEK2_1	304	309	PF00069	0.455
MOD_NEK2_1	337	342	PF00069	0.579
MOD_NEK2_1	411	416	PF00069	0.606
MOD_NEK2_1	528	533	PF00069	0.572
MOD_NEK2_1	593	598	PF00069	0.608
MOD_NEK2_1	643	648	PF00069	0.603
MOD_NEK2_1	685	690	PF00069	0.515
MOD_NEK2_1	701	706	PF00069	0.526
MOD_NEK2_1	717	722	PF00069	0.495
MOD_NEK2_1	728	733	PF00069	0.498
MOD_NEK2_1	818	823	PF00069	0.532
MOD_NEK2_1	848	853	PF00069	0.583
MOD_NEK2_1	882	887	PF00069	0.564
MOD_NEK2_1	955	960	PF00069	0.565
MOD_NEK2_1	965	970	PF00069	0.580
MOD_NEK2_2	878	883	PF00069	0.574
MOD_NEK2_2	920	925	PF00069	0.501
MOD_PIKK_1	1	7	PF00454	0.549
MOD_PIKK_1	930	936	PF00454	0.584
MOD_PIKK_1	956	962	PF00454	0.568
MOD_PK_1	198	204	PF00069	0.389
MOD_PKA_2	102	108	PF00069	0.573
MOD_PKA_2	238	244	PF00069	0.478
MOD_PKA_2	36	42	PF00069	0.609
MOD_PKA_2	52	58	PF00069	0.498
MOD_PKA_2	86	92	PF00069	0.477
MOD_PKB_1	135	143	PF00069	0.402
MOD_PKB_1	71	79	PF00069	0.513
MOD_Plk_1	115	121	PF00069	0.743
MOD_Plk_1	191	197	PF00069	0.451
MOD_Plk_1	215	221	PF00069	0.504
MOD_Plk_1	51	57	PF00069	0.553
MOD_Plk_4	102	108	PF00069	0.673
MOD_Plk_4	198	204	PF00069	0.455
MOD_Plk_4	238	244	PF00069	0.425
MOD_Plk_4	462	468	PF00069	0.541
MOD_Plk_4	56	62	PF00069	0.653
MOD_Plk_4	768	774	PF00069	0.524
MOD_Plk_4	843	849	PF00069	0.626
MOD_Plk_4	878	884	PF00069	0.598
MOD_Plk_4	960	966	PF00069	0.615
MOD_ProDKin_1	261	267	PF00069	0.518
MOD_ProDKin_1	270	276	PF00069	0.575
MOD_ProDKin_1	277	283	PF00069	0.517
MOD_ProDKin_1	322	328	PF00069	0.609
MOD_ProDKin_1	382	388	PF00069	0.565
MOD_ProDKin_1	394	400	PF00069	0.585
MOD_ProDKin_1	497	503	PF00069	0.567
MOD_ProDKin_1	523	529	PF00069	0.580
MOD_ProDKin_1	533	539	PF00069	0.495
MOD_ProDKin_1	553	559	PF00069	0.532
MOD_ProDKin_1	564	570	PF00069	0.529
MOD_ProDKin_1	625	631	PF00069	0.609
MOD_ProDKin_1	651	657	PF00069	0.562
MOD_ProDKin_1	696	702	PF00069	0.521
MOD_ProDKin_1	735	741	PF00069	0.576
MOD_ProDKin_1	910	916	PF00069	0.624
MOD_ProDKin_1	936	942	PF00069	0.616
MOD_ProDKin_1	96	102	PF00069	0.567
MOD_SUMO_for_1	186	189	PF00179	0.428
MOD_SUMO_rev_2	230	237	PF00179	0.440
TRG_DiLeu_BaEn_4	215	221	PF01217	0.446
TRG_ENDOCYTIC_2	199	202	PF00928	0.456
TRG_ENDOCYTIC_2	203	206	PF00928	0.422
TRG_ER_diArg_1	100	103	PF00400	0.581
TRG_ER_diArg_1	134	137	PF00400	0.533
TRG_ER_diArg_1	29	32	PF00400	0.599
TRG_ER_diArg_1	66	69	PF00400	0.608
TRG_ER_diArg_1	70	73	PF00400	0.594
TRG_ER_diArg_1	95	97	PF00400	0.595
TRG_ER_diArg_1	975	977	PF00400	0.605
TRG_NES_CRM1_1	183	197	PF08389	0.444
TRG_NLS_MonoExtC_3	970	975	PF00514	0.607
TRG_Pf-PMV_PEXEL_1	88	93	PF00026	0.548

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X4C6	Leishmania donovani	99%	100%
A4HJ89	Leishmania braziliensis	65%	98%
E9B1Q5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	99%
Q4Q6F5	Leishmania major	86%	99%