Alba domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I6M3_LEIIN

TriTrypDb:

LINF_310016000

Length:

419

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I6M3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6M3

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	3
GO:0003677	DNA binding	4	3
GO:0005488	binding	1	3
GO:0097159	organic cyclic compound binding	2	3
GO:1901363	heterocyclic compound binding	2	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	254	258	PF00656	0.514
CLV_C14_Caspase3-7	411	415	PF00656	0.734
CLV_NRD_NRD_1	164	166	PF00675	0.651
CLV_NRD_NRD_1	196	198	PF00675	0.709
CLV_NRD_NRD_1	278	280	PF00675	0.668
CLV_NRD_NRD_1	333	335	PF00675	0.737
CLV_NRD_NRD_1	360	362	PF00675	0.639
CLV_NRD_NRD_1	378	380	PF00675	0.781
CLV_NRD_NRD_1	382	384	PF00675	0.699
CLV_PCSK_FUR_1	276	280	PF00082	0.664
CLV_PCSK_FUR_1	331	335	PF00082	0.824
CLV_PCSK_FUR_1	357	361	PF00082	0.741
CLV_PCSK_KEX2_1	162	164	PF00082	0.675
CLV_PCSK_KEX2_1	192	194	PF00082	0.699
CLV_PCSK_KEX2_1	196	198	PF00082	0.704
CLV_PCSK_KEX2_1	211	213	PF00082	0.687
CLV_PCSK_KEX2_1	278	280	PF00082	0.658
CLV_PCSK_KEX2_1	282	284	PF00082	0.644
CLV_PCSK_KEX2_1	331	333	PF00082	0.753
CLV_PCSK_KEX2_1	356	358	PF00082	0.730
CLV_PCSK_KEX2_1	359	361	PF00082	0.701
CLV_PCSK_KEX2_1	378	380	PF00082	0.590
CLV_PCSK_PC1ET2_1	162	164	PF00082	0.719
CLV_PCSK_PC1ET2_1	192	194	PF00082	0.699
CLV_PCSK_PC1ET2_1	211	213	PF00082	0.687
CLV_PCSK_PC1ET2_1	282	284	PF00082	0.716
CLV_PCSK_PC1ET2_1	356	358	PF00082	0.730
CLV_PCSK_PC7_1	158	164	PF00082	0.748
CLV_PCSK_PC7_1	274	280	PF00082	0.818
CLV_PCSK_SKI1_1	115	119	PF00082	0.588
CLV_PCSK_SKI1_1	223	227	PF00082	0.780
CLV_PCSK_SKI1_1	283	287	PF00082	0.711
CLV_PCSK_SKI1_1	336	340	PF00082	0.751
CLV_PCSK_SKI1_1	84	88	PF00082	0.637
DEG_Nend_Nbox_1	1	3	PF02207	0.640
DEG_SPOP_SBC_1	183	187	PF00917	0.683
DEG_SPOP_SBC_1	93	97	PF00917	0.654
DOC_CYCLIN_RxL_1	111	120	PF00134	0.587
DOC_MAPK_gen_1	192	203	PF00069	0.724
DOC_MAPK_gen_1	381	391	PF00069	0.690
DOC_MAPK_gen_1	91	100	PF00069	0.556
DOC_USP7_MATH_1	174	178	PF00917	0.585
DOC_USP7_MATH_1	206	210	PF00917	0.748
DOC_USP7_MATH_1	248	252	PF00917	0.569
DOC_USP7_MATH_1	398	402	PF00917	0.745
DOC_USP7_MATH_1	407	411	PF00917	0.738
DOC_USP7_MATH_1	82	86	PF00917	0.522
DOC_USP7_MATH_1	93	97	PF00917	0.621
DOC_USP7_UBL2_3	162	166	PF12436	0.730
DOC_USP7_UBL2_3	188	192	PF12436	0.761
DOC_USP7_UBL2_3	207	211	PF12436	0.537
DOC_WW_Pin1_4	133	138	PF00397	0.680
DOC_WW_Pin1_4	156	161	PF00397	0.759
DOC_WW_Pin1_4	21	26	PF00397	0.541
DOC_WW_Pin1_4	308	313	PF00397	0.777
LIG_14-3-3_CanoR_1	12	19	PF00244	0.542
LIG_14-3-3_CanoR_1	199	204	PF00244	0.720
LIG_14-3-3_CanoR_1	223	232	PF00244	0.645
LIG_14-3-3_CanoR_1	276	286	PF00244	0.781
LIG_14-3-3_CanoR_1	44	53	PF00244	0.491
LIG_14-3-3_CanoR_1	70	77	PF00244	0.524
LIG_14-3-3_CanoR_1	94	99	PF00244	0.570
LIG_Actin_WH2_2	69	86	PF00022	0.588
LIG_BRCT_BRCA1_1	363	367	PF00533	0.707
LIG_BRCT_BRCA1_1	47	51	PF00533	0.632
LIG_CAP-Gly_1	414	419	PF01302	0.729
LIG_FHA_1	170	176	PF00498	0.718
LIG_FHA_1	37	43	PF00498	0.508
LIG_FHA_1	93	99	PF00498	0.588
LIG_FHA_2	143	149	PF00498	0.768
LIG_FHA_2	224	230	PF00498	0.816
LIG_FHA_2	279	285	PF00498	0.684
LIG_FHA_2	297	303	PF00498	0.708
LIG_FHA_2	309	315	PF00498	0.613
LIG_FHA_2	345	351	PF00498	0.704
LIG_LIR_Gen_1	54	64	PF02991	0.572
LIG_LIR_Nem_3	301	307	PF02991	0.572
LIG_LIR_Nem_3	54	60	PF02991	0.623
LIG_PDZ_Class_2	414	419	PF00595	0.807
LIG_Rb_pABgroove_1	112	120	PF01858	0.547
LIG_SH2_NCK_1	307	311	PF00017	0.587
LIG_SH2_SRC	307	310	PF00017	0.586
LIG_SH2_STAP1	9	13	PF00017	0.476
LIG_SH3_1	266	272	PF00018	0.721
LIG_SH3_2	269	274	PF14604	0.814
LIG_SH3_3	134	140	PF00018	0.697
LIG_SH3_3	164	170	PF00018	0.734
LIG_SH3_3	188	194	PF00018	0.592
LIG_SH3_3	266	272	PF00018	0.799
LIG_SH3_4	405	412	PF00018	0.700
MOD_CDK_SPK_2	156	161	PF00069	0.653
MOD_CDK_SPxK_1	156	162	PF00069	0.654
MOD_CDK_SPxxK_3	156	163	PF00069	0.654
MOD_CK1_1	21	27	PF00069	0.771
MOD_CK1_1	227	233	PF00069	0.753
MOD_CK1_1	34	40	PF00069	0.498
MOD_CK2_1	14	20	PF00069	0.531
MOD_CK2_1	142	148	PF00069	0.809
MOD_CK2_1	223	229	PF00069	0.655
MOD_CK2_1	278	284	PF00069	0.690
MOD_CK2_1	308	314	PF00069	0.688
MOD_CK2_1	344	350	PF00069	0.747
MOD_CK2_1	398	404	PF00069	0.718
MOD_Cter_Amidation	163	166	PF01082	0.692
MOD_Cter_Amidation	194	197	PF01082	0.685
MOD_Cter_Amidation	276	279	PF01082	0.782
MOD_Cter_Amidation	357	360	PF01082	0.703
MOD_Cter_Amidation	376	379	PF01082	0.606
MOD_GlcNHglycan	119	122	PF01048	0.606
MOD_GlcNHglycan	130	133	PF01048	0.510
MOD_GlcNHglycan	14	17	PF01048	0.556
MOD_GlcNHglycan	215	218	PF01048	0.799
MOD_GlcNHglycan	219	222	PF01048	0.743
MOD_GlcNHglycan	238	241	PF01048	0.672
MOD_GlcNHglycan	248	251	PF01048	0.591
MOD_GlcNHglycan	375	378	PF01048	0.652
MOD_GlcNHglycan	72	75	PF01048	0.578
MOD_GlcNHglycan	79	82	PF01048	0.523
MOD_GSK3_1	14	21	PF00069	0.514
MOD_GSK3_1	213	220	PF00069	0.801
MOD_GSK3_1	223	230	PF00069	0.650
MOD_GSK3_1	344	351	PF00069	0.747
MOD_GSK3_1	94	101	PF00069	0.646
MOD_NEK2_1	117	122	PF00069	0.564
MOD_NEK2_1	18	23	PF00069	0.568
MOD_NEK2_1	2	7	PF00069	0.650
MOD_NEK2_1	213	218	PF00069	0.683
MOD_NEK2_1	392	397	PF00069	0.820
MOD_NEK2_1	76	81	PF00069	0.585
MOD_NEK2_2	260	265	PF00069	0.585
MOD_NEK2_2	36	41	PF00069	0.606
MOD_PIKK_1	392	398	PF00454	0.820
MOD_PK_1	94	100	PF00069	0.568
MOD_PKA_1	278	284	PF00069	0.674
MOD_PKA_1	373	379	PF00069	0.689
MOD_PKA_2	107	113	PF00069	0.556
MOD_PKA_2	213	219	PF00069	0.721
MOD_PKA_2	277	283	PF00069	0.684
MOD_PKA_2	291	297	PF00069	0.565
MOD_PKA_2	93	99	PF00069	0.637
MOD_PKB_1	197	205	PF00069	0.719
MOD_PKB_1	276	284	PF00069	0.709
MOD_PKB_1	359	367	PF00069	0.726
MOD_Plk_1	234	240	PF00069	0.684
MOD_Plk_2-3	344	350	PF00069	0.747
MOD_Plk_4	14	20	PF00069	0.531
MOD_Plk_4	82	88	PF00069	0.521
MOD_ProDKin_1	133	139	PF00069	0.684
MOD_ProDKin_1	156	162	PF00069	0.760
MOD_ProDKin_1	21	27	PF00069	0.549
MOD_ProDKin_1	308	314	PF00069	0.782
TRG_ER_diArg_1	196	199	PF00400	0.710
TRG_ER_diArg_1	212	215	PF00400	0.746
TRG_ER_diArg_1	273	276	PF00400	0.678
TRG_ER_diArg_1	331	334	PF00400	0.752
TRG_ER_diArg_1	357	360	PF00400	0.740
TRG_ER_diArg_1	378	381	PF00400	0.821
TRG_NLS_Bipartite_1	192	214	PF00514	0.793
TRG_NLS_MonoCore_2	164	169	PF00514	0.680
TRG_NLS_MonoCore_2	203	208	PF00514	0.569
TRG_NLS_MonoExtC_3	160	165	PF00514	0.704
TRG_NLS_MonoExtC_3	209	214	PF00514	0.765
TRG_NLS_MonoExtC_3	355	360	PF00514	0.701
TRG_NLS_MonoExtN_4	158	165	PF00514	0.706
TRG_NLS_MonoExtN_4	207	214	PF00514	0.769
TRG_Pf-PMV_PEXEL_1	115	119	PF00026	0.609

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIK0	Leptomonas seymouri	35%	100%
A0A3S7X4A5	Leishmania donovani	99%	100%
A4HJ79	Leishmania braziliensis	59%	100%
E9B1P6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
Q4Q6G4	Leishmania major	84%	97%