Proteophosphoglycan 5, related protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I6L0_LEIIN

TriTrypDb:

LINF_310010700

Length:

678

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I6L0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6L0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	135	139	PF00656	0.666
CLV_C14_Caspase3-7	379	383	PF00656	0.650
CLV_C14_Caspase3-7	670	674	PF00656	0.649
CLV_NRD_NRD_1	215	217	PF00675	0.658
CLV_NRD_NRD_1	472	474	PF00675	0.813
CLV_NRD_NRD_1	640	642	PF00675	0.661
CLV_PCSK_FUR_1	638	642	PF00082	0.664
CLV_PCSK_KEX2_1	215	217	PF00082	0.658
CLV_PCSK_KEX2_1	339	341	PF00082	0.582
CLV_PCSK_KEX2_1	472	474	PF00082	0.807
CLV_PCSK_KEX2_1	640	642	PF00082	0.661
CLV_PCSK_PC1ET2_1	339	341	PF00082	0.582
CLV_PCSK_SKI1_1	192	196	PF00082	0.637
CLV_PCSK_SKI1_1	333	337	PF00082	0.705
DEG_APCC_DBOX_1	535	543	PF00400	0.624
DEG_Nend_UBRbox_2	1	3	PF02207	0.602
DEG_SPOP_SBC_1	271	275	PF00917	0.591
DEG_SPOP_SBC_1	280	284	PF00917	0.553
DEG_SPOP_SBC_1	325	329	PF00917	0.641
DEG_SPOP_SBC_1	492	496	PF00917	0.689
DEG_SPOP_SBC_1	510	514	PF00917	0.502
DOC_CKS1_1	225	230	PF01111	0.657
DOC_CKS1_1	462	467	PF01111	0.682
DOC_CYCLIN_yCln2_LP_2	137	143	PF00134	0.683
DOC_MAPK_gen_1	652	660	PF00069	0.593
DOC_MAPK_MEF2A_6	653	662	PF00069	0.644
DOC_PIKK_1	128	136	PF02985	0.641
DOC_PP2B_LxvP_1	150	153	PF13499	0.579
DOC_PP2B_LxvP_1	439	442	PF13499	0.596
DOC_PP2B_LxvP_1	508	511	PF13499	0.649
DOC_PP2B_LxvP_1	549	552	PF13499	0.584
DOC_PP4_FxxP_1	15	18	PF00568	0.658
DOC_PP4_FxxP_1	22	25	PF00568	0.593
DOC_PP4_FxxP_1	222	225	PF00568	0.575
DOC_PP4_FxxP_1	648	651	PF00568	0.617
DOC_PP4_MxPP_1	1	4	PF00568	0.646
DOC_USP7_MATH_1	190	194	PF00917	0.681
DOC_USP7_MATH_1	235	239	PF00917	0.679
DOC_USP7_MATH_1	245	249	PF00917	0.628
DOC_USP7_MATH_1	272	276	PF00917	0.656
DOC_USP7_MATH_1	280	284	PF00917	0.591
DOC_USP7_MATH_1	30	34	PF00917	0.662
DOC_USP7_MATH_1	325	329	PF00917	0.695
DOC_USP7_MATH_1	403	407	PF00917	0.695
DOC_USP7_MATH_1	420	424	PF00917	0.661
DOC_USP7_MATH_1	425	429	PF00917	0.613
DOC_USP7_MATH_1	440	444	PF00917	0.517
DOC_USP7_MATH_1	457	461	PF00917	0.647
DOC_USP7_MATH_1	480	484	PF00917	0.600
DOC_USP7_MATH_1	527	531	PF00917	0.610
DOC_USP7_MATH_1	552	556	PF00917	0.624
DOC_USP7_MATH_1	626	630	PF00917	0.593
DOC_WW_Pin1_4	201	206	PF00397	0.660
DOC_WW_Pin1_4	221	226	PF00397	0.503
DOC_WW_Pin1_4	26	31	PF00397	0.688
DOC_WW_Pin1_4	263	268	PF00397	0.643
DOC_WW_Pin1_4	35	40	PF00397	0.673
DOC_WW_Pin1_4	384	389	PF00397	0.674
DOC_WW_Pin1_4	399	404	PF00397	0.584
DOC_WW_Pin1_4	45	50	PF00397	0.630
DOC_WW_Pin1_4	455	460	PF00397	0.720
DOC_WW_Pin1_4	461	466	PF00397	0.667
DOC_WW_Pin1_4	476	481	PF00397	0.614
DOC_WW_Pin1_4	495	500	PF00397	0.556
DOC_WW_Pin1_4	503	508	PF00397	0.692
DOC_WW_Pin1_4	534	539	PF00397	0.598
DOC_WW_Pin1_4	564	569	PF00397	0.697
DOC_WW_Pin1_4	571	576	PF00397	0.659
DOC_WW_Pin1_4	76	81	PF00397	0.738
DOC_WW_Pin1_4	91	96	PF00397	0.520
LIG_14-3-3_CanoR_1	186	190	PF00244	0.610
LIG_14-3-3_CanoR_1	472	482	PF00244	0.706
LIG_14-3-3_CanoR_1	594	600	PF00244	0.660
LIG_14-3-3_CanoR_1	640	644	PF00244	0.664
LIG_14-3-3_CanoR_1	668	673	PF00244	0.558
LIG_14-3-3_CanoR_1	84	93	PF00244	0.648
LIG_APCC_ABBA_1	389	394	PF00400	0.688
LIG_BRCT_BRCA1_1	18	22	PF00533	0.617
LIG_BRCT_BRCA1_1	432	436	PF00533	0.678
LIG_CSL_BTD_1	92	95	PF09270	0.678
LIG_CtBP_PxDLS_1	502	506	PF00389	0.567
LIG_EVH1_2	311	315	PF00568	0.573
LIG_FHA_1	114	120	PF00498	0.703
LIG_FHA_1	266	272	PF00498	0.602
LIG_FHA_1	292	298	PF00498	0.701
LIG_FHA_1	510	516	PF00498	0.587
LIG_FHA_1	523	529	PF00498	0.634
LIG_FHA_1	55	61	PF00498	0.652
LIG_FHA_1	6	12	PF00498	0.711
LIG_FHA_1	63	69	PF00498	0.672
LIG_FHA_2	162	168	PF00498	0.677
LIG_LIR_Apic_2	13	18	PF02991	0.661
LIG_LIR_Apic_2	19	25	PF02991	0.598
LIG_LIR_Nem_3	346	350	PF02991	0.702
LIG_LIR_Nem_3	433	439	PF02991	0.628
LIG_Pex14_2	55	59	PF04695	0.624
LIG_SH3_2	264	269	PF14604	0.626
LIG_SH3_2	373	378	PF14604	0.664
LIG_SH3_3	150	156	PF00018	0.630
LIG_SH3_3	222	228	PF00018	0.651
LIG_SH3_3	261	267	PF00018	0.658
LIG_SH3_3	274	280	PF00018	0.575
LIG_SH3_3	294	300	PF00018	0.764
LIG_SH3_3	370	376	PF00018	0.686
LIG_SH3_3	397	403	PF00018	0.697
LIG_SH3_3	496	502	PF00018	0.746
LIG_SH3_3	504	510	PF00018	0.671
LIG_SH3_3	532	538	PF00018	0.621
LIG_SH3_3	562	568	PF00018	0.663
LIG_SH3_3	65	71	PF00018	0.715
LIG_SUMO_SIM_anti_2	445	451	PF11976	0.638
LIG_SUMO_SIM_par_1	173	180	PF11976	0.633
LIG_SUMO_SIM_par_1	501	506	PF11976	0.617
LIG_TRAF2_1	163	166	PF00917	0.736
LIG_TRAF2_1	450	453	PF00917	0.709
LIG_UBA3_1	643	652	PF00899	0.631
LIG_WRC_WIRS_1	178	183	PF05994	0.592
LIG_WRC_WIRS_1	344	349	PF05994	0.698
LIG_WRC_WIRS_1	52	57	PF05994	0.651
LIG_WW_3	311	315	PF00397	0.660
MOD_CDC14_SPxK_1	266	269	PF00782	0.660
MOD_CDC14_SPxK_1	48	51	PF00782	0.715
MOD_CDK_SPK_2	476	481	PF00069	0.717
MOD_CDK_SPxK_1	263	269	PF00069	0.648
MOD_CDK_SPxK_1	45	51	PF00069	0.716
MOD_CK1_1	120	126	PF00069	0.711
MOD_CK1_1	204	210	PF00069	0.701
MOD_CK1_1	224	230	PF00069	0.609
MOD_CK1_1	287	293	PF00069	0.611
MOD_CK1_1	328	334	PF00069	0.718
MOD_CK1_1	33	39	PF00069	0.678
MOD_CK1_1	353	359	PF00069	0.754
MOD_CK1_1	380	386	PF00069	0.678
MOD_CK1_1	45	51	PF00069	0.639
MOD_CK1_1	458	464	PF00069	0.676
MOD_CK1_1	476	482	PF00069	0.570
MOD_CK1_1	483	489	PF00069	0.646
MOD_CK1_1	54	60	PF00069	0.609
MOD_CK1_1	555	561	PF00069	0.720
MOD_CK1_1	606	612	PF00069	0.728
MOD_CK1_1	613	619	PF00069	0.685
MOD_CK1_1	62	68	PF00069	0.575
MOD_CK1_1	667	673	PF00069	0.721
MOD_CK1_1	91	97	PF00069	0.632
MOD_CK2_1	109	115	PF00069	0.691
MOD_CK2_1	122	128	PF00069	0.526
MOD_CK2_1	159	165	PF00069	0.678
MOD_CK2_1	447	453	PF00069	0.715
MOD_CK2_1	534	540	PF00069	0.637
MOD_DYRK1A_RPxSP_1	399	403	PF00069	0.653
MOD_GlcNHglycan	143	146	PF01048	0.637
MOD_GlcNHglycan	161	164	PF01048	0.528
MOD_GlcNHglycan	18	21	PF01048	0.673
MOD_GlcNHglycan	181	184	PF01048	0.510
MOD_GlcNHglycan	242	246	PF01048	0.705
MOD_GlcNHglycan	247	250	PF01048	0.641
MOD_GlcNHglycan	251	254	PF01048	0.595
MOD_GlcNHglycan	32	35	PF01048	0.652
MOD_GlcNHglycan	382	386	PF01048	0.699
MOD_GlcNHglycan	417	421	PF01048	0.607
MOD_GlcNHglycan	431	435	PF01048	0.554
MOD_GlcNHglycan	442	445	PF01048	0.606
MOD_GlcNHglycan	495	498	PF01048	0.742
MOD_GlcNHglycan	557	560	PF01048	0.713
MOD_GlcNHglycan	616	619	PF01048	0.701
MOD_GlcNHglycan	62	65	PF01048	0.764
MOD_GlcNHglycan	628	631	PF01048	0.588
MOD_GSK3_1	109	116	PF00069	0.697
MOD_GSK3_1	170	177	PF00069	0.659
MOD_GSK3_1	200	207	PF00069	0.698
MOD_GSK3_1	241	248	PF00069	0.693
MOD_GSK3_1	26	33	PF00069	0.711
MOD_GSK3_1	280	287	PF00069	0.681
MOD_GSK3_1	324	331	PF00069	0.692
MOD_GSK3_1	35	42	PF00069	0.715
MOD_GSK3_1	350	357	PF00069	0.749
MOD_GSK3_1	377	384	PF00069	0.659
MOD_GSK3_1	395	402	PF00069	0.675
MOD_GSK3_1	403	410	PF00069	0.708
MOD_GSK3_1	416	423	PF00069	0.645
MOD_GSK3_1	425	432	PF00069	0.540
MOD_GSK3_1	457	464	PF00069	0.701
MOD_GSK3_1	468	475	PF00069	0.652
MOD_GSK3_1	476	483	PF00069	0.593
MOD_GSK3_1	487	494	PF00069	0.637
MOD_GSK3_1	51	58	PF00069	0.546
MOD_GSK3_1	589	596	PF00069	0.668
MOD_GSK3_1	59	66	PF00069	0.615
MOD_GSK3_1	602	609	PF00069	0.594
MOD_GSK3_1	610	617	PF00069	0.643
MOD_GSK3_1	664	671	PF00069	0.742
MOD_GSK3_1	84	91	PF00069	0.791
MOD_N-GLC_1	394	399	PF02516	0.708
MOD_N-GLC_1	403	408	PF02516	0.685
MOD_N-GLC_1	473	478	PF02516	0.731
MOD_N-GLC_1	488	493	PF02516	0.546
MOD_NEK2_1	159	164	PF00069	0.652
MOD_NEK2_1	241	246	PF00069	0.659
MOD_NEK2_1	256	261	PF00069	0.572
MOD_NEK2_1	315	320	PF00069	0.657
MOD_NEK2_1	430	435	PF00069	0.697
MOD_NEK2_1	493	498	PF00069	0.647
MOD_NEK2_1	55	60	PF00069	0.690
MOD_NEK2_1	587	592	PF00069	0.823
MOD_NEK2_1	603	608	PF00069	0.495
MOD_NEK2_2	190	195	PF00069	0.632
MOD_NEK2_2	343	348	PF00069	0.620
MOD_NEK2_2	359	364	PF00069	0.533
MOD_PIKK_1	326	332	PF00454	0.611
MOD_PIKK_1	42	48	PF00454	0.724
MOD_PIKK_1	448	454	PF00454	0.658
MOD_PIKK_1	589	595	PF00454	0.645
MOD_PK_1	668	674	PF00069	0.565
MOD_PKA_1	472	478	PF00069	0.724
MOD_PKA_2	120	126	PF00069	0.733
MOD_PKA_2	16	22	PF00069	0.734
MOD_PKA_2	185	191	PF00069	0.609
MOD_PKA_2	280	286	PF00069	0.694
MOD_PKA_2	354	360	PF00069	0.656
MOD_PKA_2	377	383	PF00069	0.679
MOD_PKA_2	468	474	PF00069	0.723
MOD_PKA_2	480	486	PF00069	0.570
MOD_PKA_2	593	599	PF00069	0.639
MOD_PKA_2	639	645	PF00069	0.663
MOD_PKA_2	667	673	PF00069	0.610
MOD_Plk_1	359	365	PF00069	0.666
MOD_Plk_1	395	401	PF00069	0.750
MOD_Plk_1	416	422	PF00069	0.687
MOD_Plk_1	488	494	PF00069	0.678
MOD_Plk_1	610	616	PF00069	0.703
MOD_Plk_2-3	161	167	PF00069	0.679
MOD_Plk_4	10	16	PF00069	0.732
MOD_Plk_4	480	486	PF00069	0.650
MOD_Plk_4	55	61	PF00069	0.699
MOD_Plk_4	552	558	PF00069	0.706
MOD_Plk_4	603	609	PF00069	0.751
MOD_Plk_4	63	69	PF00069	0.628
MOD_Plk_4	658	664	PF00069	0.517
MOD_ProDKin_1	201	207	PF00069	0.663
MOD_ProDKin_1	221	227	PF00069	0.501
MOD_ProDKin_1	26	32	PF00069	0.692
MOD_ProDKin_1	263	269	PF00069	0.648
MOD_ProDKin_1	35	41	PF00069	0.674
MOD_ProDKin_1	384	390	PF00069	0.674
MOD_ProDKin_1	399	405	PF00069	0.586
MOD_ProDKin_1	45	51	PF00069	0.632
MOD_ProDKin_1	455	461	PF00069	0.721
MOD_ProDKin_1	476	482	PF00069	0.715
MOD_ProDKin_1	495	501	PF00069	0.556
MOD_ProDKin_1	503	509	PF00069	0.691
MOD_ProDKin_1	534	540	PF00069	0.637
MOD_ProDKin_1	564	570	PF00069	0.698
MOD_ProDKin_1	571	577	PF00069	0.657
MOD_ProDKin_1	76	82	PF00069	0.740
MOD_ProDKin_1	91	97	PF00069	0.522
TRG_DiLeu_BaEn_4	166	172	PF01217	0.716
TRG_ER_diArg_1	214	216	PF00400	0.659
TRG_ER_diArg_1	528	531	PF00400	0.684

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ISE9	Leishmania donovani	98%	100%
A4HJ31	Leishmania braziliensis	59%	99%
E9B1K3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4Q6L0	Leishmania major	90%	100%