LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I6G9_LEIIN
TriTrypDb:
LINF_310013300
Length:
297

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I6G9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6G9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 193 197 PF00656 0.461
CLV_NRD_NRD_1 62 64 PF00675 0.458
CLV_PCSK_SKI1_1 130 134 PF00082 0.543
CLV_PCSK_SKI1_1 150 154 PF00082 0.328
CLV_PCSK_SKI1_1 190 194 PF00082 0.546
CLV_PCSK_SKI1_1 22 26 PF00082 0.526
CLV_PCSK_SKI1_1 32 36 PF00082 0.391
DEG_APCC_DBOX_1 100 108 PF00400 0.363
DOC_CKS1_1 253 258 PF01111 0.561
DOC_PP2B_LxvP_1 218 221 PF13499 0.502
DOC_PP2B_LxvP_1 233 236 PF13499 0.493
DOC_PP4_MxPP_1 224 227 PF00568 0.598
DOC_USP7_MATH_1 201 205 PF00917 0.448
DOC_USP7_MATH_1 239 243 PF00917 0.643
DOC_USP7_MATH_1 271 275 PF00917 0.582
DOC_USP7_UBL2_3 130 134 PF12436 0.567
DOC_USP7_UBL2_3 146 150 PF12436 0.520
DOC_USP7_UBL2_3 153 157 PF12436 0.437
DOC_WW_Pin1_4 137 142 PF00397 0.477
DOC_WW_Pin1_4 252 257 PF00397 0.709
DOC_WW_Pin1_4 4 9 PF00397 0.377
DOC_WW_Pin1_4 75 80 PF00397 0.394
LIG_14-3-3_CanoR_1 92 100 PF00244 0.416
LIG_Actin_WH2_2 93 110 PF00022 0.466
LIG_BRCT_BRCA1_1 139 143 PF00533 0.444
LIG_FHA_1 213 219 PF00498 0.517
LIG_FHA_2 100 106 PF00498 0.494
LIG_FHA_2 111 117 PF00498 0.366
LIG_FHA_2 191 197 PF00498 0.563
LIG_Integrin_RGD_1 194 196 PF01839 0.417
LIG_LIR_Apic_2 2 8 PF02991 0.396
LIG_LIR_Apic_2 228 234 PF02991 0.776
LIG_LIR_Gen_1 196 205 PF02991 0.496
LIG_LIR_Nem_3 196 202 PF02991 0.430
LIG_NRBOX 154 160 PF00104 0.469
LIG_SH2_CRK 253 257 PF00017 0.617
LIG_SH2_GRB2like 88 91 PF00017 0.433
LIG_SH2_PTP2 231 234 PF00017 0.566
LIG_SH2_STAT5 18 21 PF00017 0.401
LIG_SH2_STAT5 199 202 PF00017 0.499
LIG_SH2_STAT5 231 234 PF00017 0.627
LIG_SH2_STAT5 41 44 PF00017 0.410
LIG_SH2_STAT5 5 8 PF00017 0.612
LIG_SH3_3 135 141 PF00018 0.493
LIG_SH3_3 229 235 PF00018 0.650
LIG_SH3_3 73 79 PF00018 0.542
LIG_TRFH_1 231 235 PF08558 0.601
LIG_UBA3_1 168 177 PF00899 0.450
MOD_CK1_1 148 154 PF00069 0.521
MOD_CK1_1 182 188 PF00069 0.481
MOD_CK1_1 237 243 PF00069 0.676
MOD_CK1_1 4 10 PF00069 0.441
MOD_CK2_1 110 116 PF00069 0.458
MOD_CK2_1 237 243 PF00069 0.544
MOD_CK2_1 271 277 PF00069 0.620
MOD_CK2_1 99 105 PF00069 0.454
MOD_GlcNHglycan 150 153 PF01048 0.454
MOD_GlcNHglycan 187 190 PF01048 0.532
MOD_GlcNHglycan 237 240 PF01048 0.794
MOD_GlcNHglycan 245 248 PF01048 0.581
MOD_GlcNHglycan 256 259 PF01048 0.432
MOD_GlcNHglycan 273 276 PF01048 0.570
MOD_GlcNHglycan 93 96 PF01048 0.428
MOD_GSK3_1 164 171 PF00069 0.619
MOD_GSK3_1 179 186 PF00069 0.413
MOD_GSK3_1 197 204 PF00069 0.391
MOD_GSK3_1 212 219 PF00069 0.469
MOD_GSK3_1 234 241 PF00069 0.618
MOD_N-GLC_1 148 153 PF02516 0.429
MOD_N-GLC_1 53 58 PF02516 0.479
MOD_NEK2_1 1 6 PF00069 0.650
MOD_NEK2_1 183 188 PF00069 0.514
MOD_PKA_2 162 168 PF00069 0.525
MOD_PKA_2 91 97 PF00069 0.531
MOD_Plk_2-3 281 287 PF00069 0.524
MOD_Plk_4 1 7 PF00069 0.535
MOD_Plk_4 164 170 PF00069 0.479
MOD_ProDKin_1 137 143 PF00069 0.472
MOD_ProDKin_1 252 258 PF00069 0.707
MOD_ProDKin_1 4 10 PF00069 0.368
MOD_ProDKin_1 75 81 PF00069 0.384
MOD_SUMO_rev_2 140 148 PF00179 0.496
MOD_SUMO_rev_2 286 295 PF00179 0.595
TRG_ENDOCYTIC_2 199 202 PF00928 0.487
TRG_Pf-PMV_PEXEL_1 157 161 PF00026 0.571
TRG_Pf-PMV_PEXEL_1 22 26 PF00026 0.469

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PAJ7 Leptomonas seymouri 41% 100%
A0A0N1PCN3 Leptomonas seymouri 35% 82%
A0A3Q8IJW3 Leishmania donovani 98% 100%
A4HJ55 Leishmania braziliensis 65% 100%
E9B1M6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%
Q9BHD3 Leishmania major 89% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS