LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I6G7_LEIIN
TriTrypDb:
LINF_310013000
Length:
110

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I6G7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6G7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 78 82 PF00656 0.480
CLV_NRD_NRD_1 89 91 PF00675 0.451
CLV_PCSK_KEX2_1 89 91 PF00082 0.463
CLV_PCSK_SKI1_1 39 43 PF00082 0.619
DEG_APCC_DBOX_1 89 97 PF00400 0.520
DEG_COP1_1 21 29 PF00400 0.565
DEG_SPOP_SBC_1 29 33 PF00917 0.525
DOC_CYCLIN_yCln2_LP_2 53 59 PF00134 0.488
DOC_MAPK_gen_1 46 53 PF00069 0.579
DOC_MAPK_MEF2A_6 46 53 PF00069 0.506
DOC_PP2B_LxvP_1 14 17 PF13499 0.572
DOC_PP4_FxxP_1 6 9 PF00568 0.555
DOC_USP7_MATH_1 106 110 PF00917 0.552
DOC_USP7_MATH_1 29 33 PF00917 0.621
DOC_USP7_MATH_1 99 103 PF00917 0.569
LIG_14-3-3_CanoR_1 39 49 PF00244 0.604
LIG_14-3-3_CterR_2 105 110 PF00244 0.542
LIG_BIR_II_1 1 5 PF00653 0.641
LIG_BRCT_BRCA1_1 2 6 PF00533 0.487
LIG_FHA_1 75 81 PF00498 0.522
LIG_LIR_Apic_2 3 9 PF02991 0.518
LIG_LIR_Nem_3 18 22 PF02991 0.485
LIG_SH2_STAT5 86 89 PF00017 0.560
MOD_CK1_1 25 31 PF00069 0.524
MOD_CK2_1 15 21 PF00069 0.574
MOD_CK2_1 98 104 PF00069 0.509
MOD_GlcNHglycan 101 104 PF01048 0.673
MOD_GlcNHglycan 27 30 PF01048 0.639
MOD_GSK3_1 25 32 PF00069 0.524
MOD_PIKK_1 20 26 PF00454 0.580
MOD_SUMO_rev_2 38 48 PF00179 0.581
TRG_ENDOCYTIC_2 19 22 PF00928 0.596

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S5H7P5 Leishmania donovani 97% 100%
A4HJ53 Leishmania braziliensis 55% 100%
E9B1M4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 100%
Q4Q6J0 Leishmania major 75% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS