LeishMANIAdb
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BRCT domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
BRCT domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I6G1_LEIIN
TriTrypDb:
LINF_310012400
Length:
1197

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I6G1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6G1

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 313 317 PF00656 0.596
CLV_C14_Caspase3-7 93 97 PF00656 0.598
CLV_NRD_NRD_1 1020 1022 PF00675 0.577
CLV_NRD_NRD_1 158 160 PF00675 0.768
CLV_NRD_NRD_1 298 300 PF00675 0.754
CLV_NRD_NRD_1 484 486 PF00675 0.724
CLV_NRD_NRD_1 548 550 PF00675 0.753
CLV_NRD_NRD_1 572 574 PF00675 0.564
CLV_NRD_NRD_1 715 717 PF00675 0.626
CLV_NRD_NRD_1 723 725 PF00675 0.506
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I1U6 Leptomonas seymouri 38% 100%
A0A3Q8IID3 Leishmania donovani 100% 100%
A4HJ45 Leishmania braziliensis 57% 96%
E9B1L8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 100%
Q4Q6J6 Leishmania major 88% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS