LeishMANIAdb
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DNA-directed RNA polymerase subunit beta

Quick info Annotations Function or PPIs Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
DNA-directed RNA polymerase subunit beta
Gene product:
DNA-directed RNA polymerase II subunit 2 - putative
Species:
Leishmania infantum
UniProt:
A4I6A8_LEIIN
TriTrypDb:
LINF_310006600
Length:
1181

Annotations

Annotations by Jardim et al.

Polymerase, DNA-directed RNA polymerase

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0000428 DNA-directed RNA polymerase complex 4 12
GO:0030880 RNA polymerase complex 3 12
GO:0032991 protein-containing complex 1 12
GO:0061695 transferase complex, transferring phosphorus-containing groups 4 12
GO:0140535 intracellular protein-containing complex 2 12
GO:1902494 catalytic complex 2 12
GO:1990234 transferase complex 3 12
GO:0005665 RNA polymerase II, core complex 4 1
GO:0055029 nuclear DNA-directed RNA polymerase complex 3 1
GO:0140513 nuclear protein-containing complex 2 1

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

A4I6A8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I6A8

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 12
GO:0006351 DNA-templated transcription 7 12
GO:0006725 cellular aromatic compound metabolic process 3 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009058 biosynthetic process 2 12
GO:0009059 macromolecule biosynthetic process 4 12
GO:0009987 cellular process 1 12
GO:0016070 RNA metabolic process 5 12
GO:0018130 heterocycle biosynthetic process 4 12
GO:0019438 aromatic compound biosynthetic process 4 12
GO:0032774 RNA biosynthetic process 5 12
GO:0034641 cellular nitrogen compound metabolic process 3 12
GO:0034654 nucleobase-containing compound biosynthetic process 4 12
GO:0043170 macromolecule metabolic process 3 12
GO:0044237 cellular metabolic process 2 12
GO:0044238 primary metabolic process 2 12
GO:0044249 cellular biosynthetic process 3 12
GO:0044271 cellular nitrogen compound biosynthetic process 4 12
GO:0046483 heterocycle metabolic process 3 12
GO:0071704 organic substance metabolic process 2 12
GO:0090304 nucleic acid metabolic process 4 12
GO:0097659 nucleic acid-templated transcription 6 12
GO:1901360 organic cyclic compound metabolic process 3 12
GO:1901362 organic cyclic compound biosynthetic process 4 12
GO:1901576 organic substance biosynthetic process 3 12
Molecular functions
Term Name Level Count
GO:0001882 nucleoside binding 3 12
GO:0003676 nucleic acid binding 3 12
GO:0003677 DNA binding 4 12
GO:0003824 catalytic activity 1 12
GO:0003899 DNA-directed 5'-3' RNA polymerase activity 6 12
GO:0005488 binding 1 12
GO:0016740 transferase activity 2 12
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 12
GO:0016779 nucleotidyltransferase activity 4 12
GO:0032549 ribonucleoside binding 4 12
GO:0034062 5'-3' RNA polymerase activity 5 12
GO:0036094 small molecule binding 2 12
GO:0043167 ion binding 2 12
GO:0043169 cation binding 3 12
GO:0046872 metal ion binding 4 12
GO:0097159 organic cyclic compound binding 2 12
GO:0097367 carbohydrate derivative binding 2 12
GO:0097747 RNA polymerase activity 4 12
GO:0140098 catalytic activity, acting on RNA 3 12
GO:0140640 catalytic activity, acting on a nucleic acid 2 12
GO:1901363 heterocyclic compound binding 2 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 27 31 PF00656 0.434
CLV_C14_Caspase3-7 311 315 PF00656 0.464
CLV_C14_Caspase3-7 895 899 PF00656 0.472
CLV_NRD_NRD_1 332 334 PF00675 0.297
CLV_NRD_NRD_1 419 421 PF00675 0.212
CLV_NRD_NRD_1 454 456 PF00675 0.326
CLV_NRD_NRD_1 491 493 PF00675 0.211
CLV_NRD_NRD_1 600 602 PF00675 0.213
CLV_NRD_NRD_1 643 645 PF00675 0.412
CLV_PCSK_FUR_1 597 601 PF00082 0.212
CLV_PCSK_FUR_1 827 831 PF00082 0.297
CLV_PCSK_FUR_1 845 849 PF00082 0.236
CLV_PCSK_KEX2_1 332 334 PF00082 0.211
CLV_PCSK_KEX2_1 399 401 PF00082 0.252
CLV_PCSK_KEX2_1 454 456 PF00082 0.326
CLV_PCSK_KEX2_1 491 493 PF00082 0.211
CLV_PCSK_KEX2_1 599 601 PF00082 0.212
CLV_PCSK_KEX2_1 829 831 PF00082 0.252
CLV_PCSK_KEX2_1 847 849 PF00082 0.211
CLV_PCSK_KEX2_1 896 898 PF00082 0.211
CLV_PCSK_PC1ET2_1 399 401 PF00082 0.211
CLV_PCSK_PC1ET2_1 829 831 PF00082 0.252
CLV_PCSK_PC1ET2_1 847 849 PF00082 0.211
CLV_PCSK_PC1ET2_1 896 898 PF00082 0.211
CLV_PCSK_SKI1_1 1161 1165 PF00082 0.211
CLV_PCSK_SKI1_1 128 132 PF00082 0.211
CLV_PCSK_SKI1_1 225 229 PF00082 0.223
CLV_PCSK_SKI1_1 289 293 PF00082 0.211
CLV_PCSK_SKI1_1 353 357 PF00082 0.223
CLV_PCSK_SKI1_1 379 383 PF00082 0.236
CLV_PCSK_SKI1_1 393 397 PF00082 0.211
CLV_PCSK_SKI1_1 435 439 PF00082 0.254
CLV_PCSK_SKI1_1 447 451 PF00082 0.162
CLV_PCSK_SKI1_1 631 635 PF00082 0.211
CLV_PCSK_SKI1_1 649 653 PF00082 0.398
CLV_PCSK_SKI1_1 769 773 PF00082 0.297
CLV_PCSK_SKI1_1 810 814 PF00082 0.206
CLV_PCSK_SKI1_1 819 823 PF00082 0.210
CLV_PCSK_SKI1_1 830 834 PF00082 0.198
CLV_PCSK_SKI1_1 913 917 PF00082 0.211
CLV_PCSK_SKI1_1 93 97 PF00082 0.297
CLV_PCSK_SKI1_1 930 934 PF00082 0.211
CLV_Separin_Metazoa 183 187 PF03568 0.411
CLV_Separin_Metazoa 306 310 PF03568 0.411
DEG_APCC_DBOX_1 1068 1076 PF00400 0.411
DEG_APCC_DBOX_1 1108 1116 PF00400 0.411
DEG_APCC_DBOX_1 352 360 PF00400 0.418
DEG_APCC_DBOX_1 92 100 PF00400 0.423
DEG_SCF_FBW7_1 1003 1010 PF00400 0.411
DOC_CDC14_PxL_1 1170 1178 PF14671 0.411
DOC_CKS1_1 1004 1009 PF01111 0.423
DOC_CKS1_1 520 525 PF01111 0.411
DOC_CYCLIN_RxL_1 1158 1166 PF00134 0.411
DOC_CYCLIN_RxL_1 222 230 PF00134 0.423
DOC_CYCLIN_RxL_1 628 637 PF00134 0.411
DOC_MAPK_DCC_7 964 973 PF00069 0.423
DOC_MAPK_gen_1 61 71 PF00069 0.430
DOC_MAPK_gen_1 613 622 PF00069 0.418
DOC_MAPK_gen_1 670 676 PF00069 0.424
DOC_MAPK_gen_1 926 934 PF00069 0.415
DOC_MAPK_JIP1_4 241 247 PF00069 0.411
DOC_MAPK_MEF2A_6 241 249 PF00069 0.411
DOC_MAPK_MEF2A_6 89 96 PF00069 0.497
DOC_MAPK_MEF2A_6 964 973 PF00069 0.423
DOC_PP1_RVXF_1 1159 1165 PF00149 0.411
DOC_PP1_RVXF_1 659 666 PF00149 0.393
DOC_PP4_FxxP_1 1047 1050 PF00568 0.411
DOC_PP4_FxxP_1 836 839 PF00568 0.411
DOC_USP7_MATH_1 1007 1011 PF00917 0.411
DOC_USP7_MATH_1 1022 1026 PF00917 0.411
DOC_USP7_MATH_1 498 502 PF00917 0.474
DOC_USP7_MATH_1 977 981 PF00917 0.411
DOC_USP7_UBL2_3 421 425 PF12436 0.436
DOC_USP7_UBL2_3 656 660 PF12436 0.568
DOC_WW_Pin1_4 1003 1008 PF00397 0.411
DOC_WW_Pin1_4 148 153 PF00397 0.472
DOC_WW_Pin1_4 519 524 PF00397 0.411
DOC_WW_Pin1_4 687 692 PF00397 0.497
DOC_WW_Pin1_4 723 728 PF00397 0.404
LIG_14-3-3_CanoR_1 1114 1121 PF00244 0.411
LIG_14-3-3_CanoR_1 1150 1158 PF00244 0.423
LIG_14-3-3_CanoR_1 309 318 PF00244 0.497
LIG_14-3-3_CanoR_1 435 441 PF00244 0.496
LIG_14-3-3_CanoR_1 480 490 PF00244 0.411
LIG_14-3-3_CanoR_1 621 630 PF00244 0.411
LIG_14-3-3_CanoR_1 728 732 PF00244 0.402
LIG_14-3-3_CanoR_1 904 911 PF00244 0.423
LIG_14-3-3_CanoR_1 981 985 PF00244 0.411
LIG_Actin_WH2_2 450 468 PF00022 0.410
LIG_APCC_ABBA_1 620 625 PF00400 0.411
LIG_BIR_II_1 1 5 PF00653 0.688
LIG_BRCT_BRCA1_1 38 42 PF00533 0.322
LIG_Clathr_ClatBox_1 6 10 PF01394 0.675
LIG_deltaCOP1_diTrp_1 32 42 PF00928 0.333
LIG_EH1_1 374 382 PF00400 0.423
LIG_eIF4E_1 1158 1164 PF01652 0.411
LIG_eIF4E_1 375 381 PF01652 0.411
LIG_eIF4E_1 760 766 PF01652 0.411
LIG_FHA_1 1118 1124 PF00498 0.492
LIG_FHA_1 1127 1133 PF00498 0.468
LIG_FHA_1 137 143 PF00498 0.423
LIG_FHA_1 201 207 PF00498 0.411
LIG_FHA_1 242 248 PF00498 0.411
LIG_FHA_1 271 277 PF00498 0.472
LIG_FHA_1 300 306 PF00498 0.472
LIG_FHA_1 315 321 PF00498 0.350
LIG_FHA_1 366 372 PF00498 0.490
LIG_FHA_1 407 413 PF00498 0.423
LIG_FHA_1 448 454 PF00498 0.461
LIG_FHA_1 465 471 PF00498 0.439
LIG_FHA_1 560 566 PF00498 0.502
LIG_FHA_1 752 758 PF00498 0.411
LIG_FHA_1 854 860 PF00498 0.452
LIG_FHA_1 874 880 PF00498 0.280
LIG_FHA_1 929 935 PF00498 0.422
LIG_FHA_1 948 954 PF00498 0.333
LIG_FHA_2 149 155 PF00498 0.516
LIG_FHA_2 320 326 PF00498 0.423
LIG_FHA_2 389 395 PF00498 0.411
LIG_FHA_2 424 430 PF00498 0.415
LIG_FHA_2 688 694 PF00498 0.423
LIG_FHA_2 82 88 PF00498 0.447
LIG_FHA_2 893 899 PF00498 0.465
LIG_LIR_Apic_2 1002 1007 PF02991 0.424
LIG_LIR_Apic_2 834 839 PF02991 0.411
LIG_LIR_Gen_1 1006 1016 PF02991 0.411
LIG_LIR_Gen_1 1051 1059 PF02991 0.411
LIG_LIR_Gen_1 258 268 PF02991 0.473
LIG_LIR_Gen_1 32 42 PF02991 0.333
LIG_LIR_Gen_1 53 63 PF02991 0.411
LIG_LIR_Gen_1 850 859 PF02991 0.411
LIG_LIR_Gen_1 922 932 PF02991 0.473
LIG_LIR_Nem_3 1006 1011 PF02991 0.411
LIG_LIR_Nem_3 1051 1056 PF02991 0.411
LIG_LIR_Nem_3 1116 1121 PF02991 0.411
LIG_LIR_Nem_3 258 263 PF02991 0.473
LIG_LIR_Nem_3 32 38 PF02991 0.348
LIG_LIR_Nem_3 439 443 PF02991 0.423
LIG_LIR_Nem_3 459 465 PF02991 0.176
LIG_LIR_Nem_3 512 517 PF02991 0.411
LIG_LIR_Nem_3 53 58 PF02991 0.418
LIG_LIR_Nem_3 558 563 PF02991 0.465
LIG_LIR_Nem_3 790 795 PF02991 0.511
LIG_LIR_Nem_3 815 821 PF02991 0.409
LIG_LIR_Nem_3 850 854 PF02991 0.411
LIG_LIR_Nem_3 922 927 PF02991 0.473
LIG_MLH1_MIPbox_1 38 42 PF16413 0.322
LIG_MYND_1 118 122 PF01753 0.472
LIG_PCNA_yPIPBox_3 532 540 PF02747 0.411
LIG_Pex14_2 1048 1052 PF04695 0.497
LIG_Pex14_2 813 817 PF04695 0.411
LIG_Rb_LxCxE_1 675 695 PF01857 0.423
LIG_REV1ctd_RIR_1 39 49 PF16727 0.321
LIG_REV1ctd_RIR_1 810 818 PF16727 0.411
LIG_SH2_CRK 1004 1008 PF00017 0.423
LIG_SH2_CRK 1053 1057 PF00017 0.411
LIG_SH2_NCK_1 1004 1008 PF00017 0.423
LIG_SH2_PTP2 516 519 PF00017 0.411
LIG_SH2_PTP2 673 676 PF00017 0.411
LIG_SH2_SRC 79 82 PF00017 0.497
LIG_SH2_STAP1 1119 1123 PF00017 0.411
LIG_SH2_STAP1 1158 1162 PF00017 0.411
LIG_SH2_STAP1 132 136 PF00017 0.411
LIG_SH2_STAP1 483 487 PF00017 0.411
LIG_SH2_STAP1 743 747 PF00017 0.411
LIG_SH2_STAT3 132 135 PF00017 0.497
LIG_SH2_STAT5 111 114 PF00017 0.497
LIG_SH2_STAT5 1119 1122 PF00017 0.497
LIG_SH2_STAT5 197 200 PF00017 0.411
LIG_SH2_STAT5 219 222 PF00017 0.497
LIG_SH2_STAT5 329 332 PF00017 0.497
LIG_SH2_STAT5 516 519 PF00017 0.411
LIG_SH2_STAT5 673 676 PF00017 0.411
LIG_SH3_3 1065 1071 PF00018 0.411
LIG_SH3_3 1073 1079 PF00018 0.411
LIG_SH3_3 113 119 PF00018 0.436
LIG_SH3_3 1151 1157 PF00018 0.423
LIG_SH3_3 517 523 PF00018 0.411
LIG_SH3_3 758 764 PF00018 0.411
LIG_SUMO_SIM_anti_2 608 614 PF11976 0.411
LIG_SUMO_SIM_par_1 165 171 PF11976 0.411
LIG_SUMO_SIM_par_1 4 11 PF11976 0.676
LIG_SUMO_SIM_par_1 785 790 PF11976 0.516
LIG_TRAF2_1 322 325 PF00917 0.516
LIG_TRAF2_1 823 826 PF00917 0.411
LIG_TRAF2_1 84 87 PF00917 0.476
LIG_UBA3_1 59 64 PF00899 0.497
LIG_UBA3_1 987 994 PF00899 0.411
LIG_WRC_WIRS_1 218 223 PF05994 0.497
LIG_WRC_WIRS_1 38 43 PF05994 0.316
LIG_WRC_WIRS_1 412 417 PF05994 0.436
LIG_WRC_WIRS_1 437 442 PF05994 0.423
LIG_WRC_WIRS_1 833 838 PF05994 0.497
MOD_CDK_SPK_2 723 728 PF00069 0.404
MOD_CK1_1 105 111 PF00069 0.435
MOD_CK1_1 313 319 PF00069 0.497
MOD_CK1_1 485 491 PF00069 0.411
MOD_CK1_1 501 507 PF00069 0.411
MOD_CK1_1 541 547 PF00069 0.368
MOD_CK1_1 664 670 PF00069 0.371
MOD_CK1_1 790 796 PF00069 0.528
MOD_CK1_1 900 906 PF00069 0.420
MOD_CK1_1 980 986 PF00069 0.411
MOD_CK2_1 230 236 PF00069 0.411
MOD_CK2_1 255 261 PF00069 0.476
MOD_CK2_1 319 325 PF00069 0.441
MOD_CK2_1 687 693 PF00069 0.408
MOD_CK2_1 698 704 PF00069 0.390
MOD_CK2_1 803 809 PF00069 0.411
MOD_CK2_1 81 87 PF00069 0.509
MOD_Cter_Amidation 330 333 PF01082 0.211
MOD_Cter_Amidation 658 661 PF01082 0.463
MOD_GlcNHglycan 1059 1062 PF01048 0.223
MOD_GlcNHglycan 176 179 PF01048 0.297
MOD_GlcNHglycan 257 260 PF01048 0.256
MOD_GlcNHglycan 362 366 PF01048 0.272
MOD_GlcNHglycan 645 648 PF01048 0.436
MOD_GlcNHglycan 732 735 PF01048 0.211
MOD_GlcNHglycan 792 795 PF01048 0.213
MOD_GlcNHglycan 805 808 PF01048 0.194
MOD_GlcNHglycan 814 817 PF01048 0.211
MOD_GSK3_1 1003 1010 PF00069 0.411
MOD_GSK3_1 1098 1105 PF00069 0.411
MOD_GSK3_1 1113 1120 PF00069 0.411
MOD_GSK3_1 148 155 PF00069 0.497
MOD_GSK3_1 310 317 PF00069 0.497
MOD_GSK3_1 361 368 PF00069 0.477
MOD_GSK3_1 443 450 PF00069 0.435
MOD_GSK3_1 479 486 PF00069 0.411
MOD_GSK3_1 497 504 PF00069 0.411
MOD_GSK3_1 603 610 PF00069 0.411
MOD_GSK3_1 723 730 PF00069 0.405
MOD_GSK3_1 765 772 PF00069 0.402
MOD_GSK3_1 797 804 PF00069 0.405
MOD_GSK3_1 849 856 PF00069 0.452
MOD_GSK3_1 885 892 PF00069 0.454
MOD_GSK3_1 899 906 PF00069 0.429
MOD_LATS_1 445 451 PF00433 0.423
MOD_N-GLC_1 1146 1151 PF02516 0.223
MOD_N-GLC_1 174 179 PF02516 0.297
MOD_N-GLC_1 200 205 PF02516 0.223
MOD_N-GLC_1 365 370 PF02516 0.297
MOD_N-GLC_1 578 583 PF02516 0.223
MOD_N-GLC_1 723 728 PF02516 0.211
MOD_N-GLC_2 1030 1032 PF02516 0.223
MOD_N-GLC_2 1125 1127 PF02516 0.223
MOD_N-GLC_2 123 125 PF02516 0.211
MOD_N-GLC_2 188 190 PF02516 0.211
MOD_NEK2_1 1126 1131 PF00069 0.459
MOD_NEK2_1 1168 1173 PF00069 0.472
MOD_NEK2_1 168 173 PF00069 0.411
MOD_NEK2_1 270 275 PF00069 0.472
MOD_NEK2_1 299 304 PF00069 0.497
MOD_NEK2_1 308 313 PF00069 0.497
MOD_NEK2_1 423 428 PF00069 0.411
MOD_NEK2_1 481 486 PF00069 0.411
MOD_NEK2_1 509 514 PF00069 0.411
MOD_NEK2_1 643 648 PF00069 0.374
MOD_NEK2_1 65 70 PF00069 0.436
MOD_NEK2_1 751 756 PF00069 0.402
MOD_NEK2_1 765 770 PF00069 0.402
MOD_NEK2_1 803 808 PF00069 0.410
MOD_NEK2_1 812 817 PF00069 0.401
MOD_NEK2_1 987 992 PF00069 0.411
MOD_PIKK_1 1022 1028 PF00454 0.477
MOD_PIKK_1 1102 1108 PF00454 0.411
MOD_PIKK_1 1149 1155 PF00454 0.423
MOD_PIKK_1 509 515 PF00454 0.411
MOD_PK_1 897 903 PF00069 0.411
MOD_PKA_2 1113 1119 PF00069 0.411
MOD_PKA_2 1149 1155 PF00069 0.423
MOD_PKA_2 308 314 PF00069 0.423
MOD_PKA_2 479 485 PF00069 0.411
MOD_PKA_2 541 547 PF00069 0.368
MOD_PKA_2 643 649 PF00069 0.472
MOD_PKA_2 727 733 PF00069 0.411
MOD_PKA_2 903 909 PF00069 0.423
MOD_PKA_2 922 928 PF00069 0.395
MOD_PKA_2 980 986 PF00069 0.411
MOD_PKB_1 126 134 PF00069 0.411
MOD_Plk_1 1146 1152 PF00069 0.418
MOD_Plk_1 128 134 PF00069 0.411
MOD_Plk_1 270 276 PF00069 0.472
MOD_Plk_1 313 319 PF00069 0.411
MOD_Plk_1 607 613 PF00069 0.411
MOD_Plk_1 681 687 PF00069 0.497
MOD_Plk_1 797 803 PF00069 0.411
MOD_Plk_1 897 903 PF00069 0.414
MOD_Plk_2-3 230 236 PF00069 0.411
MOD_Plk_2-3 28 34 PF00069 0.424
MOD_Plk_4 1007 1013 PF00069 0.423
MOD_Plk_4 1048 1054 PF00069 0.411
MOD_Plk_4 107 113 PF00069 0.497
MOD_Plk_4 1168 1174 PF00069 0.469
MOD_Plk_4 152 158 PF00069 0.472
MOD_Plk_4 230 236 PF00069 0.411
MOD_Plk_4 291 297 PF00069 0.411
MOD_Plk_4 346 352 PF00069 0.497
MOD_Plk_4 37 43 PF00069 0.315
MOD_Plk_4 403 409 PF00069 0.472
MOD_Plk_4 411 417 PF00069 0.472
MOD_Plk_4 578 584 PF00069 0.411
MOD_Plk_4 607 613 PF00069 0.411
MOD_Plk_4 681 687 PF00069 0.407
MOD_Plk_4 705 711 PF00069 0.430
MOD_Plk_4 713 719 PF00069 0.264
MOD_Plk_4 769 775 PF00069 0.411
MOD_Plk_4 797 803 PF00069 0.407
MOD_ProDKin_1 1003 1009 PF00069 0.411
MOD_ProDKin_1 148 154 PF00069 0.472
MOD_ProDKin_1 519 525 PF00069 0.411
MOD_ProDKin_1 687 693 PF00069 0.497
MOD_ProDKin_1 723 729 PF00069 0.404
MOD_SUMO_for_1 823 826 PF00179 0.497
TRG_DiLeu_BaEn_1 346 351 PF01217 0.436
TRG_DiLeu_BaEn_1 681 686 PF01217 0.411
TRG_DiLeu_BaLyEn_6 588 593 PF01217 0.423
TRG_ENDOCYTIC_2 1053 1056 PF00928 0.411
TRG_ENDOCYTIC_2 1118 1121 PF00928 0.411
TRG_ENDOCYTIC_2 197 200 PF00928 0.411
TRG_ENDOCYTIC_2 55 58 PF00928 0.411
TRG_ENDOCYTIC_2 673 676 PF00928 0.411
TRG_ENDOCYTIC_2 851 854 PF00928 0.411
TRG_ER_diArg_1 332 334 PF00400 0.497
TRG_ER_diArg_1 453 455 PF00400 0.325
TRG_ER_diArg_1 490 492 PF00400 0.411
TRG_ER_diArg_1 596 599 PF00400 0.411
TRG_Pf-PMV_PEXEL_1 332 337 PF00026 0.297
TRG_Pf-PMV_PEXEL_1 591 595 PF00026 0.223
TRG_Pf-PMV_PEXEL_1 613 617 PF00026 0.211
TRG_Pf-PMV_PEXEL_1 865 870 PF00026 0.274

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P4S3 Leptomonas seymouri 34% 100%
A0A0N0P6L8 Leptomonas seymouri 27% 73%
A0A0N1PFE3 Leptomonas seymouri 95% 99%
A0A0S4IQ42 Bodo saltans 35% 100%
A0A0S4J556 Bodo saltans 75% 100%
A0A0S4JAX3 Bodo saltans 27% 70%
A0A1X0NKP7 Trypanosomatidae 81% 98%
A0A1X0NXA3 Trypanosomatidae 35% 100%
A0A1X0P5I4 Trypanosomatidae 29% 74%
A0A3Q8ICE2 Leishmania donovani 27% 73%
A0A3R7N5U9 Trypanosoma rangeli 82% 100%
A0A3S7WVP1 Leishmania donovani 35% 100%
A0A3S7X436 Leishmania donovani 100% 100%
A0A422N812 Trypanosoma rangeli 35% 100%
A0A422NX41 Trypanosoma rangeli 25% 74%
A0LRL3 Acidothermus cellulolyticus (strain ATCC 43068 / DSM 8971 / 11B) 25% 100%
A0PM24 Mycobacterium ulcerans (strain Agy99) 24% 100%
A1A317 Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) 24% 100%
A1KGE7 Mycobacterium bovis (strain BCG / Pasteur 1173P2) 25% 100%
A4FPP3 Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) 23% 100%
A4HBG9 Leishmania braziliensis 35% 100%
A4HEF6 Leishmania braziliensis 26% 75%
A4HIZ1 Leishmania braziliensis 98% 100%
A4I1A3 Leishmania infantum 27% 73%
A4QLI6 Lobularia maritima 22% 100%
A4T1P4 Mycolicibacterium gilvum (strain PYR-GCK) 25% 100%
A5DHT2 Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) 44% 96%
A5IJW3 Thermotoga petrophila (strain ATCC BAA-488 / DSM 13995 / JCM 10881 / RKU-1) 26% 94%
A5U052 Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) 25% 100%
B1VES1 Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) 25% 100%
B2HSJ3 Mycobacterium marinum (strain ATCC BAA-535 / M) 25% 100%
B3DTE2 Bifidobacterium longum (strain DJO10A) 24% 99%
B5RLU9 Borrelia duttonii (strain Ly) 25% 100%
B5RRJ7 Borrelia recurrentis (strain A1) 24% 100%
B7GUG7 Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12) 24% 99%
B8JKD7 Danio rerio 29% 100%
B8YB55 Saccharolobus shibatae 36% 100%
B8ZSC7 Mycobacterium leprae (strain Br4923) 24% 100%
C0ZVQ6 Rhodococcus erythropolis (strain PR4 / NBRC 100887) 25% 100%
C9ZHX4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 100%
C9ZN35 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 79% 99%
D0A5J5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 76%
E9AGT7 Leishmania infantum 35% 100%
E9AUE0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 35% 100%
E9AXD9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 73%
E9B1G4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 99% 100%
F4I366 Arabidopsis thaliana 28% 100%
F4KD38 Arabidopsis thaliana 35% 100%
O54888 Rattus norvegicus 29% 100%
O57230 Vaccinia virus (strain Ankara) 27% 100%
O74633 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 29% 96%
P08266 Drosophila melanogaster 47% 100%
P08518 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 45% 96%
P0A681 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 25% 100%
P0C8K2 African swine fever virus (isolate Pig/Kenya/KEN-50/1950) 27% 95%
P0C8K3 African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) 27% 95%
P0C8K4 African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) 27% 95%
P0C8K5 African swine fever virus (isolate Warthog/Namibia/Wart80/1980) 27% 95%
P0DST3 Variola virus (isolate Human/India/Ind3/1967) 26% 100%
P0DST4 Variola virus 26% 100%
P11513 Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) 38% 100%
P11703 Spinacia oleracea 23% 100%
P16716 Sheeppox virus (strain KS-1) 27% 100%
P17474 Cowpox virus (strain Brighton Red) 27% 100%
P20028 Drosophila melanogaster 27% 100%
P22138 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 29% 98%
P22276 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 35% 100%
P23579 Euglena gracilis 25% 100%
P25167 Drosophila melanogaster 35% 100%
P28365 Euplotoides octocarinatus 29% 100%
P30760 Mycobacterium leprae (strain TN) 24% 100%
P30876 Homo sapiens 46% 100%
P31814 Thermococcus celer 37% 100%
P38420 Arabidopsis thaliana 45% 99%
P42487 African swine fever virus (strain Badajoz 1971 Vero-adapted) 28% 95%
P48119 Cyanophora paradoxa 23% 100%
P59470 Mus musculus 36% 100%
P59642 Tropheryma whipplei (strain TW08/27) 24% 100%
P59643 Tropheryma whipplei 24% 100%
P68694 Vaccinia virus (strain Copenhagen) 27% 100%
P70700 Mus musculus 29% 100%
P9WGY8 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 25% 100%
P9WGY9 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 25% 100%
Q02061 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 43% 98%
Q03587 Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) 33% 99%
Q09MI6 Citrus sinensis 22% 100%
Q10233 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 36% 100%
Q10578 Caenorhabditis elegans 46% 99%
Q197F1 Invertebrate iridescent virus 3 30% 100%
Q1KXX2 Helianthus annuus 23% 100%
Q42877 Solanum lycopersicum 45% 99%
Q4Q6P8 Leishmania major 99% 100%
Q4QA33 Leishmania major 27% 73%
Q4QD43 Leishmania major 35% 100%
Q54BM1 Dictyostelium discoideum 29% 100%
Q54J75 Dictyostelium discoideum 45% 100%
Q56P13 Lactuca sativa 23% 100%
Q5REE8 Pongo abelii 29% 100%
Q6FLD5 Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) 44% 97%
Q6GZR3 Frog virus 3 (isolate Goorha) 30% 97%
Q6RZF8 Rabbitpox virus (strain Utrecht) 27% 100%
Q753Q4 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 44% 97%
Q75DS1 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 29% 99%
Q76ZP7 Vaccinia virus (strain Western Reserve) 27% 100%
Q775Q3 Camelpox virus (strain CMS) 27% 100%
Q7T6X7 Acanthamoeba polyphaga mimivirus 32% 99%
Q80DV1 Cowpox virus (strain GRI-90 / Grishak) 26% 100%
Q8CFI7 Mus musculus 46% 100%
Q8FS97 Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395) 24% 100%
Q8G514 Bifidobacterium longum (strain NCC 2705) 24% 99%
Q8JL90 Ectromelia virus (strain Moscow) 26% 100%
Q8SR75 Encephalitozoon cuniculi (strain GB-M1) 45% 100%
Q8V2N1 Camelpox virus (strain M-96) 27% 100%
Q8V4V3 Monkeypox virus (strain Zaire-96-I-16) 26% 100%
Q8WI24 Psilotum nudum 23% 100%
Q91F97 Invertebrate iridescent virus 6 31% 99%
Q93GF2 Tropheryma whipplei (strain Twist) 24% 100%
Q980R1 Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) 36% 100%
Q9H9Y6 Homo sapiens 29% 100%
Q9J544 Fowlpox virus (strain NVSL) 27% 100%
Q9JF79 Vaccinia virus (strain Tian Tan) 26% 100%
Q9KWU7 Thermus aquaticus 24% 100%
Q9LK40 Arabidopsis thaliana 32% 100%
Q9LV32 Arabidopsis thaliana 32% 100%
Q9NW08 Homo sapiens 36% 100%
Q9P7X8 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 29% 100%
V5AYL6 Trypanosoma cruzi 81% 100%
V5B7L4 Trypanosoma cruzi 25% 74%
V5BAG3 Trypanosoma cruzi 35% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS