ATP metabolism, ATP synthase, epsilon chain
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | yes | yes: 20 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | yes | yes: 16 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 10 |
| NetGPI | no | yes: 0, no: 10 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0032991 | protein-containing complex | 1 | 11 |
| GO:0033178 | proton-transporting two-sector ATPase complex, catalytic domain | 3 | 11 |
| GO:0045261 | proton-transporting ATP synthase complex, catalytic core F(1) | 4 | 11 |
| GO:0098796 | membrane protein complex | 2 | 11 |
| GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) | 4 | 1 |
| GO:0098798 | mitochondrial protein-containing complex | 2 | 1 |
| GO:0098800 | inner mitochondrial membrane protein complex | 3 | 1 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pescher et al. (upgregulation) | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
|
Lahav et al. - mRNA
- Protein
|
Related structures:
AlphaFold database: A4I651
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006139 | nucleobase-containing compound metabolic process | 3 | 1 |
| GO:0006163 | purine nucleotide metabolic process | 5 | 1 |
| GO:0006164 | purine nucleotide biosynthetic process | 6 | 1 |
| GO:0006725 | cellular aromatic compound metabolic process | 3 | 1 |
| GO:0006753 | nucleoside phosphate metabolic process | 4 | 1 |
| GO:0006754 | ATP biosynthetic process | 8 | 1 |
| GO:0006793 | phosphorus metabolic process | 3 | 1 |
| GO:0006796 | phosphate-containing compound metabolic process | 4 | 1 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 1 |
| GO:0008152 | metabolic process | 1 | 1 |
| GO:0009058 | biosynthetic process | 2 | 1 |
| GO:0009117 | nucleotide metabolic process | 5 | 1 |
| GO:0009141 | nucleoside triphosphate metabolic process | 5 | 1 |
| GO:0009142 | nucleoside triphosphate biosynthetic process | 6 | 1 |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 6 | 1 |
| GO:0009145 | purine nucleoside triphosphate biosynthetic process | 7 | 1 |
| GO:0009150 | purine ribonucleotide metabolic process | 6 | 1 |
| GO:0009152 | purine ribonucleotide biosynthetic process | 7 | 1 |
| GO:0009165 | nucleotide biosynthetic process | 6 | 1 |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 6 | 1 |
| GO:0009201 | ribonucleoside triphosphate biosynthetic process | 7 | 1 |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 7 | 1 |
| GO:0009206 | purine ribonucleoside triphosphate biosynthetic process | 8 | 1 |
| GO:0009259 | ribonucleotide metabolic process | 5 | 1 |
| GO:0009260 | ribonucleotide biosynthetic process | 6 | 1 |
| GO:0009987 | cellular process | 1 | 1 |
| GO:0015986 | proton motive force-driven ATP synthesis | 9 | 1 |
| GO:0018130 | heterocycle biosynthetic process | 4 | 1 |
| GO:0019438 | aromatic compound biosynthetic process | 4 | 1 |
| GO:0019637 | organophosphate metabolic process | 3 | 1 |
| GO:0019693 | ribose phosphate metabolic process | 4 | 1 |
| GO:0034641 | cellular nitrogen compound metabolic process | 3 | 1 |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 4 | 1 |
| GO:0044237 | cellular metabolic process | 2 | 1 |
| GO:0044238 | primary metabolic process | 2 | 1 |
| GO:0044249 | cellular biosynthetic process | 3 | 1 |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 4 | 1 |
| GO:0044281 | small molecule metabolic process | 2 | 1 |
| GO:0046034 | ATP metabolic process | 7 | 1 |
| GO:0046390 | ribose phosphate biosynthetic process | 5 | 1 |
| GO:0046483 | heterocycle metabolic process | 3 | 1 |
| GO:0055086 | nucleobase-containing small molecule metabolic process | 3 | 1 |
| GO:0071704 | organic substance metabolic process | 2 | 1 |
| GO:0072521 | purine-containing compound metabolic process | 4 | 1 |
| GO:0072522 | purine-containing compound biosynthetic process | 5 | 1 |
| GO:0090407 | organophosphate biosynthetic process | 4 | 1 |
| GO:1901135 | carbohydrate derivative metabolic process | 3 | 1 |
| GO:1901137 | carbohydrate derivative biosynthetic process | 4 | 1 |
| GO:1901293 | nucleoside phosphate biosynthetic process | 5 | 1 |
| GO:1901360 | organic cyclic compound metabolic process | 3 | 1 |
| GO:1901362 | organic cyclic compound biosynthetic process | 4 | 1 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 1 |
| GO:1901566 | organonitrogen compound biosynthetic process | 4 | 1 |
| GO:1901576 | organic substance biosynthetic process | 3 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003824 | catalytic activity | 1 | 11 |
| GO:0005215 | transporter activity | 1 | 11 |
| GO:0005216 | monoatomic ion channel activity | 4 | 11 |
| GO:0005261 | monoatomic cation channel activity | 5 | 11 |
| GO:0008324 | monoatomic cation transmembrane transporter activity | 4 | 11 |
| GO:0015075 | monoatomic ion transmembrane transporter activity | 3 | 11 |
| GO:0015078 | proton transmembrane transporter activity | 5 | 11 |
| GO:0015252 | proton channel activity | 6 | 11 |
| GO:0015267 | channel activity | 4 | 11 |
| GO:0015318 | inorganic molecular entity transmembrane transporter activity | 3 | 11 |
| GO:0016787 | hydrolase activity | 2 | 8 |
| GO:0016874 | ligase activity | 2 | 11 |
| GO:0022803 | passive transmembrane transporter activity | 3 | 11 |
| GO:0022857 | transmembrane transporter activity | 2 | 11 |
| GO:0022890 | inorganic cation transmembrane transporter activity | 4 | 11 |
| GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism | 3 | 11 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 99 | 103 | PF00656 | 0.284 |
| CLV_NRD_NRD_1 | 7 | 9 | PF00675 | 0.497 |
| CLV_PCSK_KEX2_1 | 7 | 9 | PF00082 | 0.497 |
| CLV_PCSK_PC7_1 | 3 | 9 | PF00082 | 0.495 |
| CLV_PCSK_SKI1_1 | 107 | 111 | PF00082 | 0.394 |
| CLV_PCSK_SKI1_1 | 67 | 71 | PF00082 | 0.284 |
| DEG_Nend_Nbox_1 | 1 | 3 | PF02207 | 0.498 |
| DOC_CKS1_1 | 90 | 95 | PF01111 | 0.351 |
| DOC_CYCLIN_RxL_1 | 7 | 19 | PF00134 | 0.542 |
| DOC_MAPK_gen_1 | 159 | 168 | PF00069 | 0.384 |
| DOC_MAPK_MEF2A_6 | 159 | 168 | PF00069 | 0.375 |
| DOC_USP7_MATH_1 | 151 | 155 | PF00917 | 0.447 |
| DOC_USP7_UBL2_3 | 33 | 37 | PF12436 | 0.449 |
| DOC_WW_Pin1_4 | 89 | 94 | PF00397 | 0.388 |
| LIG_14-3-3_CanoR_1 | 50 | 54 | PF00244 | 0.260 |
| LIG_Actin_WH2_2 | 163 | 181 | PF00022 | 0.431 |
| LIG_BRCT_BRCA1_1 | 110 | 114 | PF00533 | 0.284 |
| LIG_FHA_1 | 11 | 17 | PF00498 | 0.466 |
| LIG_FHA_1 | 46 | 52 | PF00498 | 0.357 |
| LIG_FHA_2 | 132 | 138 | PF00498 | 0.476 |
| LIG_FHA_2 | 52 | 58 | PF00498 | 0.284 |
| LIG_LIR_Gen_1 | 111 | 120 | PF02991 | 0.277 |
| LIG_LIR_Gen_1 | 19 | 27 | PF02991 | 0.488 |
| LIG_LIR_Gen_1 | 41 | 51 | PF02991 | 0.531 |
| LIG_LIR_Nem_3 | 111 | 117 | PF02991 | 0.284 |
| LIG_Rb_LxCxE_1 | 120 | 142 | PF01857 | 0.471 |
| LIG_SH2_GRB2like | 43 | 46 | PF00017 | 0.509 |
| LIG_SH2_STAT5 | 108 | 111 | PF00017 | 0.232 |
| LIG_SH3_3 | 95 | 101 | PF00018 | 0.362 |
| LIG_SUMO_SIM_par_1 | 94 | 99 | PF11976 | 0.284 |
| MOD_CK2_1 | 38 | 44 | PF00069 | 0.566 |
| MOD_Cter_Amidation | 5 | 8 | PF01082 | 0.514 |
| MOD_GlcNHglycan | 110 | 113 | PF01048 | 0.275 |
| MOD_GlcNHglycan | 149 | 152 | PF01048 | 0.420 |
| MOD_GlcNHglycan | 153 | 156 | PF01048 | 0.404 |
| MOD_GlcNHglycan | 40 | 43 | PF01048 | 0.605 |
| MOD_GSK3_1 | 147 | 154 | PF00069 | 0.567 |
| MOD_GSK3_1 | 170 | 177 | PF00069 | 0.421 |
| MOD_GSK3_1 | 45 | 52 | PF00069 | 0.394 |
| MOD_NEK2_1 | 49 | 54 | PF00069 | 0.284 |
| MOD_NEK2_2 | 101 | 106 | PF00069 | 0.382 |
| MOD_PIKK_1 | 86 | 92 | PF00454 | 0.378 |
| MOD_PKA_2 | 49 | 55 | PF00069 | 0.284 |
| MOD_Plk_1 | 86 | 92 | PF00069 | 0.347 |
| MOD_Plk_4 | 170 | 176 | PF00069 | 0.401 |
| MOD_Plk_4 | 67 | 73 | PF00069 | 0.430 |
| MOD_ProDKin_1 | 89 | 95 | PF00069 | 0.388 |
| MOD_SUMO_rev_2 | 154 | 160 | PF00179 | 0.416 |
| MOD_SUMO_rev_2 | 25 | 35 | PF00179 | 0.438 |
| TRG_DiLeu_BaEn_2 | 24 | 30 | PF01217 | 0.489 |
| TRG_DiLeu_BaLyEn_6 | 12 | 17 | PF01217 | 0.495 |
| TRG_ENDOCYTIC_2 | 20 | 23 | PF00928 | 0.490 |
| TRG_ENDOCYTIC_2 | 43 | 46 | PF00928 | 0.509 |
| TRG_ER_diArg_1 | 7 | 9 | PF00400 | 0.497 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1IHI5 | Leptomonas seymouri | 82% | 100% |
| A0A0S4JHX9 | Bodo saltans | 61% | 100% |
| A0A1X0P1V7 | Trypanosomatidae | 69% | 99% |
| A0A3R7L340 | Trypanosoma rangeli | 70% | 99% |
| A0A3S5H7P0 | Leishmania donovani | 100% | 100% |
| A1V8T0 | Burkholderia mallei (strain SAVP1) | 27% | 100% |
| A1VIV3 | Polaromonas naphthalenivorans (strain CJ2) | 29% | 100% |
| A2S6J7 | Burkholderia mallei (strain NCTC 10229) | 27% | 100% |
| A3MQK0 | Burkholderia mallei (strain NCTC 10247) | 27% | 100% |
| A3NF39 | Burkholderia pseudomallei (strain 668) | 27% | 100% |
| A3P0Y9 | Burkholderia pseudomallei (strain 1106a) | 27% | 100% |
| A4HIU6 | Leishmania braziliensis | 87% | 100% |
| A6Q4B9 | Nitratiruptor sp. (strain SB155-2) | 32% | 100% |
| A7HT53 | Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) | 30% | 100% |
| A9AJG5 | Burkholderia multivorans (strain ATCC 17616 / 249) | 27% | 100% |
| A9BPU8 | Delftia acidovorans (strain DSM 14801 / SPH-1) | 28% | 100% |
| B1YQL5 | Burkholderia ambifaria (strain MC40-6) | 27% | 100% |
| C0HK54 | Pichia angusta | 32% | 100% |
| C9ZRH1 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 69% | 99% |
| E9B1D4 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 96% | 100% |
| P05630 | Bos taurus | 31% | 100% |
| P0DPG2 | Trypanosoma brucei brucei | 68% | 99% |
| P30049 | Homo sapiens | 30% | 100% |
| P35434 | Rattus norvegicus | 32% | 100% |
| P56525 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 30% | 100% |
| P78700 | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) | 27% | 100% |
| Q09544 | Caenorhabditis elegans | 34% | 100% |
| Q0BJL4 | Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) | 27% | 100% |
| Q12165 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 28% | 100% |
| Q1BRB1 | Burkholderia cenocepacia (strain AU 1054) | 27% | 100% |
| Q39KX5 | Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) | 27% | 100% |
| Q3JXW0 | Burkholderia pseudomallei (strain 1710b) | 27% | 100% |
| Q40089 | Ipomoea batatas | 38% | 90% |
| Q4Q6S8 | Leishmania major | 98% | 100% |
| Q55F42 | Dictyostelium discoideum | 33% | 100% |
| Q62FR4 | Burkholderia mallei (strain ATCC 23344) | 27% | 100% |
| Q63PI1 | Burkholderia pseudomallei (strain K96243) | 27% | 100% |
| Q757N0 | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) | 32% | 100% |
| Q92196 | Agaricus bisporus | 29% | 100% |
| Q96252 | Arabidopsis thaliana | 39% | 89% |
| Q9D3D9 | Mus musculus | 33% | 100% |
| Q9P6R6 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 29% | 100% |