Putative 60S acidic ribosomal protein P2

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

60S acidic ribosomal protein P2 - putative

Species:

Leishmania infantum

UniProt:

A4I5Z9_LEIIN

TriTrypDb:

LINF_300043000

Length:

105

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 60S acidic ribosomal P2 LIP1

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

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Cellular components
Term	Name	Level	Count
GO:0015934	large ribosomal subunit	4	13
GO:0022625	cytosolic large ribosomal subunit	5	13
GO:0032991	protein-containing complex	1	13
GO:0044391	ribosomal subunit	3	13
GO:1990904	ribonucleoprotein complex	2	13

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Phosphorylation

Promastigote: 64, 74

Expansion

Sequence features

A4I5Z9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I5Z9

PDB structure(s): 1s4h_A

Function

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Biological processes
Term	Name	Level	Count
GO:0002182	cytoplasmic translational elongation	6	13
GO:0006414	translational elongation	5	13
GO:0008152	metabolic process	1	13
GO:0009058	biosynthetic process	2	13
GO:0009059	macromolecule biosynthetic process	4	13
GO:0009987	cellular process	1	13
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	13
GO:0043170	macromolecule metabolic process	3	13
GO:0044237	cellular metabolic process	2	13
GO:0044249	cellular biosynthetic process	3	13

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Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	13
GO:0005198	structural molecule activity	1	13

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	36	40	PF00656	0.507
DEG_Nend_UBRbox_3	1	3	PF02207	0.447
DOC_USP7_MATH_1	71	75	PF00917	0.499
DOC_USP7_UBL2_3	15	19	PF12436	0.303
DOC_WW_Pin1_4	13	18	PF00397	0.440
LIG_LIR_Gen_1	39	50	PF02991	0.452
LIG_LIR_Nem_3	39	45	PF02991	0.440
LIG_LIR_Nem_3	49	53	PF02991	0.455
LIG_LIR_Nem_3	98	104	PF02991	0.480
LIG_SH2_CRK	7	11	PF00017	0.343

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZR2	Leptomonas seymouri	76%	98%
A0A0S4JJB8	Bodo saltans	45%	97%
A0A1X0P2R9	Trypanosomatidae	68%	100%
A0A3Q8ICC2	Leishmania donovani	53%	95%
A0A3Q8IG52	Leishmania donovani	99%	100%
A0A422NR90	Trypanosoma rangeli	48%	95%
A4H884	Leishmania braziliensis	50%	100%
A4I600	Leishmania infantum	99%	100%
C9ZRI4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	64%	98%
E9AGM1	Leishmania infantum	52%	95%

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