LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I5M2_LEIIN
TriTrypDb:
LINF_300024400
Length:
440

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I5M2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I5M2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 144 146 PF00675 0.633
CLV_NRD_NRD_1 241 243 PF00675 0.506
CLV_NRD_NRD_1 344 346 PF00675 0.558
CLV_NRD_NRD_1 395 397 PF00675 0.510
CLV_PCSK_KEX2_1 144 146 PF00082 0.726
CLV_PCSK_KEX2_1 241 243 PF00082 0.516
CLV_PCSK_KEX2_1 288 290 PF00082 0.547
CLV_PCSK_PC1ET2_1 288 290 PF00082 0.547
CLV_PCSK_SKI1_1 201 205 PF00082 0.564
CLV_PCSK_SKI1_1 24 28 PF00082 0.483
CLV_PCSK_SKI1_1 365 369 PF00082 0.670
CLV_PCSK_SKI1_1 423 427 PF00082 0.555
CLV_PCSK_SKI1_1 47 51 PF00082 0.505
CLV_PCSK_SKI1_1 64 68 PF00082 0.482
CLV_PCSK_SKI1_1 73 77 PF00082 0.436
DEG_APCC_DBOX_1 340 348 PF00400 0.612
DOC_CDC14_PxL_1 33 41 PF14671 0.489
DOC_CYCLIN_RxL_1 420 429 PF00134 0.671
DOC_MAPK_gen_1 226 233 PF00069 0.477
DOC_MAPK_gen_1 288 296 PF00069 0.447
DOC_MAPK_MEF2A_6 376 384 PF00069 0.640
DOC_MAPK_MEF2A_6 423 432 PF00069 0.698
DOC_PP1_RVXF_1 22 28 PF00149 0.510
DOC_USP7_MATH_1 287 291 PF00917 0.471
DOC_USP7_MATH_1 88 92 PF00917 0.598
DOC_USP7_UBL2_3 184 188 PF12436 0.394
DOC_WW_Pin1_4 147 152 PF00397 0.702
DOC_WW_Pin1_4 3 8 PF00397 0.755
DOC_WW_Pin1_4 352 357 PF00397 0.612
LIG_14-3-3_CanoR_1 144 151 PF00244 0.699
LIG_14-3-3_CanoR_1 201 210 PF00244 0.589
LIG_14-3-3_CanoR_1 242 252 PF00244 0.587
LIG_14-3-3_CanoR_1 365 375 PF00244 0.649
LIG_14-3-3_CanoR_1 388 392 PF00244 0.524
LIG_14-3-3_CanoR_1 396 400 PF00244 0.590
LIG_14-3-3_CanoR_1 73 79 PF00244 0.553
LIG_14-3-3_CanoR_1 89 93 PF00244 0.470
LIG_BIR_II_1 1 5 PF00653 0.643
LIG_BRCT_BRCA1_1 260 264 PF00533 0.293
LIG_deltaCOP1_diTrp_1 209 214 PF00928 0.588
LIG_FHA_1 202 208 PF00498 0.462
LIG_FHA_1 244 250 PF00498 0.596
LIG_FHA_1 296 302 PF00498 0.523
LIG_FHA_1 349 355 PF00498 0.699
LIG_FHA_1 95 101 PF00498 0.511
LIG_FHA_2 107 113 PF00498 0.577
LIG_FHA_2 124 130 PF00498 0.600
LIG_FHA_2 137 143 PF00498 0.697
LIG_FHA_2 422 428 PF00498 0.583
LIG_FHA_2 55 61 PF00498 0.583
LIG_LIR_Gen_1 176 185 PF02991 0.433
LIG_LIR_Gen_1 45 53 PF02991 0.500
LIG_LIR_Nem_3 176 182 PF02991 0.435
LIG_LIR_Nem_3 261 267 PF02991 0.475
LIG_LIR_Nem_3 45 51 PF02991 0.497
LIG_LIR_Nem_3 74 78 PF02991 0.487
LIG_SH2_CRK 48 52 PF00017 0.530
LIG_SH2_NCK_1 179 183 PF00017 0.553
LIG_SH2_SRC 179 182 PF00017 0.397
LIG_SH2_SRC 28 31 PF00017 0.615
LIG_SH2_SRC 299 302 PF00017 0.445
LIG_SH2_STAP1 179 183 PF00017 0.433
LIG_SH2_STAP1 28 32 PF00017 0.538
LIG_SH2_STAP1 292 296 PF00017 0.541
LIG_SH2_STAT3 303 306 PF00017 0.482
LIG_SUMO_SIM_anti_2 152 161 PF11976 0.576
LIG_SUMO_SIM_anti_2 326 331 PF11976 0.492
LIG_SUMO_SIM_par_1 152 161 PF11976 0.555
LIG_SUMO_SIM_par_1 350 355 PF11976 0.665
LIG_TRAF2_1 254 257 PF00917 0.492
LIG_TRAF2_1 91 94 PF00917 0.543
LIG_UBA3_1 249 253 PF00899 0.375
LIG_UBA3_1 39 47 PF00899 0.535
LIG_WRC_WIRS_1 50 55 PF05994 0.558
MOD_CDK_SPK_2 3 8 PF00069 0.677
MOD_CDK_SPxK_1 352 358 PF00069 0.691
MOD_CK1_1 147 153 PF00069 0.603
MOD_CK1_1 2 8 PF00069 0.734
MOD_CK1_1 54 60 PF00069 0.528
MOD_CK1_1 81 87 PF00069 0.549
MOD_CK1_1 9 15 PF00069 0.715
MOD_CK2_1 106 112 PF00069 0.496
MOD_CK2_1 123 129 PF00069 0.645
MOD_CK2_1 136 142 PF00069 0.590
MOD_CK2_1 287 293 PF00069 0.501
MOD_CK2_1 309 315 PF00069 0.504
MOD_CK2_1 387 393 PF00069 0.635
MOD_CK2_1 421 427 PF00069 0.607
MOD_CK2_1 49 55 PF00069 0.571
MOD_CK2_1 88 94 PF00069 0.510
MOD_GlcNHglycan 109 112 PF01048 0.553
MOD_GlcNHglycan 117 120 PF01048 0.562
MOD_GlcNHglycan 134 137 PF01048 0.657
MOD_GlcNHglycan 146 149 PF01048 0.527
MOD_GlcNHglycan 175 178 PF01048 0.607
MOD_GlcNHglycan 222 225 PF01048 0.412
MOD_GlcNHglycan 404 407 PF01048 0.690
MOD_GlcNHglycan 414 418 PF01048 0.560
MOD_GlcNHglycan 44 47 PF01048 0.481
MOD_GlcNHglycan 64 67 PF01048 0.289
MOD_GSK3_1 103 110 PF00069 0.598
MOD_GSK3_1 132 139 PF00069 0.702
MOD_GSK3_1 2 9 PF00069 0.763
MOD_GSK3_1 348 355 PF00069 0.573
MOD_GSK3_1 409 416 PF00069 0.577
MOD_GSK3_1 67 74 PF00069 0.565
MOD_N-GLC_1 132 137 PF02516 0.708
MOD_N-GLC_1 79 84 PF02516 0.584
MOD_NEK2_1 11 16 PF00069 0.688
MOD_NEK2_1 114 119 PF00069 0.621
MOD_NEK2_1 319 324 PF00069 0.592
MOD_NEK2_1 348 353 PF00069 0.499
MOD_NEK2_1 380 385 PF00069 0.617
MOD_NEK2_1 402 407 PF00069 0.586
MOD_NEK2_1 67 72 PF00069 0.595
MOD_NEK2_1 78 83 PF00069 0.486
MOD_PIKK_1 258 264 PF00454 0.374
MOD_PKA_1 144 150 PF00069 0.626
MOD_PKA_2 144 150 PF00069 0.670
MOD_PKA_2 387 393 PF00069 0.597
MOD_PKA_2 395 401 PF00069 0.566
MOD_PKA_2 88 94 PF00069 0.567
MOD_Plk_1 20 26 PF00069 0.559
MOD_Plk_1 363 369 PF00069 0.693
MOD_Plk_1 54 60 PF00069 0.409
MOD_Plk_1 9 15 PF00069 0.575
MOD_Plk_2-3 309 315 PF00069 0.504
MOD_Plk_4 103 109 PF00069 0.614
MOD_Plk_4 35 41 PF00069 0.463
MOD_Plk_4 380 386 PF00069 0.528
MOD_Plk_4 81 87 PF00069 0.617
MOD_ProDKin_1 147 153 PF00069 0.699
MOD_ProDKin_1 3 9 PF00069 0.754
MOD_ProDKin_1 352 358 PF00069 0.616
MOD_SUMO_for_1 281 284 PF00179 0.602
MOD_SUMO_rev_2 91 100 PF00179 0.552
TRG_DiLeu_BaEn_1 315 320 PF01217 0.607
TRG_ENDOCYTIC_2 179 182 PF00928 0.556
TRG_ENDOCYTIC_2 28 31 PF00928 0.573
TRG_ENDOCYTIC_2 48 51 PF00928 0.507
TRG_ER_diArg_1 143 145 PF00400 0.649
TRG_ER_diArg_1 289 292 PF00400 0.588
TRG_NLS_MonoExtC_3 287 293 PF00514 0.587
TRG_Pf-PMV_PEXEL_1 365 370 PF00026 0.695
TRG_Pf-PMV_PEXEL_1 423 427 PF00026 0.630

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PDD9 Leptomonas seymouri 59% 100%
A0A1X0P1Q4 Trypanosomatidae 37% 95%
A0A3S5H7N1 Leishmania donovani 99% 100%
A0A3S5ISM8 Trypanosoma rangeli 34% 93%
A4HIC9 Leishmania braziliensis 76% 100%
E9B0W7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4Q799 Leishmania major 91% 100%
V5B8X3 Trypanosoma cruzi 34% 93%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS