Flagellar basal body L-ring protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I5K2_LEIIN

TriTrypDb:

LINF_300022400

Length:

115

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4I5K2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I5K2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	32	36	PF00656	0.569
CLV_NRD_NRD_1	6	8	PF00675	0.504
CLV_NRD_NRD_1	88	90	PF00675	0.486
CLV_PCSK_FUR_1	25	29	PF00082	0.674
CLV_PCSK_KEX2_1	18	20	PF00082	0.555
CLV_PCSK_KEX2_1	27	29	PF00082	0.601
CLV_PCSK_PC1ET2_1	18	20	PF00082	0.555
CLV_PCSK_PC1ET2_1	27	29	PF00082	0.601
CLV_PCSK_SKI1_1	103	107	PF00082	0.472
DEG_Nend_Nbox_1	1	3	PF02207	0.386
DEG_SCF_SKP2-CKS1_1	58	65	PF00560	0.405
DOC_CKS1_1	44	49	PF01111	0.623
DOC_USP7_UBL2_3	103	107	PF12436	0.423
DOC_USP7_UBL2_3	18	22	PF12436	0.558
DOC_USP7_UBL2_3	90	94	PF12436	0.472
DOC_WW_Pin1_4	43	48	PF00397	0.684
DOC_WW_Pin1_4	59	64	PF00397	0.415
LIG_14-3-3_CanoR_1	25	34	PF00244	0.662
LIG_FHA_1	47	53	PF00498	0.516
LIG_LIR_Gen_1	81	87	PF02991	0.441
LIG_LIR_Nem_3	81	86	PF02991	0.440
LIG_NRP_CendR_1	112	115	PF00754	0.495
LIG_PCNA_yPIPBox_3	37	48	PF02747	0.483
LIG_SH2_CRK	10	14	PF00017	0.460
LIG_SH2_PTP2	83	86	PF00017	0.435
LIG_SH2_SRC	83	86	PF00017	0.435
LIG_SH2_STAT5	2	5	PF00017	0.457
LIG_SH2_STAT5	61	64	PF00017	0.517
LIG_SH2_STAT5	83	86	PF00017	0.435
LIG_SH3_3	41	47	PF00018	0.619
LIG_SUMO_SIM_anti_2	72	78	PF11976	0.424
MOD_CDK_SPK_2	43	48	PF00069	0.567
MOD_CDK_SPxK_1	59	65	PF00069	0.398
MOD_CK1_1	29	35	PF00069	0.574
MOD_CK1_1	36	42	PF00069	0.570
MOD_GlcNHglycan	29	32	PF01048	0.576
MOD_GSK3_1	13	20	PF00069	0.609
MOD_GSK3_1	29	36	PF00069	0.523
MOD_GSK3_1	42	49	PF00069	0.614
MOD_GSK3_1	55	62	PF00069	0.466
MOD_N-GLC_1	36	41	PF02516	0.558
MOD_NEK2_1	13	18	PF00069	0.656
MOD_PK_1	94	100	PF00069	0.510
MOD_PKA_1	18	24	PF00069	0.614
MOD_PKA_1	27	33	PF00069	0.545
MOD_PKA_2	18	24	PF00069	0.614
MOD_PKA_2	27	33	PF00069	0.545
MOD_Plk_1	36	42	PF00069	0.649
MOD_ProDKin_1	43	49	PF00069	0.682
MOD_ProDKin_1	59	65	PF00069	0.411
MOD_SUMO_rev_2	85	92	PF00179	0.468
MOD_SUMO_rev_2	97	105	PF00179	0.439
TRG_DiLeu_BaEn_1	101	106	PF01217	0.436
TRG_ENDOCYTIC_2	10	13	PF00928	0.499
TRG_ENDOCYTIC_2	2	5	PF00928	0.457
TRG_ENDOCYTIC_2	83	86	PF00928	0.435

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1P9Q9	Leptomonas seymouri	67%	69%
A0A3Q8IFM8	Leishmania donovani	98%	70%
A4HIB8	Leishmania braziliensis	78%	100%
E9B0U7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4Q7B9	Leishmania major	91%	100%