PSP1 C-terminal domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PSP1 C-terminal conserved region containing protein - putative

Species:

Leishmania infantum

UniProt:

A4I5G8_LEIIN

TriTrypDb:

LINF_300019300

Length:

1059

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I5G8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I5G8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	104	108	PF00656	0.593
CLV_C14_Caspase3-7	360	364	PF00656	0.639
CLV_C14_Caspase3-7	865	869	PF00656	0.638
CLV_NRD_NRD_1	383	385	PF00675	0.836
CLV_NRD_NRD_1	475	477	PF00675	0.689
CLV_NRD_NRD_1	652	654	PF00675	0.706
CLV_NRD_NRD_1	673	675	PF00675	0.572
CLV_NRD_NRD_1	732	734	PF00675	0.718
CLV_NRD_NRD_1	799	801	PF00675	0.740
CLV_NRD_NRD_1	949	951	PF00675	0.726
CLV_NRD_NRD_1	960	962	PF00675	0.509
CLV_PCSK_KEX2_1	1046	1048	PF00082	0.537
CLV_PCSK_KEX2_1	382	384	PF00082	0.841
CLV_PCSK_KEX2_1	475	477	PF00082	0.689
CLV_PCSK_KEX2_1	652	654	PF00082	0.706
CLV_PCSK_KEX2_1	673	675	PF00082	0.572
CLV_PCSK_KEX2_1	732	734	PF00082	0.718
CLV_PCSK_KEX2_1	799	801	PF00082	0.740
CLV_PCSK_KEX2_1	878	880	PF00082	0.762
CLV_PCSK_PC1ET2_1	1046	1048	PF00082	0.537
CLV_PCSK_PC1ET2_1	878	880	PF00082	0.762
CLV_PCSK_PC7_1	1042	1048	PF00082	0.450
CLV_PCSK_SKI1_1	1033	1037	PF00082	0.448
CLV_PCSK_SKI1_1	1042	1046	PF00082	0.369
CLV_PCSK_SKI1_1	26	30	PF00082	0.518
CLV_PCSK_SKI1_1	853	857	PF00082	0.702
CLV_PCSK_SKI1_1	892	896	PF00082	0.681
CLV_PCSK_SKI1_1	966	970	PF00082	0.511
CLV_PCSK_SKI1_1	980	984	PF00082	0.300
CLV_Separin_Metazoa	356	360	PF03568	0.623
DEG_APCC_DBOX_1	891	899	PF00400	0.667
DEG_APCC_KENBOX_2	36	40	PF00400	0.581
DEG_SCF_FBW7_1	342	347	PF00400	0.675
DEG_SCF_FBW7_1	929	935	PF00400	0.575
DEG_SPOP_SBC_1	581	585	PF00917	0.761
DEG_SPOP_SBC_1	775	779	PF00917	0.677
DOC_CKS1_1	148	153	PF01111	0.595
DOC_CKS1_1	206	211	PF01111	0.756
DOC_CKS1_1	276	281	PF01111	0.789
DOC_CKS1_1	303	308	PF01111	0.735
DOC_CKS1_1	457	462	PF01111	0.799
DOC_CKS1_1	929	934	PF01111	0.567
DOC_CYCLIN_RxL_1	889	899	PF00134	0.735
DOC_CYCLIN_RxL_1	961	973	PF00134	0.394
DOC_CYCLIN_yCln2_LP_2	237	243	PF00134	0.786
DOC_CYCLIN_yCln2_LP_2	407	410	PF00134	0.722
DOC_MAPK_gen_1	732	742	PF00069	0.721
DOC_MAPK_gen_1	950	956	PF00069	0.450
DOC_MAPK_gen_1	961	969	PF00069	0.450
DOC_MAPK_gen_1	980	989	PF00069	0.411
DOC_PP1_RVXF_1	1031	1038	PF00149	0.411
DOC_PP2B_LxvP_1	241	244	PF13499	0.728
DOC_PP2B_LxvP_1	407	410	PF13499	0.722
DOC_PP2B_LxvP_1	441	444	PF13499	0.632
DOC_PP2B_LxvP_1	691	694	PF13499	0.739
DOC_PP4_FxxP_1	123	126	PF00568	0.600
DOC_PP4_FxxP_1	206	209	PF00568	0.611
DOC_PP4_FxxP_1	324	327	PF00568	0.683
DOC_USP7_MATH_1	1013	1017	PF00917	0.462
DOC_USP7_MATH_1	1026	1030	PF00917	0.298
DOC_USP7_MATH_1	187	191	PF00917	0.789
DOC_USP7_MATH_1	195	199	PF00917	0.605
DOC_USP7_MATH_1	270	274	PF00917	0.743
DOC_USP7_MATH_1	282	286	PF00917	0.601
DOC_USP7_MATH_1	294	298	PF00917	0.689
DOC_USP7_MATH_1	368	372	PF00917	0.729
DOC_USP7_MATH_1	378	382	PF00917	0.676
DOC_USP7_MATH_1	403	407	PF00917	0.688
DOC_USP7_MATH_1	489	493	PF00917	0.728
DOC_USP7_MATH_1	523	527	PF00917	0.723
DOC_USP7_MATH_1	528	532	PF00917	0.692
DOC_USP7_MATH_1	663	667	PF00917	0.615
DOC_USP7_MATH_1	704	708	PF00917	0.753
DOC_USP7_MATH_1	775	779	PF00917	0.719
DOC_USP7_MATH_1	9	13	PF00917	0.609
DOC_USP7_MATH_1	92	96	PF00917	0.524
DOC_USP7_MATH_1	932	936	PF00917	0.479
DOC_USP7_MATH_2	166	172	PF00917	0.603
DOC_USP7_MATH_2	914	920	PF00917	0.626
DOC_WW_Pin1_4	128	133	PF00397	0.587
DOC_WW_Pin1_4	144	149	PF00397	0.794
DOC_WW_Pin1_4	175	180	PF00397	0.798
DOC_WW_Pin1_4	205	210	PF00397	0.706
DOC_WW_Pin1_4	217	222	PF00397	0.751
DOC_WW_Pin1_4	236	241	PF00397	0.539
DOC_WW_Pin1_4	275	280	PF00397	0.703
DOC_WW_Pin1_4	302	307	PF00397	0.685
DOC_WW_Pin1_4	323	328	PF00397	0.702
DOC_WW_Pin1_4	340	345	PF00397	0.687
DOC_WW_Pin1_4	363	368	PF00397	0.668
DOC_WW_Pin1_4	374	379	PF00397	0.716
DOC_WW_Pin1_4	434	439	PF00397	0.683
DOC_WW_Pin1_4	456	461	PF00397	0.697
DOC_WW_Pin1_4	68	73	PF00397	0.598
DOC_WW_Pin1_4	715	720	PF00397	0.683
DOC_WW_Pin1_4	88	93	PF00397	0.464
DOC_WW_Pin1_4	910	915	PF00397	0.595
DOC_WW_Pin1_4	928	933	PF00397	0.552
LIG_14-3-3_CanoR_1	1024	1032	PF00244	0.522
LIG_14-3-3_CanoR_1	204	209	PF00244	0.775
LIG_14-3-3_CanoR_1	233	237	PF00244	0.732
LIG_14-3-3_CanoR_1	440	444	PF00244	0.796
LIG_14-3-3_CanoR_1	464	470	PF00244	0.743
LIG_14-3-3_CanoR_1	582	590	PF00244	0.741
LIG_14-3-3_CanoR_1	593	600	PF00244	0.640
LIG_14-3-3_CanoR_1	761	766	PF00244	0.816
LIG_14-3-3_CanoR_1	810	818	PF00244	0.738
LIG_Actin_WH2_2	937	952	PF00022	0.706
LIG_BIR_III_4	372	376	PF00653	0.650
LIG_BRCT_BRCA1_1	591	595	PF00533	0.693
LIG_FHA_1	254	260	PF00498	0.784
LIG_FHA_1	303	309	PF00498	0.591
LIG_FHA_1	345	351	PF00498	0.673
LIG_FHA_1	482	488	PF00498	0.698
LIG_FHA_1	884	890	PF00498	0.767
LIG_FHA_1	971	977	PF00498	0.443
LIG_FHA_2	218	224	PF00498	0.662
LIG_FHA_2	305	311	PF00498	0.693
LIG_FHA_2	375	381	PF00498	0.613
LIG_FHA_2	780	786	PF00498	0.730
LIG_FHA_2	863	869	PF00498	0.688
LIG_FHA_2	98	104	PF00498	0.597
LIG_LIR_Apic_2	321	327	PF02991	0.683
LIG_LIR_Gen_1	777	788	PF02991	0.795
LIG_LIR_Gen_1	919	927	PF02991	0.597
LIG_LIR_Gen_1	934	944	PF02991	0.503
LIG_LIR_Gen_1	992	1002	PF02991	0.394
LIG_LIR_Nem_3	23	28	PF02991	0.500
LIG_LIR_Nem_3	343	348	PF02991	0.784
LIG_LIR_Nem_3	777	783	PF02991	0.786
LIG_LIR_Nem_3	919	923	PF02991	0.612
LIG_LIR_Nem_3	934	940	PF02991	0.482
LIG_LIR_Nem_3	992	998	PF02991	0.352
LIG_PCNA_yPIPBox_3	351	359	PF02747	0.636
LIG_Pex14_2	316	320	PF04695	0.783
LIG_PTB_Apo_2	314	321	PF02174	0.670
LIG_Rb_LxCxE_1	891	913	PF01857	0.641
LIG_SH2_CRK	1007	1011	PF00017	0.411
LIG_SH2_CRK	780	784	PF00017	0.622
LIG_SH2_CRK	937	941	PF00017	0.601
LIG_SH2_GRB2like	32	35	PF00017	0.527
LIG_SH2_NCK_1	615	619	PF00017	0.759
LIG_SH2_NCK_1	630	634	PF00017	0.766
LIG_SH2_NCK_1	920	924	PF00017	0.687
LIG_SH2_SRC	242	245	PF00017	0.727
LIG_SH2_SRC	32	35	PF00017	0.527
LIG_SH2_SRC	630	633	PF00017	0.713
LIG_SH2_SRC	909	912	PF00017	0.604
LIG_SH2_SRC	920	923	PF00017	0.694
LIG_SH2_STAP1	348	352	PF00017	0.691
LIG_SH2_STAP1	615	619	PF00017	0.720
LIG_SH2_STAP1	768	772	PF00017	0.555
LIG_SH2_STAP1	937	941	PF00017	0.663
LIG_SH2_STAT3	348	351	PF00017	0.759
LIG_SH2_STAT5	32	35	PF00017	0.548
LIG_SH2_STAT5	481	484	PF00017	0.703
LIG_SH2_STAT5	904	907	PF00017	0.490
LIG_SH2_STAT5	975	978	PF00017	0.407
LIG_SH2_STAT5	995	998	PF00017	0.183
LIG_SH3_2	756	761	PF14604	0.747
LIG_SH3_3	129	135	PF00018	0.591
LIG_SH3_3	145	151	PF00018	0.788
LIG_SH3_3	420	426	PF00018	0.777
LIG_SH3_3	562	568	PF00018	0.769
LIG_SH3_3	723	729	PF00018	0.692
LIG_SH3_3	739	745	PF00018	0.592
LIG_SH3_3	753	759	PF00018	0.760
LIG_SUMO_SIM_anti_2	839	845	PF11976	0.615
LIG_SUMO_SIM_par_1	1008	1014	PF11976	0.306
LIG_SUMO_SIM_par_1	681	688	PF11976	0.722
LIG_SUMO_SIM_par_1	738	743	PF11976	0.718
LIG_SUMO_SIM_par_1	819	825	PF11976	0.766
LIG_TRAF2_1	353	356	PF00917	0.615
LIG_TYR_ITIM	1005	1010	PF00017	0.411
LIG_TYR_ITIM	918	923	PF00017	0.586
LIG_WRC_WIRS_1	362	367	PF05994	0.722
LIG_WRC_WIRS_1	995	1000	PF05994	0.352
LIG_WW_1	612	615	PF00397	0.706
MOD_CDK_SPK_2	147	152	PF00069	0.597
MOD_CDK_SPxK_1	275	281	PF00069	0.646
MOD_CDK_SPxK_1	363	369	PF00069	0.672
MOD_CDK_SPxK_1	434	440	PF00069	0.687
MOD_CDK_SPxxK_3	147	154	PF00069	0.598
MOD_CDK_SPxxK_3	205	212	PF00069	0.610
MOD_CK1_1	1016	1022	PF00069	0.450
MOD_CK1_1	167	173	PF00069	0.701
MOD_CK1_1	190	196	PF00069	0.731
MOD_CK1_1	211	217	PF00069	0.826
MOD_CK1_1	271	277	PF00069	0.744
MOD_CK1_1	319	325	PF00069	0.698
MOD_CK1_1	371	377	PF00069	0.690
MOD_CK1_1	48	54	PF00069	0.587
MOD_CK1_1	509	515	PF00069	0.689
MOD_CK1_1	580	586	PF00069	0.826
MOD_CK1_1	636	642	PF00069	0.757
MOD_CK1_1	68	74	PF00069	0.475
MOD_CK1_1	692	698	PF00069	0.633
MOD_CK1_1	718	724	PF00069	0.697
MOD_CK1_1	779	785	PF00069	0.699
MOD_CK1_1	877	883	PF00069	0.665
MOD_CK2_1	212	218	PF00069	0.767
MOD_CK2_1	319	325	PF00069	0.635
MOD_CK2_1	374	380	PF00069	0.611
MOD_CK2_1	448	454	PF00069	0.690
MOD_CK2_1	533	539	PF00069	0.790
MOD_CK2_1	779	785	PF00069	0.725
MOD_CK2_1	910	916	PF00069	0.688
MOD_CK2_1	97	103	PF00069	0.598
MOD_Cter_Amidation	671	674	PF01082	0.600
MOD_GlcNHglycan	1014	1018	PF01048	0.392
MOD_GlcNHglycan	11	14	PF01048	0.598
MOD_GlcNHglycan	132	135	PF01048	0.701
MOD_GlcNHglycan	156	159	PF01048	0.810
MOD_GlcNHglycan	192	195	PF01048	0.833
MOD_GlcNHglycan	213	217	PF01048	0.724
MOD_GlcNHglycan	255	259	PF01048	0.740
MOD_GlcNHglycan	264	267	PF01048	0.759
MOD_GlcNHglycan	284	287	PF01048	0.570
MOD_GlcNHglycan	296	299	PF01048	0.771
MOD_GlcNHglycan	321	324	PF01048	0.702
MOD_GlcNHglycan	372	376	PF01048	0.738
MOD_GlcNHglycan	410	413	PF01048	0.711
MOD_GlcNHglycan	470	473	PF01048	0.659
MOD_GlcNHglycan	50	53	PF01048	0.741
MOD_GlcNHglycan	513	516	PF01048	0.662
MOD_GlcNHglycan	535	538	PF01048	0.688
MOD_GlcNHglycan	57	60	PF01048	0.673
MOD_GlcNHglycan	579	582	PF01048	0.749
MOD_GlcNHglycan	636	639	PF01048	0.660
MOD_GlcNHglycan	67	70	PF01048	0.551
MOD_GlcNHglycan	691	694	PF01048	0.660
MOD_GlcNHglycan	720	723	PF01048	0.802
MOD_GlcNHglycan	75	78	PF01048	0.510
MOD_GlcNHglycan	763	766	PF01048	0.810
MOD_GlcNHglycan	796	799	PF01048	0.685
MOD_GlcNHglycan	812	815	PF01048	0.607
MOD_GlcNHglycan	824	827	PF01048	0.651
MOD_GlcNHglycan	984	987	PF01048	0.460
MOD_GSK3_1	1015	1022	PF00069	0.434
MOD_GSK3_1	1049	1056	PF00069	0.716
MOD_GSK3_1	110	117	PF00069	0.478
MOD_GSK3_1	126	133	PF00069	0.596
MOD_GSK3_1	164	171	PF00069	0.756
MOD_GSK3_1	204	211	PF00069	0.817
MOD_GSK3_1	232	239	PF00069	0.741
MOD_GSK3_1	264	271	PF00069	0.767
MOD_GSK3_1	290	297	PF00069	0.735
MOD_GSK3_1	298	305	PF00069	0.671
MOD_GSK3_1	319	326	PF00069	0.770
MOD_GSK3_1	340	347	PF00069	0.640
MOD_GSK3_1	357	364	PF00069	0.635
MOD_GSK3_1	374	381	PF00069	0.729
MOD_GSK3_1	455	462	PF00069	0.699
MOD_GSK3_1	481	488	PF00069	0.618
MOD_GSK3_1	529	536	PF00069	0.781
MOD_GSK3_1	573	580	PF00069	0.774
MOD_GSK3_1	589	596	PF00069	0.548
MOD_GSK3_1	633	640	PF00069	0.748
MOD_GSK3_1	689	696	PF00069	0.748
MOD_GSK3_1	700	707	PF00069	0.627
MOD_GSK3_1	775	782	PF00069	0.737
MOD_GSK3_1	873	880	PF00069	0.559
MOD_GSK3_1	88	95	PF00069	0.601
MOD_GSK3_1	884	891	PF00069	0.755
MOD_GSK3_1	9	16	PF00069	0.677
MOD_GSK3_1	928	935	PF00069	0.476
MOD_GSK3_1	97	104	PF00069	0.602
MOD_GSK3_1	990	997	PF00069	0.400
MOD_LATS_1	210	216	PF00433	0.615
MOD_N-GLC_1	190	195	PF02516	0.797
MOD_N-GLC_1	262	267	PF02516	0.818
MOD_N-GLC_1	316	321	PF02516	0.670
MOD_N-GLC_1	490	495	PF02516	0.634
MOD_N-GLC_1	856	861	PF02516	0.637
MOD_N-GLC_2	544	546	PF02516	0.567
MOD_NEK2_1	1049	1054	PF00069	0.633
MOD_NEK2_1	173	178	PF00069	0.826
MOD_NEK2_1	45	50	PF00069	0.595
MOD_NEK2_1	874	879	PF00069	0.728
MOD_NEK2_1	888	893	PF00069	0.647
MOD_NEK2_1	969	974	PF00069	0.403
MOD_NEK2_1	97	102	PF00069	0.555
MOD_NEK2_1	982	987	PF00069	0.431
MOD_NEK2_1	998	1003	PF00069	0.311
MOD_NEK2_2	932	937	PF00069	0.592
MOD_PIKK_1	1053	1059	PF00454	0.685
MOD_PIKK_1	196	202	PF00454	0.814
MOD_PIKK_1	264	270	PF00454	0.715
MOD_PIKK_1	804	810	PF00454	0.791
MOD_PKA_1	878	884	PF00069	0.783
MOD_PKA_2	196	202	PF00069	0.814
MOD_PKA_2	232	238	PF00069	0.731
MOD_PKA_2	387	393	PF00069	0.655
MOD_PKA_2	439	445	PF00069	0.798
MOD_PKA_2	463	469	PF00069	0.744
MOD_PKA_2	581	587	PF00069	0.746
MOD_PKA_2	809	815	PF00069	0.740
MOD_PKA_2	878	884	PF00069	0.783
MOD_PKB_1	202	210	PF00069	0.773
MOD_Plk_1	167	173	PF00069	0.672
MOD_Plk_1	316	322	PF00069	0.700
MOD_Plk_2-3	304	310	PF00069	0.590
MOD_Plk_2-3	916	922	PF00069	0.640
MOD_Plk_4	168	174	PF00069	0.636
MOD_Plk_4	232	238	PF00069	0.628
MOD_Plk_4	271	277	PF00069	0.799
MOD_Plk_4	304	310	PF00069	0.680
MOD_Plk_4	403	409	PF00069	0.677
MOD_Plk_4	551	557	PF00069	0.613
MOD_Plk_4	663	669	PF00069	0.591
MOD_Plk_4	884	890	PF00069	0.729
MOD_Plk_4	932	938	PF00069	0.595
MOD_Plk_4	990	996	PF00069	0.411
MOD_ProDKin_1	128	134	PF00069	0.589
MOD_ProDKin_1	144	150	PF00069	0.791
MOD_ProDKin_1	175	181	PF00069	0.798
MOD_ProDKin_1	205	211	PF00069	0.706
MOD_ProDKin_1	217	223	PF00069	0.748
MOD_ProDKin_1	236	242	PF00069	0.541
MOD_ProDKin_1	275	281	PF00069	0.703
MOD_ProDKin_1	302	308	PF00069	0.683
MOD_ProDKin_1	323	329	PF00069	0.701
MOD_ProDKin_1	340	346	PF00069	0.687
MOD_ProDKin_1	363	369	PF00069	0.672
MOD_ProDKin_1	374	380	PF00069	0.716
MOD_ProDKin_1	434	440	PF00069	0.687
MOD_ProDKin_1	456	462	PF00069	0.698
MOD_ProDKin_1	68	74	PF00069	0.598
MOD_ProDKin_1	715	721	PF00069	0.684
MOD_ProDKin_1	88	94	PF00069	0.465
MOD_ProDKin_1	910	916	PF00069	0.598
MOD_ProDKin_1	928	934	PF00069	0.548
MOD_SUMO_rev_2	1029	1037	PF00179	0.450
TRG_DiLeu_BaEn_1	168	173	PF01217	0.757
TRG_DiLeu_BaLyEn_6	1005	1010	PF01217	0.434
TRG_DiLeu_BaLyEn_6	78	83	PF01217	0.590
TRG_DiLeu_BaLyEn_6	890	895	PF01217	0.539
TRG_ENDOCYTIC_2	1007	1010	PF00928	0.411
TRG_ENDOCYTIC_2	401	404	PF00928	0.682
TRG_ENDOCYTIC_2	780	783	PF00928	0.623
TRG_ENDOCYTIC_2	920	923	PF00928	0.607
TRG_ENDOCYTIC_2	937	940	PF00928	0.465
TRG_ENDOCYTIC_2	995	998	PF00928	0.387
TRG_ER_diArg_1	225	228	PF00400	0.816
TRG_ER_diArg_1	300	303	PF00400	0.754
TRG_ER_diArg_1	382	384	PF00400	0.779
TRG_ER_diArg_1	474	476	PF00400	0.685
TRG_ER_diArg_1	673	675	PF00400	0.572
TRG_ER_diArg_1	731	733	PF00400	0.724
TRG_ER_diArg_1	799	801	PF00400	0.740
TRG_Pf-PMV_PEXEL_1	966	970	PF00026	0.411

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IA65	Leptomonas seymouri	44%	100%
A0A3S7X3A5	Leishmania donovani	99%	100%
A4HI89	Leishmania braziliensis	68%	97%
E9B0R6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	99%
Q4Q7G7	Leishmania major	90%	99%