Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Acetyltransferase (GNAT) family - putative

Species:

Leishmania infantum

UniProt:

A4I5F7_LEIIN

TriTrypDb:

LINF_300018200

Length:

351

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I5F7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I5F7

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	4
GO:0016407	acetyltransferase activity	5	3
GO:0016740	transferase activity	2	4
GO:0016746	acyltransferase activity	3	3
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	251	255	PF00656	0.470
CLV_NRD_NRD_1	184	186	PF00675	0.655
CLV_NRD_NRD_1	226	228	PF00675	0.304
CLV_NRD_NRD_1	252	254	PF00675	0.452
CLV_NRD_NRD_1	272	274	PF00675	0.524
CLV_NRD_NRD_1	304	306	PF00675	0.773
CLV_NRD_NRD_1	323	325	PF00675	0.347
CLV_NRD_NRD_1	330	332	PF00675	0.410
CLV_PCSK_KEX2_1	184	186	PF00082	0.655
CLV_PCSK_KEX2_1	225	227	PF00082	0.304
CLV_PCSK_KEX2_1	252	254	PF00082	0.452
CLV_PCSK_KEX2_1	272	274	PF00082	0.513
CLV_PCSK_KEX2_1	276	278	PF00082	0.566
CLV_PCSK_KEX2_1	304	306	PF00082	0.794
CLV_PCSK_KEX2_1	323	325	PF00082	0.401
CLV_PCSK_KEX2_1	330	332	PF00082	0.443
CLV_PCSK_PC1ET2_1	276	278	PF00082	0.584
CLV_PCSK_PC7_1	272	278	PF00082	0.618
CLV_PCSK_SKI1_1	273	277	PF00082	0.589
CLV_TASPASE1	65	71	PF01112	0.486
DEG_APCC_DBOX_1	261	269	PF00400	0.428
DEG_APCC_DBOX_1	81	89	PF00400	0.375
DEG_Nend_UBRbox_1	1	4	PF02207	0.591
DEG_SPOP_SBC_1	133	137	PF00917	0.470
DOC_ANK_TNKS_1	207	214	PF00023	0.294
DOC_ANK_TNKS_1	304	311	PF00023	0.510
DOC_CYCLIN_RxL_1	320	329	PF00134	0.377
DOC_CYCLIN_yCln2_LP_2	53	59	PF00134	0.519
DOC_MAPK_gen_1	79	88	PF00069	0.360
DOC_PP1_RVXF_1	321	328	PF00149	0.370
DOC_PP2B_LxvP_1	53	56	PF13499	0.523
DOC_USP7_MATH_1	10	14	PF00917	0.438
DOC_USP7_MATH_1	109	113	PF00917	0.570
DOC_USP7_MATH_1	202	206	PF00917	0.559
DOC_USP7_MATH_1	275	279	PF00917	0.574
DOC_USP7_MATH_1	39	43	PF00917	0.682
DOC_USP7_MATH_1	78	82	PF00917	0.427
DOC_USP7_MATH_1	94	98	PF00917	0.316
DOC_WW_Pin1_4	172	177	PF00397	0.669
DOC_WW_Pin1_4	183	188	PF00397	0.569
DOC_WW_Pin1_4	198	203	PF00397	0.483
LIG_14-3-3_CanoR_1	170	176	PF00244	0.660
LIG_14-3-3_CanoR_1	227	233	PF00244	0.304
LIG_14-3-3_CanoR_1	96	104	PF00244	0.508
LIG_deltaCOP1_diTrp_1	102	108	PF00928	0.530
LIG_deltaCOP1_diTrp_1	69	74	PF00928	0.433
LIG_FHA_1	176	182	PF00498	0.554
LIG_FHA_1	233	239	PF00498	0.489
LIG_FHA_1	9	15	PF00498	0.506
LIG_Integrin_RGD_1	279	281	PF01839	0.542
LIG_LIR_Gen_1	177	187	PF02991	0.541
LIG_LIR_Gen_1	212	222	PF02991	0.304
LIG_LIR_Gen_1	58	66	PF02991	0.453
LIG_LIR_Nem_3	177	182	PF02991	0.532
LIG_LIR_Nem_3	212	217	PF02991	0.338
LIG_LIR_Nem_3	58	62	PF02991	0.396
LIG_LIR_Nem_3	71	77	PF02991	0.425
LIG_Rb_LxCxE_1	235	254	PF01857	0.425
LIG_RPA_C_Fungi	248	260	PF08784	0.370
LIG_SH2_CRK	179	183	PF00017	0.541
LIG_SH2_CRK	322	326	PF00017	0.422
LIG_SH2_NCK_1	179	183	PF00017	0.541
LIG_SH2_PTP2	214	217	PF00017	0.369
LIG_SH2_SRC	59	62	PF00017	0.456
LIG_SH2_STAT5	21	24	PF00017	0.425
LIG_SH2_STAT5	214	217	PF00017	0.335
LIG_SH2_STAT5	332	335	PF00017	0.537
LIG_SH2_STAT5	59	62	PF00017	0.456
LIG_SH3_3	103	109	PF00018	0.615
LIG_SH3_3	216	222	PF00018	0.399
LIG_SUMO_SIM_anti_2	342	348	PF11976	0.350
LIG_SUMO_SIM_anti_2	58	64	PF11976	0.457
LIG_TRAF2_1	129	132	PF00917	0.602
LIG_TYR_ITIM	57	62	PF00017	0.396
MOD_CK1_1	121	127	PF00069	0.673
MOD_CK1_1	148	154	PF00069	0.556
MOD_CK1_1	172	178	PF00069	0.686
MOD_CK1_1	193	199	PF00069	0.630
MOD_CK1_1	42	48	PF00069	0.653
MOD_CK2_1	126	132	PF00069	0.681
MOD_CK2_1	303	309	PF00069	0.768
MOD_GlcNHglycan	122	126	PF01048	0.673
MOD_GlcNHglycan	128	131	PF01048	0.588
MOD_GlcNHglycan	147	150	PF01048	0.557
MOD_GlcNHglycan	153	156	PF01048	0.484
MOD_GlcNHglycan	171	174	PF01048	0.385
MOD_GlcNHglycan	192	195	PF01048	0.647
MOD_GlcNHglycan	41	44	PF01048	0.669
MOD_GlcNHglycan	97	100	PF01048	0.529
MOD_GSK3_1	100	107	PF00069	0.688
MOD_GSK3_1	109	116	PF00069	0.596
MOD_GSK3_1	198	205	PF00069	0.571
MOD_GSK3_1	228	235	PF00069	0.371
MOD_GSK3_1	264	271	PF00069	0.522
MOD_GSK3_1	39	46	PF00069	0.673
MOD_GSK3_1	6	13	PF00069	0.514
MOD_NEK2_1	268	273	PF00069	0.482
MOD_NEK2_2	16	21	PF00069	0.441
MOD_OFUCOSY	147	152	PF10250	0.570
MOD_PIKK_1	232	238	PF00454	0.323
MOD_PKA_2	169	175	PF00069	0.508
MOD_PKA_2	207	213	PF00069	0.347
MOD_PKA_2	303	309	PF00069	0.602
MOD_PKA_2	39	45	PF00069	0.557
MOD_PKA_2	78	84	PF00069	0.424
MOD_PKA_2	95	101	PF00069	0.379
MOD_Plk_1	281	287	PF00069	0.618
MOD_Plk_1	70	76	PF00069	0.438
MOD_Plk_4	177	183	PF00069	0.633
MOD_Plk_4	228	234	PF00069	0.346
MOD_Plk_4	55	61	PF00069	0.488
MOD_ProDKin_1	172	178	PF00069	0.679
MOD_ProDKin_1	183	189	PF00069	0.571
MOD_ProDKin_1	198	204	PF00069	0.480
TRG_ENDOCYTIC_2	179	182	PF00928	0.539
TRG_ENDOCYTIC_2	214	217	PF00928	0.350
TRG_ENDOCYTIC_2	322	325	PF00928	0.419
TRG_ENDOCYTIC_2	59	62	PF00928	0.391
TRG_ER_diArg_1	224	227	PF00400	0.304
TRG_ER_diArg_1	322	324	PF00400	0.375
TRG_ER_diArg_1	330	332	PF00400	0.412
TRG_NES_CRM1_1	52	65	PF08389	0.455
TRG_NLS_MonoExtC_3	275	281	PF00514	0.520
TRG_NLS_MonoExtN_4	273	280	PF00514	0.509
TRG_Pf-PMV_PEXEL_1	138	142	PF00026	0.575

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8W0	Leptomonas seymouri	45%	100%
A0A3S7X392	Leishmania donovani	99%	100%
A4HI78	Leishmania braziliensis	68%	100%
E9B0Q5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4Q7H8	Leishmania major	90%	100%