LeishMANIAdb
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Putative mitochondrial oligo_U binding protein TBRGG1

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative mitochondrial oligo_U binding protein TBRGG1
Gene product:
mitochondrial oligo U binding protein TBRGG1 - putative
Species:
Leishmania infantum
UniProt:
A4I5A9_LEIIN
TriTrypDb:
LINF_300013200
Length:
677

Annotations

Annotations by Jardim et al.

Mitochondrial protein, mitochondrial oligo_U binding TBRGG1

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005654 nucleoplasm 2 1
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4I5A9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I5A9

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0008152 metabolic process 1 1
GO:0009058 biosynthetic process 2 1
GO:0009059 macromolecule biosynthetic process 4 1
GO:0009987 cellular process 1 1
GO:0016070 RNA metabolic process 5 1
GO:0018130 heterocycle biosynthetic process 4 1
GO:0019438 aromatic compound biosynthetic process 4 1
GO:0032774 RNA biosynthetic process 5 1
GO:0034641 cellular nitrogen compound metabolic process 3 1
GO:0034654 nucleobase-containing compound biosynthetic process 4 1
GO:0043170 macromolecule metabolic process 3 1
GO:0044237 cellular metabolic process 2 1
GO:0044238 primary metabolic process 2 1
GO:0044249 cellular biosynthetic process 3 1
GO:0044271 cellular nitrogen compound biosynthetic process 4 1
GO:0046483 heterocycle metabolic process 3 1
GO:0071704 organic substance metabolic process 2 1
GO:0090304 nucleic acid metabolic process 4 1
GO:1901360 organic cyclic compound metabolic process 3 1
GO:1901362 organic cyclic compound biosynthetic process 4 1
GO:1901576 organic substance biosynthetic process 3 1
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 1
GO:0003723 RNA binding 4 1
GO:0005488 binding 1 1
GO:0097159 organic cyclic compound binding 2 1
GO:1901363 heterocyclic compound binding 2 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 101 103 PF00675 0.769
CLV_NRD_NRD_1 126 128 PF00675 0.714
CLV_NRD_NRD_1 152 154 PF00675 0.708
CLV_NRD_NRD_1 190 192 PF00675 0.507
CLV_NRD_NRD_1 194 196 PF00675 0.534
CLV_PCSK_KEX2_1 101 103 PF00082 0.769
CLV_PCSK_KEX2_1 126 128 PF00082 0.714
CLV_PCSK_KEX2_1 152 154 PF00082 0.716
CLV_PCSK_KEX2_1 190 192 PF00082 0.581
CLV_PCSK_KEX2_1 194 196 PF00082 0.525
CLV_PCSK_PC7_1 190 196 PF00082 0.454
CLV_PCSK_SKI1_1 174 178 PF00082 0.555
CLV_PCSK_SKI1_1 190 194 PF00082 0.510
CLV_PCSK_SKI1_1 4 8 PF00082 0.733
CLV_PCSK_SKI1_1 448 452 PF00082 0.523
CLV_PCSK_SKI1_1 522 526 PF00082 0.599
CLV_PCSK_SKI1_1 600 604 PF00082 0.424
DEG_APCC_DBOX_1 599 607 PF00400 0.428
DEG_Nend_Nbox_1 1 3 PF02207 0.803
DOC_CDC14_PxL_1 370 378 PF14671 0.394
DOC_MAPK_MEF2A_6 278 287 PF00069 0.501
DOC_PP1_RVXF_1 481 488 PF00149 0.386
DOC_PP4_FxxP_1 218 221 PF00568 0.552
DOC_PP4_FxxP_1 444 447 PF00568 0.406
DOC_SPAK_OSR1_1 182 186 PF12202 0.555
DOC_USP7_MATH_1 272 276 PF00917 0.466
DOC_USP7_MATH_1 313 317 PF00917 0.494
DOC_USP7_MATH_1 457 461 PF00917 0.539
DOC_USP7_MATH_1 512 516 PF00917 0.545
DOC_USP7_MATH_1 529 533 PF00917 0.479
DOC_USP7_MATH_1 659 663 PF00917 0.590
DOC_USP7_UBL2_3 170 174 PF12436 0.474
DOC_WW_Pin1_4 239 244 PF00397 0.440
DOC_WW_Pin1_4 254 259 PF00397 0.418
DOC_WW_Pin1_4 595 600 PF00397 0.532
DOC_WW_Pin1_4 644 649 PF00397 0.598
LIG_14-3-3_CanoR_1 133 138 PF00244 0.741
LIG_14-3-3_CanoR_1 147 151 PF00244 0.714
LIG_14-3-3_CanoR_1 16 22 PF00244 0.605
LIG_14-3-3_CanoR_1 389 396 PF00244 0.425
LIG_14-3-3_CanoR_1 4 9 PF00244 0.710
LIG_14-3-3_CanoR_1 413 419 PF00244 0.557
LIG_14-3-3_CanoR_1 492 498 PF00244 0.409
LIG_14-3-3_CanoR_1 519 529 PF00244 0.531
LIG_14-3-3_CanoR_1 564 568 PF00244 0.522
LIG_14-3-3_CanoR_1 600 609 PF00244 0.493
LIG_14-3-3_CanoR_1 619 627 PF00244 0.311
LIG_Actin_WH2_2 179 196 PF00022 0.466
LIG_Actin_WH2_2 579 594 PF00022 0.579
LIG_BRCT_BRCA1_1 553 557 PF00533 0.532
LIG_FHA_1 215 221 PF00498 0.470
LIG_FHA_1 389 395 PF00498 0.561
LIG_FHA_1 422 428 PF00498 0.539
LIG_FHA_1 497 503 PF00498 0.548
LIG_FHA_1 602 608 PF00498 0.453
LIG_FHA_2 194 200 PF00498 0.509
LIG_FHA_2 557 563 PF00498 0.503
LIG_FHA_2 583 589 PF00498 0.552
LIG_IRF3_LxIS_1 560 566 PF10401 0.435
LIG_LIR_Apic_2 217 221 PF02991 0.548
LIG_LIR_Apic_2 442 447 PF02991 0.407
LIG_LIR_Gen_1 228 238 PF02991 0.555
LIG_LIR_Nem_3 181 186 PF02991 0.463
LIG_LIR_Nem_3 481 485 PF02991 0.498
LIG_LIR_Nem_3 554 560 PF02991 0.434
LIG_PCNA_PIPBox_1 304 313 PF02747 0.557
LIG_PCNA_yPIPBox_3 262 270 PF02747 0.521
LIG_PCNA_yPIPBox_3 380 389 PF02747 0.503
LIG_SH2_CRK 18 22 PF00017 0.654
LIG_SH2_GRB2like 109 112 PF00017 0.835
LIG_SH2_GRB2like 81 84 PF00017 0.809
LIG_SH2_GRB2like 88 91 PF00017 0.832
LIG_SH2_NCK_1 456 460 PF00017 0.552
LIG_SH2_SRC 456 459 PF00017 0.550
LIG_SH2_SRC 88 91 PF00017 0.824
LIG_SH2_STAP1 18 22 PF00017 0.667
LIG_SH2_STAP1 553 557 PF00017 0.430
LIG_SH2_STAT3 158 161 PF00017 0.589
LIG_SH2_STAT3 57 60 PF00017 0.704
LIG_SH2_STAT5 158 161 PF00017 0.589
LIG_SH2_STAT5 95 98 PF00017 0.750
LIG_SH3_3 413 419 PF00018 0.554
LIG_SH3_3 459 465 PF00018 0.486
LIG_SH3_3 515 521 PF00018 0.543
LIG_SUMO_SIM_anti_2 207 212 PF11976 0.460
LIG_SUMO_SIM_anti_2 284 290 PF11976 0.393
LIG_SUMO_SIM_anti_2 365 371 PF11976 0.404
LIG_SUMO_SIM_anti_2 506 512 PF11976 0.486
LIG_TRAF2_1 426 429 PF00917 0.525
LIG_TRAF2_1 467 470 PF00917 0.548
LIG_UBA3_1 166 174 PF00899 0.445
LIG_UBA3_1 434 440 PF00899 0.512
LIG_UBA3_1 493 501 PF00899 0.536
LIG_WRC_WIRS_1 479 484 PF05994 0.570
LIG_WW_3 50 54 PF00397 0.743
LIG_WW_3 519 523 PF00397 0.520
MOD_CDK_SPK_2 595 600 PF00069 0.532
MOD_CK1_1 334 340 PF00069 0.605
MOD_CK1_1 417 423 PF00069 0.558
MOD_CK1_1 496 502 PF00069 0.539
MOD_CK1_1 644 650 PF00069 0.539
MOD_CK2_1 199 205 PF00069 0.461
MOD_CK2_1 254 260 PF00069 0.490
MOD_CK2_1 306 312 PF00069 0.513
MOD_CK2_1 457 463 PF00069 0.575
MOD_CK2_1 556 562 PF00069 0.462
MOD_CK2_1 582 588 PF00069 0.531
MOD_GlcNHglycan 148 151 PF01048 0.764
MOD_GlcNHglycan 406 409 PF01048 0.443
MOD_GlcNHglycan 441 444 PF01048 0.478
MOD_GlcNHglycan 448 451 PF01048 0.377
MOD_GlcNHglycan 465 468 PF01048 0.380
MOD_GlcNHglycan 503 506 PF01048 0.569
MOD_GlcNHglycan 522 525 PF01048 0.369
MOD_GlcNHglycan 663 666 PF01048 0.571
MOD_GSK3_1 321 328 PF00069 0.473
MOD_GSK3_1 417 424 PF00069 0.587
MOD_GSK3_1 468 475 PF00069 0.462
MOD_N-GLC_1 512 517 PF02516 0.546
MOD_N-GLC_1 619 624 PF02516 0.500
MOD_NEK2_1 193 198 PF00069 0.529
MOD_NEK2_1 376 381 PF00069 0.517
MOD_NEK2_1 472 477 PF00069 0.463
MOD_NEK2_1 493 498 PF00069 0.523
MOD_NEK2_1 582 587 PF00069 0.457
MOD_NEK2_1 654 659 PF00069 0.562
MOD_PIKK_1 117 123 PF00454 0.596
MOD_PIKK_1 157 163 PF00454 0.572
MOD_PIKK_1 199 205 PF00454 0.461
MOD_PIKK_1 376 382 PF00454 0.544
MOD_PIKK_1 496 502 PF00454 0.540
MOD_PKA_2 146 152 PF00069 0.728
MOD_PKA_2 193 199 PF00069 0.552
MOD_PKA_2 388 394 PF00069 0.486
MOD_PKA_2 563 569 PF00069 0.536
MOD_PKB_1 14 22 PF00069 0.640
MOD_PKB_1 72 80 PF00069 0.742
MOD_Plk_1 204 210 PF00069 0.427
MOD_Plk_1 512 518 PF00069 0.553
MOD_Plk_4 17 23 PF00069 0.627
MOD_Plk_4 272 278 PF00069 0.516
MOD_Plk_4 325 331 PF00069 0.473
MOD_Plk_4 472 478 PF00069 0.416
MOD_Plk_4 506 512 PF00069 0.416
MOD_ProDKin_1 239 245 PF00069 0.434
MOD_ProDKin_1 254 260 PF00069 0.423
MOD_ProDKin_1 595 601 PF00069 0.525
MOD_ProDKin_1 644 650 PF00069 0.588
MOD_SUMO_for_1 222 225 PF00179 0.575
MOD_SUMO_rev_2 257 264 PF00179 0.461
TRG_DiLeu_BaEn_1 188 193 PF01217 0.501
TRG_DiLeu_BaEn_1 365 370 PF01217 0.400
TRG_DiLeu_BaEn_4 298 304 PF01217 0.504
TRG_DiLeu_BaLyEn_6 162 167 PF01217 0.459
TRG_DiLeu_LyEn_5 188 193 PF01217 0.540
TRG_ENDOCYTIC_2 18 21 PF00928 0.650
TRG_ER_diArg_1 13 16 PF00400 0.734
TRG_ER_diArg_1 151 153 PF00400 0.768
TRG_ER_diArg_1 190 192 PF00400 0.488
TRG_ER_diArg_1 193 195 PF00400 0.487
TRG_NES_CRM1_1 279 293 PF08389 0.448
TRG_Pf-PMV_PEXEL_1 584 588 PF00026 0.582

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I169 Leptomonas seymouri 44% 100%
A0A0S4JB89 Bodo saltans 25% 91%
A0A1X0P251 Trypanosomatidae 38% 100%
A0A3S7X349 Leishmania donovani 100% 100%
A0A422P4U2 Trypanosoma rangeli 37% 100%
A4HI33 Leishmania braziliensis 80% 100%
C9ZQP3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 91%
E9B0K5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
Q4Q7M7 Leishmania major 92% 97%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS