Putative ubiquitin hydrolase

Quick info Annotations Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ubiquitin hydrolase - putative

Species:

Leishmania infantum

UniProt:

A4I519_LEIIN

TriTrypDb:

LINF_300007500

Length:

1132

Annotations

Annotations by Jardim et al.

Protein modification, ubiquitin hydrolase

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0000932	P-body	5	1
GO:0031251	PAN complex	2	1
GO:0032991	protein-containing complex	1	1
GO:0035770	ribonucleoprotein granule	3	1
GO:0036464	cytoplasmic ribonucleoprotein granule	4	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0099080	supramolecular complex	2	1
GO:0110165	cellular anatomical entity	1	1

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4I519

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I519

Function

Biological processes
Term	Name	Level	Count
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	8	1
GO:0000956	nuclear-transcribed mRNA catabolic process	7	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006401	RNA catabolic process	5	1
GO:0006402	mRNA catabolic process	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009056	catabolic process	2	1
GO:0009057	macromolecule catabolic process	4	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0009987	cellular process	1	1
GO:0010468	regulation of gene expression	5	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0010629	negative regulation of gene expression	6	1
GO:0016070	RNA metabolic process	5	1
GO:0016071	mRNA metabolic process	6	1
GO:0019222	regulation of metabolic process	3	1
GO:0019439	aromatic compound catabolic process	4	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034655	nucleobase-containing compound catabolic process	4	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044248	cellular catabolic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044265	obsolete cellular macromolecule catabolic process	4	1
GO:0044270	cellular nitrogen compound catabolic process	4	1
GO:0046483	heterocycle metabolic process	3	1
GO:0046700	heterocycle catabolic process	4	1
GO:0048519	negative regulation of biological process	3	1
GO:0050789	regulation of biological process	2	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1901361	organic cyclic compound catabolic process	4	1
GO:1901575	organic substance catabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	11
GO:0003824	catalytic activity	1	11
GO:0004518	nuclease activity	4	11
GO:0004527	exonuclease activity	5	11
GO:0005488	binding	1	11
GO:0016787	hydrolase activity	2	11
GO:0016788	hydrolase activity, acting on ester bonds	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:1901363	heterocyclic compound binding	2	11
GO:0000175	3'-5'-RNA exonuclease activity	7	1
GO:0004532	RNA exonuclease activity	5	1
GO:0004535	poly(A)-specific ribonuclease activity	8	1
GO:0004540	RNA nuclease activity	4	1
GO:0008408	3'-5' exonuclease activity	6	1
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	1
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	6	1
GO:0140098	catalytic activity, acting on RNA	3	1
GO:0140640	catalytic activity, acting on a nucleic acid	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	886	890	PF00656	0.531
CLV_NRD_NRD_1	1018	1020	PF00675	0.357
CLV_NRD_NRD_1	1126	1128	PF00675	0.658
CLV_NRD_NRD_1	228	230	PF00675	0.381
CLV_NRD_NRD_1	250	252	PF00675	0.365
CLV_NRD_NRD_1	441	443	PF00675	0.518
CLV_NRD_NRD_1	446	448	PF00675	0.504
CLV_NRD_NRD_1	517	519	PF00675	0.229
CLV_NRD_NRD_1	871	873	PF00675	0.582
CLV_NRD_NRD_1	967	969	PF00675	0.301
CLV_PCSK_KEX2_1	100	102	PF00082	0.366
CLV_PCSK_KEX2_1	250	252	PF00082	0.365
CLV_PCSK_KEX2_1	446	448	PF00082	0.487
CLV_PCSK_KEX2_1	527	529	PF00082	0.277
CLV_PCSK_KEX2_1	684	686	PF00082	0.381
CLV_PCSK_PC1ET2_1	100	102	PF00082	0.366
CLV_PCSK_PC1ET2_1	446	448	PF00082	0.487
CLV_PCSK_PC1ET2_1	527	529	PF00082	0.308
CLV_PCSK_PC1ET2_1	684	686	PF00082	0.381
CLV_PCSK_PC7_1	442	448	PF00082	0.592
CLV_PCSK_PC7_1	523	529	PF00082	0.308
CLV_PCSK_SKI1_1	1052	1056	PF00082	0.607
CLV_PCSK_SKI1_1	1074	1078	PF00082	0.725
CLV_PCSK_SKI1_1	141	145	PF00082	0.464
CLV_PCSK_SKI1_1	217	221	PF00082	0.395
CLV_PCSK_SKI1_1	262	266	PF00082	0.428
CLV_PCSK_SKI1_1	280	284	PF00082	0.507
CLV_PCSK_SKI1_1	443	447	PF00082	0.584
CLV_PCSK_SKI1_1	519	523	PF00082	0.242
CLV_PCSK_SKI1_1	601	605	PF00082	0.297
CLV_PCSK_SKI1_1	72	76	PF00082	0.440
CLV_PCSK_SKI1_1	819	823	PF00082	0.508
CLV_PCSK_SKI1_1	827	831	PF00082	0.509
CLV_PCSK_SKI1_1	86	90	PF00082	0.214
CLV_PCSK_SKI1_1	928	932	PF00082	0.228
DEG_APCC_DBOX_1	600	608	PF00400	0.508
DEG_SCF_FBW7_1	1059	1065	PF00400	0.697
DEG_SPOP_SBC_1	282	286	PF00917	0.471
DOC_ANK_TNKS_1	940	947	PF00023	0.508
DOC_CKS1_1	1059	1064	PF01111	0.671
DOC_CKS1_1	192	197	PF01111	0.479
DOC_CKS1_1	499	504	PF01111	0.508
DOC_CKS1_1	788	793	PF01111	0.464
DOC_CYCLIN_RxL_1	816	824	PF00134	0.493
DOC_CYCLIN_yClb5_NLxxxL_5	800	808	PF00134	0.482
DOC_CYCLIN_yCln2_LP_2	152	158	PF00134	0.462
DOC_CYCLIN_yCln2_LP_2	265	271	PF00134	0.433
DOC_CYCLIN_yCln2_LP_2	417	423	PF00134	0.541
DOC_MAPK_DCC_7	554	564	PF00069	0.508
DOC_MAPK_DCC_7	684	692	PF00069	0.359
DOC_MAPK_gen_1	197	205	PF00069	0.510
DOC_MAPK_gen_1	684	692	PF00069	0.324
DOC_MAPK_gen_1	872	878	PF00069	0.445
DOC_MAPK_HePTP_8	681	693	PF00069	0.462
DOC_MAPK_MEF2A_6	197	205	PF00069	0.510
DOC_MAPK_MEF2A_6	684	693	PF00069	0.325
DOC_PP1_RVXF_1	473	479	PF00149	0.508
DOC_PP2B_LxvP_1	152	155	PF13499	0.485
DOC_PP2B_LxvP_1	376	379	PF13499	0.555
DOC_PP2B_LxvP_1	701	704	PF13499	0.400
DOC_PP4_FxxP_1	331	334	PF00568	0.415
DOC_PP4_FxxP_1	583	586	PF00568	0.508
DOC_PP4_FxxP_1	830	833	PF00568	0.393
DOC_PP4_FxxP_1	978	981	PF00568	0.420
DOC_USP7_MATH_1	1011	1015	PF00917	0.428
DOC_USP7_MATH_1	1042	1046	PF00917	0.436
DOC_USP7_MATH_1	1117	1121	PF00917	0.679
DOC_USP7_MATH_1	17	21	PF00917	0.457
DOC_USP7_MATH_1	171	175	PF00917	0.439
DOC_USP7_MATH_1	193	197	PF00917	0.465
DOC_USP7_MATH_1	696	700	PF00917	0.549
DOC_USP7_MATH_1	772	776	PF00917	0.428
DOC_USP7_MATH_1	833	837	PF00917	0.373
DOC_USP7_MATH_1	879	883	PF00917	0.495
DOC_USP7_MATH_1	923	927	PF00917	0.428
DOC_USP7_UBL2_3	446	450	PF12436	0.534
DOC_WW_Pin1_4	1055	1060	PF00397	0.595
DOC_WW_Pin1_4	1066	1071	PF00397	0.569
DOC_WW_Pin1_4	191	196	PF00397	0.506
DOC_WW_Pin1_4	264	269	PF00397	0.395
DOC_WW_Pin1_4	283	288	PF00397	0.267
DOC_WW_Pin1_4	296	301	PF00397	0.302
DOC_WW_Pin1_4	457	462	PF00397	0.600
DOC_WW_Pin1_4	498	503	PF00397	0.498
DOC_WW_Pin1_4	6	11	PF00397	0.534
DOC_WW_Pin1_4	787	792	PF00397	0.438
DOC_WW_Pin1_4	798	803	PF00397	0.468
DOC_WW_Pin1_4	829	834	PF00397	0.374
LIG_14-3-3_CanoR_1	1012	1016	PF00244	0.428
LIG_14-3-3_CanoR_1	1127	1131	PF00244	0.630
LIG_14-3-3_CanoR_1	182	190	PF00244	0.474
LIG_14-3-3_CanoR_1	217	223	PF00244	0.386
LIG_14-3-3_CanoR_1	756	760	PF00244	0.390
LIG_14-3-3_CanoR_1	774	783	PF00244	0.357
LIG_14-3-3_CanoR_1	831	840	PF00244	0.484
LIG_14-3-3_CanoR_1	86	91	PF00244	0.461
LIG_14-3-3_CanoR_1	984	989	PF00244	0.428
LIG_BIR_II_1	1	5	PF00653	0.631
LIG_BIR_III_4	40	44	PF00653	0.444
LIG_BRCT_BRCA1_1	986	990	PF00533	0.428
LIG_Clathr_ClatBox_1	845	849	PF01394	0.299
LIG_deltaCOP1_diTrp_1	34	42	PF00928	0.314
LIG_DLG_GKlike_1	984	991	PF00625	0.428
LIG_EH1_1	958	966	PF00400	0.531
LIG_FHA_1	1049	1055	PF00498	0.634
LIG_FHA_1	1059	1065	PF00498	0.697
LIG_FHA_1	138	144	PF00498	0.396
LIG_FHA_1	147	153	PF00498	0.402
LIG_FHA_1	218	224	PF00498	0.354
LIG_FHA_1	499	505	PF00498	0.428
LIG_FHA_1	531	537	PF00498	0.466
LIG_FHA_1	799	805	PF00498	0.496
LIG_FHA_1	811	817	PF00498	0.353
LIG_FHA_1	972	978	PF00498	0.458
LIG_FHA_2	1101	1107	PF00498	0.756
LIG_FHA_2	1116	1122	PF00498	0.571
LIG_FHA_2	23	29	PF00498	0.436
LIG_FHA_2	235	241	PF00498	0.507
LIG_FHA_2	320	326	PF00498	0.423
LIG_FHA_2	87	93	PF00498	0.369
LIG_FHA_2	892	898	PF00498	0.435
LIG_IBAR_NPY_1	419	421	PF08397	0.615
LIG_Integrin_isoDGR_2	643	645	PF01839	0.559
LIG_Integrin_RGD_1	14	16	PF01839	0.501
LIG_IRF3_LxIS_1	703	710	PF10401	0.436
LIG_LIR_Apic_2	1043	1049	PF02991	0.403
LIG_LIR_Apic_2	329	334	PF02991	0.414
LIG_LIR_Apic_2	345	349	PF02991	0.514
LIG_LIR_Apic_2	497	502	PF02991	0.508
LIG_LIR_Apic_2	580	586	PF02991	0.458
LIG_LIR_Apic_2	976	981	PF02991	0.480
LIG_LIR_Gen_1	220	228	PF02991	0.449
LIG_LIR_Gen_1	370	379	PF02991	0.588
LIG_LIR_Gen_1	480	489	PF02991	0.376
LIG_LIR_Gen_1	715	725	PF02991	0.427
LIG_LIR_Gen_1	746	757	PF02991	0.355
LIG_LIR_Gen_1	775	784	PF02991	0.436
LIG_LIR_Gen_1	790	798	PF02991	0.537
LIG_LIR_Gen_1	835	845	PF02991	0.463
LIG_LIR_Gen_1	849	858	PF02991	0.337
LIG_LIR_Gen_1	897	906	PF02991	0.508
LIG_LIR_Gen_1	935	944	PF02991	0.430
LIG_LIR_Gen_1	983	993	PF02991	0.500
LIG_LIR_Nem_3	1027	1033	PF02991	0.385
LIG_LIR_Nem_3	220	225	PF02991	0.452
LIG_LIR_Nem_3	313	317	PF02991	0.452
LIG_LIR_Nem_3	370	376	PF02991	0.592
LIG_LIR_Nem_3	40	45	PF02991	0.330
LIG_LIR_Nem_3	477	481	PF02991	0.422
LIG_LIR_Nem_3	715	720	PF02991	0.453
LIG_LIR_Nem_3	746	752	PF02991	0.360
LIG_LIR_Nem_3	775	779	PF02991	0.427
LIG_LIR_Nem_3	781	785	PF02991	0.368
LIG_LIR_Nem_3	790	796	PF02991	0.422
LIG_LIR_Nem_3	835	840	PF02991	0.390
LIG_LIR_Nem_3	849	855	PF02991	0.223
LIG_LIR_Nem_3	897	902	PF02991	0.475
LIG_LIR_Nem_3	911	916	PF02991	0.366
LIG_LIR_Nem_3	935	940	PF02991	0.430
LIG_LIR_Nem_3	983	988	PF02991	0.435
LIG_LYPXL_yS_3	617	620	PF13949	0.428
LIG_NRBOX	666	672	PF00104	0.394
LIG_NRBOX	803	809	PF00104	0.468
LIG_Pex14_2	222	226	PF04695	0.448
LIG_Pex14_2	495	499	PF04695	0.428
LIG_Pex14_2	636	640	PF04695	0.428
LIG_SH2_CRK	1021	1025	PF00017	0.385
LIG_SH2_CRK	373	377	PF00017	0.523
LIG_SH2_CRK	717	721	PF00017	0.451
LIG_SH2_CRK	776	780	PF00017	0.436
LIG_SH2_CRK	913	917	PF00017	0.428
LIG_SH2_CRK	993	997	PF00017	0.428
LIG_SH2_NCK_1	481	485	PF00017	0.395
LIG_SH2_NCK_1	622	626	PF00017	0.508
LIG_SH2_PTP2	118	121	PF00017	0.381
LIG_SH2_PTP2	852	855	PF00017	0.320
LIG_SH2_PTP2	899	902	PF00017	0.508
LIG_SH2_SRC	252	255	PF00017	0.542
LIG_SH2_SRC	899	902	PF00017	0.508
LIG_SH2_STAP1	776	780	PF00017	0.436
LIG_SH2_STAT3	470	473	PF00017	0.492
LIG_SH2_STAT3	508	511	PF00017	0.508
LIG_SH2_STAT3	677	680	PF00017	0.509
LIG_SH2_STAT3	868	871	PF00017	0.643
LIG_SH2_STAT3	909	912	PF00017	0.428
LIG_SH2_STAT5	1047	1050	PF00017	0.430
LIG_SH2_STAT5	118	121	PF00017	0.384
LIG_SH2_STAT5	133	136	PF00017	0.363
LIG_SH2_STAT5	180	183	PF00017	0.394
LIG_SH2_STAT5	326	329	PF00017	0.422
LIG_SH2_STAT5	508	511	PF00017	0.428
LIG_SH2_STAT5	719	722	PF00017	0.323
LIG_SH2_STAT5	837	840	PF00017	0.423
LIG_SH2_STAT5	852	855	PF00017	0.196
LIG_SH2_STAT5	868	871	PF00017	0.515
LIG_SH2_STAT5	899	902	PF00017	0.428
LIG_SH2_STAT5	909	912	PF00017	0.428
LIG_SH2_STAT5	937	940	PF00017	0.428
LIG_SH2_STAT5	985	988	PF00017	0.424
LIG_SH3_1	1056	1062	PF00018	0.700
LIG_SH3_2	513	518	PF14604	0.442
LIG_SH3_3	1056	1062	PF00018	0.631
LIG_SH3_3	331	337	PF00018	0.430
LIG_SH3_3	510	516	PF00018	0.442
LIG_SH3_3	557	563	PF00018	0.531
LIG_SH3_3	754	760	PF00018	0.370
LIG_SH3_3	897	903	PF00018	0.425
LIG_SH3_5	369	373	PF00018	0.613
LIG_SUMO_SIM_anti_2	185	191	PF11976	0.524
LIG_SUMO_SIM_anti_2	32	37	PF11976	0.312
LIG_SUMO_SIM_par_1	844	849	PF11976	0.304
LIG_SUMO_SIM_par_1	85	92	PF11976	0.382
LIG_TRAF2_1	345	348	PF00917	0.583
LIG_TRAF2_1	999	1002	PF00917	0.508
LIG_TRFH_1	264	268	PF08558	0.395
LIG_TYR_ITIM	991	996	PF00017	0.428
LIG_TYR_ITSM	909	916	PF00017	0.428
LIG_UBA3_1	273	280	PF00899	0.487
LIG_UBA3_1	438	446	PF00899	0.517
LIG_UBA3_1	521	527	PF00899	0.508
LIG_UBA3_1	670	678	PF00899	0.538
LIG_UBA3_1	971	980	PF00899	0.442
LIG_Vh1_VBS_1	656	674	PF01044	0.396
LIG_WRC_WIRS_1	1087	1092	PF05994	0.726
LIG_WRC_WIRS_1	328	333	PF05994	0.524
LIG_WRC_WIRS_1	45	50	PF05994	0.321
LIG_WRC_WIRS_1	64	69	PF05994	0.360
LIG_WRC_WIRS_1	779	784	PF05994	0.378
LIG_WW_1	625	628	PF00397	0.508
MOD_CDK_SPxK_1	191	197	PF00069	0.515
MOD_CDK_SPxK_1	6	12	PF00069	0.526
MOD_CK1_1	1026	1032	PF00069	0.385
MOD_CK1_1	185	191	PF00069	0.508
MOD_CK1_1	2	8	PF00069	0.647
MOD_CK1_1	215	221	PF00069	0.426
MOD_CK1_1	286	292	PF00069	0.579
MOD_CK1_1	49	55	PF00069	0.424
MOD_CK1_1	65	71	PF00069	0.405
MOD_CK1_1	832	838	PF00069	0.467
MOD_CK1_1	926	932	PF00069	0.508
MOD_CK2_1	1115	1121	PF00069	0.617
MOD_CK2_1	22	28	PF00069	0.443
MOD_CK2_1	342	348	PF00069	0.606
MOD_CK2_1	457	463	PF00069	0.566
MOD_CK2_1	477	483	PF00069	0.193
MOD_CK2_1	491	497	PF00069	0.370
MOD_CK2_1	833	839	PF00069	0.420
MOD_CK2_1	856	862	PF00069	0.542
MOD_CK2_1	996	1002	PF00069	0.508
MOD_GlcNHglycan	173	176	PF01048	0.357
MOD_GlcNHglycan	182	185	PF01048	0.337
MOD_GlcNHglycan	216	220	PF01048	0.496
MOD_GlcNHglycan	242	245	PF01048	0.507
MOD_GlcNHglycan	546	549	PF01048	0.259
MOD_GlcNHglycan	658	661	PF01048	0.471
MOD_GlcNHglycan	776	779	PF01048	0.442
MOD_GlcNHglycan	913	916	PF01048	0.228
MOD_GSK3_1	1	8	PF00069	0.685
MOD_GSK3_1	1058	1065	PF00069	0.618
MOD_GSK3_1	146	153	PF00069	0.520
MOD_GSK3_1	169	176	PF00069	0.342
MOD_GSK3_1	240	247	PF00069	0.375
MOD_GSK3_1	282	289	PF00069	0.480
MOD_GSK3_1	542	549	PF00069	0.494
MOD_GSK3_1	63	70	PF00069	0.440
MOD_GSK3_1	635	642	PF00069	0.430
MOD_GSK3_1	703	710	PF00069	0.489
MOD_GSK3_1	774	781	PF00069	0.405
MOD_GSK3_1	829	836	PF00069	0.384
MOD_GSK3_1	879	886	PF00069	0.432
MOD_GSK3_1	924	931	PF00069	0.428
MOD_GSK3_1	980	987	PF00069	0.508
MOD_N-GLC_1	244	249	PF02516	0.497
MOD_N-GLC_1	62	67	PF02516	0.484
MOD_N-GLC_1	786	791	PF02516	0.491
MOD_N-GLC_2	302	304	PF02516	0.471
MOD_NEK2_1	1	6	PF00069	0.699
MOD_NEK2_1	131	136	PF00069	0.424
MOD_NEK2_1	156	161	PF00069	0.399
MOD_NEK2_1	206	211	PF00069	0.427
MOD_NEK2_1	374	379	PF00069	0.665
MOD_NEK2_1	46	51	PF00069	0.335
MOD_NEK2_1	462	467	PF00069	0.548
MOD_NEK2_1	503	508	PF00069	0.455
MOD_NEK2_1	543	548	PF00069	0.430
MOD_NEK2_1	567	572	PF00069	0.407
MOD_NEK2_1	67	72	PF00069	0.373
MOD_NEK2_1	707	712	PF00069	0.516
MOD_NEK2_1	796	801	PF00069	0.516
MOD_NEK2_1	867	872	PF00069	0.598
MOD_NEK2_1	924	929	PF00069	0.428
MOD_NEK2_1	933	938	PF00069	0.428
MOD_NEK2_1	996	1001	PF00069	0.508
MOD_NEK2_2	1011	1016	PF00069	0.428
MOD_NEK2_2	778	783	PF00069	0.380
MOD_PIKK_1	2	8	PF00454	0.648
MOD_PIKK_1	244	250	PF00454	0.382
MOD_PIKK_1	422	428	PF00454	0.681
MOD_PIKK_1	49	55	PF00454	0.422
MOD_PIKK_1	737	743	PF00454	0.465
MOD_PIKK_1	867	873	PF00454	0.550
MOD_PIKK_1	908	914	PF00454	0.428
MOD_PK_1	412	418	PF00069	0.665
MOD_PKA_2	1011	1017	PF00069	0.428
MOD_PKA_2	1126	1132	PF00069	0.636
MOD_PKA_2	755	761	PF00069	0.387
MOD_PKA_2	879	885	PF00069	0.428
MOD_Plk_1	1042	1048	PF00069	0.399
MOD_Plk_1	156	162	PF00069	0.467
MOD_Plk_1	185	191	PF00069	0.524
MOD_Plk_1	206	212	PF00069	0.339
MOD_Plk_1	244	250	PF00069	0.494
MOD_Plk_1	355	361	PF00069	0.478
MOD_Plk_1	462	468	PF00069	0.543
MOD_Plk_1	491	497	PF00069	0.428
MOD_Plk_1	62	68	PF00069	0.487
MOD_Plk_1	745	751	PF00069	0.481
MOD_Plk_1	891	897	PF00069	0.442
MOD_Plk_2-3	1004	1010	PF00069	0.428
MOD_Plk_2-3	1086	1092	PF00069	0.648
MOD_Plk_2-3	477	483	PF00069	0.452
MOD_Plk_2-3	891	897	PF00069	0.442
MOD_Plk_4	1042	1048	PF00069	0.439
MOD_Plk_4	1050	1056	PF00069	0.543
MOD_Plk_4	1062	1068	PF00069	0.392
MOD_Plk_4	156	162	PF00069	0.492
MOD_Plk_4	185	191	PF00069	0.452
MOD_Plk_4	206	212	PF00069	0.339
MOD_Plk_4	218	224	PF00069	0.366
MOD_Plk_4	310	316	PF00069	0.465
MOD_Plk_4	327	333	PF00069	0.522
MOD_Plk_4	388	394	PF00069	0.572
MOD_Plk_4	41	47	PF00069	0.437
MOD_Plk_4	412	418	PF00069	0.585
MOD_Plk_4	503	509	PF00069	0.430
MOD_Plk_4	546	552	PF00069	0.498
MOD_Plk_4	778	784	PF00069	0.380
MOD_Plk_4	933	939	PF00069	0.428
MOD_ProDKin_1	1055	1061	PF00069	0.595
MOD_ProDKin_1	1066	1072	PF00069	0.571
MOD_ProDKin_1	191	197	PF00069	0.515
MOD_ProDKin_1	264	270	PF00069	0.394
MOD_ProDKin_1	283	289	PF00069	0.277
MOD_ProDKin_1	296	302	PF00069	0.304
MOD_ProDKin_1	457	463	PF00069	0.596
MOD_ProDKin_1	498	504	PF00069	0.498
MOD_ProDKin_1	6	12	PF00069	0.526
MOD_ProDKin_1	787	793	PF00069	0.439
MOD_ProDKin_1	798	804	PF00069	0.459
MOD_ProDKin_1	829	835	PF00069	0.379
MOD_SUMO_for_1	1024	1027	PF00179	0.449
MOD_SUMO_for_1	553	556	PF00179	0.508
MOD_SUMO_rev_2	1045	1054	PF00179	0.576
MOD_SUMO_rev_2	610	616	PF00179	0.463
TRG_DiLeu_BaEn_1	765	770	PF01217	0.479
TRG_DiLeu_BaEn_3	370	376	PF01217	0.630
TRG_DiLeu_BaLyEn_6	138	143	PF01217	0.478
TRG_DiLeu_BaLyEn_6	499	504	PF01217	0.508
TRG_DiLeu_BaLyEn_6	807	812	PF01217	0.325
TRG_DiLeu_BaLyEn_6	817	822	PF01217	0.375
TRG_ENDOCYTIC_2	1021	1024	PF00928	0.359
TRG_ENDOCYTIC_2	118	121	PF00928	0.371
TRG_ENDOCYTIC_2	373	376	PF00928	0.527
TRG_ENDOCYTIC_2	459	462	PF00928	0.497
TRG_ENDOCYTIC_2	481	484	PF00928	0.402
TRG_ENDOCYTIC_2	617	620	PF00928	0.428
TRG_ENDOCYTIC_2	64	67	PF00928	0.362
TRG_ENDOCYTIC_2	653	656	PF00928	0.370
TRG_ENDOCYTIC_2	717	720	PF00928	0.457
TRG_ENDOCYTIC_2	776	779	PF00928	0.370
TRG_ENDOCYTIC_2	793	796	PF00928	0.252
TRG_ENDOCYTIC_2	837	840	PF00928	0.430
TRG_ENDOCYTIC_2	852	855	PF00928	0.208
TRG_ENDOCYTIC_2	899	902	PF00928	0.475
TRG_ENDOCYTIC_2	913	916	PF00928	0.366
TRG_ENDOCYTIC_2	937	940	PF00928	0.428
TRG_ENDOCYTIC_2	985	988	PF00928	0.428
TRG_ENDOCYTIC_2	993	996	PF00928	0.428
TRG_ER_diArg_1	197	200	PF00400	0.393
TRG_ER_diArg_1	249	251	PF00400	0.364
TRG_NLS_MonoExtC_3	445	450	PF00514	0.541
TRG_NLS_MonoExtN_4	443	450	PF00514	0.510
TRG_Pf-PMV_PEXEL_1	569	573	PF00026	0.276
TRG_Pf-PMV_PEXEL_1	819	824	PF00026	0.484
TRG_Pf-PMV_PEXEL_1	893	897	PF00026	0.224
TRG_Pf-PMV_PEXEL_1	941	945	PF00026	0.228

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8P8	Leptomonas seymouri	89%	100%
A0A1X0P284	Trypanosomatidae	60%	100%
A0A3Q8IJ46	Leishmania donovani	100%	100%
A0A3R7M0B3	Trypanosoma rangeli	61%	100%
A4HHW9	Leishmania braziliensis	94%	100%
C9ZQH8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	100%
E9B0E9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
Q4Q7T4	Leishmania major	98%	100%
V5BCC5	Trypanosoma cruzi	62%	100%