Putative mitotic cyclin

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

mitotic cyclin - putative

Species:

Leishmania infantum

UniProt:

A4I503_LEIIN

TriTrypDb:

LINF_300005800

Length:

420

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Show entries

Cellular components
Term	Name	Level	Count
GO:0000307	cyclin-dependent protein kinase holoenzyme complex	7	1
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0032991	protein-containing complex	1	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0061695	transferase complex, transferring phosphorus-containing groups	4	1
GO:0110165	cellular anatomical entity	1	1

Previous1 2Next

Expansion

Sequence features

A4I503

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I503

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	6	1
GO:0001932	regulation of protein phosphorylation	7	1
GO:0009987	cellular process	1	1
GO:0019220	regulation of phosphate metabolic process	6	1
GO:0019222	regulation of metabolic process	3	1
GO:0022402	cell cycle process	2	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031399	regulation of protein modification process	6	1
GO:0042325	regulation of phosphorylation	7	1
GO:0043549	regulation of kinase activity	5	1

Previous1 2 3Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	5	1
GO:0019207	kinase regulator activity	3	1
GO:0019887	protein kinase regulator activity	4	1
GO:0030234	enzyme regulator activity	2	1
GO:0098772	molecular function regulator activity	1	1

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	131	135	PF00656	0.317
CLV_NRD_NRD_1	140	142	PF00675	0.536
CLV_NRD_NRD_1	283	285	PF00675	0.603
CLV_NRD_NRD_1	359	361	PF00675	0.378
CLV_NRD_NRD_1	417	419	PF00675	0.481
CLV_NRD_NRD_1	72	74	PF00675	0.518
CLV_PCSK_KEX2_1	283	285	PF00082	0.598
CLV_PCSK_KEX2_1	359	361	PF00082	0.415
CLV_PCSK_KEX2_1	417	419	PF00082	0.481
CLV_PCSK_KEX2_1	72	74	PF00082	0.582

Previous1 2 3 4 5…16Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8P2	Leptomonas seymouri	80%	100%
A0A0S4JZZ8	Bodo saltans	46%	99%
A0A1X0P2F8	Trypanosomatidae	46%	100%
A0A3Q8IHJ8	Leishmania donovani	99%	100%
A4HHV3	Leishmania braziliensis	91%	100%
C9ZQF2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	93%
E9B0D3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
Q4Q7U8	Leishmania major	96%	100%

Previous1Next