Intraflagellar transport protein 56

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Putative intraflagellar transport protein C3

Species:

Leishmania infantum

UniProt:

A4I4Z3_LEIIN

TriTrypDb:

LINF_290035400

Length:

568

Annotations

Annotations by Jardim et al.

Flagella, intraflagellar transport C3 (PIFTC3) Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	yes	yes: 6
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 7

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 14

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Show entries

Cellular components
Term	Name	Level	Count
GO:0005815	microtubule organizing center	2	1
GO:0005929	cilium	4	1
GO:0030990	intraciliary transport particle	2	1
GO:0030992	intraciliary transport particle B	2	1
GO:0031514	motile cilium	5	1
GO:0032991	protein-containing complex	1	1
GO:0036064	ciliary basal body	3	1
GO:0042995	cell projection	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1

Previous1 2Next

Expansion

Sequence features

A4I4Z3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I4Z3

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	1
GO:0007017	microtubule-based process	2	1
GO:0007018	microtubule-based movement	3	1
GO:0009987	cellular process	1	1
GO:0010970	transport along microtubule	4	1
GO:0030705	cytoskeleton-dependent intracellular transport	4	1
GO:0031503	protein-containing complex localization	2	1
GO:0035720	intraciliary anterograde transport	4	1
GO:0035735	intraciliary transport involved in cilium assembly	4	1
GO:0042073	intraciliary transport	3	1

Previous1 2Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	1
GO:0044877	protein-containing complex binding	2	1
GO:0120170	intraciliary transport particle B binding	3	1

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	492	496	PF00656	0.385
CLV_NRD_NRD_1	18	20	PF00675	0.610
CLV_NRD_NRD_1	9	11	PF00675	0.609
CLV_PCSK_KEX2_1	566	568	PF00082	0.531
CLV_PCSK_PC1ET2_1	566	568	PF00082	0.551
CLV_PCSK_SKI1_1	129	133	PF00082	0.336
CLV_PCSK_SKI1_1	179	183	PF00082	0.361
CLV_PCSK_SKI1_1	240	244	PF00082	0.481
CLV_PCSK_SKI1_1	348	352	PF00082	0.477
CLV_PCSK_SKI1_1	388	392	PF00082	0.348

Previous1 2 3 4 5…20Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6K7	Leptomonas seymouri	83%	100%
A0A0S4KM55	Bodo saltans	64%	100%
A0A1X0PAC6	Trypanosomatidae	68%	100%
A0A3Q8IEI7	Leishmania donovani	100%	100%
A0A3R7NBU5	Trypanosoma rangeli	68%	100%
A0AVF1	Homo sapiens	49%	100%
A4HHT3	Leishmania braziliensis	93%	100%
A4III8	Xenopus tropicalis	51%	100%
A8JA42	Chlamydomonas reinhardtii	48%	100%
C9ZKK5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	68%	100%

Previous1 2Next