Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

START domain containing protein - putative

Species:

Leishmania infantum

UniProt:

A4I4Z0_LEIIN

TriTrypDb:

LINF_290035100

Length:

366

Annotations

Annotations by Jardim et al.

Lipid Metabolism, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	yes	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 12

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 14

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 18
NetGPI	no	yes: 0, no: 18

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I4Z0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I4Z0

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	19
GO:0008289	lipid binding	2	19

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	24	26	PF00675	0.441
CLV_NRD_NRD_1	360	362	PF00675	0.474
CLV_PCSK_KEX2_1	360	362	PF00082	0.415
CLV_PCSK_SKI1_1	15	19	PF00082	0.376
CLV_PCSK_SKI1_1	162	166	PF00082	0.291
CLV_PCSK_SKI1_1	207	211	PF00082	0.414
CLV_PCSK_SKI1_1	334	338	PF00082	0.467
CLV_PCSK_SKI1_1	68	72	PF00082	0.365
DEG_APCC_DBOX_1	14	22	PF00400	0.407
DEG_Nend_UBRbox_2	1	3	PF02207	0.619

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6J9	Leptomonas seymouri	74%	99%
A0A0S4KH88	Bodo saltans	48%	93%
A0A1X0P910	Trypanosomatidae	51%	97%
A0A3Q8IBA5	Leishmania donovani	34%	100%
A0A3Q8IJ21	Leishmania donovani	100%	100%
A0A3R7KCX0	Trypanosoma rangeli	48%	100%
A4H6L4	Leishmania braziliensis	35%	100%
A4HHT0	Leishmania braziliensis	82%	100%
A4HUZ7	Leishmania infantum	34%	89%
C9ZKK9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	99%

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