Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I4V6_LEIIN

TriTrypDb:

LINF_290031900

Length:

842

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I4V6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	166	170	PF00656	0.479
CLV_C14_Caspase3-7	379	383	PF00656	0.527
CLV_C14_Caspase3-7	546	550	PF00656	0.504
CLV_NRD_NRD_1	143	145	PF00675	0.483
CLV_NRD_NRD_1	265	267	PF00675	0.599
CLV_NRD_NRD_1	338	340	PF00675	0.523
CLV_NRD_NRD_1	374	376	PF00675	0.474
CLV_NRD_NRD_1	397	399	PF00675	0.477
CLV_NRD_NRD_1	427	429	PF00675	0.645
CLV_NRD_NRD_1	446	448	PF00675	0.263
CLV_NRD_NRD_1	607	609	PF00675	0.473
CLV_NRD_NRD_1	610	612	PF00675	0.508
CLV_NRD_NRD_1	615	617	PF00675	0.544
CLV_NRD_NRD_1	658	660	PF00675	0.585
CLV_NRD_NRD_1	7	9	PF00675	0.255
CLV_NRD_NRD_1	781	783	PF00675	0.515
CLV_PCSK_FUR_1	336	340	PF00082	0.590
CLV_PCSK_FUR_1	425	429	PF00082	0.486
CLV_PCSK_FUR_1	5	9	PF00082	0.260
CLV_PCSK_FUR_1	608	612	PF00082	0.492
CLV_PCSK_KEX2_1	143	145	PF00082	0.362
CLV_PCSK_KEX2_1	265	267	PF00082	0.637
CLV_PCSK_KEX2_1	338	340	PF00082	0.504
CLV_PCSK_KEX2_1	396	398	PF00082	0.435
CLV_PCSK_KEX2_1	427	429	PF00082	0.621
CLV_PCSK_KEX2_1	446	448	PF00082	0.264
CLV_PCSK_KEX2_1	606	608	PF00082	0.472
CLV_PCSK_KEX2_1	610	612	PF00082	0.504
CLV_PCSK_KEX2_1	658	660	PF00082	0.630
CLV_PCSK_KEX2_1	7	9	PF00082	0.255
CLV_PCSK_KEX2_1	781	783	PF00082	0.593
CLV_PCSK_PC7_1	3	9	PF00082	0.267
CLV_PCSK_PC7_1	606	612	PF00082	0.484
CLV_PCSK_SKI1_1	143	147	PF00082	0.459
CLV_PCSK_SKI1_1	367	371	PF00082	0.531
CLV_PCSK_SKI1_1	68	72	PF00082	0.284
DEG_APCC_DBOX_1	377	385	PF00400	0.495
DEG_COP1_1	356	364	PF00400	0.533
DEG_COP1_1	379	389	PF00400	0.503
DEG_COP1_1	410	419	PF00400	0.436
DEG_SCF_FBW7_1	582	589	PF00400	0.698
DEG_SPOP_SBC_1	635	639	PF00917	0.505
DEG_SPOP_SBC_1	700	704	PF00917	0.566
DEG_SPOP_SBC_1	754	758	PF00917	0.650
DEG_SPOP_SBC_1	773	777	PF00917	0.645
DOC_CKS1_1	464	469	PF01111	0.538
DOC_CKS1_1	570	575	PF01111	0.540
DOC_CKS1_1	583	588	PF01111	0.426
DOC_CYCLIN_RxL_1	140	148	PF00134	0.319
DOC_CYCLIN_yCln2_LP_2	154	160	PF00134	0.389
DOC_CYCLIN_yCln2_LP_2	464	470	PF00134	0.527
DOC_MAPK_DCC_7	248	258	PF00069	0.511
DOC_MAPK_gen_1	241	251	PF00069	0.651
DOC_MAPK_gen_1	296	306	PF00069	0.511
DOC_MAPK_MEF2A_6	244	251	PF00069	0.603
DOC_PP1_RVXF_1	448	455	PF00149	0.512
DOC_PP2B_LxvP_1	154	157	PF13499	0.355
DOC_PP4_FxxP_1	55	58	PF00568	0.202
DOC_USP7_MATH_1	139	143	PF00917	0.446
DOC_USP7_MATH_1	203	207	PF00917	0.523
DOC_USP7_MATH_1	320	324	PF00917	0.556
DOC_USP7_MATH_1	415	419	PF00917	0.608
DOC_USP7_MATH_1	502	506	PF00917	0.599
DOC_USP7_MATH_1	51	55	PF00917	0.301
DOC_USP7_MATH_1	534	538	PF00917	0.510
DOC_USP7_MATH_1	555	559	PF00917	0.671
DOC_USP7_MATH_1	560	564	PF00917	0.630
DOC_USP7_MATH_1	592	596	PF00917	0.522
DOC_USP7_MATH_1	635	639	PF00917	0.529
DOC_USP7_MATH_1	643	647	PF00917	0.502
DOC_USP7_MATH_1	657	661	PF00917	0.609
DOC_USP7_MATH_1	699	703	PF00917	0.588
DOC_USP7_MATH_1	754	758	PF00917	0.575
DOC_USP7_MATH_1	785	789	PF00917	0.533
DOC_USP7_MATH_1	832	836	PF00917	0.564
DOC_USP7_UBL2_3	322	326	PF12436	0.627
DOC_WW_Pin1_4	195	200	PF00397	0.672
DOC_WW_Pin1_4	249	254	PF00397	0.581
DOC_WW_Pin1_4	456	461	PF00397	0.428
DOC_WW_Pin1_4	463	468	PF00397	0.439
DOC_WW_Pin1_4	551	556	PF00397	0.619
DOC_WW_Pin1_4	569	574	PF00397	0.535
DOC_WW_Pin1_4	582	587	PF00397	0.644
DOC_WW_Pin1_4	701	706	PF00397	0.551
DOC_WW_Pin1_4	713	718	PF00397	0.412
DOC_WW_Pin1_4	781	786	PF00397	0.531
LIG_14-3-3_CanoR_1	109	115	PF00244	0.437
LIG_14-3-3_CanoR_1	191	199	PF00244	0.567
LIG_14-3-3_CanoR_1	25	35	PF00244	0.194
LIG_14-3-3_CanoR_1	5	11	PF00244	0.251
LIG_14-3-3_CanoR_1	743	749	PF00244	0.594
LIG_14-3-3_CanoR_1	753	763	PF00244	0.620
LIG_14-3-3_CanoR_1	772	779	PF00244	0.625
LIG_14-3-3_CanoR_1	83	87	PF00244	0.353
LIG_14-3-3_CterR_2	838	842	PF00244	0.482
LIG_BIR_III_4	549	553	PF00653	0.539
LIG_BRCT_BRCA1_1	51	55	PF00533	0.357
LIG_BRCT_BRCA1_1	61	65	PF00533	0.175
LIG_deltaCOP1_diTrp_1	451	461	PF00928	0.546
LIG_deltaCOP1_diTrp_1	814	820	PF00928	0.395
LIG_FHA_1	208	214	PF00498	0.536
LIG_FHA_1	484	490	PF00498	0.653
LIG_FHA_1	71	77	PF00498	0.378
LIG_FHA_2	522	528	PF00498	0.518
LIG_FHA_2	86	92	PF00498	0.308
LIG_IRF3_LxIS_1	386	393	PF10401	0.368
LIG_LIR_Apic_2	323	328	PF02991	0.598
LIG_LIR_Apic_2	52	58	PF02991	0.217
LIG_LIR_Apic_2	539	544	PF02991	0.485
LIG_LIR_Nem_3	113	119	PF02991	0.297
LIG_LIR_Nem_3	459	464	PF02991	0.562
LIG_LIR_Nem_3	64	69	PF02991	0.445
LIG_LIR_Nem_3	707	711	PF02991	0.624
LIG_PCNA_yPIPBox_3	143	154	PF02747	0.350
LIG_Pex14_2	172	176	PF04695	0.448
LIG_Pex14_2	65	69	PF04695	0.175
LIG_REV1ctd_RIR_1	63	72	PF16727	0.187
LIG_RPA_C_Fungi	333	345	PF08784	0.392
LIG_SH2_PTP2	541	544	PF00017	0.555
LIG_SH2_SRC	116	119	PF00017	0.247
LIG_SH2_SRC	541	544	PF00017	0.574
LIG_SH2_STAP1	214	218	PF00017	0.496
LIG_SH2_STAP1	441	445	PF00017	0.491
LIG_SH2_STAP1	86	90	PF00017	0.258
LIG_SH2_STAT5	116	119	PF00017	0.476
LIG_SH2_STAT5	14	17	PF00017	0.269
LIG_SH2_STAT5	36	39	PF00017	0.262
LIG_SH2_STAT5	541	544	PF00017	0.574
LIG_SH2_STAT5	723	726	PF00017	0.468
LIG_SH3_3	112	118	PF00018	0.260
LIG_SH3_3	255	261	PF00018	0.653
LIG_SH3_3	303	309	PF00018	0.471
LIG_SH3_3	381	387	PF00018	0.452
LIG_SH3_3	457	463	PF00018	0.500
LIG_SH3_3	468	474	PF00018	0.507
LIG_SH3_3	788	794	PF00018	0.581
LIG_SH3_3	826	832	PF00018	0.423
LIG_SUMO_SIM_anti_2	302	308	PF11976	0.522
LIG_TRAF2_1	795	798	PF00917	0.448
LIG_TRAF2_1	807	810	PF00917	0.431
LIG_TYR_ITIM	114	119	PF00017	0.252
LIG_UBA3_1	59	68	PF00899	0.188
MOD_CDC14_SPxK_1	198	201	PF00782	0.598
MOD_CDC14_SPxK_1	784	787	PF00782	0.536
MOD_CDK_SPxK_1	195	201	PF00069	0.603
MOD_CDK_SPxK_1	781	787	PF00069	0.525
MOD_CK1_1	192	198	PF00069	0.648
MOD_CK1_1	41	47	PF00069	0.233
MOD_CK1_1	50	56	PF00069	0.219
MOD_CK1_1	537	543	PF00069	0.518
MOD_CK1_1	551	557	PF00069	0.641
MOD_CK1_1	638	644	PF00069	0.504
MOD_CK1_1	704	710	PF00069	0.624
MOD_CK1_1	755	761	PF00069	0.641
MOD_CK1_1	777	783	PF00069	0.516
MOD_CK1_1	82	88	PF00069	0.239
MOD_CK1_1	834	840	PF00069	0.670
MOD_CK2_1	175	181	PF00069	0.572
MOD_CK2_1	347	353	PF00069	0.505
MOD_CK2_1	521	527	PF00069	0.457
MOD_CK2_1	804	810	PF00069	0.529
MOD_CK2_1	85	91	PF00069	0.265
MOD_CMANNOS	817	820	PF00535	0.402
MOD_GlcNHglycan	134	137	PF01048	0.293
MOD_GlcNHglycan	154	157	PF01048	0.487
MOD_GlcNHglycan	177	180	PF01048	0.615
MOD_GlcNHglycan	184	187	PF01048	0.656
MOD_GlcNHglycan	22	25	PF01048	0.288
MOD_GlcNHglycan	262	265	PF01048	0.738
MOD_GlcNHglycan	314	317	PF01048	0.552
MOD_GlcNHglycan	349	352	PF01048	0.538
MOD_GlcNHglycan	367	370	PF01048	0.573
MOD_GlcNHglycan	49	52	PF01048	0.272
MOD_GlcNHglycan	513	516	PF01048	0.566
MOD_GlcNHglycan	532	535	PF01048	0.558
MOD_GlcNHglycan	549	553	PF01048	0.506
MOD_GlcNHglycan	55	58	PF01048	0.191
MOD_GlcNHglycan	573	576	PF01048	0.610
MOD_GlcNHglycan	645	648	PF01048	0.647
MOD_GlcNHglycan	653	656	PF01048	0.619
MOD_GlcNHglycan	659	662	PF01048	0.619
MOD_GlcNHglycan	693	696	PF01048	0.666
MOD_GlcNHglycan	757	760	PF01048	0.674
MOD_GlcNHglycan	806	809	PF01048	0.546
MOD_GlcNHglycan	93	96	PF01048	0.298
MOD_GSK3_1	117	124	PF00069	0.343
MOD_GSK3_1	182	189	PF00069	0.531
MOD_GSK3_1	203	210	PF00069	0.559
MOD_GSK3_1	41	48	PF00069	0.257
MOD_GSK3_1	479	486	PF00069	0.656
MOD_GSK3_1	489	496	PF00069	0.557
MOD_GSK3_1	49	56	PF00069	0.243
MOD_GSK3_1	502	509	PF00069	0.615
MOD_GSK3_1	530	537	PF00069	0.570
MOD_GSK3_1	551	558	PF00069	0.573
MOD_GSK3_1	560	567	PF00069	0.558
MOD_GSK3_1	582	589	PF00069	0.542
MOD_GSK3_1	593	600	PF00069	0.409
MOD_GSK3_1	634	641	PF00069	0.539
MOD_GSK3_1	687	694	PF00069	0.566
MOD_GSK3_1	695	702	PF00069	0.531
MOD_GSK3_1	773	780	PF00069	0.599
MOD_GSK3_1	781	788	PF00069	0.642
MOD_GSK3_1	832	839	PF00069	0.468
MOD_NEK2_1	193	198	PF00069	0.762
MOD_NEK2_1	346	351	PF00069	0.427
MOD_NEK2_1	38	43	PF00069	0.248
MOD_NEK2_1	489	494	PF00069	0.533
MOD_NEK2_1	49	54	PF00069	0.230
MOD_NEK2_1	59	64	PF00069	0.303
MOD_NEK2_1	706	711	PF00069	0.665
MOD_NEK2_1	836	841	PF00069	0.475
MOD_NEK2_2	785	790	PF00069	0.511
MOD_PIKK_1	163	169	PF00454	0.480
MOD_PIKK_1	560	566	PF00454	0.608
MOD_PIKK_1	793	799	PF00454	0.465
MOD_PK_1	428	434	PF00069	0.498
MOD_PKA_2	26	32	PF00069	0.188
MOD_PKA_2	502	508	PF00069	0.580
MOD_PKA_2	530	536	PF00069	0.508
MOD_PKA_2	6	12	PF00069	0.244
MOD_PKA_2	657	663	PF00069	0.546
MOD_PKA_2	742	748	PF00069	0.564
MOD_PKA_2	752	758	PF00069	0.596
MOD_PKA_2	773	779	PF00069	0.651
MOD_PKA_2	82	88	PF00069	0.239
MOD_PKB_1	180	188	PF00069	0.506
MOD_PKB_1	751	759	PF00069	0.529
MOD_PKB_1	772	780	PF00069	0.461
MOD_Plk_1	189	195	PF00069	0.658
MOD_Plk_1	625	631	PF00069	0.509
MOD_Plk_1	684	690	PF00069	0.524
MOD_Plk_1	98	104	PF00069	0.325
MOD_Plk_2-3	543	549	PF00069	0.535
MOD_Plk_4	110	116	PF00069	0.271
MOD_Plk_4	537	543	PF00069	0.562
MOD_Plk_4	593	599	PF00069	0.612
MOD_Plk_4	61	67	PF00069	0.407
MOD_Plk_4	706	712	PF00069	0.501
MOD_Plk_4	774	780	PF00069	0.665
MOD_ProDKin_1	195	201	PF00069	0.670
MOD_ProDKin_1	249	255	PF00069	0.581
MOD_ProDKin_1	456	462	PF00069	0.429
MOD_ProDKin_1	463	469	PF00069	0.440
MOD_ProDKin_1	551	557	PF00069	0.619
MOD_ProDKin_1	569	575	PF00069	0.533
MOD_ProDKin_1	582	588	PF00069	0.637
MOD_ProDKin_1	701	707	PF00069	0.552
MOD_ProDKin_1	713	719	PF00069	0.413
MOD_ProDKin_1	781	787	PF00069	0.533
MOD_SUMO_rev_2	284	292	PF00179	0.598
TRG_DiLeu_BaLyEn_6	274	279	PF01217	0.522
TRG_ENDOCYTIC_2	116	119	PF00928	0.301
TRG_ENDOCYTIC_2	14	17	PF00928	0.323
TRG_ENDOCYTIC_2	214	217	PF00928	0.495
TRG_ER_diArg_1	143	145	PF00400	0.362
TRG_ER_diArg_1	265	267	PF00400	0.601
TRG_ER_diArg_1	335	338	PF00400	0.553
TRG_ER_diArg_1	396	398	PF00400	0.488
TRG_ER_diArg_1	425	428	PF00400	0.532
TRG_ER_diArg_1	445	447	PF00400	0.256
TRG_ER_diArg_1	5	8	PF00400	0.264
TRG_ER_diArg_1	606	608	PF00400	0.530
TRG_ER_diArg_1	610	612	PF00400	0.567
TRG_ER_diArg_1	733	736	PF00400	0.514
TRG_ER_diArg_1	781	783	PF00400	0.524
TRG_Pf-PMV_PEXEL_1	143	147	PF00026	0.434
TRG_Pf-PMV_PEXEL_1	338	342	PF00026	0.553
TRG_Pf-PMV_PEXEL_1	397	401	PF00026	0.551
TRG_Pf-PMV_PEXEL_1	446	451	PF00026	0.407
TRG_Pf-PMV_PEXEL_1	493	498	PF00026	0.386

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2Y8	Leptomonas seymouri	55%	100%
A0A0S4IQ31	Bodo saltans	29%	100%
A0A1X0P950	Trypanosomatidae	33%	100%
A0A3Q8IRK3	Leishmania donovani	99%	100%
A0A3R7MS13	Trypanosoma rangeli	33%	100%
A4HHP1	Leishmania braziliensis	76%	100%
E9AEA4	Leishmania major	86%	97%
E9ALI2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
V5BC37	Trypanosoma cruzi	33%	100%