LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I4Q5_LEIIN
TriTrypDb:
LINF_290027300
Length:
227

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I4Q5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I4Q5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 143 145 PF00675 0.676
CLV_NRD_NRD_1 187 189 PF00675 0.613
CLV_NRD_NRD_1 207 209 PF00675 0.469
CLV_NRD_NRD_1 221 223 PF00675 0.674
CLV_PCSK_KEX2_1 143 145 PF00082 0.676
CLV_PCSK_KEX2_1 187 189 PF00082 0.613
CLV_PCSK_KEX2_1 206 208 PF00082 0.480
CLV_PCSK_KEX2_1 223 225 PF00082 0.528
CLV_PCSK_PC1ET2_1 223 225 PF00082 0.491
CLV_PCSK_SKI1_1 29 33 PF00082 0.549
CLV_PCSK_SKI1_1 86 90 PF00082 0.436
DEG_APCC_DBOX_1 110 118 PF00400 0.534
DOC_CKS1_1 82 87 PF01111 0.446
DOC_CYCLIN_RxL_1 26 36 PF00134 0.467
DOC_PP4_FxxP_1 209 212 PF00568 0.576
DOC_PP4_MxPP_1 190 193 PF00568 0.597
DOC_USP7_MATH_1 161 165 PF00917 0.576
DOC_USP7_MATH_1 173 177 PF00917 0.513
DOC_USP7_MATH_1 54 58 PF00917 0.495
DOC_WW_Pin1_4 81 86 PF00397 0.595
LIG_14-3-3_CanoR_1 206 212 PF00244 0.582
LIG_BIR_II_1 1 5 PF00653 0.490
LIG_BRCT_BRCA1_1 163 167 PF00533 0.596
LIG_CSL_BTD_1 82 85 PF09270 0.456
LIG_FHA_1 38 44 PF00498 0.481
LIG_FHA_1 51 57 PF00498 0.423
LIG_HP1_1 137 141 PF01393 0.600
LIG_IRF3_LxIS_1 28 34 PF10401 0.453
LIG_LIR_Gen_1 164 173 PF02991 0.675
LIG_LIR_Nem_3 164 170 PF02991 0.678
LIG_NRP_CendR_1 224 227 PF00754 0.525
LIG_SH2_STAT5 55 58 PF00017 0.490
LIG_SH3_3 189 195 PF00018 0.598
LIG_SH3_3 210 216 PF00018 0.570
LIG_SUMO_SIM_anti_2 113 118 PF11976 0.514
LIG_SUMO_SIM_anti_2 76 82 PF11976 0.457
LIG_SUMO_SIM_par_1 29 34 PF11976 0.439
LIG_UBA3_1 166 174 PF00899 0.594
LIG_WW_3 191 195 PF00397 0.591
MOD_CDK_SPK_2 81 86 PF00069 0.455
MOD_CK1_1 2 8 PF00069 0.468
MOD_CK1_1 94 100 PF00069 0.537
MOD_CK2_1 128 134 PF00069 0.615
MOD_CK2_1 33 39 PF00069 0.665
MOD_GlcNHglycan 157 160 PF01048 0.589
MOD_GlcNHglycan 175 178 PF01048 0.475
MOD_GlcNHglycan 181 184 PF01048 0.559
MOD_GlcNHglycan 209 212 PF01048 0.576
MOD_GlcNHglycan 56 59 PF01048 0.478
MOD_GlcNHglycan 61 64 PF01048 0.415
MOD_GSK3_1 106 113 PF00069 0.535
MOD_GSK3_1 128 135 PF00069 0.614
MOD_GSK3_1 31 38 PF00069 0.650
MOD_GSK3_1 50 57 PF00069 0.394
MOD_NEK2_1 106 111 PF00069 0.527
MOD_NEK2_1 31 36 PF00069 0.617
MOD_NEK2_1 48 53 PF00069 0.435
MOD_NEK2_1 89 94 PF00069 0.475
MOD_NEK2_2 91 96 PF00069 0.499
MOD_PIKK_1 106 112 PF00454 0.534
MOD_PIKK_1 65 71 PF00454 0.580
MOD_PKA_1 207 213 PF00069 0.576
MOD_PKA_2 110 116 PF00069 0.543
MOD_PKA_2 207 213 PF00069 0.576
MOD_Plk_4 110 116 PF00069 0.504
MOD_ProDKin_1 81 87 PF00069 0.585
MOD_SUMO_rev_2 34 43 PF00179 0.566
TRG_DiLeu_BaLyEn_6 27 32 PF01217 0.476
TRG_ER_diArg_1 143 145 PF00400 0.685
TRG_ER_diArg_1 187 189 PF00400 0.613
TRG_ER_diArg_1 206 208 PF00400 0.480
TRG_ER_diArg_1 27 30 PF00400 0.499
TRG_NLS_Bipartite_1 187 207 PF00514 0.597
TRG_NLS_MonoExtC_3 202 207 PF00514 0.600

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7X2Q7 Leishmania donovani 100% 85%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS