Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I4Q2_LEIIN

TriTrypDb:

LINF_290027000

Length:

206

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I4Q2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I4Q2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	10	12	PF00675	0.617
CLV_NRD_NRD_1	156	158	PF00675	0.649
CLV_PCSK_KEX2_1	10	12	PF00082	0.617
CLV_PCSK_KEX2_1	156	158	PF00082	0.658
CLV_PCSK_SKI1_1	10	14	PF00082	0.558
CLV_PCSK_SKI1_1	124	128	PF00082	0.437
CLV_PCSK_SKI1_1	134	138	PF00082	0.528
CLV_PCSK_SKI1_1	199	203	PF00082	0.681
CLV_PCSK_SKI1_1	4	8	PF00082	0.641
DEG_Nend_UBRbox_3	1	3	PF02207	0.621
DOC_PP1_RVXF_1	197	204	PF00149	0.678
DOC_PP2B_LxvP_1	98	101	PF13499	0.594
DOC_USP7_MATH_1	21	25	PF00917	0.690
DOC_USP7_MATH_1	81	85	PF00917	0.720
DOC_USP7_MATH_2	65	71	PF00917	0.775
DOC_USP7_UBL2_3	191	195	PF12436	0.660
DOC_WW_Pin1_4	102	107	PF00397	0.626
DOC_WW_Pin1_4	32	37	PF00397	0.804
DOC_WW_Pin1_4	47	52	PF00397	0.769
LIG_14-3-3_CanoR_1	10	19	PF00244	0.592
LIG_14-3-3_CanoR_1	29	34	PF00244	0.798
LIG_deltaCOP1_diTrp_1	158	166	PF00928	0.643
LIG_FHA_1	125	131	PF00498	0.467
LIG_FHA_2	77	83	PF00498	0.844
LIG_FHA_2	92	98	PF00498	0.530
LIG_HP1_1	21	25	PF01393	0.615
LIG_LIR_Apic_2	32	36	PF02991	0.800
LIG_LIR_Gen_1	158	169	PF02991	0.636
LIG_LIR_Gen_1	200	206	PF02991	0.474
LIG_LIR_Nem_3	110	115	PF02991	0.531
LIG_LIR_Nem_3	158	164	PF02991	0.645
LIG_LIR_Nem_3	200	206	PF02991	0.474
LIG_LIR_Nem_3	35	41	PF02991	0.818
LIG_MYND_1	51	55	PF01753	0.836
LIG_PDZ_Class_2	201	206	PF00595	0.694
LIG_RPA_C_Fungi	6	18	PF08784	0.612
LIG_SH2_CRK	33	37	PF00017	0.804
LIG_SH2_GRB2like	109	112	PF00017	0.677
LIG_SH2_GRB2like	115	118	PF00017	0.518
LIG_SH2_GRB2like	41	44	PF00017	0.831
LIG_SH2_NCK_1	33	37	PF00017	0.804
LIG_SH2_SRC	115	118	PF00017	0.615
LIG_SH2_STAP1	119	123	PF00017	0.608
LIG_SH2_STAP1	41	45	PF00017	0.656
LIG_SH2_STAT5	115	118	PF00017	0.615
LIG_SH2_STAT5	122	125	PF00017	0.449
LIG_SH2_STAT5	159	162	PF00017	0.650
LIG_SH2_STAT5	38	41	PF00017	0.796
LIG_SH3_3	15	21	PF00018	0.689
LIG_SH3_3	45	51	PF00018	0.756
LIG_SH3_3	98	104	PF00018	0.704
LIG_SUMO_SIM_par_1	21	27	PF11976	0.618
LIG_WRC_WIRS_1	160	165	PF05994	0.638
MOD_CK1_1	24	30	PF00069	0.660
MOD_CK1_1	32	38	PF00069	0.687
MOD_CK1_1	66	72	PF00069	0.776
MOD_CK1_1	75	81	PF00069	0.755
MOD_GlcNHglycan	131	134	PF01048	0.628
MOD_GlcNHglycan	15	18	PF01048	0.660
MOD_GlcNHglycan	43	46	PF01048	0.648
MOD_GlcNHglycan	56	59	PF01048	0.813
MOD_GlcNHglycan	82	86	PF01048	0.696
MOD_GSK3_1	32	39	PF00069	0.809
MOD_GSK3_1	63	70	PF00069	0.769
MOD_GSK3_1	72	79	PF00069	0.706
MOD_LATS_1	8	14	PF00433	0.564
MOD_NEK2_1	129	134	PF00069	0.572
MOD_NEK2_2	21	26	PF00069	0.691
MOD_NEK2_2	36	41	PF00069	0.820
MOD_PIKK_1	124	130	PF00454	0.620
MOD_PIKK_1	174	180	PF00454	0.630
MOD_PKA_1	10	16	PF00069	0.607
MOD_PKA_2	10	16	PF00069	0.575
MOD_PKA_2	183	189	PF00069	0.541
MOD_PKA_2	75	81	PF00069	0.670
MOD_PKB_1	29	37	PF00069	0.754
MOD_Plk_1	124	130	PF00069	0.620
MOD_Plk_1	66	72	PF00069	0.657
MOD_Plk_2-3	91	97	PF00069	0.787
MOD_Plk_4	36	42	PF00069	0.665
MOD_ProDKin_1	102	108	PF00069	0.627
MOD_ProDKin_1	32	38	PF00069	0.807
MOD_ProDKin_1	47	53	PF00069	0.772
TRG_ER_diArg_1	155	157	PF00400	0.651
TRG_ER_diArg_1	9	11	PF00400	0.695

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IF97	Leishmania donovani	100%	68%
E9AE55	Leishmania major	91%	100%
E9ALN0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%