C2H2-type domain-containing protein

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I4P5_LEIIN

TriTrypDb:

LINF_290026300

Length:

108

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	7
GO:0005737	cytoplasm	2	7
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0043229	intracellular organelle	3	7
GO:0043231	intracellular membrane-bounded organelle	4	7
GO:0110165	cellular anatomical entity	1	7

Phosphorylation

Amastigote: 24

Expansion

Sequence features

A4I4P5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I4P5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	16	18	PF00675	0.453
CLV_NRD_NRD_1	35	37	PF00675	0.442
DOC_CDC14_PxL_1	52	60	PF14671	0.383
DOC_PP1_RVXF_1	60	66	PF00149	0.462
DOC_USP7_MATH_1	41	45	PF00917	0.374
DOC_USP7_UBL2_3	101	105	PF12436	0.558
DOC_USP7_UBL2_3	45	49	PF12436	0.408
LIG_APCC_ABBA_1	61	66	PF00400	0.398
LIG_FHA_1	88	94	PF00498	0.460
LIG_FHA_2	71	77	PF00498	0.441
LIG_FHA_2	9	15	PF00498	0.432
LIG_LIR_Gen_1	76	86	PF02991	0.427
LIG_LIR_Nem_3	76	82	PF02991	0.426
LIG_OCRL_FandH_1	78	90	PF00620	0.419
MOD_CK2_1	70	76	PF00069	0.436
MOD_CK2_1	8	14	PF00069	0.460
MOD_GlcNHglycan	29	32	PF01048	0.447
MOD_GSK3_1	8	15	PF00069	0.456
MOD_N-GLC_1	70	75	PF02516	0.432
MOD_NEK2_1	21	26	PF00069	0.478
MOD_Plk_1	70	76	PF00069	0.511
TRG_ER_diLys_1	103	108	PF00400	0.579

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PB71	Leptomonas seymouri	86%	100%
A0A3S7X2P5	Leishmania donovani	98%	100%
A4HHI7	Leishmania braziliensis	91%	100%
E9AE48	Leishmania major	99%	100%
E9ALN7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
Q9FFD8	Arabidopsis thaliana	48%	100%
Q9M8S0	Arabidopsis thaliana	47%	100%