LeishMANIAdb
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Putative histone H2A

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Putative histone H2A
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania infantum
UniProt:
A4I4N3_LEIIN
TriTrypDb:
Length:
147

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I4N3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I4N3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 11 13 PF00675 0.720
CLV_NRD_NRD_1 28 30 PF00675 0.604
CLV_NRD_NRD_1 73 75 PF00675 0.685
CLV_NRD_NRD_1 88 90 PF00675 0.639
CLV_PCSK_KEX2_1 10 12 PF00082 0.720
CLV_PCSK_KEX2_1 28 30 PF00082 0.594
CLV_PCSK_KEX2_1 72 74 PF00082 0.685
CLV_PCSK_KEX2_1 88 90 PF00082 0.629
CLV_PCSK_PC7_1 24 30 PF00082 0.787
DEG_Nend_Nbox_1 1 3 PF02207 0.570
DOC_WW_Pin1_4 18 23 PF00397 0.663
LIG_14-3-3_CanoR_1 76 85 PF00244 0.653
LIG_14-3-3_CterR_2 143 147 PF00244 0.560
LIG_FHA_1 108 114 PF00498 0.700
LIG_HCF-1_HBM_1 114 117 PF13415 0.633
LIG_LIR_Nem_3 114 120 PF02991 0.623
LIG_LYPXL_yS_3 117 120 PF13949 0.620
LIG_SH3_2 6 11 PF14604 0.697
LIG_SH3_3 16 22 PF00018 0.559
LIG_SH3_3 3 9 PF00018 0.809
LIG_SH3_3 56 62 PF00018 0.792
LIG_TRAF2_1 78 81 PF00917 0.799
MOD_CDC14_SPxK_1 21 24 PF00782 0.656
MOD_CDK_SPxK_1 18 24 PF00069 0.663
MOD_GSK3_1 133 140 PF00069 0.528
MOD_NEK2_1 113 118 PF00069 0.626
MOD_PIKK_1 83 89 PF00454 0.789
MOD_PKA_2 137 143 PF00069 0.531
MOD_PKB_1 74 82 PF00069 0.656
MOD_Plk_1 113 119 PF00069 0.624
MOD_ProDKin_1 18 24 PF00069 0.663
TRG_DiLeu_BaEn_1 80 85 PF01217 0.653
TRG_ENDOCYTIC_2 117 120 PF00928 0.620
TRG_ER_diArg_1 27 29 PF00400 0.606
TRG_ER_diArg_1 71 74 PF00400 0.796
TRG_ER_diArg_1 9 12 PF00400 0.716
TRG_Pf-PMV_PEXEL_1 82 87 PF00026 0.647

Homologs

Protein Taxonomy Sequence identity Coverage
A4I4N4 Leishmania infantum 98% 76%
E9AV76 Leishmania mexicana (strain MHOM/GT/2001/U1103) 77% 82%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS