Putative Zn-finger domain protein

Quick info Annotations Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Zn-finger domain protein - putative

Species:

Leishmania infantum

UniProt:

A4I4M7_LEIIN

TriTrypDb:

LINF_290023200

Length:

1217

Annotations

Annotations by Jardim et al.

Protein modification, E3 ubiquitin- ligase, putative Zn-finger domain

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Show entries

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

Previous1Next

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4I4M7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I4M7

Function

Could not find GO biological_process term for this entry.

Show entries

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	7
GO:0008270	zinc ion binding	6	7
GO:0043167	ion binding	2	7
GO:0043169	cation binding	3	7
GO:0046872	metal ion binding	4	7
GO:0046914	transition metal ion binding	5	7

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1163	1167	PF00656	0.398
CLV_C14_Caspase3-7	1178	1182	PF00656	0.512
CLV_C14_Caspase3-7	1202	1206	PF00656	0.393
CLV_C14_Caspase3-7	367	371	PF00656	0.636
CLV_C14_Caspase3-7	389	393	PF00656	0.735
CLV_C14_Caspase3-7	411	415	PF00656	0.484
CLV_C14_Caspase3-7	867	871	PF00656	0.491
CLV_NRD_NRD_1	1029	1031	PF00675	0.339
CLV_NRD_NRD_1	1046	1048	PF00675	0.299
CLV_NRD_NRD_1	13	15	PF00675	0.500

Previous1 2 3 4 5…42Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P944	Leptomonas seymouri	45%	97%
A0A3S7X2J0	Leishmania donovani	99%	100%
A4HHH7	Leishmania braziliensis	77%	100%
E9AE25	Leishmania major	95%	100%
E9ALQ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%

Previous1Next