CLASP_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I4F4_LEIIN

TriTrypDb:

LINF_290015400

Length:

432

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I4F4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I4F4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	12	16	PF00656	0.686
CLV_C14_Caspase3-7	265	269	PF00656	0.762
CLV_C14_Caspase3-7	273	277	PF00656	0.765
CLV_C14_Caspase3-7	405	409	PF00656	0.738
CLV_NRD_NRD_1	189	191	PF00675	0.705
CLV_NRD_NRD_1	228	230	PF00675	0.721
CLV_NRD_NRD_1	67	69	PF00675	0.707
CLV_PCSK_KEX2_1	123	125	PF00082	0.643
CLV_PCSK_KEX2_1	228	230	PF00082	0.721
CLV_PCSK_KEX2_1	67	69	PF00082	0.707
CLV_PCSK_PC1ET2_1	123	125	PF00082	0.699
CLV_PCSK_SKI1_1	151	155	PF00082	0.728
CLV_PCSK_SKI1_1	328	332	PF00082	0.759
CLV_PCSK_SKI1_1	401	405	PF00082	0.819
CLV_PCSK_SKI1_1	49	53	PF00082	0.717
CLV_PCSK_SKI1_1	61	65	PF00082	0.822
DOC_CKS1_1	309	314	PF01111	0.758
DOC_CKS1_1	410	415	PF01111	0.743
DOC_MAPK_gen_1	35	45	PF00069	0.685
DOC_MAPK_MEF2A_6	141	149	PF00069	0.601
DOC_PP1_RVXF_1	304	311	PF00149	0.739
DOC_PP1_RVXF_1	39	46	PF00149	0.686
DOC_PP2B_LxvP_1	176	179	PF13499	0.732
DOC_PP2B_LxvP_1	347	350	PF13499	0.755
DOC_USP7_MATH_1	155	159	PF00917	0.809
DOC_USP7_MATH_1	179	183	PF00917	0.649
DOC_USP7_MATH_1	19	23	PF00917	0.804
DOC_USP7_MATH_1	284	288	PF00917	0.784
DOC_USP7_MATH_1	375	379	PF00917	0.706
DOC_WW_Pin1_4	114	119	PF00397	0.754
DOC_WW_Pin1_4	163	168	PF00397	0.721
DOC_WW_Pin1_4	182	187	PF00397	0.508
DOC_WW_Pin1_4	214	219	PF00397	0.673
DOC_WW_Pin1_4	267	272	PF00397	0.717
DOC_WW_Pin1_4	280	285	PF00397	0.682
DOC_WW_Pin1_4	308	313	PF00397	0.841
DOC_WW_Pin1_4	315	320	PF00397	0.581
DOC_WW_Pin1_4	328	333	PF00397	0.688
DOC_WW_Pin1_4	409	414	PF00397	0.752
LIG_14-3-3_CanoR_1	124	133	PF00244	0.682
LIG_14-3-3_CanoR_1	156	164	PF00244	0.675
LIG_14-3-3_CanoR_1	200	205	PF00244	0.675
LIG_14-3-3_CanoR_1	228	236	PF00244	0.758
LIG_14-3-3_CanoR_1	401	410	PF00244	0.807
LIG_14-3-3_CanoR_1	416	424	PF00244	0.590
LIG_14-3-3_CanoR_1	74	82	PF00244	0.625
LIG_Actin_WH2_2	36	54	PF00022	0.721
LIG_BRCT_BRCA1_1	184	188	PF00533	0.753
LIG_BRCT_BRCA1_1	353	357	PF00533	0.812
LIG_deltaCOP1_diTrp_1	77	82	PF00928	0.721
LIG_FHA_1	117	123	PF00498	0.677
LIG_FHA_1	157	163	PF00498	0.707
LIG_FHA_1	171	177	PF00498	0.770
LIG_FHA_1	303	309	PF00498	0.754
LIG_FHA_1	342	348	PF00498	0.787
LIG_FHA_1	405	411	PF00498	0.711
LIG_FHA_1	425	431	PF00498	0.625
LIG_FHA_1	54	60	PF00498	0.801
LIG_FHA_2	416	422	PF00498	0.655
LIG_FHA_2	52	58	PF00498	0.723
LIG_GBD_Chelix_1	43	51	PF00786	0.782
LIG_LIR_Gen_1	100	109	PF02991	0.703
LIG_LIR_Nem_3	100	105	PF02991	0.707
LIG_LIR_Nem_3	388	392	PF02991	0.761
LIG_MYND_1	214	218	PF01753	0.697
LIG_SH2_CRK	254	258	PF00017	0.722
LIG_SH2_NCK_1	111	115	PF00017	0.621
LIG_SH2_STAP1	111	115	PF00017	0.646
LIG_SH3_2	186	191	PF14604	0.599
LIG_SH3_3	133	139	PF00018	0.725
LIG_SH3_3	183	189	PF00018	0.673
LIG_SH3_3	212	218	PF00018	0.697
LIG_SH3_3	238	244	PF00018	0.743
LIG_SxIP_EBH_1	328	342	PF03271	0.635
LIG_TRAF2_1	75	78	PF00917	0.721
LIG_TRAF2_2	350	355	PF00917	0.734
LIG_TYR_ITIM	109	114	PF00017	0.615
MOD_CDC14_SPxK_1	283	286	PF00782	0.760
MOD_CDC14_SPxK_1	318	321	PF00782	0.775
MOD_CDK_SPK_2	328	333	PF00069	0.773
MOD_CDK_SPxK_1	280	286	PF00069	0.762
MOD_CDK_SPxK_1	315	321	PF00069	0.837
MOD_CDK_SPxxK_3	308	315	PF00069	0.738
MOD_CDK_SPxxK_3	409	416	PF00069	0.817
MOD_CK1_1	127	133	PF00069	0.635
MOD_CK1_1	165	171	PF00069	0.718
MOD_CK1_1	182	188	PF00069	0.586
MOD_CK1_1	196	202	PF00069	0.596
MOD_CK1_1	203	209	PF00069	0.659
MOD_CK1_1	22	28	PF00069	0.697
MOD_CK1_1	262	268	PF00069	0.663
MOD_CK1_1	279	285	PF00069	0.653
MOD_CK1_1	323	329	PF00069	0.802
MOD_CK1_1	368	374	PF00069	0.731
MOD_CK1_1	395	401	PF00069	0.719
MOD_CK1_1	9	15	PF00069	0.794
MOD_CK2_1	165	171	PF00069	0.729
MOD_CK2_1	22	28	PF00069	0.821
MOD_CK2_1	415	421	PF00069	0.711
MOD_CK2_1	51	57	PF00069	0.738
MOD_CK2_1	72	78	PF00069	0.600
MOD_Cter_Amidation	65	68	PF01082	0.747
MOD_DYRK1A_RPxSP_1	328	332	PF00069	0.737
MOD_GlcNHglycan	106	109	PF01048	0.577
MOD_GlcNHglycan	15	18	PF01048	0.669
MOD_GlcNHglycan	151	154	PF01048	0.715
MOD_GlcNHglycan	167	170	PF01048	0.628
MOD_GlcNHglycan	181	184	PF01048	0.596
MOD_GlcNHglycan	24	27	PF01048	0.720
MOD_GlcNHglycan	379	382	PF01048	0.663
MOD_GlcNHglycan	82	85	PF01048	0.758
MOD_GSK3_1	151	158	PF00069	0.727
MOD_GSK3_1	165	172	PF00069	0.797
MOD_GSK3_1	195	202	PF00069	0.674
MOD_GSK3_1	20	27	PF00069	0.619
MOD_GSK3_1	228	235	PF00069	0.832
MOD_GSK3_1	262	269	PF00069	0.784
MOD_GSK3_1	276	283	PF00069	0.841
MOD_GSK3_1	311	318	PF00069	0.803
MOD_GSK3_1	331	338	PF00069	0.789
MOD_GSK3_1	364	371	PF00069	0.723
MOD_GSK3_1	9	16	PF00069	0.678
MOD_N-GLC_1	302	307	PF02516	0.733
MOD_N-GLC_1	375	380	PF02516	0.741
MOD_NEK2_1	266	271	PF00069	0.735
MOD_NEK2_1	364	369	PF00069	0.809
MOD_NEK2_1	402	407	PF00069	0.762
MOD_NEK2_1	6	11	PF00069	0.728
MOD_PIKK_1	392	398	PF00454	0.723
MOD_PKA_1	228	234	PF00069	0.720
MOD_PKA_2	155	161	PF00069	0.660
MOD_PKA_2	199	205	PF00069	0.714
MOD_PKA_2	228	234	PF00069	0.743
MOD_PKA_2	244	250	PF00069	0.637
MOD_PKA_2	285	291	PF00069	0.763
MOD_PKA_2	359	365	PF00069	0.774
MOD_PKA_2	415	421	PF00069	0.680
MOD_PKA_2	424	430	PF00069	0.797
MOD_PKA_2	73	79	PF00069	0.729
MOD_Plk_1	170	176	PF00069	0.705
MOD_Plk_1	20	26	PF00069	0.705
MOD_Plk_1	232	238	PF00069	0.735
MOD_Plk_1	375	381	PF00069	0.739
MOD_Plk_4	343	349	PF00069	0.735
MOD_Plk_4	359	365	PF00069	0.530
MOD_ProDKin_1	114	120	PF00069	0.756
MOD_ProDKin_1	163	169	PF00069	0.719
MOD_ProDKin_1	182	188	PF00069	0.510
MOD_ProDKin_1	214	220	PF00069	0.677
MOD_ProDKin_1	267	273	PF00069	0.719
MOD_ProDKin_1	280	286	PF00069	0.684
MOD_ProDKin_1	308	314	PF00069	0.840
MOD_ProDKin_1	315	321	PF00069	0.584
MOD_ProDKin_1	328	334	PF00069	0.688
MOD_ProDKin_1	409	415	PF00069	0.753
MOD_SUMO_rev_2	48	54	PF00179	0.786
TRG_DiLeu_BaLyEn_6	215	220	PF01217	0.705
TRG_DiLeu_BaLyEn_6	426	431	PF01217	0.730
TRG_ENDOCYTIC_2	111	114	PF00928	0.613
TRG_ER_diArg_1	228	230	PF00400	0.721
TRG_ER_diArg_1	91	94	PF00400	0.612
TRG_Pf-PMV_PEXEL_1	228	233	PF00026	0.784
TRG_Pf-PMV_PEXEL_1	237	242	PF00026	0.744
TRG_Pf-PMV_PEXEL_1	49	53	PF00026	0.787

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8D7	Leptomonas seymouri	42%	100%
A0A3Q8IFA6	Leishmania donovani	99%	100%
A4HHA8	Leishmania braziliensis	70%	99%
E9ADV4	Leishmania major	90%	100%
E9ALX6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%