Putative A-1 protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

A-1 protein - putative

Species:

Leishmania infantum

UniProt:

A4I4F1_LEIIN

TriTrypDb:

LINF_290015100

Length:

175

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I4F1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I4F1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	154	156	PF00675	0.642
CLV_NRD_NRD_1	4	6	PF00675	0.687
CLV_PCSK_KEX2_1	6	8	PF00082	0.661
CLV_PCSK_KEX2_1	64	66	PF00082	0.559
CLV_PCSK_PC1ET2_1	6	8	PF00082	0.661
CLV_PCSK_PC1ET2_1	64	66	PF00082	0.559
CLV_PCSK_SKI1_1	156	160	PF00082	0.611
CLV_PCSK_SKI1_1	76	80	PF00082	0.620
CLV_PCSK_SKI1_1	92	96	PF00082	0.524
DEG_Nend_UBRbox_2	1	3	PF02207	0.688
DEG_SPOP_SBC_1	44	48	PF00917	0.612
DOC_CYCLIN_RxL_1	153	162	PF00134	0.525
DOC_PP2B_LxvP_1	121	124	PF13499	0.571
DOC_USP7_MATH_1	137	141	PF00917	0.653
DOC_USP7_MATH_1	44	48	PF00917	0.675
DOC_WW_Pin1_4	45	50	PF00397	0.610
LIG_14-3-3_CanoR_1	65	73	PF00244	0.567
LIG_Dynein_DLC8_1	140	146	PF01221	0.664
LIG_FHA_1	65	71	PF00498	0.515
LIG_FHA_2	142	148	PF00498	0.654
LIG_FHA_2	46	52	PF00498	0.745
LIG_FHA_2	88	94	PF00498	0.671
LIG_Integrin_RGD_1	18	20	PF01839	0.545
LIG_LIR_Gen_1	164	174	PF02991	0.555
LIG_LIR_Gen_1	56	63	PF02991	0.578
LIG_LIR_Nem_3	164	170	PF02991	0.544
LIG_LIR_Nem_3	56	62	PF02991	0.583
LIG_NRBOX	165	171	PF00104	0.505
LIG_PTB_Apo_2	103	110	PF02174	0.493
LIG_SH2_CRK	167	171	PF00017	0.505
LIG_SH2_CRK	59	63	PF00017	0.561
LIG_SH2_STAP1	59	63	PF00017	0.604
LIG_SH2_STAT5	167	170	PF00017	0.643
LIG_SxIP_EBH_1	40	49	PF03271	0.615
LIG_TRAF2_1	48	51	PF00917	0.607
LIG_TRAF2_1	83	86	PF00917	0.667
MOD_CK1_1	117	123	PF00069	0.547
MOD_CK1_1	148	154	PF00069	0.557
MOD_CK1_1	38	44	PF00069	0.646
MOD_CK2_1	141	147	PF00069	0.660
MOD_CK2_1	44	50	PF00069	0.654
MOD_CK2_1	87	93	PF00069	0.673
MOD_GlcNHglycan	116	119	PF01048	0.562
MOD_GlcNHglycan	20	26	PF01048	0.646
MOD_GlcNHglycan	40	43	PF01048	0.768
MOD_GSK3_1	137	144	PF00069	0.583
MOD_GSK3_1	161	168	PF00069	0.443
MOD_GSK3_1	92	99	PF00069	0.699
MOD_N-GLC_1	10	15	PF02516	0.610
MOD_NEK2_1	36	41	PF00069	0.541
MOD_PIKK_1	141	147	PF00454	0.660
MOD_PIKK_1	87	93	PF00454	0.644
MOD_PKA_1	64	70	PF00069	0.558
MOD_PKA_2	138	144	PF00069	0.619
MOD_PKA_2	64	70	PF00069	0.558
MOD_Plk_4	117	123	PF00069	0.569
MOD_Plk_4	165	171	PF00069	0.619
MOD_ProDKin_1	45	51	PF00069	0.610
TRG_DiLeu_BaEn_1	165	170	PF01217	0.503
TRG_ENDOCYTIC_2	167	170	PF00928	0.501
TRG_ENDOCYTIC_2	59	62	PF00928	0.566
TRG_NLS_MonoExtC_3	4	9	PF00514	0.664
TRG_NLS_MonoExtN_4	5	10	PF00514	0.665

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X2A2	Leishmania donovani	99%	100%
A4HHA5	Leishmania braziliensis	75%	100%
E9ADV1	Leishmania major	92%	100%
E9ALX9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%