LeishMANIAdb
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Putative ras-like small GTPases

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative ras-like small GTPases
Gene product:
small GTP-binding protein - putative
Species:
Leishmania infantum
UniProt:
A4I446_LEIIN
TriTrypDb:
LINF_290005800
Length:
186

Annotations

Annotations by Jardim et al.

Intracellular protein trafficking, ras-like small GTPases

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 25
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 16
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0005768 endosome 7 1
GO:0005794 Golgi apparatus 5 1
GO:0005815 microtubule organizing center 2 1
GO:0005929 cilium 4 2
GO:0030990 intraciliary transport particle 2 1
GO:0031410 cytoplasmic vesicle 6 1
GO:0031982 vesicle 4 1
GO:0032991 protein-containing complex 1 1
GO:0036064 ciliary basal body 3 1
GO:0042995 cell projection 2 2
GO:0043226 organelle 2 2
GO:0043227 membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0097708 intracellular vesicle 5 1
GO:0110165 cellular anatomical entity 1 2
GO:0120025 plasma membrane bounded cell projection 3 2

Expansion

Sequence features

A4I446
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I446

Function

Biological processes
Term Name Level Count
GO:0006810 transport 3 2
GO:0007017 microtubule-based process 2 2
GO:0007018 microtubule-based movement 3 2
GO:0009987 cellular process 1 2
GO:0010970 transport along microtubule 4 2
GO:0030705 cytoskeleton-dependent intracellular transport 4 2
GO:0031344 regulation of cell projection organization 5 1
GO:0031503 protein-containing complex localization 2 2
GO:0033043 regulation of organelle organization 5 1
GO:0035735 intraciliary transport involved in cilium assembly 4 1
GO:0042073 intraciliary transport 3 2
GO:0044087 regulation of cellular component biogenesis 4 1
GO:0046907 intracellular transport 3 2
GO:0050789 regulation of biological process 2 1
GO:0050794 regulation of cellular process 3 1
GO:0051128 regulation of cellular component organization 4 1
GO:0051179 localization 1 2
GO:0051234 establishment of localization 2 2
GO:0051641 cellular localization 2 2
GO:0051649 establishment of localization in cell 3 2
GO:0060491 regulation of cell projection assembly 5 1
GO:0065007 biological regulation 1 1
GO:0099111 microtubule-based transport 4 2
GO:0120032 regulation of plasma membrane bounded cell projection assembly 6 1
GO:0120035 regulation of plasma membrane bounded cell projection organization 6 1
GO:1902017 regulation of cilium assembly 6 1
GO:1902115 regulation of organelle assembly 5 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 11
GO:0003824 catalytic activity 1 11
GO:0003924 GTPase activity 7 11
GO:0005488 binding 1 11
GO:0005525 GTP binding 5 11
GO:0016462 pyrophosphatase activity 5 11
GO:0016787 hydrolase activity 2 11
GO:0016817 hydrolase activity, acting on acid anhydrides 3 11
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 11
GO:0017076 purine nucleotide binding 4 11
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 11
GO:0019001 guanyl nucleotide binding 5 11
GO:0032553 ribonucleotide binding 3 11
GO:0032555 purine ribonucleotide binding 4 11
GO:0032561 guanyl ribonucleotide binding 5 11
GO:0035639 purine ribonucleoside triphosphate binding 4 11
GO:0036094 small molecule binding 2 11
GO:0043167 ion binding 2 11
GO:0043168 anion binding 3 11
GO:0097159 organic cyclic compound binding 2 11
GO:0097367 carbohydrate derivative binding 2 11
GO:1901265 nucleoside phosphate binding 3 11
GO:1901363 heterocyclic compound binding 2 11

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 129 133 PF00656 0.361
CLV_NRD_NRD_1 99 101 PF00675 0.379
CLV_PCSK_KEX2_1 174 176 PF00082 0.398
CLV_PCSK_PC1ET2_1 174 176 PF00082 0.397
CLV_PCSK_SKI1_1 101 105 PF00082 0.338
CLV_PCSK_SKI1_1 107 111 PF00082 0.326
CLV_PCSK_SKI1_1 166 170 PF00082 0.485
CLV_PCSK_SKI1_1 18 22 PF00082 0.301
DOC_CYCLIN_yClb1_LxF_4 141 147 PF00134 0.414
DOC_MAPK_gen_1 107 116 PF00069 0.363
DOC_USP7_MATH_2 160 166 PF00917 0.310
DOC_USP7_UBL2_3 101 105 PF12436 0.414
LIG_14-3-3_CanoR_1 72 81 PF00244 0.414
LIG_BRCT_BRCA1_1 164 168 PF00533 0.310
LIG_FHA_1 153 159 PF00498 0.424
LIG_FHA_1 17 23 PF00498 0.320
LIG_FHA_1 54 60 PF00498 0.328
LIG_LIR_Gen_1 19 25 PF02991 0.284
LIG_LIR_Gen_1 82 90 PF02991 0.309
LIG_LIR_Nem_3 82 87 PF02991 0.361
LIG_REV1ctd_RIR_1 144 152 PF16727 0.414
LIG_SH2_SRC 77 80 PF00017 0.356
LIG_SH2_STAT5 36 39 PF00017 0.301
LIG_SH2_STAT5 77 80 PF00017 0.310
LIG_SH3_3 8 14 PF00018 0.354
LIG_SUMO_SIM_anti_2 58 63 PF11976 0.365
LIG_SUMO_SIM_par_1 52 60 PF11976 0.414
LIG_UBA3_1 113 121 PF00899 0.361
MOD_CK1_1 16 22 PF00069 0.387
MOD_CK1_1 180 186 PF00069 0.507
MOD_CK1_1 27 33 PF00069 0.319
MOD_GlcNHglycan 149 152 PF01048 0.326
MOD_GlcNHglycan 15 18 PF01048 0.349
MOD_GlcNHglycan 182 185 PF01048 0.456
MOD_GlcNHglycan 81 84 PF01048 0.491
MOD_GSK3_1 101 108 PF00069 0.345
MOD_GSK3_1 12 19 PF00069 0.300
MOD_GSK3_1 53 60 PF00069 0.406
MOD_GSK3_1 88 95 PF00069 0.330
MOD_N-GLC_1 27 32 PF02516 0.408
MOD_NEK2_1 147 152 PF00069 0.369
MOD_NEK2_1 24 29 PF00069 0.282
MOD_PIKK_1 177 183 PF00454 0.476
MOD_PKA_2 152 158 PF00069 0.414
MOD_PKA_2 162 168 PF00069 0.414
MOD_PKA_2 71 77 PF00069 0.414
MOD_Plk_1 53 59 PF00069 0.300
MOD_Plk_2-3 53 59 PF00069 0.326
MOD_Plk_4 142 148 PF00069 0.441
MOD_Plk_4 27 33 PF00069 0.439
MOD_Plk_4 57 63 PF00069 0.361
TRG_ENDOCYTIC_2 70 73 PF00928 0.305
TRG_ER_diArg_1 4 7 PF00400 0.470
TRG_NES_CRM1_1 112 126 PF08389 0.414

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P2Z9 Leptomonas seymouri 30% 79%
A0A0N0P3A0 Leptomonas seymouri 30% 69%
A0A0N0P3G2 Leptomonas seymouri 85% 100%
A0A0N0P6K4 Leptomonas seymouri 24% 86%
A0A0N0P6P8 Leptomonas seymouri 29% 89%
A0A0N0P8G7 Leptomonas seymouri 28% 86%
A0A0N0P8I1 Leptomonas seymouri 29% 84%
A0A0N1HYV5 Leptomonas seymouri 23% 86%
A0A0N1I011 Leptomonas seymouri 28% 92%
A0A0N1I9K4 Leptomonas seymouri 22% 79%
A0A0N1IJ36 Leptomonas seymouri 32% 84%
A0A0N1IL60 Leptomonas seymouri 27% 90%
A0A0N1ILN4 Leptomonas seymouri 26% 93%
A0A0N1PC08 Leptomonas seymouri 27% 90%
A0A0S4IJB7 Bodo saltans 22% 85%
A0A0S4IM06 Bodo saltans 28% 85%
A0A0S4IWV0 Bodo saltans 31% 89%
A0A0S4IX77 Bodo saltans 29% 93%
A0A0S4IY79 Bodo saltans 27% 85%
A0A0S4J1G8 Bodo saltans 31% 85%
A0A0S4JBJ9 Bodo saltans 28% 90%
A0A0S4JDW3 Bodo saltans 32% 77%
A0A0S4JF89 Bodo saltans 31% 84%
A0A0S4JJX5 Bodo saltans 27% 91%
A0A0S4JKI9 Bodo saltans 29% 82%
A0A0S4JR87 Bodo saltans 30% 74%
A0A0S4JRU1 Bodo saltans 29% 89%
A0A0S4JSC1 Bodo saltans 30% 89%
A0A0S4JVK4 Bodo saltans 29% 70%
A0A0S4JYJ1 Bodo saltans 29% 81%
A0A0S4KGN8 Bodo saltans 25% 83%
A0A0S4KHE5 Bodo saltans 27% 86%
A0A0S4KLB5 Bodo saltans 60% 100%
A0A0S4KLN8 Bodo saltans 28% 78%
A0A1X0NLK7 Trypanosomatidae 30% 80%
A0A1X0NLM1 Trypanosomatidae 31% 81%
A0A1X0NLX4 Trypanosomatidae 24% 86%
A0A1X0NN96 Trypanosomatidae 31% 92%
A0A1X0NQB8 Trypanosomatidae 28% 86%
A0A1X0NR18 Trypanosomatidae 24% 85%
A0A1X0NR74 Trypanosomatidae 24% 89%
A0A1X0NRC4 Trypanosomatidae 24% 84%
A0A1X0NRE0 Trypanosomatidae 28% 87%
A0A1X0NVM5 Trypanosomatidae 28% 86%
A0A1X0NWF8 Trypanosomatidae 29% 93%
A0A1X0NYR7 Trypanosomatidae 30% 86%
A0A1X0P0N4 Trypanosomatidae 56% 100%
A0A1X0P1V3 Trypanosomatidae 29% 80%
A0A1X0P6K3 Trypanosomatidae 29% 82%
A0A1X0P706 Trypanosomatidae 26% 84%
A0A286QZ36 Stichopus japonicus 25% 97%
A0A3Q8I8T8 Leishmania donovani 22% 86%
A0A3Q8ICX9 Leishmania donovani 27% 92%
A0A3Q8ID64 Leishmania donovani 29% 88%
A0A3Q8IE68 Leishmania donovani 26% 93%
A0A3Q8IK84 Leishmania donovani 29% 86%
A0A3R7K3A9 Trypanosoma rangeli 26% 89%
A0A3R7K3N3 Trypanosoma rangeli 25% 80%
A0A3R7KA22 Trypanosoma rangeli 29% 81%
A0A3R7KBN3 Trypanosoma rangeli 28% 86%
A0A3R7KD28 Trypanosoma rangeli 30% 93%
A0A3R7L455 Trypanosoma rangeli 32% 93%
A0A3R7L7N2 Trypanosoma rangeli 60% 100%
A0A3R7LXW6 Trypanosoma rangeli 25% 83%
A0A3R7ME44 Trypanosoma rangeli 31% 77%
A0A3R7N2H4 Trypanosoma rangeli 24% 86%
A0A3R7N6U0 Trypanosoma rangeli 31% 68%
A0A3R7N9H9 Trypanosoma rangeli 29% 90%
A0A3R7N9V4 Trypanosoma rangeli 24% 85%
A0A3R7RHV7 Trypanosoma rangeli 25% 84%
A0A3R7RKC1 Trypanosoma rangeli 30% 85%
A0A3S5H4Z2 Leishmania donovani 31% 68%
A0A3S5H5Y5 Leishmania donovani 29% 83%
A0A3S5H7K4 Leishmania donovani 100% 100%
A0A3S7WRA9 Leishmania donovani 27% 89%
A0A3S7WUY8 Leishmania donovani 27% 83%
A0A3S7WV84 Leishmania donovani 23% 79%
A0A3S7X3D1 Leishmania donovani 28% 79%
A0A422MUR1 Trypanosoma rangeli 32% 84%
A0A422NH56 Trypanosoma rangeli 28% 86%
A0A422P0L6 Trypanosoma rangeli 23% 82%
A0A422P3H9 Trypanosoma rangeli 30% 81%
A1KXP5 Leishmania donovani 27% 88%
A4D1S5 Homo sapiens 31% 86%
A4FV54 Bos taurus 27% 90%
A4H506 Leishmania braziliensis 30% 100%
A4H679 Leishmania braziliensis 27% 100%
A4H6A4 Leishmania braziliensis 23% 100%
A4HEE8 Leishmania braziliensis 24% 100%
A4HFK0 Leishmania braziliensis 26% 100%
A4HH17 Leishmania braziliensis 89% 100%
A4HHR8 Leishmania braziliensis 24% 100%
A4HIB4 Leishmania braziliensis 30% 100%
A4HK33 Leishmania braziliensis 28% 100%
A4HKJ3 Leishmania braziliensis 29% 100%
A4HLP5 Leishmania braziliensis 29% 100%
A4HRM3 Leishmania infantum 31% 68%
A4HT72 Leishmania infantum 29% 100%
A4HUK3 Leishmania infantum 27% 100%
A4HUM8 Leishmania infantum 22% 100%
A4HVF7 Leishmania infantum 27% 100%
A4HXY7 Leishmania infantum 23% 100%
A4I1I6 Leishmania infantum 24% 100%
A4I5J8 Leishmania infantum 28% 79%
A4I7N3 Leishmania infantum 27% 92%
A4I825 Leishmania infantum 29% 88%
A4I946 Leishmania infantum 29% 86%
A5D7F5 Bos taurus 23% 68%
A6QR46 Bos taurus 33% 89%
A8HN58 Chlamydomonas reinhardtii 38% 91%
B1A5Z4 Leishmania donovani 24% 86%
B6DT76 Bodo saltans 27% 91%
C4YL11 Candida albicans (strain WO-1) 26% 89%
C8VQY7 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) 29% 91%
C9ZIZ1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 81%
C9ZJY0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 23% 86%
C9ZKR6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 59% 100%
C9ZQX5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 78%
C9ZUL0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 89%
C9ZVM8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 86%
C9ZVR1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 21% 85%
C9ZVS8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 87%
C9ZYS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 85%
D0A3U8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 25% 82%
D0A5C0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 23% 81%
D0A6V4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 92%
D0A9R7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 94%
D0AA67 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 79%
D0AA91 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 88%
D3Z8L7 Rattus norvegicus 28% 85%
E2RQ15 Canis lupus familiaris 29% 87%
E9ACA1 Leishmania major 31% 68%
E9AD53 Leishmania major 26% 100%
E9ADL1 Leishmania major 98% 100%
E9AGQ4 Leishmania infantum 27% 83%
E9AHE8 Leishmania infantum 26% 93%
E9AJI9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 32% 68%
E9AL68 Leishmania mexicana (strain MHOM/GT/2001/U1103) 29% 100%
E9AM70 Leishmania mexicana (strain MHOM/GT/2001/U1103) 96% 100%
E9ANA1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
E9ANC6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 23% 100%
E9AP56 Leishmania mexicana (strain MHOM/GT/2001/U1103) 25% 100%
E9ARM6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 83%
E9ARQ0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 23% 79%
E9AXM1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 24% 100%
E9AYX8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 100%
E9B0U3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 100%
E9B2H2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 29% 100%
E9B2Y3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 29% 100%
E9B420 Leishmania mexicana (strain MHOM/GT/2001/U1103) 29% 100%
F1PTE3 Canis lupus familiaris 27% 92%
G4MYS1 Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) 28% 91%
G4MZY8 Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) 33% 87%
H9BW96 Epinephelus coioides 27% 90%
I1RMF2 Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) 28% 91%
M0RC99 Rattus norvegicus 32% 87%
O00194 Homo sapiens 26% 85%
O01803 Caenorhabditis elegans 30% 88%
O04157 Arabidopsis thaliana 31% 92%
O04486 Arabidopsis thaliana 30% 86%
O13876 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 24% 79%
O14966 Homo sapiens 29% 92%
O18334 Drosophila melanogaster 33% 89%
O23561 Arabidopsis thaliana 30% 91%
O23657 Arabidopsis thaliana 30% 88%
O24466 Arabidopsis thaliana 27% 86%
O35509 Rattus norvegicus 29% 85%
O35963 Mus musculus 33% 81%
O42819 Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) 30% 87%
O42825 Candida albicans (strain SC5314 / ATCC MYA-2876) 27% 94%
O49513 Arabidopsis thaliana 28% 86%
O49841 Arabidopsis thaliana 26% 89%
O76173 Dictyostelium discoideum 28% 93%
O80501 Arabidopsis thaliana 34% 89%
O88931 Cavia porcellus 27% 97%
O94655 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 32% 91%
O95716 Homo sapiens 28% 85%
O97572 Oryctolagus cuniculus 27% 90%
P01113 Moloney murine sarcoma virus 30% 98%
P01114 Rasheed rat sarcoma virus 30% 75%
P01117 Kirsten murine sarcoma virus 29% 98%
P01123 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 30% 90%
P05712 Rattus norvegicus 26% 88%
P05714 Rattus norvegicus 30% 85%
P07560 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 30% 87%
P09527 Rattus norvegicus 27% 90%
P0C0E4 Homo sapiens 28% 67%
P0CY30 Candida albicans 26% 89%
P0CY31 Candida albicans (strain SC5314 / ATCC MYA-2876) 26% 89%
P10301 Homo sapiens 28% 85%
P10536 Rattus norvegicus 27% 93%
P10833 Mus musculus 28% 85%
P10948 Bos taurus 29% 85%
P10949 Bos taurus 26% 82%
P11023 Bos taurus 28% 85%
P11620 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 28% 92%
P15153 Homo sapiens 28% 97%
P16976 Zea mays 28% 89%
P17608 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 34% 93%
P17609 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 25% 93%
P17610 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 27% 87%
P18066 Canis lupus familiaris 32% 87%
P18067 Canis lupus familiaris 27% 90%
P19073 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 27% 97%
P19892 Arabidopsis thaliana 27% 85%
P20336 Homo sapiens 28% 85%
P20337 Homo sapiens 29% 85%
P20338 Homo sapiens 30% 85%
P20339 Homo sapiens 32% 87%
P20340 Homo sapiens 33% 89%
P20790 Dictyostelium discoideum 24% 89%
P20791 Dictyostelium discoideum 26% 92%
P22125 Diplobatis ommata 28% 92%
P22127 Diplobatis ommata 30% 93%
P22128 Diplobatis ommata 23% 89%
P22129 Diplobatis ommata 29% 85%
P23175 Murine sarcoma virus NS.C58 30% 98%
P23640 Rattus norvegicus 26% 84%
P24409 Canis lupus familiaris 30% 93%
P25228 Drosophila melanogaster 30% 85%
P25766 Oryza sativa subsp. japonica 30% 82%
P28185 Arabidopsis thaliana 29% 86%
P28186 Arabidopsis thaliana 27% 86%
P28187 Arabidopsis thaliana 27% 87%
P28188 Arabidopsis thaliana 27% 92%
P29687 Nicotiana tabacum 27% 93%
P31022 Pisum sativum 25% 90%
P31582 Arabidopsis thaliana 31% 93%
P31583 Nicotiana plumbaginifolia 30% 93%
P31584 Volvox carteri 27% 92%
P32939 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 89%
P33723 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 26% 92%
P34139 Dictyostelium discoideum 30% 92%
P34140 Dictyostelium discoideum 27% 90%
P34141 Dictyostelium discoideum 27% 93%
P34143 Dictyostelium discoideum 31% 95%
P34149 Dictyostelium discoideum 25% 97%
P34213 Caenorhabditis elegans 34% 91%
P35276 Mus musculus 28% 85%
P35278 Mus musculus 32% 86%
P35279 Mus musculus 33% 89%
P35280 Rattus norvegicus 27% 90%
P35281 Rattus norvegicus 28% 93%
P35282 Mus musculus 27% 84%
P35283 Mus musculus 32% 77%
P35284 Rattus norvegicus 32% 77%
P35285 Mus musculus 28% 96%
P35286 Rattus norvegicus 28% 92%
P35288 Mus musculus 28% 78%
P35289 Rattus norvegicus 27% 88%
P35290 Mus musculus 28% 92%
P35293 Mus musculus 29% 90%
P35294 Mus musculus 32% 86%
P36017 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 31% 89%
P36018 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 23% 79%
P36019 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 27% 85%
P36409 Dictyostelium discoideum 25% 90%
P36410 Dictyostelium discoideum 25% 90%
P36411 Dictyostelium discoideum 27% 92%
P36412 Dictyostelium discoideum 30% 87%
P36586 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 28% 88%
P36861 Volvox carteri 30% 86%
P36862 Volvox carteri 30% 92%
P36863 Volvox carteri 27% 87%
P36864 Volvox carteri 30% 91%
P38545 Plasmodium falciparum 27% 87%
P38555 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 27% 83%
P40392 Oryza sativa subsp. japonica 26% 92%
P40393 Oryza sativa subsp. japonica 30% 86%
P40792 Drosophila melanogaster 27% 97%
P41924 Yarrowia lipolytica (strain CLIB 122 / E 150) 25% 92%
P46629 Oryctolagus cuniculus 30% 87%
P46638 Mus musculus 29% 85%
P48554 Drosophila melanogaster 26% 97%
P49103 Zea mays 27% 89%
P49104 Zea mays 27% 89%
P51146 Rattus norvegicus 32% 87%
P51147 Canis lupus familiaris 32% 86%
P51148 Homo sapiens 32% 86%
P51149 Homo sapiens 27% 90%
P51150 Mus musculus 27% 90%
P51152 Canis lupus familiaris 33% 89%
P51153 Homo sapiens 27% 92%
P51154 Canis lupus familiaris 28% 96%
P51156 Rattus norvegicus 30% 72%
P51157 Homo sapiens 27% 84%
P51158 Rattus norvegicus 29% 84%
P51159 Homo sapiens 26% 84%
P51996 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 28% 84%
P53994 Mus musculus 25% 88%
P55258 Mus musculus 27% 90%
P55745 Canis lupus familiaris 27% 83%
P56371 Mus musculus 30% 85%
P57735 Homo sapiens 30% 87%
P59190 Homo sapiens 28% 88%
P59279 Mus musculus 27% 86%
P60763 Homo sapiens 29% 97%
P60764 Mus musculus 29% 97%
P61006 Homo sapiens 27% 90%
P61007 Canis lupus familiaris 27% 90%
P61017 Canis lupus familiaris 32% 87%
P61018 Homo sapiens 32% 87%
P61019 Homo sapiens 25% 88%
P61020 Homo sapiens 32% 87%
P61021 Mus musculus 32% 87%
P61026 Homo sapiens 30% 93%
P61027 Mus musculus 30% 93%
P61028 Mus musculus 24% 90%
P61105 Canis lupus familiaris 25% 88%
P61106 Homo sapiens 28% 87%
P61107 Rattus norvegicus 28% 87%
P61271 Macaca fascicularis 32% 87%
P61294 Mus musculus 33% 89%
P62490 Canis lupus familiaris 30% 86%
P62491 Homo sapiens 30% 86%
P62492 Mus musculus 30% 86%
P62493 Oryctolagus cuniculus 30% 86%
P62494 Rattus norvegicus 30% 86%
P62820 Homo sapiens 28% 91%
P62821 Mus musculus 28% 91%
P62822 Canis lupus familiaris 28% 91%
P62823 Mus musculus 26% 82%
P62824 Rattus norvegicus 26% 82%
P62827 Mus musculus 22% 86%
P62828 Rattus norvegicus 22% 86%
P62998 Bos taurus 28% 97%
P62999 Canis lupus familiaris 28% 97%
P63000 Homo sapiens 28% 97%
P63001 Mus musculus 28% 97%
P63011 Mus musculus 28% 85%
P63012 Rattus norvegicus 28% 85%
P70550 Rattus norvegicus 24% 90%
P79735 Danio rerio 22% 87%
P84095 Homo sapiens 27% 97%
P84096 Mus musculus 27% 97%
P84097 Cricetus cricetus 27% 97%
P87027 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 26% 94%
P90726 Caenorhabditis briggsae 30% 92%
P91580 Ciona intestinalis 34% 85%
P92963 Arabidopsis thaliana 27% 88%
P93267 Mesembryanthemum crystallinum 26% 90%
P97950 Mus musculus 31% 78%
Q01111 Nicotiana plumbaginifolia 28% 85%
Q01112 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 27% 97%
Q01890 Phytophthora infestans 28% 93%
Q01971 Oryctolagus cuniculus 25% 88%
Q03206 Caenorhabditis elegans 25% 97%
Q05144 Mus musculus 28% 97%
Q05737 Zea mays 27% 92%
Q05974 Lymnaea stagnalis 27% 91%
Q05975 Lymnaea stagnalis 27% 88%
Q05976 Lymnaea stagnalis 33% 92%
Q06AU3 Sus scrofa 28% 85%
Q06AU4 Sus scrofa 27% 72%
Q06AU5 Sus scrofa 28% 82%
Q06AU6 Sus scrofa 32% 87%
Q06AU7 Sus scrofa 27% 93%
Q08DE8 Bos taurus 25% 93%
Q0IIG7 Bos taurus 32% 87%
Q0IIG8 Bos taurus 29% 90%
Q0ILQ6 Oryza sativa subsp. japonica 27% 92%
Q0PD08 Mus musculus 28% 87%
Q0VCJ7 Bos taurus 28% 93%
Q0VCN3 Bos taurus 37% 100%
Q12829 Homo sapiens 27% 67%
Q13636 Homo sapiens 25% 96%
Q13637 Homo sapiens 30% 83%
Q14088 Homo sapiens 31% 78%
Q14964 Homo sapiens 28% 86%
Q15286 Homo sapiens 25% 93%
Q15771 Homo sapiens 31% 92%
Q15907 Homo sapiens 29% 85%
Q17QB7 Bos taurus 31% 92%
Q17QU4 Bos taurus 26% 87%
Q17R06 Bos taurus 27% 84%
Q1HE58 Canis lupus familiaris 25% 84%
Q1KME6 Gallus gallus 33% 89%
Q1PEX3 Arabidopsis thaliana 29% 85%
Q1RMR4 Bos taurus 29% 88%
Q22782 Caenorhabditis elegans 33% 91%
Q24192 Drosophila melanogaster 28% 98%
Q28IZ3 Xenopus tropicalis 30% 87%
Q29RR0 Bos taurus 33% 73%
Q2HJH2 Bos taurus 27% 93%
Q2HJI8 Bos taurus 24% 90%
Q2TA29 Bos taurus 30% 86%
Q2TBH7 Bos taurus 30% 85%
Q32NQ0 Xenopus laevis 29% 87%
Q35638 Pisum sativum 27% 94%
Q38919 Arabidopsis thaliana 28% 95%
Q38922 Arabidopsis thaliana 28% 88%
Q38937 Arabidopsis thaliana 28% 95%
Q39222 Arabidopsis thaliana 29% 86%
Q39433 Beta vulgaris 27% 87%
Q39434 Beta vulgaris 26% 87%
Q39570 Chlamydomonas reinhardtii 27% 87%
Q39571 Chlamydomonas reinhardtii 27% 92%
Q39572 Chlamydomonas reinhardtii 30% 86%
Q39573 Chlamydomonas reinhardtii 30% 90%
Q3MHP2 Bos taurus 29% 85%
Q3SWY9 Bos taurus 29% 84%
Q3T0F5 Bos taurus 27% 90%
Q3ZC27 Bos taurus 30% 86%
Q40191 Lotus japonicus 30% 82%
Q40193 Lotus japonicus 26% 86%
Q40194 Lotus japonicus 30% 85%
Q40195 Lotus japonicus 28% 85%
Q40520 Nicotiana tabacum 29% 84%
Q40521 Nicotiana tabacum 28% 86%
Q40522 Nicotiana tabacum 29% 84%
Q40523 Nicotiana tabacum 25% 86%
Q40723 Oryza sativa subsp. japonica 24% 86%
Q40787 Cenchrus ciliaris 28% 90%
Q41253 Gossypium hirsutum 27% 95%
Q41254 Gossypium hirsutum 27% 95%
Q41640 Vigna aconitifolia 29% 90%
Q43463 Glycine max 30% 90%
Q4LE85 Sus scrofa 25% 84%
Q4Q404 Leishmania major 29% 100%
Q4Q573 Leishmania major 29% 100%
Q4Q5N4 Leishmania major 29% 100%
Q4Q7C3 Leishmania major 28% 100%
Q4Q9V1 Leishmania major 24% 100%
Q4QDS9 Leishmania major 22% 79%
Q4QGD2 Leishmania major 27% 100%
Q4QH98 Leishmania major 22% 100%
Q4QHC3 Leishmania major 27% 100%
Q4QIN6 Leishmania major 29% 100%
Q4R4R9 Macaca fascicularis 28% 85%
Q4R4X6 Macaca fascicularis 25% 88%
Q4R5P1 Macaca fascicularis 27% 90%
Q4R8X3 Macaca fascicularis 27% 93%
Q4UB16 Theileria annulata 29% 85%
Q504M8 Mus musculus 30% 72%
Q52NJ1 Sus scrofa 30% 86%
Q52NJ2 Sus scrofa 28% 91%
Q52NJ6 Sus scrofa 28% 87%
Q53B90 Rattus norvegicus 33% 89%
Q53S08 Homo sapiens 32% 73%
Q54DA7 Dictyostelium discoideum 28% 91%
Q54FL2 Dictyostelium discoideum 26% 94%
Q54G48 Dictyostelium discoideum 29% 85%
Q54GY8 Dictyostelium discoideum 28% 92%
Q54KM9 Dictyostelium discoideum 30% 85%
Q54NU2 Dictyostelium discoideum 28% 91%
Q54P07 Dictyostelium discoideum 26% 82%
Q54QR3 Dictyostelium discoideum 28% 85%
Q54RX9 Dictyostelium discoideum 29% 87%
Q550H6 Dictyostelium discoideum 30% 83%
Q558I0 Dictyostelium discoideum 26% 98%
Q559X6 Dictyostelium discoideum 28% 92%
Q55CA9 Dictyostelium discoideum 26% 87%
Q55CB0 Dictyostelium discoideum 30% 87%
Q55CC0 Dictyostelium discoideum 27% 86%
Q55E31 Dictyostelium discoideum 29% 72%
Q55EF0 Dictyostelium discoideum 22% 85%
Q55EG6 Dictyostelium discoideum 22% 84%
Q55ET3 Dictyostelium discoideum 26% 91%
Q55FK2 Dictyostelium discoideum 33% 89%
Q580S0 Trypanosoma brucei brucei (strain 927/4 GUTat10.1) 59% 100%
Q58DS5 Bos taurus 27% 92%
Q58DS9 Bos taurus 32% 86%
Q58DW6 Bos taurus 29% 87%
Q5EB77 Rattus norvegicus 29% 90%
Q5F470 Gallus gallus 29% 90%
Q5JT25 Homo sapiens 30% 84%
Q5KTJ6 Mesocricetus auratus 26% 92%
Q5KTJ7 Mesocricetus auratus 29% 85%
Q5M7D1 Xenopus laevis 26% 67%
Q5M7U5 Rattus norvegicus 32% 86%
Q5R4A3 Pongo abelii 27% 90%
Q5R556 Pongo abelii 22% 86%
Q5R5H5 Pongo abelii 29% 90%
Q5R5U1 Pongo abelii 30% 93%
Q5R615 Pongo abelii 32% 81%
Q5R6B6 Pongo abelii 25% 88%
Q5R7A4 Pongo abelii 29% 92%
Q5R7L7 Pongo abelii 32% 86%
Q5R8Z8 Pongo abelii 28% 87%
Q5R9M7 Pongo abelii 30% 86%
Q5R9Y4 Pongo abelii 27% 90%
Q5RAV6 Pongo abelii 33% 89%
Q5RBG1 Pongo abelii 32% 87%
Q5RDE5 Pongo abelii 24% 68%
Q5RE13 Pongo abelii 27% 93%
Q5REC9 Pongo abelii 24% 90%
Q5RFI2 Pongo abelii 27% 84%
Q5U1Y1 Rattus norvegicus 27% 72%
Q5U316 Rattus norvegicus 25% 93%
Q5ZHV1 Gallus gallus 32% 82%
Q5ZHW4 Gallus gallus 32% 87%
Q5ZIT5 Gallus gallus 29% 93%
Q5ZJN2 Gallus gallus 30% 86%
Q5ZKU5 Gallus gallus 28% 87%
Q5ZLG1 Gallus gallus 29% 90%
Q63481 Rattus norvegicus 29% 91%
Q63941 Rattus norvegicus 29% 85%
Q63942 Rattus norvegicus 28% 85%
Q64008 Mus musculus 27% 72%
Q68EK7 Danio rerio 31% 87%
Q6AXT5 Rattus norvegicus 27% 83%
Q6DGL2 Danio rerio 26% 97%
Q6DHC1 Danio rerio 32% 91%
Q6DUB4 Paramecium octaurelia 25% 90%
Q6GQP4 Rattus norvegicus 25% 96%
Q6IMK3 Danio rerio 27% 68%
Q6IML7 Rattus norvegicus 25% 68%
Q6IMM1 Gallus gallus 27% 68%
Q6IQ22 Homo sapiens 33% 76%
Q6NYB7 Rattus norvegicus 28% 91%
Q6PHI9 Danio rerio 30% 87%
Q6PHN9 Mus musculus 25% 93%
Q6RUV5 Rattus norvegicus 28% 97%
Q6ZHA3 Oryza sativa subsp. japonica 30% 94%
Q76NM7 Plasmodium falciparum (isolate 3D7) 23% 90%
Q7T3A4 Danio rerio 27% 93%
Q7ZYF1 Xenopus laevis 27% 68%
Q7ZZX9 Carassius auratus 23% 87%
Q86JC8 Dictyostelium discoideum 25% 94%
Q86JP3 Dictyostelium discoideum 30% 93%
Q86YS6 Homo sapiens 30% 88%
Q8BHC1 Mus musculus 26% 87%
Q8BHD0 Mus musculus 28% 86%
Q8CFP6 Mus musculus 25% 68%
Q8CG50 Mus musculus 33% 89%
Q8HZJ5 Bos taurus 27% 85%
Q8K386 Mus musculus 28% 88%
Q8MXQ2 Dictyostelium discoideum 28% 83%
Q8MXS1 Caenorhabditis elegans 30% 92%
Q8MYF2 Dictyostelium discoideum 27% 73%
Q8R367 Mus musculus 29% 93%
Q8T6H9 Leishmania braziliensis 27% 83%
Q8VEA8 Mus musculus 27% 93%
Q8VHP8 Mus musculus 27% 67%
Q8VHQ4 Mus musculus 28% 66%
Q8WQ53 Geodia cydonium 26% 81%
Q8WUD1 Homo sapiens 27% 86%
Q8WXH6 Homo sapiens 28% 67%
Q90965 Gallus gallus 25% 88%
Q91V41 Mus musculus 28% 87%
Q91YQ1 Mus musculus 29% 91%
Q91ZR1 Mus musculus 32% 87%
Q921E2 Mus musculus 25% 96%
Q923S9 Mus musculus 31% 92%
Q92928 Homo sapiens 28% 93%
Q92930 Homo sapiens 24% 90%
Q94148 Caenorhabditis elegans 26% 93%
Q948K8 Arabidopsis thaliana 29% 90%
Q94986 Caenorhabditis elegans 28% 85%
Q95UJ0 Paramecium octaurelia 26% 90%
Q96283 Arabidopsis thaliana 26% 86%
Q969Q5 Homo sapiens 28% 92%
Q96A58 Homo sapiens 28% 93%
Q96AH8 Homo sapiens 29% 93%
Q96AX2 Homo sapiens 30% 83%
Q96DA2 Homo sapiens 26% 87%
Q96E17 Homo sapiens 26% 82%
Q96S21 Homo sapiens 28% 66%
Q98932 Gallus gallus 32% 86%
Q99260 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 30% 87%
Q99KL7 Mus musculus 29% 84%
Q99P58 Mus musculus 26% 85%
Q99P74 Rattus norvegicus 26% 85%
Q9BW83 Homo sapiens 35% 100%
Q9BZG1 Homo sapiens 27% 72%
Q9C2L8 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 28% 91%
Q9CB01 Arabidopsis thaliana 28% 92%
Q9CQD1 Mus musculus 32% 87%
Q9CZE3 Mus musculus 31% 83%
Q9CZT8 Mus musculus 29% 85%
Q9D0P8 Mus musculus 39% 100%
Q9D1G1 Mus musculus 27% 93%
Q9DD03 Mus musculus 28% 92%
Q9ERI2 Mus musculus 25% 84%
Q9FE79 Arabidopsis thaliana 29% 83%
Q9FGK5 Arabidopsis thaliana 27% 84%
Q9FIF9 Arabidopsis thaliana 27% 86%
Q9FJH0 Arabidopsis thaliana 30% 86%
Q9FJN8 Arabidopsis thaliana 28% 82%
Q9FK68 Arabidopsis thaliana 30% 86%
Q9FPJ4 Arabidopsis thaliana 26% 92%
Q9GP33 Echinococcus multilocularis 30% 83%
Q9H082 Homo sapiens 32% 81%
Q9H0N0 Homo sapiens 31% 73%
Q9H0U4 Homo sapiens 27% 93%
Q9HDY0 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 28% 89%
Q9HF56 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 27% 97%
Q9JKM7 Mus musculus 28% 83%
Q9LFT9 Arabidopsis thaliana 33% 90%
Q9LH50 Arabidopsis thaliana 32% 84%
Q9LK99 Arabidopsis thaliana 30% 86%
Q9LNK1 Arabidopsis thaliana 31% 78%
Q9LNW1 Arabidopsis thaliana 28% 87%
Q9LS94 Arabidopsis thaliana 27% 90%
Q9LV79 Arabidopsis thaliana 31% 90%
Q9N2P5 Leishmania major 28% 83%
Q9NP72 Homo sapiens 29% 90%
Q9NRW1 Homo sapiens 33% 89%
Q9NZQ0 Homo sapiens 24% 68%
Q9S810 Arabidopsis thaliana 30% 85%
Q9SEH3 Arabidopsis thaliana 26% 92%
Q9SF91 Arabidopsis thaliana 27% 85%
Q9SID8 Arabidopsis thaliana 31% 90%
Q9SIP0 Arabidopsis thaliana 27% 85%
Q9SJ11 Arabidopsis thaliana 34% 88%
Q9SMQ6 Arabidopsis thaliana 29% 83%
Q9SMR4 Arabidopsis thaliana 32% 87%
Q9SN35 Arabidopsis thaliana 29% 87%
Q9SN68 Arabidopsis thaliana 31% 93%
Q9SRS5 Arabidopsis thaliana 26% 86%
Q9TU25 Bos taurus 28% 97%
Q9TVU5 Theileria parva 29% 85%
Q9UL25 Homo sapiens 27% 83%
Q9UL26 Homo sapiens 28% 96%
Q9ULC3 Homo sapiens 28% 78%
Q9ULW5 Homo sapiens 32% 73%
Q9WTL2 Mus musculus 30% 87%
Q9WVB1 Rattus norvegicus 33% 89%
Q9XGU0 Arabidopsis thaliana 28% 89%
Q9XI98 Arabidopsis thaliana 27% 90%
Q9XWR6 Caenorhabditis elegans 30% 75%
Q9Z1Y0 Rattus norvegicus 27% 79%
Q9ZRE2 Arabidopsis thaliana 24% 91%
V5BBM5 Trypanosoma cruzi 27% 90%
V5BCH4 Trypanosoma cruzi 25% 80%
V5BJM4 Trypanosoma cruzi 28% 71%
V5BU30 Trypanosoma cruzi 30% 81%
V5D027 Trypanosoma cruzi 31% 85%
V5D1K6 Trypanosoma cruzi 29% 81%
V5D6P4 Trypanosoma cruzi 31% 68%
V5D9W7 Trypanosoma cruzi 28% 93%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS