LeishMANIAdb
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FACT complex subunit

Quick info Annotations Function or PPIs Localization Phosphorylation Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
FACT complex subunit
Gene product:
transcription factor-like protein
Species:
Leishmania infantum
UniProt:
A4I439_LEIIN
TriTrypDb:
LINF_290005100
Length:
1045

Annotations

Annotations by Jardim et al.

Transcription, Transcription factor-like

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0008023 transcription elongation factor complex 3 12
GO:0032991 protein-containing complex 1 12
GO:0035101 FACT complex 4 12
GO:0140513 nuclear protein-containing complex 2 12

Phosphorylation

Promastigote/Amastigote: 995

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

A4I439
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I439

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 12
GO:0006259 DNA metabolic process 4 12
GO:0006260 DNA replication 5 12
GO:0006281 DNA repair 5 12
GO:0006725 cellular aromatic compound metabolic process 3 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0006950 response to stress 2 12
GO:0006974 DNA damage response 4 12
GO:0008152 metabolic process 1 12
GO:0009987 cellular process 1 12
GO:0033554 cellular response to stress 3 12
GO:0034641 cellular nitrogen compound metabolic process 3 12
GO:0043170 macromolecule metabolic process 3 12
GO:0044237 cellular metabolic process 2 12
GO:0044238 primary metabolic process 2 12
GO:0044260 obsolete cellular macromolecule metabolic process 3 12
GO:0046483 heterocycle metabolic process 3 12
GO:0050896 response to stimulus 1 12
GO:0051716 cellular response to stimulus 2 12
GO:0071704 organic substance metabolic process 2 12
GO:0090304 nucleic acid metabolic process 4 12
GO:1901360 organic cyclic compound metabolic process 3 12
GO:0006325 chromatin organization 4 1
GO:0006354 DNA-templated transcription elongation 6 1
GO:0006355 regulation of DNA-templated transcription 6 1
GO:0006357 regulation of transcription by RNA polymerase II 7 1
GO:0006368 transcription elongation by RNA polymerase II 7 1
GO:0009058 biosynthetic process 2 1
GO:0009059 macromolecule biosynthetic process 4 1
GO:0009889 regulation of biosynthetic process 4 1
GO:0009891 positive regulation of biosynthetic process 5 1
GO:0009893 positive regulation of metabolic process 4 1
GO:0010468 regulation of gene expression 5 1
GO:0010556 regulation of macromolecule biosynthetic process 5 1
GO:0010557 positive regulation of macromolecule biosynthetic process 6 1
GO:0010604 positive regulation of macromolecule metabolic process 5 1
GO:0016043 cellular component organization 3 1
GO:0016070 RNA metabolic process 5 1
GO:0018130 heterocycle biosynthetic process 4 1
GO:0019219 regulation of nucleobase-containing compound metabolic process 5 1
GO:0019222 regulation of metabolic process 3 1
GO:0019438 aromatic compound biosynthetic process 4 1
GO:0031323 regulation of cellular metabolic process 4 1
GO:0031325 positive regulation of cellular metabolic process 5 1
GO:0031326 regulation of cellular biosynthetic process 5 1
GO:0031328 positive regulation of cellular biosynthetic process 6 1
GO:0032774 RNA biosynthetic process 5 1
GO:0032784 regulation of DNA-templated transcription elongation 7 1
GO:0032786 positive regulation of DNA-templated transcription, elongation 8 1
GO:0032968 positive regulation of transcription elongation by RNA polymerase II 9 1
GO:0034243 regulation of transcription elongation by RNA polymerase II 8 1
GO:0034654 nucleobase-containing compound biosynthetic process 4 1
GO:0044249 cellular biosynthetic process 3 1
GO:0044271 cellular nitrogen compound biosynthetic process 4 1
GO:0045893 positive regulation of DNA-templated transcription 7 1
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 6 1
GO:0045944 positive regulation of transcription by RNA polymerase II 8 1
GO:0048518 positive regulation of biological process 3 1
GO:0048522 positive regulation of cellular process 4 1
GO:0050789 regulation of biological process 2 1
GO:0050794 regulation of cellular process 3 1
GO:0051171 regulation of nitrogen compound metabolic process 4 1
GO:0051173 positive regulation of nitrogen compound metabolic process 5 1
GO:0051252 regulation of RNA metabolic process 5 1
GO:0051254 positive regulation of RNA metabolic process 6 1
GO:0060255 regulation of macromolecule metabolic process 4 1
GO:0065007 biological regulation 1 1
GO:0071840 cellular component organization or biogenesis 2 1
GO:0080090 regulation of primary metabolic process 4 1
GO:1901362 organic cyclic compound biosynthetic process 4 1
GO:1901576 organic substance biosynthetic process 3 1
GO:1902680 positive regulation of RNA biosynthetic process 7 1
GO:1903506 regulation of nucleic acid-templated transcription 7 1
GO:1903508 positive regulation of nucleic acid-templated transcription 8 1
GO:2001141 regulation of RNA biosynthetic process 6 1
Molecular functions
Term Name Level Count
GO:0003682 chromatin binding 2 1
GO:0005488 binding 1 1
GO:0031491 nucleosome binding 3 1
GO:0044877 protein-containing complex binding 2 1
GO:0003824 catalytic activity 1 3
GO:0004177 aminopeptidase activity 5 3
GO:0008233 peptidase activity 3 3
GO:0008238 exopeptidase activity 4 3
GO:0016787 hydrolase activity 2 3
GO:0140096 catalytic activity, acting on a protein 2 3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 932 936 PF00656 0.685
CLV_C14_Caspase3-7 946 950 PF00656 0.677
CLV_MEL_PAP_1 277 283 PF00089 0.385
CLV_NRD_NRD_1 1002 1004 PF00675 0.652
CLV_NRD_NRD_1 1043 1045 PF00675 0.624
CLV_NRD_NRD_1 190 192 PF00675 0.254
CLV_NRD_NRD_1 425 427 PF00675 0.364
CLV_NRD_NRD_1 450 452 PF00675 0.588
CLV_NRD_NRD_1 629 631 PF00675 0.228
CLV_NRD_NRD_1 725 727 PF00675 0.423
CLV_NRD_NRD_1 749 751 PF00675 0.469
CLV_NRD_NRD_1 983 985 PF00675 0.522
CLV_PCSK_KEX2_1 1004 1006 PF00082 0.691
CLV_PCSK_KEX2_1 1043 1045 PF00082 0.646
CLV_PCSK_KEX2_1 190 192 PF00082 0.255
CLV_PCSK_KEX2_1 203 205 PF00082 0.273
CLV_PCSK_KEX2_1 450 452 PF00082 0.643
CLV_PCSK_KEX2_1 631 633 PF00082 0.226
CLV_PCSK_KEX2_1 749 751 PF00082 0.586
CLV_PCSK_KEX2_1 983 985 PF00082 0.540
CLV_PCSK_PC1ET2_1 1004 1006 PF00082 0.691
CLV_PCSK_PC1ET2_1 203 205 PF00082 0.408
CLV_PCSK_PC1ET2_1 631 633 PF00082 0.298
CLV_PCSK_SKI1_1 213 217 PF00082 0.385
CLV_PCSK_SKI1_1 294 298 PF00082 0.379
CLV_PCSK_SKI1_1 388 392 PF00082 0.350
CLV_PCSK_SKI1_1 478 482 PF00082 0.373
CLV_PCSK_SKI1_1 606 610 PF00082 0.241
CLV_PCSK_SKI1_1 632 636 PF00082 0.286
CLV_PCSK_SKI1_1 727 731 PF00082 0.429
CLV_PCSK_SKI1_1 803 807 PF00082 0.383
CLV_PCSK_SKI1_1 812 816 PF00082 0.223
CLV_Separin_Metazoa 145 149 PF03568 0.476
DEG_APCC_DBOX_1 387 395 PF00400 0.265
DEG_APCC_DBOX_1 449 457 PF00400 0.583
DEG_APCC_DBOX_1 477 485 PF00400 0.484
DEG_APCC_DBOX_1 510 518 PF00400 0.433
DEG_APCC_DBOX_1 811 819 PF00400 0.437
DEG_APCC_DBOX_1 866 874 PF00400 0.437
DEG_Nend_UBRbox_3 1 3 PF02207 0.675
DEG_SCF_FBW7_1 818 825 PF00400 0.498
DEG_SCF_SKP2-CKS1_1 514 521 PF00560 0.469
DOC_CDC14_PxL_1 157 165 PF14671 0.411
DOC_CKS1_1 47 52 PF01111 0.526
DOC_CYCLIN_RxL_1 291 300 PF00134 0.385
DOC_CYCLIN_yCln2_LP_2 718 724 PF00134 0.427
DOC_MAPK_DCC_7 641 651 PF00069 0.473
DOC_MAPK_gen_1 541 548 PF00069 0.501
DOC_MAPK_gen_1 726 734 PF00069 0.348
DOC_MAPK_HePTP_8 850 862 PF00069 0.453
DOC_MAPK_MEF2A_6 1022 1030 PF00069 0.720
DOC_MAPK_MEF2A_6 541 548 PF00069 0.485
DOC_MAPK_MEF2A_6 571 578 PF00069 0.498
DOC_MAPK_MEF2A_6 726 734 PF00069 0.418
DOC_MAPK_MEF2A_6 853 862 PF00069 0.439
DOC_MAPK_RevD_3 705 720 PF00069 0.291
DOC_PP1_RVXF_1 539 546 PF00149 0.412
DOC_PP1_RVXF_1 697 704 PF00149 0.314
DOC_PP1_RVXF_1 810 817 PF00149 0.424
DOC_PP2B_LxvP_1 323 326 PF13499 0.412
DOC_PP2B_LxvP_1 649 652 PF13499 0.437
DOC_PP2B_PxIxI_1 857 863 PF00149 0.498
DOC_SPAK_OSR1_1 280 284 PF12202 0.412
DOC_USP7_MATH_1 138 142 PF00917 0.334
DOC_USP7_MATH_1 150 154 PF00917 0.407
DOC_USP7_MATH_1 228 232 PF00917 0.412
DOC_USP7_MATH_1 301 305 PF00917 0.334
DOC_USP7_MATH_1 706 710 PF00917 0.373
DOC_USP7_MATH_1 748 752 PF00917 0.561
DOC_USP7_MATH_1 866 870 PF00917 0.437
DOC_USP7_UBL2_3 203 207 PF12436 0.322
DOC_USP7_UBL2_3 423 427 PF12436 0.365
DOC_USP7_UBL2_3 594 598 PF12436 0.412
DOC_USP7_UBL2_3 853 857 PF12436 0.437
DOC_WD40_RPTOR_TOS_1 403 409 PF00400 0.265
DOC_WW_Pin1_4 1009 1014 PF00397 0.509
DOC_WW_Pin1_4 46 51 PF00397 0.421
DOC_WW_Pin1_4 515 520 PF00397 0.563
DOC_WW_Pin1_4 642 647 PF00397 0.453
DOC_WW_Pin1_4 686 691 PF00397 0.460
DOC_WW_Pin1_4 818 823 PF00397 0.491
LIG_14-3-3_CanoR_1 13 21 PF00244 0.454
LIG_14-3-3_CanoR_1 368 378 PF00244 0.350
LIG_14-3-3_CanoR_1 458 467 PF00244 0.537
LIG_14-3-3_CanoR_1 478 488 PF00244 0.187
LIG_14-3-3_CanoR_1 511 515 PF00244 0.462
LIG_14-3-3_CanoR_1 630 635 PF00244 0.423
LIG_14-3-3_CanoR_1 641 645 PF00244 0.424
LIG_14-3-3_CanoR_1 682 686 PF00244 0.465
LIG_14-3-3_CanoR_1 749 753 PF00244 0.471
LIG_14-3-3_CanoR_1 803 808 PF00244 0.464
LIG_14-3-3_CanoR_1 894 898 PF00244 0.519
LIG_Actin_WH2_2 667 684 PF00022 0.423
LIG_AP2alpha_2 907 909 PF02296 0.365
LIG_APCC_ABBA_1 270 275 PF00400 0.385
LIG_BRCT_BRCA1_1 842 846 PF00533 0.477
LIG_CaM_IQ_9 616 632 PF13499 0.473
LIG_Clathr_ClatBox_1 362 366 PF01394 0.265
LIG_CSL_BTD_1 544 547 PF09270 0.473
LIG_CtBP_PxDLS_1 1027 1031 PF00389 0.692
LIG_deltaCOP1_diTrp_1 902 909 PF00928 0.409
LIG_Dynein_DLC8_1 493 499 PF01221 0.571
LIG_EH1_1 209 217 PF00400 0.385
LIG_EH1_1 845 853 PF00400 0.498
LIG_EVH1_2 244 248 PF00568 0.385
LIG_FHA_1 100 106 PF00498 0.436
LIG_FHA_1 1010 1016 PF00498 0.571
LIG_FHA_1 115 121 PF00498 0.314
LIG_FHA_1 142 148 PF00498 0.373
LIG_FHA_1 293 299 PF00498 0.284
LIG_FHA_1 358 364 PF00498 0.291
LIG_FHA_1 374 380 PF00498 0.193
LIG_FHA_1 406 412 PF00498 0.271
LIG_FHA_1 462 468 PF00498 0.630
LIG_FHA_1 571 577 PF00498 0.409
LIG_FHA_1 6 12 PF00498 0.423
LIG_FHA_1 651 657 PF00498 0.510
LIG_FHA_1 70 76 PF00498 0.415
LIG_FHA_1 79 85 PF00498 0.397
LIG_FHA_1 823 829 PF00498 0.423
LIG_FHA_2 206 212 PF00498 0.385
LIG_FHA_2 368 374 PF00498 0.229
LIG_FHA_2 497 503 PF00498 0.493
LIG_FHA_2 687 693 PF00498 0.436
LIG_FHA_2 894 900 PF00498 0.440
LIG_FHA_2 920 926 PF00498 0.680
LIG_FHA_2 937 943 PF00498 0.467
LIG_FHA_2 94 100 PF00498 0.541
LIG_GBD_Chelix_1 424 432 PF00786 0.500
LIG_Integrin_isoDGR_2 639 641 PF01839 0.317
LIG_Integrin_RGD_1 27 29 PF01839 0.414
LIG_Integrin_RGD_1 911 913 PF01839 0.540
LIG_LIR_Apic_2 854 858 PF02991 0.437
LIG_LIR_Gen_1 141 151 PF02991 0.460
LIG_LIR_Gen_1 235 245 PF02991 0.387
LIG_LIR_Gen_1 286 296 PF02991 0.334
LIG_LIR_Gen_1 36 42 PF02991 0.362
LIG_LIR_Gen_1 430 441 PF02991 0.533
LIG_LIR_Gen_1 575 586 PF02991 0.412
LIG_LIR_Gen_1 692 703 PF02991 0.310
LIG_LIR_Gen_1 835 844 PF02991 0.479
LIG_LIR_Gen_1 913 921 PF02991 0.508
LIG_LIR_Gen_1 977 986 PF02991 0.514
LIG_LIR_LC3C_4 295 299 PF02991 0.198
LIG_LIR_Nem_3 141 146 PF02991 0.458
LIG_LIR_Nem_3 235 240 PF02991 0.387
LIG_LIR_Nem_3 286 291 PF02991 0.334
LIG_LIR_Nem_3 36 41 PF02991 0.337
LIG_LIR_Nem_3 430 436 PF02991 0.474
LIG_LIR_Nem_3 692 698 PF02991 0.320
LIG_LIR_Nem_3 709 714 PF02991 0.311
LIG_LIR_Nem_3 796 800 PF02991 0.394
LIG_LIR_Nem_3 835 839 PF02991 0.465
LIG_LIR_Nem_3 913 918 PF02991 0.458
LIG_LIR_Nem_3 977 981 PF02991 0.580
LIG_NRBOX 162 168 PF00104 0.373
LIG_NRBOX 319 325 PF00104 0.373
LIG_NRBOX 347 353 PF00104 0.334
LIG_NRBOX 476 482 PF00104 0.385
LIG_NRBOX 58 64 PF00104 0.367
LIG_Pex14_1 38 42 PF04695 0.418
LIG_Pex14_2 139 143 PF04695 0.433
LIG_PTB_Apo_2 282 289 PF02174 0.280
LIG_PTB_Phospho_1 282 288 PF10480 0.280
LIG_REV1ctd_RIR_1 289 298 PF16727 0.385
LIG_RPA_C_Fungi 22 34 PF08784 0.265
LIG_RPA_C_Fungi 8 20 PF08784 0.459
LIG_SH2_CRK 855 859 PF00017 0.299
LIG_SH2_STAP1 288 292 PF00017 0.280
LIG_SH2_STAP1 314 318 PF00017 0.334
LIG_SH2_STAP1 572 576 PF00017 0.334
LIG_SH2_STAT3 253 256 PF00017 0.280
LIG_SH2_STAT5 288 291 PF00017 0.271
LIG_SH2_STAT5 572 575 PF00017 0.308
LIG_SH2_STAT5 61 64 PF00017 0.349
LIG_SH2_STAT5 711 714 PF00017 0.417
LIG_SH3_3 1010 1016 PF00018 0.632
LIG_SH3_3 122 128 PF00018 0.474
LIG_SH3_3 44 50 PF00018 0.531
LIG_SH3_3 516 522 PF00018 0.524
LIG_SH3_3 523 529 PF00018 0.547
LIG_SH3_3 541 547 PF00018 0.234
LIG_SH3_3 88 94 PF00018 0.439
LIG_SUMO_SIM_anti_2 102 107 PF11976 0.472
LIG_SUMO_SIM_anti_2 275 280 PF11976 0.281
LIG_SUMO_SIM_anti_2 295 300 PF11976 0.081
LIG_SUMO_SIM_anti_2 346 352 PF11976 0.309
LIG_SUMO_SIM_anti_2 359 366 PF11976 0.243
LIG_SUMO_SIM_anti_2 77 84 PF11976 0.368
LIG_SUMO_SIM_anti_2 829 835 PF11976 0.299
LIG_SUMO_SIM_par_1 101 107 PF11976 0.438
LIG_SUMO_SIM_par_1 294 300 PF11976 0.299
LIG_SUMO_SIM_par_1 359 366 PF11976 0.317
LIG_SUMO_SIM_par_1 462 468 PF11976 0.626
LIG_SUMO_SIM_par_1 7 12 PF11976 0.386
LIG_SUMO_SIM_par_1 858 864 PF11976 0.385
LIG_TRAF2_1 133 136 PF00917 0.376
LIG_TRAF2_1 500 503 PF00917 0.500
LIG_TRAF2_1 580 583 PF00917 0.265
LIG_TRAF2_1 751 754 PF00917 0.431
LIG_TRAF2_1 779 782 PF00917 0.468
LIG_TRFH_1 588 592 PF08558 0.334
LIG_TYR_ITIM 431 436 PF00017 0.516
LIG_UBA3_1 58 66 PF00899 0.406
LIG_UBA3_1 694 699 PF00899 0.443
LIG_WRC_WIRS_1 773 778 PF05994 0.462
LIG_WRC_WIRS_1 833 838 PF05994 0.385
MOD_CDK_SPxK_1 515 521 PF00069 0.475
MOD_CK1_1 12 18 PF00069 0.391
MOD_CK1_1 141 147 PF00069 0.470
MOD_CK1_1 155 161 PF00069 0.410
MOD_CK1_1 238 244 PF00069 0.268
MOD_CK1_1 393 399 PF00069 0.345
MOD_CK1_1 454 460 PF00069 0.617
MOD_CK1_1 46 52 PF00069 0.500
MOD_CK1_1 633 639 PF00069 0.191
MOD_CK1_1 936 942 PF00069 0.614
MOD_CK1_1 950 956 PF00069 0.647
MOD_CK1_1 961 967 PF00069 0.580
MOD_CK1_1 970 976 PF00069 0.560
MOD_CK2_1 367 373 PF00069 0.279
MOD_CK2_1 496 502 PF00069 0.586
MOD_CK2_1 510 516 PF00069 0.465
MOD_CK2_1 748 754 PF00069 0.466
MOD_CK2_1 824 830 PF00069 0.356
MOD_CK2_1 893 899 PF00069 0.491
MOD_CK2_1 919 925 PF00069 0.635
MOD_CK2_1 93 99 PF00069 0.486
MOD_CK2_1 936 942 PF00069 0.459
MOD_CK2_1 951 957 PF00069 0.625
MOD_CK2_1 974 980 PF00069 0.618
MOD_CMANNOS 906 909 PF00535 0.390
MOD_Cter_Amidation 492 495 PF01082 0.478
MOD_GlcNHglycan 14 17 PF01048 0.320
MOD_GlcNHglycan 140 143 PF01048 0.444
MOD_GlcNHglycan 157 160 PF01048 0.331
MOD_GlcNHglycan 299 302 PF01048 0.385
MOD_GlcNHglycan 3 6 PF01048 0.477
MOD_GlcNHglycan 315 319 PF01048 0.350
MOD_GlcNHglycan 35 38 PF01048 0.382
MOD_GlcNHglycan 395 398 PF01048 0.351
MOD_GlcNHglycan 611 614 PF01048 0.400
MOD_GlcNHglycan 635 638 PF01048 0.328
MOD_GlcNHglycan 745 748 PF01048 0.605
MOD_GlcNHglycan 842 845 PF01048 0.334
MOD_GlcNHglycan 878 881 PF01048 0.385
MOD_GlcNHglycan 964 967 PF01048 0.670
MOD_GlcNHglycan 971 976 PF01048 0.604
MOD_GSK3_1 1 8 PF00069 0.538
MOD_GSK3_1 297 304 PF00069 0.366
MOD_GSK3_1 339 346 PF00069 0.259
MOD_GSK3_1 369 376 PF00069 0.352
MOD_GSK3_1 436 443 PF00069 0.562
MOD_GSK3_1 461 468 PF00069 0.644
MOD_GSK3_1 494 501 PF00069 0.526
MOD_GSK3_1 570 577 PF00069 0.276
MOD_GSK3_1 739 746 PF00069 0.486
MOD_GSK3_1 74 81 PF00069 0.364
MOD_GSK3_1 781 788 PF00069 0.423
MOD_GSK3_1 789 796 PF00069 0.455
MOD_GSK3_1 818 825 PF00069 0.353
MOD_GSK3_1 842 849 PF00069 0.348
MOD_GSK3_1 931 938 PF00069 0.635
MOD_GSK3_1 947 954 PF00069 0.552
MOD_GSK3_1 958 965 PF00069 0.543
MOD_GSK3_1 967 974 PF00069 0.623
MOD_LATS_1 801 807 PF00433 0.399
MOD_N-GLC_1 5 10 PF02516 0.483
MOD_N-GLC_1 919 924 PF02516 0.657
MOD_NEK2_1 292 297 PF00069 0.358
MOD_NEK2_1 356 361 PF00069 0.280
MOD_NEK2_1 407 412 PF00069 0.280
MOD_NEK2_1 436 441 PF00069 0.563
MOD_NEK2_1 555 560 PF00069 0.265
MOD_NEK2_1 574 579 PF00069 0.265
MOD_NEK2_1 600 605 PF00069 0.312
MOD_NEK2_1 609 614 PF00069 0.208
MOD_NEK2_1 681 686 PF00069 0.331
MOD_NEK2_1 846 851 PF00069 0.322
MOD_NEK2_1 885 890 PF00069 0.367
MOD_NEK2_2 706 711 PF00069 0.375
MOD_NEK2_2 714 719 PF00069 0.307
MOD_NEK2_2 893 898 PF00069 0.511
MOD_PIKK_1 252 258 PF00454 0.385
MOD_PIKK_1 494 500 PF00454 0.591
MOD_PIKK_1 785 791 PF00454 0.405
MOD_PIKK_1 822 828 PF00454 0.299
MOD_PKA_1 494 500 PF00069 0.519
MOD_PKA_1 630 636 PF00069 0.140
MOD_PKA_2 1021 1027 PF00069 0.691
MOD_PKA_2 114 120 PF00069 0.495
MOD_PKA_2 12 18 PF00069 0.418
MOD_PKA_2 328 334 PF00069 0.372
MOD_PKA_2 367 373 PF00069 0.234
MOD_PKA_2 510 516 PF00069 0.460
MOD_PKA_2 640 646 PF00069 0.385
MOD_PKA_2 681 687 PF00069 0.325
MOD_PKA_2 748 754 PF00069 0.468
MOD_PKA_2 766 772 PF00069 0.302
MOD_PKA_2 866 872 PF00069 0.299
MOD_PKA_2 893 899 PF00069 0.517
MOD_PKB_1 630 638 PF00069 0.322
MOD_PKB_1 990 998 PF00069 0.656
MOD_Plk_1 235 241 PF00069 0.268
MOD_Plk_1 260 266 PF00069 0.412
MOD_Plk_1 43 49 PF00069 0.517
MOD_Plk_1 5 11 PF00069 0.421
MOD_Plk_1 78 84 PF00069 0.422
MOD_Plk_1 846 852 PF00069 0.322
MOD_Plk_1 885 891 PF00069 0.348
MOD_Plk_1 936 942 PF00069 0.626
MOD_Plk_1 950 956 PF00069 0.565
MOD_Plk_2-3 205 211 PF00069 0.412
MOD_Plk_2-3 832 838 PF00069 0.280
MOD_Plk_2-3 931 937 PF00069 0.590
MOD_Plk_2-3 945 951 PF00069 0.680
MOD_Plk_2-3 99 105 PF00069 0.441
MOD_Plk_4 152 158 PF00069 0.467
MOD_Plk_4 205 211 PF00069 0.355
MOD_Plk_4 381 387 PF00069 0.299
MOD_Plk_4 407 413 PF00069 0.385
MOD_Plk_4 461 467 PF00069 0.619
MOD_Plk_4 706 712 PF00069 0.433
MOD_Plk_4 78 84 PF00069 0.399
MOD_Plk_4 803 809 PF00069 0.334
MOD_Plk_4 846 852 PF00069 0.322
MOD_Plk_4 936 942 PF00069 0.645
MOD_Plk_4 951 957 PF00069 0.485
MOD_ProDKin_1 1009 1015 PF00069 0.510
MOD_ProDKin_1 46 52 PF00069 0.414
MOD_ProDKin_1 515 521 PF00069 0.572
MOD_ProDKin_1 642 648 PF00069 0.322
MOD_ProDKin_1 686 692 PF00069 0.454
MOD_ProDKin_1 818 824 PF00069 0.375
MOD_SUMO_for_1 218 221 PF00179 0.334
MOD_SUMO_for_1 565 568 PF00179 0.241
MOD_SUMO_for_1 623 626 PF00179 0.385
MOD_SUMO_rev_2 200 209 PF00179 0.388
MOD_SUMO_rev_2 558 567 PF00179 0.257
TRG_DiLeu_BaEn_1 476 481 PF01217 0.513
TRG_DiLeu_BaEn_1 78 83 PF01217 0.353
TRG_ENDOCYTIC_2 217 220 PF00928 0.385
TRG_ENDOCYTIC_2 288 291 PF00928 0.280
TRG_ENDOCYTIC_2 433 436 PF00928 0.542
TRG_ER_diArg_1 1002 1005 PF00400 0.640
TRG_ER_diArg_1 1043 1045 PF00400 0.649
TRG_ER_diArg_1 189 191 PF00400 0.268
TRG_ER_diArg_1 449 451 PF00400 0.508
TRG_ER_diArg_1 764 767 PF00400 0.547
TRG_NES_CRM1_1 381 392 PF08389 0.276
TRG_NLS_MonoExtC_3 1002 1007 PF00514 0.637
TRG_NLS_MonoExtN_4 1002 1008 PF00514 0.621
TRG_Pf-PMV_PEXEL_1 426 430 PF00026 0.398
TRG_Pf-PMV_PEXEL_1 478 483 PF00026 0.400

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IHS5 Leptomonas seymouri 76% 99%
A0A0S4JAR0 Bodo saltans 38% 100%
A0A1X0NZD4 Trypanosomatidae 53% 100%
A0A3S7X235 Leishmania donovani 99% 100%
A0A422NUY4 Trypanosoma rangeli 54% 100%
A4HH10 Leishmania braziliensis 84% 100%
C9ZKS3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 54% 100%
E9ADK4 Leishmania major 95% 100%
E9AM77 Leishmania mexicana (strain MHOM/GT/2001/U1103) 95% 100%
O82491 Arabidopsis thaliana 26% 97%
O94267 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 24% 100%
P0CQ22 Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) 27% 100%
P0CQ23 Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) 27% 100%
P32558 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 25% 100%
Q00976 Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) 26% 100%
Q2UBF1 Aspergillus oryzae (strain ATCC 42149 / RIB 40) 25% 100%
Q4HYB8 Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) 24% 100%
Q4P2U5 Ustilago maydis (strain 521 / FGSC 9021) 26% 100%
Q4WJ02 Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) 24% 100%
Q54S43 Dictyostelium discoideum 26% 97%
Q5A1D5 Candida albicans (strain SC5314 / ATCC MYA-2876) 24% 99%
Q5B2X8 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) 24% 100%
Q61E63 Caenorhabditis briggsae 27% 100%
Q6BXE5 Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) 25% 100%
Q6C931 Yarrowia lipolytica (strain CLIB 122 / E 150) 29% 100%
Q6FWT4 Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) 25% 100%
Q756A7 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 25% 100%
Q7X923 Oryza sativa subsp. japonica 26% 99%
Q8H6B1 Zea mays 26% 99%
Q8IRG6 Drosophila melanogaster 26% 96%
Q8X0X6 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 25% 100%
Q920B9 Mus musculus 28% 100%
Q9N5R9 Caenorhabditis elegans 26% 100%
Q9W603 Xenopus laevis 27% 100%
Q9Y5B9 Homo sapiens 27% 100%
V5DLC1 Trypanosoma cruzi 52% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS