Glucosamine 6-phosphate N-acetyltransferase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

glucosamine 6-phosphate n-acetyltransferase - putative

Species:

Leishmania infantum

UniProt:

A4I436_LEIIN

TriTrypDb:

LINF_280039500

Length:

148

Annotations

Annotations by Jardim et al.

Carbohydrate metabolism, glucose 6-phosphate N-acetyltransferase

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	yes	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 16

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Show entries

Cellular components
Term	Name	Level	Count
GO:0005777	peroxisome	6	1
GO:0005783	endoplasmic reticulum	5	1
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	5	1
GO:0005794	Golgi apparatus	5	1
GO:0020015	glycosome	7	1
GO:0042579	microbody	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

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Expansion

Sequence features

A4I436

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I436

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006040	amino sugar metabolic process	4	11
GO:0006044	N-acetylglucosamine metabolic process	6	1
GO:0006047	UDP-N-acetylglucosamine metabolic process	4	11
GO:0006048	UDP-N-acetylglucosamine biosynthetic process	5	11
GO:0006139	nucleobase-containing compound metabolic process	3	11
GO:0006725	cellular aromatic compound metabolic process	3	11
GO:0006793	phosphorus metabolic process	3	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0008152	metabolic process	1	11
GO:0009058	biosynthetic process	2	11

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Show entries

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	11
GO:0004343	glucosamine 6-phosphate N-acetyltransferase activity	7	11
GO:0005488	binding	1	1
GO:0008080	N-acetyltransferase activity	6	11
GO:0016407	acetyltransferase activity	5	11
GO:0016410	N-acyltransferase activity	5	11
GO:0016740	transferase activity	2	11
GO:0016746	acyltransferase activity	3	11
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4	11
GO:0030246	carbohydrate binding	2	1

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Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	134	136	PF00675	0.441
CLV_NRD_NRD_1	42	44	PF00675	0.401
CLV_PCSK_KEX2_1	42	44	PF00082	0.400
CLV_PCSK_SKI1_1	116	120	PF00082	0.303
CLV_PCSK_SKI1_1	42	46	PF00082	0.625
CLV_PCSK_SKI1_1	99	103	PF00082	0.401
DEG_APCC_DBOX_1	41	49	PF00400	0.563
DEG_APCC_DBOX_1	98	106	PF00400	0.360
DEG_SPOP_SBC_1	53	57	PF00917	0.357
DOC_ANK_TNKS_1	92	99	PF00023	0.428

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I6H6	Leptomonas seymouri	69%	100%
A0A0S4IVM5	Bodo saltans	35%	98%
A0A1X0NQZ8	Trypanosomatidae	49%	100%
A0A3Q8IE29	Leishmania donovani	99%	100%
A0A3R7MEM9	Trypanosoma rangeli	42%	100%
A4HH04	Leishmania braziliensis	86%	100%
C7IZ16	Oryza sativa subsp. japonica	40%	89%
D0A8X2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	100%
E9B0C3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
O93806	Candida albicans	29%	99%

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