Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I414_LEIIN

TriTrypDb:

LINF_280036100

Length:

489

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I414

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I414

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	239	243	PF00656	0.664
CLV_C14_Caspase3-7	304	308	PF00656	0.583
CLV_C14_Caspase3-7	341	345	PF00656	0.584
CLV_NRD_NRD_1	126	128	PF00675	0.666
CLV_NRD_NRD_1	259	261	PF00675	0.589
CLV_NRD_NRD_1	316	318	PF00675	0.732
CLV_NRD_NRD_1	374	376	PF00675	0.525
CLV_NRD_NRD_1	477	479	PF00675	0.547
CLV_NRD_NRD_1	57	59	PF00675	0.492
CLV_PCSK_FUR_1	124	128	PF00082	0.678
CLV_PCSK_FUR_1	317	321	PF00082	0.555
CLV_PCSK_KEX2_1	126	128	PF00082	0.666
CLV_PCSK_KEX2_1	259	261	PF00082	0.589
CLV_PCSK_KEX2_1	316	318	PF00082	0.732
CLV_PCSK_KEX2_1	319	321	PF00082	0.678
CLV_PCSK_KEX2_1	374	376	PF00082	0.493
CLV_PCSK_KEX2_1	477	479	PF00082	0.490
CLV_PCSK_KEX2_1	57	59	PF00082	0.492
CLV_PCSK_PC1ET2_1	319	321	PF00082	0.556
CLV_PCSK_PC7_1	312	318	PF00082	0.730
CLV_PCSK_SKI1_1	11	15	PF00082	0.533
CLV_PCSK_SKI1_1	143	147	PF00082	0.587
CLV_PCSK_SKI1_1	219	223	PF00082	0.654
CLV_PCSK_SKI1_1	427	431	PF00082	0.540
DEG_APCC_DBOX_1	10	18	PF00400	0.525
DEG_APCC_DBOX_1	426	434	PF00400	0.580
DEG_APCC_DBOX_1	66	74	PF00400	0.502
DEG_SCF_FBW7_1	401	408	PF00400	0.619
DEG_SPOP_SBC_1	273	277	PF00917	0.748
DEG_SPOP_SBC_1	405	409	PF00917	0.635
DEG_SPOP_SBC_1	95	99	PF00917	0.703
DOC_ANK_TNKS_1	150	157	PF00023	0.790
DOC_CKS1_1	266	271	PF01111	0.638
DOC_CKS1_1	286	291	PF01111	0.668
DOC_CKS1_1	294	299	PF01111	0.565
DOC_CKS1_1	396	401	PF01111	0.609
DOC_CKS1_1	402	407	PF01111	0.539
DOC_MAPK_gen_1	374	382	PF00069	0.525
DOC_MAPK_MEF2A_6	138	146	PF00069	0.531
DOC_MAPK_MEF2A_6	375	384	PF00069	0.526
DOC_PP1_RVXF_1	141	147	PF00149	0.669
DOC_PP1_RVXF_1	217	224	PF00149	0.654
DOC_USP7_MATH_1	100	104	PF00917	0.670
DOC_USP7_MATH_1	273	277	PF00917	0.748
DOC_USP7_MATH_1	350	354	PF00917	0.781
DOC_USP7_MATH_1	411	415	PF00917	0.747
DOC_USP7_MATH_1	441	445	PF00917	0.745
DOC_WW_Pin1_4	158	163	PF00397	0.756
DOC_WW_Pin1_4	16	21	PF00397	0.672
DOC_WW_Pin1_4	262	267	PF00397	0.699
DOC_WW_Pin1_4	276	281	PF00397	0.627
DOC_WW_Pin1_4	285	290	PF00397	0.522
DOC_WW_Pin1_4	293	298	PF00397	0.573
DOC_WW_Pin1_4	395	400	PF00397	0.608
DOC_WW_Pin1_4	401	406	PF00397	0.613
LIG_14-3-3_CanoR_1	204	210	PF00244	0.505
LIG_14-3-3_CanoR_1	244	251	PF00244	0.621
LIG_14-3-3_CanoR_1	260	266	PF00244	0.549
LIG_14-3-3_CanoR_1	67	71	PF00244	0.494
LIG_APCC_ABBA_1	363	368	PF00400	0.769
LIG_BRCT_BRCA1_1	253	257	PF00533	0.671
LIG_BRCT_BRCA1_1	297	301	PF00533	0.678
LIG_FHA_1	294	300	PF00498	0.632
LIG_FHA_1	360	366	PF00498	0.781
LIG_FHA_1	396	402	PF00498	0.748
LIG_FHA_1	444	450	PF00498	0.612
LIG_FHA_1	96	102	PF00498	0.821
LIG_FHA_2	452	458	PF00498	0.728
LIG_FHA_2	481	487	PF00498	0.612
LIG_LIR_Gen_1	25	33	PF02991	0.590
LIG_LIR_Nem_3	25	31	PF02991	0.593
LIG_LIR_Nem_3	53	59	PF02991	0.651
LIG_Pex14_2	257	261	PF04695	0.749
LIG_SH2_CRK	56	60	PF00017	0.547
LIG_SH2_NCK_1	52	56	PF00017	0.538
LIG_SH2_STAP1	28	32	PF00017	0.541
LIG_SH2_STAP1	52	56	PF00017	0.538
LIG_SH2_STAT5	134	137	PF00017	0.518
LIG_SH2_STAT5	366	369	PF00017	0.748
LIG_SH2_STAT5	432	435	PF00017	0.700
LIG_SH3_1	284	290	PF00018	0.673
LIG_SH3_3	164	170	PF00018	0.767
LIG_SH3_3	263	269	PF00018	0.791
LIG_SH3_3	284	290	PF00018	0.848
LIG_SH3_3	396	402	PF00018	0.669
LIG_SH3_3	446	452	PF00018	0.668
LIG_TRAF2_1	20	23	PF00917	0.659
MOD_CDC14_SPxK_1	166	169	PF00782	0.843
MOD_CDK_SPxK_1	163	169	PF00069	0.847
MOD_CK1_1	265	271	PF00069	0.696
MOD_CK1_1	276	282	PF00069	0.738
MOD_CK1_1	353	359	PF00069	0.795
MOD_CK1_1	414	420	PF00069	0.600
MOD_CK1_1	435	441	PF00069	0.707
MOD_CK2_1	451	457	PF00069	0.705
MOD_GlcNHglycan	253	256	PF01048	0.528
MOD_GlcNHglycan	413	416	PF01048	0.657
MOD_GlcNHglycan	461	464	PF01048	0.538
MOD_GlcNHglycan	6	9	PF01048	0.542
MOD_GlcNHglycan	98	101	PF01048	0.741
MOD_GSK3_1	112	119	PF00069	0.721
MOD_GSK3_1	158	165	PF00069	0.653
MOD_GSK3_1	251	258	PF00069	0.706
MOD_GSK3_1	261	268	PF00069	0.609
MOD_GSK3_1	272	279	PF00069	0.731
MOD_GSK3_1	350	357	PF00069	0.703
MOD_GSK3_1	397	404	PF00069	0.695
MOD_GSK3_1	414	421	PF00069	0.539
MOD_GSK3_1	428	435	PF00069	0.445
MOD_GSK3_1	459	466	PF00069	0.598
MOD_GSK3_1	62	69	PF00069	0.665
MOD_GSK3_1	87	94	PF00069	0.759
MOD_GSK3_1	96	103	PF00069	0.672
MOD_N-GLC_1	180	185	PF02516	0.590
MOD_N-GLC_1	354	359	PF02516	0.638
MOD_NEK2_1	251	256	PF00069	0.549
MOD_NEK2_1	261	266	PF00069	0.635
MOD_NEK2_1	76	81	PF00069	0.578
MOD_NEK2_2	205	210	PF00069	0.527
MOD_NEK2_2	361	366	PF00069	0.789
MOD_NEK2_2	443	448	PF00069	0.641
MOD_NEK2_2	480	485	PF00069	0.555
MOD_PIKK_1	355	361	PF00454	0.634
MOD_PKA_2	243	249	PF00069	0.489
MOD_PKA_2	315	321	PF00069	0.729
MOD_PKA_2	459	465	PF00069	0.596
MOD_PKA_2	66	72	PF00069	0.496
MOD_Plk_1	306	312	PF00069	0.704
MOD_Plk_1	328	334	PF00069	0.588
MOD_Plk_1	91	97	PF00069	0.817
MOD_Plk_4	361	367	PF00069	0.703
MOD_Plk_4	428	434	PF00069	0.642
MOD_Plk_4	91	97	PF00069	0.642
MOD_ProDKin_1	158	164	PF00069	0.757
MOD_ProDKin_1	16	22	PF00069	0.671
MOD_ProDKin_1	262	268	PF00069	0.704
MOD_ProDKin_1	276	282	PF00069	0.629
MOD_ProDKin_1	285	291	PF00069	0.522
MOD_ProDKin_1	293	299	PF00069	0.568
MOD_ProDKin_1	395	401	PF00069	0.611
MOD_SUMO_for_1	26	29	PF00179	0.542
TRG_DiLeu_BaEn_1	471	476	PF01217	0.690
TRG_ENDOCYTIC_2	28	31	PF00928	0.544
TRG_ENDOCYTIC_2	56	59	PF00928	0.656
TRG_ER_diArg_1	124	127	PF00400	0.683
TRG_ER_diArg_1	168	171	PF00400	0.835
TRG_ER_diArg_1	259	261	PF00400	0.613
TRG_ER_diArg_1	373	375	PF00400	0.525
TRG_ER_diArg_1	476	478	PF00400	0.537
TRG_ER_diArg_1	49	52	PF00400	0.571
TRG_ER_diArg_1	56	58	PF00400	0.514
TRG_Pf-PMV_PEXEL_1	126	130	PF00026	0.548
TRG_Pf-PMV_PEXEL_1	195	200	PF00026	0.619
TRG_Pf-PMV_PEXEL_1	210	214	PF00026	0.425
TRG_Pf-PMV_PEXEL_1	330	334	PF00026	0.650
TRG_Pf-PMV_PEXEL_1	340	344	PF00026	0.646

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5K2	Leptomonas seymouri	37%	100%
E9B0A1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	100%