Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I3W3_LEIIN

TriTrypDb:

LINF_280030000

Length:

904

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I3W3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I3W3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	434	438	PF00656	0.689
CLV_C14_Caspase3-7	565	569	PF00656	0.653
CLV_C14_Caspase3-7	584	588	PF00656	0.582
CLV_C14_Caspase3-7	656	660	PF00656	0.703
CLV_C14_Caspase3-7	830	834	PF00656	0.593
CLV_MEL_PAP_1	449	455	PF00089	0.567
CLV_NRD_NRD_1	106	108	PF00675	0.696
CLV_NRD_NRD_1	113	115	PF00675	0.670
CLV_NRD_NRD_1	169	171	PF00675	0.643
CLV_NRD_NRD_1	338	340	PF00675	0.703
CLV_NRD_NRD_1	36	38	PF00675	0.614
CLV_NRD_NRD_1	380	382	PF00675	0.657
CLV_NRD_NRD_1	414	416	PF00675	0.839
CLV_NRD_NRD_1	420	422	PF00675	0.789
CLV_NRD_NRD_1	608	610	PF00675	0.529
CLV_NRD_NRD_1	649	651	PF00675	0.657
CLV_NRD_NRD_1	768	770	PF00675	0.696
CLV_NRD_NRD_1	79	81	PF00675	0.627
CLV_NRD_NRD_1	8	10	PF00675	0.620
CLV_PCSK_FUR_1	146	150	PF00082	0.626
CLV_PCSK_FUR_1	378	382	PF00082	0.602
CLV_PCSK_KEX2_1	106	108	PF00082	0.696
CLV_PCSK_KEX2_1	113	115	PF00082	0.670
CLV_PCSK_KEX2_1	148	150	PF00082	0.561
CLV_PCSK_KEX2_1	169	171	PF00082	0.643
CLV_PCSK_KEX2_1	338	340	PF00082	0.703
CLV_PCSK_KEX2_1	35	37	PF00082	0.621
CLV_PCSK_KEX2_1	380	382	PF00082	0.656
CLV_PCSK_KEX2_1	414	416	PF00082	0.839
CLV_PCSK_KEX2_1	420	422	PF00082	0.789
CLV_PCSK_KEX2_1	608	610	PF00082	0.529
CLV_PCSK_KEX2_1	649	651	PF00082	0.657
CLV_PCSK_KEX2_1	679	681	PF00082	0.662
CLV_PCSK_KEX2_1	79	81	PF00082	0.627
CLV_PCSK_KEX2_1	8	10	PF00082	0.624
CLV_PCSK_PC1ET2_1	148	150	PF00082	0.576
CLV_PCSK_PC1ET2_1	679	681	PF00082	0.662
CLV_PCSK_SKI1_1	114	118	PF00082	0.732
CLV_PCSK_SKI1_1	284	288	PF00082	0.513
CLV_PCSK_SKI1_1	344	348	PF00082	0.546
CLV_PCSK_SKI1_1	497	501	PF00082	0.594
CLV_PCSK_SKI1_1	734	738	PF00082	0.660
DEG_APCC_DBOX_1	283	291	PF00400	0.518
DEG_APCC_DBOX_1	351	359	PF00400	0.461
DEG_COP1_1	329	337	PF00400	0.607
DEG_SCF_FBW7_1	318	325	PF00400	0.688
DEG_SCF_TRCP1_1	529	535	PF00400	0.662
DEG_SPOP_SBC_1	322	326	PF00917	0.659
DEG_SPOP_SBC_1	40	44	PF00917	0.602
DEG_SPOP_SBC_1	665	669	PF00917	0.590
DOC_CKS1_1	164	169	PF01111	0.623
DOC_CKS1_1	183	188	PF01111	0.597
DOC_CKS1_1	319	324	PF01111	0.689
DOC_CKS1_1	819	824	PF01111	0.640
DOC_CYCLIN_yCln2_LP_2	246	249	PF00134	0.637
DOC_CYCLIN_yCln2_LP_2	557	563	PF00134	0.654
DOC_CYCLIN_yCln2_LP_2	571	577	PF00134	0.713
DOC_CYCLIN_yCln2_LP_2	838	844	PF00134	0.496
DOC_CYCLIN_yCln2_LP_2	898	904	PF00134	0.580
DOC_MAPK_MEF2A_6	724	731	PF00069	0.652
DOC_PP2B_LxvP_1	246	249	PF13499	0.637
DOC_PP2B_LxvP_1	30	33	PF13499	0.561
DOC_PP2B_LxvP_1	571	574	PF13499	0.708
DOC_PP2B_LxvP_1	717	720	PF13499	0.665
DOC_PP2B_LxvP_1	898	901	PF13499	0.580
DOC_PP4_FxxP_1	180	183	PF00568	0.625
DOC_USP7_MATH_1	10	14	PF00917	0.608
DOC_USP7_MATH_1	118	122	PF00917	0.738
DOC_USP7_MATH_1	128	132	PF00917	0.535
DOC_USP7_MATH_1	197	201	PF00917	0.674
DOC_USP7_MATH_1	322	326	PF00917	0.758
DOC_USP7_MATH_1	373	377	PF00917	0.751
DOC_USP7_MATH_1	40	44	PF00917	0.631
DOC_USP7_MATH_1	424	428	PF00917	0.682
DOC_USP7_MATH_1	477	481	PF00917	0.716
DOC_USP7_MATH_1	586	590	PF00917	0.691
DOC_USP7_MATH_1	648	652	PF00917	0.673
DOC_USP7_MATH_1	66	70	PF00917	0.619
DOC_USP7_MATH_1	665	669	PF00917	0.550
DOC_USP7_MATH_1	754	758	PF00917	0.720
DOC_USP7_MATH_1	817	821	PF00917	0.658
DOC_USP7_MATH_1	880	884	PF00917	0.625
DOC_USP7_MATH_1	885	889	PF00917	0.629
DOC_USP7_MATH_1	891	895	PF00917	0.538
DOC_WW_Pin1_4	163	168	PF00397	0.616
DOC_WW_Pin1_4	182	187	PF00397	0.639
DOC_WW_Pin1_4	192	197	PF00397	0.619
DOC_WW_Pin1_4	223	228	PF00397	0.782
DOC_WW_Pin1_4	257	262	PF00397	0.582
DOC_WW_Pin1_4	311	316	PF00397	0.804
DOC_WW_Pin1_4	318	323	PF00397	0.688
DOC_WW_Pin1_4	327	332	PF00397	0.557
DOC_WW_Pin1_4	366	371	PF00397	0.643
DOC_WW_Pin1_4	400	405	PF00397	0.784
DOC_WW_Pin1_4	420	425	PF00397	0.514
DOC_WW_Pin1_4	483	488	PF00397	0.790
DOC_WW_Pin1_4	598	603	PF00397	0.553
DOC_WW_Pin1_4	681	686	PF00397	0.666
DOC_WW_Pin1_4	706	711	PF00397	0.691
DOC_WW_Pin1_4	73	78	PF00397	0.561
DOC_WW_Pin1_4	774	779	PF00397	0.594
DOC_WW_Pin1_4	818	823	PF00397	0.666
DOC_WW_Pin1_4	837	842	PF00397	0.521
DOC_WW_Pin1_4	99	104	PF00397	0.623
LIG_14-3-3_CanoR_1	153	159	PF00244	0.673
LIG_14-3-3_CanoR_1	170	180	PF00244	0.541
LIG_14-3-3_CanoR_1	201	207	PF00244	0.680
LIG_14-3-3_CanoR_1	3	7	PF00244	0.650
LIG_14-3-3_CanoR_1	391	400	PF00244	0.600
LIG_14-3-3_CanoR_1	533	537	PF00244	0.706
LIG_14-3-3_CanoR_1	559	564	PF00244	0.821
LIG_14-3-3_CanoR_1	624	629	PF00244	0.612
LIG_14-3-3_CanoR_1	663	673	PF00244	0.609
LIG_14-3-3_CanoR_1	701	706	PF00244	0.689
LIG_14-3-3_CanoR_1	734	739	PF00244	0.802
LIG_14-3-3_CanoR_1	8	18	PF00244	0.591
LIG_BIR_II_1	1	5	PF00653	0.709
LIG_BRCT_BRCA1_1	344	348	PF00533	0.579
LIG_BRCT_BRCA1_1	855	859	PF00533	0.649
LIG_DLG_GKlike_1	624	631	PF00625	0.637
LIG_eIF4E_1	293	299	PF01652	0.567
LIG_FHA_1	239	245	PF00498	0.652
LIG_FHA_1	322	328	PF00498	0.668
LIG_FHA_1	484	490	PF00498	0.671
LIG_FHA_1	712	718	PF00498	0.673
LIG_FHA_1	754	760	PF00498	0.644
LIG_FHA_1	819	825	PF00498	0.658
LIG_FHA_2	421	427	PF00498	0.648
LIG_FHA_2	579	585	PF00498	0.663
LIG_FHA_2	652	658	PF00498	0.707
LIG_LIR_Apic_2	57	62	PF02991	0.581
LIG_LIR_Apic_2	73	77	PF02991	0.593
LIG_LIR_Gen_1	160	168	PF02991	0.582
LIG_LIR_Gen_1	345	355	PF02991	0.551
LIG_LIR_Nem_3	160	164	PF02991	0.579
LIG_LIR_Nem_3	345	351	PF02991	0.562
LIG_Pex14_1	789	793	PF04695	0.620
LIG_PTB_Apo_2	782	789	PF02174	0.503
LIG_SH2_CRK	302	306	PF00017	0.561
LIG_SH2_CRK	59	63	PF00017	0.580
LIG_SH2_CRK	74	78	PF00017	0.572
LIG_SH2_GRB2like	84	87	PF00017	0.666
LIG_SH2_NCK_1	793	797	PF00017	0.564
LIG_SH2_SRC	84	87	PF00017	0.615
LIG_SH2_STAP1	793	797	PF00017	0.538
LIG_SH2_STAT3	141	144	PF00017	0.602
LIG_SH2_STAT3	293	296	PF00017	0.557
LIG_SH2_STAT3	611	614	PF00017	0.599
LIG_SH2_STAT5	417	420	PF00017	0.658
LIG_SH2_STAT5	47	50	PF00017	0.624
LIG_SH2_STAT5	611	614	PF00017	0.548
LIG_SH3_1	106	112	PF00018	0.655
LIG_SH3_1	316	322	PF00018	0.628
LIG_SH3_2	108	113	PF14604	0.705
LIG_SH3_2	196	201	PF14604	0.647
LIG_SH3_3	105	111	PF00018	0.700
LIG_SH3_3	180	186	PF00018	0.673
LIG_SH3_3	193	199	PF00018	0.579
LIG_SH3_3	21	27	PF00018	0.623
LIG_SH3_3	242	248	PF00018	0.611
LIG_SH3_3	316	322	PF00018	0.719
LIG_SH3_3	329	335	PF00018	0.588
LIG_SH3_3	402	408	PF00018	0.681
LIG_SH3_3	450	456	PF00018	0.707
LIG_SH3_3	512	518	PF00018	0.769
LIG_SH3_3	587	593	PF00018	0.651
LIG_SH3_3	717	723	PF00018	0.746
LIG_SH3_3	775	781	PF00018	0.647
LIG_SH3_3	816	822	PF00018	0.667
LIG_SH3_CIN85_PxpxPR_1	108	113	PF14604	0.705
LIG_SH3_CIN85_PxpxPR_1	315	320	PF14604	0.669
LIG_SUMO_SIM_par_1	870	876	PF11976	0.559
LIG_TRAF2_1	552	555	PF00917	0.605
LIG_TRAF2_2	841	846	PF00917	0.614
LIG_WW_2	196	199	PF00397	0.641
LIG_WW_3	110	114	PF00397	0.716
LIG_WW_3	32	36	PF00397	0.647
MOD_CDC14_SPxK_1	330	333	PF00782	0.677
MOD_CDC14_SPxK_1	76	79	PF00782	0.543
MOD_CDK_SPK_2	311	316	PF00069	0.614
MOD_CDK_SPxK_1	163	169	PF00069	0.585
MOD_CDK_SPxK_1	327	333	PF00069	0.678
MOD_CDK_SPxK_1	73	79	PF00069	0.539
MOD_CDK_SPxxK_3	163	170	PF00069	0.655
MOD_CDK_SPxxK_3	73	80	PF00069	0.567
MOD_CDK_SPxxK_3	99	106	PF00069	0.664
MOD_CK1_1	154	160	PF00069	0.618
MOD_CK1_1	172	178	PF00069	0.795
MOD_CK1_1	2	8	PF00069	0.710
MOD_CK1_1	200	206	PF00069	0.636
MOD_CK1_1	226	232	PF00069	0.752
MOD_CK1_1	323	329	PF00069	0.660
MOD_CK1_1	369	375	PF00069	0.604
MOD_CK1_1	39	45	PF00069	0.679
MOD_CK1_1	394	400	PF00069	0.662
MOD_CK1_1	403	409	PF00069	0.664
MOD_CK1_1	478	484	PF00069	0.677
MOD_CK1_1	626	632	PF00069	0.720
MOD_CK1_1	651	657	PF00069	0.784
MOD_CK1_1	684	690	PF00069	0.794
MOD_CK1_1	70	76	PF00069	0.624
MOD_CK1_1	704	710	PF00069	0.739
MOD_CK1_1	772	778	PF00069	0.598
MOD_CK1_1	847	853	PF00069	0.682
MOD_CK2_1	559	565	PF00069	0.677
MOD_CK2_1	578	584	PF00069	0.633
MOD_CK2_1	651	657	PF00069	0.699
MOD_CK2_1	737	743	PF00069	0.727
MOD_CK2_1	891	897	PF00069	0.654
MOD_Cter_Amidation	677	680	PF01082	0.663
MOD_GlcNHglycan	12	15	PF01048	0.693
MOD_GlcNHglycan	120	123	PF01048	0.692
MOD_GlcNHglycan	130	133	PF01048	0.569
MOD_GlcNHglycan	175	178	PF01048	0.739
MOD_GlcNHglycan	180	183	PF01048	0.797
MOD_GlcNHglycan	223	226	PF01048	0.757
MOD_GlcNHglycan	335	338	PF01048	0.778
MOD_GlcNHglycan	344	347	PF01048	0.515
MOD_GlcNHglycan	38	41	PF01048	0.688
MOD_GlcNHglycan	43	46	PF01048	0.619
MOD_GlcNHglycan	434	437	PF01048	0.600
MOD_GlcNHglycan	476	480	PF01048	0.688
MOD_GlcNHglycan	529	532	PF01048	0.775
MOD_GlcNHglycan	631	634	PF01048	0.697
MOD_GlcNHglycan	646	649	PF01048	0.538
MOD_GlcNHglycan	668	671	PF01048	0.676
MOD_GlcNHglycan	676	679	PF01048	0.660
MOD_GlcNHglycan	69	72	PF01048	0.629
MOD_GlcNHglycan	691	695	PF01048	0.622
MOD_GlcNHglycan	696	699	PF01048	0.595
MOD_GlcNHglycan	703	706	PF01048	0.617
MOD_GlcNHglycan	739	742	PF01048	0.610
MOD_GlcNHglycan	756	759	PF01048	0.672
MOD_GlcNHglycan	801	804	PF01048	0.638
MOD_GlcNHglycan	814	817	PF01048	0.648
MOD_GlcNHglycan	878	881	PF01048	0.585
MOD_GlcNHglycan	882	885	PF01048	0.586
MOD_GSK3_1	114	121	PF00069	0.777
MOD_GSK3_1	169	176	PF00069	0.675
MOD_GSK3_1	178	185	PF00069	0.631
MOD_GSK3_1	197	204	PF00069	0.545
MOD_GSK3_1	318	325	PF00069	0.659
MOD_GSK3_1	36	43	PF00069	0.592
MOD_GSK3_1	369	376	PF00069	0.639
MOD_GSK3_1	420	427	PF00069	0.690
MOD_GSK3_1	478	485	PF00069	0.705
MOD_GSK3_1	644	651	PF00069	0.782
MOD_GSK3_1	66	73	PF00069	0.641
MOD_GSK3_1	686	693	PF00069	0.830
MOD_GSK3_1	700	707	PF00069	0.709
MOD_GSK3_1	730	737	PF00069	0.648
MOD_GSK3_1	749	756	PF00069	0.713
MOD_GSK3_1	849	856	PF00069	0.726
MOD_GSK3_1	876	883	PF00069	0.654
MOD_LATS_1	767	773	PF00433	0.663
MOD_N-GLC_1	128	133	PF02516	0.586
MOD_N-GLC_1	482	487	PF02516	0.582
MOD_N-GLC_1	891	896	PF02516	0.665
MOD_NEK2_1	495	500	PF00069	0.621
MOD_NEK2_1	55	60	PF00069	0.529
MOD_NEK2_1	576	581	PF00069	0.760
MOD_NEK2_1	690	695	PF00069	0.637
MOD_NEK2_1	700	705	PF00069	0.708
MOD_NEK2_1	844	849	PF00069	0.632
MOD_PIKK_1	140	146	PF00454	0.604
MOD_PIKK_1	151	157	PF00454	0.541
MOD_PIKK_1	259	265	PF00454	0.614
MOD_PIKK_1	47	53	PF00454	0.644
MOD_PIKK_1	478	484	PF00454	0.677
MOD_PKA_1	169	175	PF00069	0.644
MOD_PKA_1	36	42	PF00069	0.604
MOD_PKA_1	769	775	PF00069	0.663
MOD_PKA_2	169	175	PF00069	0.670
MOD_PKA_2	2	8	PF00069	0.710
MOD_PKA_2	200	206	PF00069	0.682
MOD_PKA_2	36	42	PF00069	0.604
MOD_PKA_2	532	538	PF00069	0.720
MOD_PKA_2	55	61	PF00069	0.529
MOD_PKA_2	623	629	PF00069	0.629
MOD_PKA_2	648	654	PF00069	0.663
MOD_PKA_2	665	671	PF00069	0.559
MOD_PKA_2	700	706	PF00069	0.689
MOD_PKB_1	622	630	PF00069	0.650
MOD_Plk_1	586	592	PF00069	0.649
MOD_Plk_1	844	850	PF00069	0.643
MOD_Plk_4	231	237	PF00069	0.771
MOD_Plk_4	239	245	PF00069	0.708
MOD_Plk_4	50	56	PF00069	0.628
MOD_Plk_4	844	850	PF00069	0.643
MOD_ProDKin_1	163	169	PF00069	0.619
MOD_ProDKin_1	182	188	PF00069	0.640
MOD_ProDKin_1	192	198	PF00069	0.619
MOD_ProDKin_1	223	229	PF00069	0.784
MOD_ProDKin_1	257	263	PF00069	0.572
MOD_ProDKin_1	311	317	PF00069	0.807
MOD_ProDKin_1	318	324	PF00069	0.688
MOD_ProDKin_1	327	333	PF00069	0.559
MOD_ProDKin_1	366	372	PF00069	0.647
MOD_ProDKin_1	400	406	PF00069	0.784
MOD_ProDKin_1	420	426	PF00069	0.515
MOD_ProDKin_1	483	489	PF00069	0.791
MOD_ProDKin_1	598	604	PF00069	0.547
MOD_ProDKin_1	681	687	PF00069	0.668
MOD_ProDKin_1	706	712	PF00069	0.691
MOD_ProDKin_1	73	79	PF00069	0.565
MOD_ProDKin_1	774	780	PF00069	0.591
MOD_ProDKin_1	818	824	PF00069	0.669
MOD_ProDKin_1	837	843	PF00069	0.523
MOD_ProDKin_1	99	105	PF00069	0.624
MOD_SUMO_rev_2	755	764	PF00179	0.590
TRG_DiLeu_BaEn_1	294	299	PF01217	0.507
TRG_DiLeu_BaEn_1	639	644	PF01217	0.707
TRG_DiLeu_BaEn_2	742	748	PF01217	0.639
TRG_DiLeu_BaLyEn_6	269	274	PF01217	0.577
TRG_DiLeu_BaLyEn_6	484	489	PF01217	0.648
TRG_DiLeu_BaLyEn_6	571	576	PF01217	0.661
TRG_DiLeu_LyEn_5	294	299	PF01217	0.489
TRG_ENDOCYTIC_2	302	305	PF00928	0.554
TRG_ENDOCYTIC_2	96	99	PF00928	0.591
TRG_ER_diArg_1	106	108	PF00400	0.699
TRG_ER_diArg_1	112	114	PF00400	0.676
TRG_ER_diArg_1	168	170	PF00400	0.664
TRG_ER_diArg_1	34	37	PF00400	0.621
TRG_ER_diArg_1	351	354	PF00400	0.520
TRG_ER_diArg_1	378	381	PF00400	0.632
TRG_ER_diArg_1	414	416	PF00400	0.841
TRG_ER_diArg_1	444	447	PF00400	0.784
TRG_ER_diArg_1	456	459	PF00400	0.662
TRG_ER_diArg_1	622	625	PF00400	0.685
TRG_ER_diArg_1	79	81	PF00400	0.635
TRG_ER_diArg_1	8	10	PF00400	0.633
TRG_Pf-PMV_PEXEL_1	272	276	PF00026	0.651

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4B6	Leptomonas seymouri	29%	100%
A0A3Q8IE27	Leishmania donovani	99%	100%
A4HGT6	Leishmania braziliensis	60%	100%
E9B053	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4Q832	Leishmania major	89%	100%