CS domain-containing protein

Quick info Annotations Localization Phosphorylation Abundance Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

Mitochondrial import receptor subunit ATOM69 - putative

Species:

Leishmania infantum

UniProt:

A4I3U6_LEIIN

TriTrypDb:

LINF_280028400

Length:

328

Annotations

Annotations by Jardim et al.

Mitochondrial protein, outer mitochondrial membrane proteome 9 (ATOM69) Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Phosphorylation

Amastigote: 129
Promastigote/Amastigote: 133, 135, 184

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4I3U6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I3U6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	222	226	PF00656	0.298
CLV_NRD_NRD_1	281	283	PF00675	0.306
CLV_PCSK_KEX2_1	281	283	PF00082	0.306
CLV_PCSK_SKI1_1	174	178	PF00082	0.399
CLV_PCSK_SKI1_1	236	240	PF00082	0.235
CLV_PCSK_SKI1_1	282	286	PF00082	0.276
CLV_PCSK_SKI1_1	39	43	PF00082	0.230
DEG_APCC_DBOX_1	120	128	PF00400	0.240
DEG_SCF_FBW7_2	109	115	PF00400	0.263
DOC_CKS1_1	109	114	PF01111	0.267
DOC_CYCLIN_yCln2_LP_2	99	105	PF00134	0.278
DOC_MAPK_gen_1	118	126	PF00069	0.245
DOC_MAPK_gen_1	281	287	PF00069	0.279
DOC_MAPK_gen_1	37	45	PF00069	0.231
DOC_MAPK_JIP1_4	37	43	PF00069	0.241
DOC_MAPK_MEF2A_6	37	45	PF00069	0.231
DOC_PP1_RVXF_1	57	64	PF00149	0.219
DOC_PP2B_LxvP_1	99	102	PF13499	0.269
DOC_USP7_MATH_1	181	185	PF00917	0.434
DOC_USP7_MATH_1	251	255	PF00917	0.208
DOC_USP7_MATH_1	67	71	PF00917	0.198
DOC_WW_Pin1_4	108	113	PF00397	0.272
LIG_14-3-3_CanoR_1	118	128	PF00244	0.242
LIG_14-3-3_CanoR_1	250	256	PF00244	0.210
LIG_14-3-3_CanoR_1	297	306	PF00244	0.370
LIG_BIR_II_1	1	5	PF00653	0.357
LIG_FHA_1	4	10	PF00498	0.320
LIG_FHA_1	40	46	PF00498	0.209
LIG_FHA_1	56	62	PF00498	0.231
LIG_FHA_2	175	181	PF00498	0.419
LIG_FHA_2	20	26	PF00498	0.235
LIG_FHA_2	222	228	PF00498	0.296
LIG_FHA_2	229	235	PF00498	0.263
LIG_FHA_2	264	270	PF00498	0.204
LIG_NRBOX	164	170	PF00104	0.344
LIG_SH2_CRK	66	70	PF00017	0.196
LIG_SH2_NCK_1	66	70	PF00017	0.196
LIG_SH3_3	122	128	PF00018	0.243
LIG_SH3_3	23	29	PF00018	0.219
LIG_UBA3_1	50	56	PF00899	0.182
MOD_CK1_1	254	260	PF00069	0.209
MOD_CK1_1	310	316	PF00069	0.341
MOD_CK2_1	130	136	PF00069	0.349
MOD_CK2_1	174	180	PF00069	0.412
MOD_CK2_1	181	187	PF00069	0.423
MOD_CK2_1	19	25	PF00069	0.255
MOD_CK2_1	228	234	PF00069	0.264
MOD_CK2_1	254	260	PF00069	0.209
MOD_CK2_1	51	57	PF00069	0.196
MOD_Cter_Amidation	279	282	PF01082	0.318
MOD_GlcNHglycan	142	145	PF01048	0.425
MOD_GlcNHglycan	278	281	PF01048	0.315
MOD_GlcNHglycan	299	302	PF01048	0.369
MOD_GlcNHglycan	90	93	PF01048	0.237
MOD_GSK3_1	126	133	PF00069	0.282
MOD_GSK3_1	216	223	PF00069	0.262
MOD_GSK3_1	226	233	PF00069	0.272
MOD_GSK3_1	251	258	PF00069	0.203
MOD_GSK3_1	51	58	PF00069	0.202
MOD_N-GLC_1	220	225	PF02516	0.287
MOD_N-GLC_2	286	288	PF02516	0.284
MOD_NEK2_1	119	124	PF00069	0.246
MOD_NEK2_1	263	268	PF00069	0.208
MOD_NEK2_1	315	320	PF00069	0.367
MOD_NEK2_1	51	56	PF00069	0.184
MOD_PIKK_1	119	125	PF00454	0.243
MOD_PIKK_1	244	250	PF00454	0.204
MOD_PIKK_1	251	257	PF00454	0.207
MOD_PIKK_1	263	269	PF00454	0.207
MOD_PK_1	46	52	PF00069	0.193
MOD_PKA_2	296	302	PF00069	0.370
MOD_PKB_1	37	45	PF00069	0.231
MOD_Plk_1	216	222	PF00069	0.261
MOD_Plk_1	39	45	PF00069	0.221
MOD_Plk_2-3	132	138	PF00069	0.368
MOD_Plk_4	310	316	PF00069	0.341
MOD_Plk_4	46	52	PF00069	0.193
MOD_ProDKin_1	108	114	PF00069	0.271
MOD_SUMO_for_1	195	198	PF00179	0.246
MOD_SUMO_rev_2	175	184	PF00179	0.426
MOD_SUMO_rev_2	233	238	PF00179	0.258
MOD_SUMO_rev_2	86	91	PF00179	0.218
TRG_ENDOCYTIC_2	66	69	PF00928	0.199
TRG_ER_diArg_1	281	283	PF00400	0.306
TRG_ER_diArg_1	36	39	PF00400	0.265
TRG_NLS_MonoExtC_3	209	215	PF00514	0.245
TRG_Pf-PMV_PEXEL_1	167	171	PF00026	0.344
TRG_Pf-PMV_PEXEL_1	211	215	PF00026	0.251
TRG_Pf-PMV_PEXEL_1	39	44	PF00026	0.228