Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DnaJ domain containing protein - putative

Species:

Leishmania infantum

UniProt:

A4I3R6_LEIIN

TriTrypDb:

LINF_280025400

Length:

578

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I3R6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I3R6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	146	150	PF00656	0.750
CLV_C14_Caspase3-7	456	460	PF00656	0.539
CLV_NRD_NRD_1	152	154	PF00675	0.754
CLV_NRD_NRD_1	228	230	PF00675	0.761
CLV_NRD_NRD_1	307	309	PF00675	0.839
CLV_NRD_NRD_1	52	54	PF00675	0.505
CLV_NRD_NRD_1	535	537	PF00675	0.810
CLV_NRD_NRD_1	83	85	PF00675	0.426
CLV_PCSK_FUR_1	304	308	PF00082	0.837
CLV_PCSK_FUR_1	533	537	PF00082	0.724
CLV_PCSK_KEX2_1	152	154	PF00082	0.743
CLV_PCSK_KEX2_1	228	230	PF00082	0.761
CLV_PCSK_KEX2_1	306	308	PF00082	0.838
CLV_PCSK_KEX2_1	52	54	PF00082	0.634
CLV_PCSK_KEX2_1	535	537	PF00082	0.810
CLV_PCSK_KEX2_1	82	84	PF00082	0.426
CLV_PCSK_SKI1_1	239	243	PF00082	0.663
CLV_PCSK_SKI1_1	572	576	PF00082	0.659
DEG_COP1_1	243	250	PF00400	0.572
DEG_Nend_UBRbox_3	1	3	PF02207	0.703
DEG_SPOP_SBC_1	166	170	PF00917	0.629
DEG_SPOP_SBC_1	334	338	PF00917	0.586
DEG_SPOP_SBC_1	486	490	PF00917	0.787
DOC_CDC14_PxL_1	324	332	PF14671	0.791
DOC_CYCLIN_yClb3_PxF_3	185	191	PF00134	0.817
DOC_CYCLIN_yCln2_LP_2	183	189	PF00134	0.735
DOC_MAPK_gen_1	120	130	PF00069	0.533
DOC_MAPK_gen_1	82	92	PF00069	0.426
DOC_MAPK_MEF2A_6	83	92	PF00069	0.426
DOC_PP2B_LxvP_1	183	186	PF13499	0.732
DOC_PP4_FxxP_1	426	429	PF00568	0.715
DOC_USP7_MATH_1	140	144	PF00917	0.723
DOC_USP7_MATH_1	334	338	PF00917	0.635
DOC_USP7_MATH_1	440	444	PF00917	0.659
DOC_USP7_MATH_1	528	532	PF00917	0.765
DOC_WW_Pin1_4	176	181	PF00397	0.818
DOC_WW_Pin1_4	185	190	PF00397	0.651
DOC_WW_Pin1_4	216	221	PF00397	0.770
DOC_WW_Pin1_4	232	237	PF00397	0.616
DOC_WW_Pin1_4	335	340	PF00397	0.784
DOC_WW_Pin1_4	487	492	PF00397	0.763
DOC_WW_Pin1_4	514	519	PF00397	0.644
LIG_14-3-3_CanoR_1	101	109	PF00244	0.405
LIG_14-3-3_CanoR_1	239	248	PF00244	0.599
LIG_14-3-3_CanoR_1	414	420	PF00244	0.698
LIG_14-3-3_CanoR_1	432	440	PF00244	0.707
LIG_14-3-3_CanoR_1	446	455	PF00244	0.605
LIG_14-3-3_CanoR_1	465	475	PF00244	0.695
LIG_APCC_ABBA_1	90	95	PF00400	0.529
LIG_BIR_III_2	288	292	PF00653	0.743
LIG_BRCT_BRCA1_1	102	106	PF00533	0.529
LIG_BRCT_BRCA1_1	187	191	PF00533	0.781
LIG_BRCT_BRCA1_1	523	527	PF00533	0.580
LIG_EVH1_2	250	254	PF00568	0.798
LIG_EVH1_2	283	287	PF00568	0.800
LIG_EVH1_2	328	332	PF00568	0.794
LIG_FHA_1	397	403	PF00498	0.652
LIG_FHA_1	419	425	PF00498	0.768
LIG_FHA_2	29	35	PF00498	0.625
LIG_FHA_2	318	324	PF00498	0.608
LIG_FHA_2	336	342	PF00498	0.687
LIG_FHA_2	371	377	PF00498	0.699
LIG_Integrin_RGD_1	153	155	PF01839	0.705
LIG_LIR_Gen_1	103	113	PF02991	0.529
LIG_LIR_Gen_1	495	505	PF02991	0.539
LIG_LIR_Nem_3	103	109	PF02991	0.529
LIG_LIR_Nem_3	111	116	PF02991	0.397
LIG_LIR_Nem_3	495	501	PF02991	0.559
LIG_MYND_1	185	189	PF01753	0.815
LIG_NRBOX	373	379	PF00104	0.702
LIG_SH2_CRK	498	502	PF00017	0.657
LIG_SH2_CRK	85	89	PF00017	0.529
LIG_SH2_NCK_1	419	423	PF00017	0.588
LIG_SH2_STAP1	419	423	PF00017	0.588
LIG_SH2_STAT5	115	118	PF00017	0.480
LIG_SH2_STAT5	165	168	PF00017	0.727
LIG_SH3_1	201	207	PF00018	0.744
LIG_SH3_1	217	223	PF00018	0.636
LIG_SH3_1	53	59	PF00018	0.619
LIG_SH3_2	142	147	PF14604	0.601
LIG_SH3_2	223	228	PF14604	0.730
LIG_SH3_3	139	145	PF00018	0.704
LIG_SH3_3	179	185	PF00018	0.819
LIG_SH3_3	201	207	PF00018	0.659
LIG_SH3_3	217	223	PF00018	0.636
LIG_SH3_3	244	250	PF00018	0.778
LIG_SH3_3	263	269	PF00018	0.527
LIG_SH3_3	276	282	PF00018	0.655
LIG_SH3_3	323	329	PF00018	0.709
LIG_SH3_3	366	372	PF00018	0.781
LIG_SH3_3	53	59	PF00018	0.619
LIG_SUMO_SIM_anti_2	37	43	PF11976	0.537
LIG_TRAF2_1	31	34	PF00917	0.542
LIG_TRAF2_1	500	503	PF00917	0.654
LIG_WW_3	219	223	PF00397	0.818
MOD_CDC14_SPxK_1	219	222	PF00782	0.755
MOD_CDK_SPxK_1	216	222	PF00069	0.768
MOD_CDK_SPxxK_3	232	239	PF00069	0.614
MOD_CK1_1	100	106	PF00069	0.529
MOD_CK1_1	164	170	PF00069	0.730
MOD_CK1_1	171	177	PF00069	0.695
MOD_CK1_1	181	187	PF00069	0.632
MOD_CK1_1	192	198	PF00069	0.588
MOD_CK1_1	199	205	PF00069	0.567
MOD_CK1_1	257	263	PF00069	0.610
MOD_CK1_1	337	343	PF00069	0.779
MOD_CK1_1	392	398	PF00069	0.690
MOD_CK1_1	4	10	PF00069	0.647
MOD_CK1_1	408	414	PF00069	0.554
MOD_CK1_1	447	453	PF00069	0.632
MOD_CK1_1	478	484	PF00069	0.787
MOD_CK1_1	485	491	PF00069	0.719
MOD_CK1_1	514	520	PF00069	0.754
MOD_CK1_1	531	537	PF00069	0.804
MOD_CK1_1	546	552	PF00069	0.596
MOD_CK1_1	74	80	PF00069	0.529
MOD_CK2_1	108	114	PF00069	0.465
MOD_CK2_1	115	121	PF00069	0.369
MOD_CK2_1	140	146	PF00069	0.801
MOD_CK2_1	28	34	PF00069	0.648
MOD_CK2_1	370	376	PF00069	0.712
MOD_CK2_1	489	495	PF00069	0.688
MOD_GlcNHglycan	125	128	PF01048	0.626
MOD_GlcNHglycan	14	17	PF01048	0.764
MOD_GlcNHglycan	176	179	PF01048	0.656
MOD_GlcNHglycan	198	201	PF01048	0.688
MOD_GlcNHglycan	20	23	PF01048	0.569
MOD_GlcNHglycan	243	246	PF01048	0.750
MOD_GlcNHglycan	256	259	PF01048	0.601
MOD_GlcNHglycan	341	345	PF01048	0.751
MOD_GlcNHglycan	364	367	PF01048	0.714
MOD_GlcNHglycan	410	413	PF01048	0.815
MOD_GlcNHglycan	426	429	PF01048	0.658
MOD_GlcNHglycan	45	49	PF01048	0.621
MOD_GlcNHglycan	451	454	PF01048	0.661
MOD_GlcNHglycan	484	487	PF01048	0.734
MOD_GlcNHglycan	498	501	PF01048	0.473
MOD_GlcNHglycan	514	517	PF01048	0.720
MOD_GlcNHglycan	545	548	PF01048	0.828
MOD_GlcNHglycan	554	557	PF01048	0.661
MOD_GlcNHglycan	76	79	PF01048	0.516
MOD_GSK3_1	1	8	PF00069	0.794
MOD_GSK3_1	12	19	PF00069	0.579
MOD_GSK3_1	136	143	PF00069	0.737
MOD_GSK3_1	161	168	PF00069	0.651
MOD_GSK3_1	169	176	PF00069	0.655
MOD_GSK3_1	181	188	PF00069	0.766
MOD_GSK3_1	189	196	PF00069	0.609
MOD_GSK3_1	202	209	PF00069	0.599
MOD_GSK3_1	253	260	PF00069	0.744
MOD_GSK3_1	308	315	PF00069	0.826
MOD_GSK3_1	333	340	PF00069	0.687
MOD_GSK3_1	392	399	PF00069	0.715
MOD_GSK3_1	401	408	PF00069	0.617
MOD_GSK3_1	440	447	PF00069	0.777
MOD_GSK3_1	475	482	PF00069	0.764
MOD_GSK3_1	485	492	PF00069	0.681
MOD_GSK3_1	510	517	PF00069	0.727
MOD_GSK3_1	527	534	PF00069	0.800
MOD_GSK3_1	542	549	PF00069	0.591
MOD_GSK3_1	552	559	PF00069	0.679
MOD_GSK3_1	96	103	PF00069	0.373
MOD_LATS_1	444	450	PF00433	0.708
MOD_N-GLC_1	405	410	PF02516	0.714
MOD_N-GLC_1	424	429	PF02516	0.511
MOD_N-GLC_1	447	452	PF02516	0.751
MOD_N-GLC_1	96	101	PF02516	0.446
MOD_NEK2_1	108	113	PF00069	0.446
MOD_NEK2_1	17	22	PF00069	0.528
MOD_NEK2_1	254	259	PF00069	0.614
MOD_NEK2_1	272	277	PF00069	0.798
MOD_NEK2_1	317	322	PF00069	0.595
MOD_NEK2_1	433	438	PF00069	0.736
MOD_NEK2_1	475	480	PF00069	0.722
MOD_NEK2_1	527	532	PF00069	0.803
MOD_NEK2_2	528	533	PF00069	0.716
MOD_PKA_1	307	313	PF00069	0.744
MOD_PKA_2	100	106	PF00069	0.405
MOD_PKA_2	307	313	PF00069	0.806
MOD_PKA_2	464	470	PF00069	0.705
MOD_PKA_2	547	553	PF00069	0.724
MOD_PKB_1	306	314	PF00069	0.828
MOD_Plk_1	392	398	PF00069	0.613
MOD_Plk_2-3	370	376	PF00069	0.712
MOD_Plk_4	161	167	PF00069	0.633
MOD_ProDKin_1	176	182	PF00069	0.818
MOD_ProDKin_1	185	191	PF00069	0.653
MOD_ProDKin_1	216	222	PF00069	0.768
MOD_ProDKin_1	232	238	PF00069	0.613
MOD_ProDKin_1	335	341	PF00069	0.784
MOD_ProDKin_1	487	493	PF00069	0.758
MOD_ProDKin_1	514	520	PF00069	0.644
MOD_SUMO_rev_2	155	164	PF00179	0.639
MOD_SUMO_rev_2	499	508	PF00179	0.524
TRG_DiLeu_BaEn_1	104	109	PF01217	0.344
TRG_DiLeu_BaEn_1	37	42	PF01217	0.539
TRG_ENDOCYTIC_2	498	501	PF00928	0.655
TRG_ENDOCYTIC_2	85	88	PF00928	0.369
TRG_ER_diArg_1	151	153	PF00400	0.768
TRG_ER_diArg_1	228	230	PF00400	0.719
TRG_ER_diArg_1	303	306	PF00400	0.824
TRG_ER_diArg_1	532	535	PF00400	0.717
TRG_ER_diArg_1	569	572	PF00400	0.581
TRG_ER_diArg_1	81	84	PF00400	0.418

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IB27	Leishmania donovani	99%	100%
A4HGP3	Leishmania braziliensis	60%	100%
E9B009	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%
Q4Q876	Leishmania major	82%	100%