AN1-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

AN1-like Zinc finger containing protein - putative

Species:

Leishmania infantum

UniProt:

A4I3J6_LEIIN

TriTrypDb:

LINF_280017500

Length:

118

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I3J6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I3J6

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	8
GO:0008270	zinc ion binding	6	8
GO:0043167	ion binding	2	8
GO:0043169	cation binding	3	8
GO:0046872	metal ion binding	4	8
GO:0046914	transition metal ion binding	5	8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	60	62	PF00675	0.488
CLV_NRD_NRD_1	63	65	PF00675	0.502
CLV_NRD_NRD_1	86	88	PF00675	0.536
CLV_PCSK_FUR_1	61	65	PF00082	0.577
CLV_PCSK_KEX2_1	60	62	PF00082	0.512
CLV_PCSK_KEX2_1	63	65	PF00082	0.530
CLV_PCSK_KEX2_1	73	75	PF00082	0.444
CLV_PCSK_KEX2_1	86	88	PF00082	0.569
CLV_PCSK_PC1ET2_1	73	75	PF00082	0.543
CLV_PCSK_SKI1_1	50	54	PF00082	0.452
DOC_USP7_UBL2_3	73	77	PF12436	0.507
LIG_14-3-3_CanoR_1	27	35	PF00244	0.329
LIG_BIR_II_1	1	5	PF00653	0.542
LIG_FHA_2	101	107	PF00498	0.481
LIG_SH2_STAP1	112	116	PF00017	0.373
LIG_SH2_STAT5	28	31	PF00017	0.453
LIG_SH3_3	13	19	PF00018	0.409
MOD_CK2_1	100	106	PF00069	0.498
MOD_GlcNHglycan	103	106	PF01048	0.408
MOD_PKA_1	87	93	PF00069	0.581
MOD_SUMO_for_1	19	22	PF00179	0.409
MOD_SUMO_rev_2	70	79	PF00179	0.549
TRG_ER_diArg_1	60	63	PF00400	0.565
TRG_NLS_Bipartite_1	72	92	PF00514	0.564
TRG_NLS_MonoExtC_3	86	91	PF00514	0.603
TRG_NLS_MonoExtN_4	86	92	PF00514	0.611
TRG_Pf-PMV_PEXEL_1	64	69	PF00026	0.619

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCY9	Leptomonas seymouri	80%	100%
A0A1X0NYL9	Trypanosomatidae	62%	81%
A0A3Q8IGQ3	Leishmania donovani	100%	100%
A4HGG4	Leishmania braziliensis	88%	100%
E9AZT6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
Q4Q8E9	Leishmania major	95%	100%