LeishMANIAdb
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Ribonucleoside-diphosphate reductase

Quick info Annotations Function or PPIs Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Ribonucleoside-diphosphate reductase
Gene product:
ribonucleoside-diphosphate reductase large chain - putative
Species:
Leishmania infantum
UniProt:
A4I3G6_LEIIN
TriTrypDb:
LINF_280014500
Length:
799

Annotations

Annotations by Jardim et al.

Pyrimidine metabolism, Ribonucleoside-diphosphate reductase

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) yes yes: 3
Silverman et al. no yes: 0
Pissara et al. yes yes: 20
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005971 ribonucleoside-diphosphate reductase complex 4 1
GO:0032991 protein-containing complex 1 1
GO:1902494 catalytic complex 2 1
GO:1990204 oxidoreductase complex 3 1

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

A4I3G6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I3G6

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 12
GO:0006259 DNA metabolic process 4 12
GO:0006260 DNA replication 5 12
GO:0006725 cellular aromatic compound metabolic process 3 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009987 cellular process 1 12
GO:0034641 cellular nitrogen compound metabolic process 3 12
GO:0043170 macromolecule metabolic process 3 12
GO:0044237 cellular metabolic process 2 12
GO:0044238 primary metabolic process 2 12
GO:0044260 obsolete cellular macromolecule metabolic process 3 12
GO:0046483 heterocycle metabolic process 3 12
GO:0071704 organic substance metabolic process 2 12
GO:0090304 nucleic acid metabolic process 4 12
GO:1901360 organic cyclic compound metabolic process 3 12
GO:0006753 nucleoside phosphate metabolic process 4 1
GO:0006793 phosphorus metabolic process 3 1
GO:0006796 phosphate-containing compound metabolic process 4 1
GO:0009058 biosynthetic process 2 1
GO:0009117 nucleotide metabolic process 5 1
GO:0009165 nucleotide biosynthetic process 6 1
GO:0009262 deoxyribonucleotide metabolic process 4 1
GO:0009263 deoxyribonucleotide biosynthetic process 5 1
GO:0018130 heterocycle biosynthetic process 4 1
GO:0019438 aromatic compound biosynthetic process 4 1
GO:0019637 organophosphate metabolic process 3 1
GO:0034654 nucleobase-containing compound biosynthetic process 4 1
GO:0044249 cellular biosynthetic process 3 1
GO:0044271 cellular nitrogen compound biosynthetic process 4 1
GO:0044281 small molecule metabolic process 2 1
GO:0055086 nucleobase-containing small molecule metabolic process 3 1
GO:0090407 organophosphate biosynthetic process 4 1
GO:1901135 carbohydrate derivative metabolic process 3 1
GO:1901137 carbohydrate derivative biosynthetic process 4 1
GO:1901293 nucleoside phosphate biosynthetic process 5 1
GO:1901362 organic cyclic compound biosynthetic process 4 1
GO:1901576 organic substance biosynthetic process 3 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 12
GO:0003824 catalytic activity 1 12
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor 6 12
GO:0005488 binding 1 12
GO:0005524 ATP binding 5 12
GO:0016491 oxidoreductase activity 2 12
GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 3 12
GO:0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor 4 12
GO:0017076 purine nucleotide binding 4 12
GO:0030554 adenyl nucleotide binding 5 12
GO:0032553 ribonucleotide binding 3 12
GO:0032555 purine ribonucleotide binding 4 12
GO:0032559 adenyl ribonucleotide binding 5 12
GO:0035639 purine ribonucleoside triphosphate binding 4 12
GO:0036094 small molecule binding 2 12
GO:0043167 ion binding 2 12
GO:0043168 anion binding 3 12
GO:0061731 ribonucleoside-diphosphate reductase activity 5 12
GO:0097159 organic cyclic compound binding 2 12
GO:0097367 carbohydrate derivative binding 2 12
GO:1901265 nucleoside phosphate binding 3 12
GO:1901363 heterocyclic compound binding 2 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 236 240 PF00656 0.328
CLV_NRD_NRD_1 25 27 PF00675 0.310
CLV_NRD_NRD_1 302 304 PF00675 0.234
CLV_NRD_NRD_1 350 352 PF00675 0.255
CLV_NRD_NRD_1 503 505 PF00675 0.282
CLV_NRD_NRD_1 640 642 PF00675 0.234
CLV_NRD_NRD_1 701 703 PF00675 0.379
CLV_PCSK_KEX2_1 10 12 PF00082 0.220
CLV_PCSK_KEX2_1 24 26 PF00082 0.284
CLV_PCSK_KEX2_1 302 304 PF00082 0.234
CLV_PCSK_KEX2_1 325 327 PF00082 0.328
CLV_PCSK_KEX2_1 350 352 PF00082 0.299
CLV_PCSK_KEX2_1 469 471 PF00082 0.379
CLV_PCSK_KEX2_1 503 505 PF00082 0.282
CLV_PCSK_KEX2_1 640 642 PF00082 0.234
CLV_PCSK_KEX2_1 768 770 PF00082 0.569
CLV_PCSK_PC1ET2_1 10 12 PF00082 0.210
CLV_PCSK_PC1ET2_1 302 304 PF00082 0.234
CLV_PCSK_PC1ET2_1 325 327 PF00082 0.328
CLV_PCSK_PC1ET2_1 469 471 PF00082 0.379
CLV_PCSK_PC1ET2_1 768 770 PF00082 0.569
CLV_PCSK_SKI1_1 183 187 PF00082 0.234
CLV_PCSK_SKI1_1 205 209 PF00082 0.380
CLV_PCSK_SKI1_1 304 308 PF00082 0.234
CLV_PCSK_SKI1_1 336 340 PF00082 0.234
CLV_PCSK_SKI1_1 350 354 PF00082 0.234
CLV_PCSK_SKI1_1 389 393 PF00082 0.303
CLV_PCSK_SKI1_1 482 486 PF00082 0.276
CLV_PCSK_SKI1_1 50 54 PF00082 0.269
CLV_PCSK_SKI1_1 640 644 PF00082 0.234
CLV_PCSK_SKI1_1 768 772 PF00082 0.497
DEG_APCC_DBOX_1 157 165 PF00400 0.234
DOC_ANK_TNKS_1 507 514 PF00023 0.254
DOC_MAPK_gen_1 302 311 PF00069 0.234
DOC_MAPK_gen_1 508 516 PF00069 0.268
DOC_MAPK_HePTP_8 250 262 PF00069 0.249
DOC_MAPK_JIP1_4 510 516 PF00069 0.328
DOC_MAPK_MEF2A_6 253 262 PF00069 0.234
DOC_MAPK_MEF2A_6 36 43 PF00069 0.490
DOC_MAPK_MEF2A_6 508 516 PF00069 0.268
DOC_MAPK_MEF2A_6 598 606 PF00069 0.379
DOC_PP1_RVXF_1 142 149 PF00149 0.433
DOC_PP2B_LxvP_1 342 345 PF13499 0.234
DOC_PP2B_LxvP_1 611 614 PF13499 0.213
DOC_USP7_MATH_1 223 227 PF00917 0.288
DOC_USP7_MATH_1 267 271 PF00917 0.328
DOC_USP7_MATH_1 420 424 PF00917 0.299
DOC_USP7_MATH_1 502 506 PF00917 0.268
DOC_USP7_MATH_1 529 533 PF00917 0.328
DOC_USP7_MATH_1 550 554 PF00917 0.299
DOC_USP7_MATH_1 616 620 PF00917 0.234
DOC_USP7_MATH_1 632 636 PF00917 0.234
DOC_USP7_UBL2_3 353 357 PF12436 0.274
DOC_USP7_UBL2_3 424 428 PF12436 0.234
DOC_WW_Pin1_4 209 214 PF00397 0.234
DOC_WW_Pin1_4 217 222 PF00397 0.234
DOC_WW_Pin1_4 444 449 PF00397 0.298
DOC_WW_Pin1_4 567 572 PF00397 0.234
DOC_WW_Pin1_4 724 729 PF00397 0.328
LIG_14-3-3_CanoR_1 350 360 PF00244 0.381
LIG_14-3-3_CanoR_1 50 58 PF00244 0.503
LIG_14-3-3_CanoR_1 607 611 PF00244 0.234
LIG_14-3-3_CanoR_1 787 791 PF00244 0.585
LIG_Actin_WH2_2 179 196 PF00022 0.255
LIG_Actin_WH2_2 730 748 PF00022 0.401
LIG_APCC_ABBA_1 307 312 PF00400 0.234
LIG_APCC_ABBA_1 414 419 PF00400 0.249
LIG_BIR_II_1 1 5 PF00653 0.531
LIG_BRCT_BRCA1_1 203 207 PF00533 0.293
LIG_BRCT_BRCA1_1 225 229 PF00533 0.234
LIG_BRCT_BRCA1_1 643 647 PF00533 0.243
LIG_BRCT_BRCA1_1 734 738 PF00533 0.234
LIG_Clathr_ClatBox_1 161 165 PF01394 0.249
LIG_CSL_BTD_1 342 345 PF09270 0.234
LIG_deltaCOP1_diTrp_1 312 321 PF00928 0.234
LIG_EH1_1 652 660 PF00400 0.234
LIG_eIF4E_1 653 659 PF01652 0.249
LIG_FHA_1 100 106 PF00498 0.246
LIG_FHA_1 197 203 PF00498 0.295
LIG_FHA_1 210 216 PF00498 0.222
LIG_FHA_1 43 49 PF00498 0.420
LIG_FHA_1 438 444 PF00498 0.249
LIG_FHA_1 479 485 PF00498 0.251
LIG_FHA_1 51 57 PF00498 0.390
LIG_FHA_1 618 624 PF00498 0.234
LIG_FHA_1 632 638 PF00498 0.234
LIG_FHA_1 732 738 PF00498 0.388
LIG_FHA_1 86 92 PF00498 0.453
LIG_FHA_2 242 248 PF00498 0.379
LIG_FHA_2 326 332 PF00498 0.234
LIG_FHA_2 357 363 PF00498 0.234
LIG_FHA_2 693 699 PF00498 0.391
LIG_LIR_Apic_2 444 448 PF02991 0.298
LIG_LIR_Apic_2 695 700 PF02991 0.379
LIG_LIR_Gen_1 145 156 PF02991 0.234
LIG_LIR_Gen_1 198 208 PF02991 0.234
LIG_LIR_Gen_1 239 250 PF02991 0.234
LIG_LIR_Gen_1 355 363 PF02991 0.272
LIG_LIR_Gen_1 375 384 PF02991 0.436
LIG_LIR_Gen_1 398 408 PF02991 0.234
LIG_LIR_Gen_1 521 531 PF02991 0.249
LIG_LIR_Gen_1 541 551 PF02991 0.262
LIG_LIR_Gen_1 561 572 PF02991 0.115
LIG_LIR_Gen_1 593 602 PF02991 0.249
LIG_LIR_Nem_3 101 106 PF02991 0.351
LIG_LIR_Nem_3 145 151 PF02991 0.234
LIG_LIR_Nem_3 239 245 PF02991 0.234
LIG_LIR_Nem_3 317 322 PF02991 0.234
LIG_LIR_Nem_3 337 342 PF02991 0.113
LIG_LIR_Nem_3 375 380 PF02991 0.282
LIG_LIR_Nem_3 398 404 PF02991 0.234
LIG_LIR_Nem_3 493 499 PF02991 0.256
LIG_LIR_Nem_3 541 546 PF02991 0.262
LIG_LIR_Nem_3 561 567 PF02991 0.115
LIG_LIR_Nem_3 593 597 PF02991 0.249
LIG_LIR_Nem_3 628 633 PF02991 0.293
LIG_LIR_Nem_3 644 650 PF02991 0.230
LIG_LIR_Nem_3 691 696 PF02991 0.234
LIG_PALB2_WD40_1 396 404 PF16756 0.234
LIG_Pex14_2 339 343 PF04695 0.234
LIG_REV1ctd_RIR_1 148 158 PF16727 0.268
LIG_SH2_CRK 242 246 PF00017 0.234
LIG_SH2_CRK 445 449 PF00017 0.200
LIG_SH2_NCK_1 445 449 PF00017 0.298
LIG_SH2_SRC 310 313 PF00017 0.234
LIG_SH2_STAP1 142 146 PF00017 0.300
LIG_SH2_STAP1 340 344 PF00017 0.268
LIG_SH2_STAT3 295 298 PF00017 0.234
LIG_SH2_STAT3 714 717 PF00017 0.268
LIG_SH2_STAT5 160 163 PF00017 0.298
LIG_SH2_STAT5 271 274 PF00017 0.234
LIG_SH2_STAT5 295 298 PF00017 0.234
LIG_SH2_STAT5 310 313 PF00017 0.234
LIG_SH2_STAT5 445 448 PF00017 0.249
LIG_SH2_STAT5 478 481 PF00017 0.347
LIG_SH2_STAT5 547 550 PF00017 0.328
LIG_SH2_STAT5 638 641 PF00017 0.243
LIG_SH2_STAT5 653 656 PF00017 0.345
LIG_SH2_STAT5 714 717 PF00017 0.296
LIG_SH2_STAT5 739 742 PF00017 0.232
LIG_SH2_STAT5 751 754 PF00017 0.302
LIG_SH3_3 171 177 PF00018 0.249
LIG_TRAF2_1 447 450 PF00917 0.379
LIG_TYR_ITIM 56 61 PF00017 0.410
LIG_WRC_WIRS_1 100 105 PF05994 0.304
LIG_WRC_WIRS_1 564 569 PF05994 0.293
MOD_CDK_SPK_2 217 222 PF00069 0.379
MOD_CK1_1 570 576 PF00069 0.234
MOD_CK1_1 678 684 PF00069 0.262
MOD_CK1_1 727 733 PF00069 0.264
MOD_CK1_1 779 785 PF00069 0.662
MOD_CK2_1 241 247 PF00069 0.379
MOD_CK2_1 403 409 PF00069 0.249
MOD_CK2_1 444 450 PF00069 0.265
MOD_CK2_1 550 556 PF00069 0.459
MOD_CK2_1 593 599 PF00069 0.318
MOD_CK2_1 692 698 PF00069 0.379
MOD_CK2_1 786 792 PF00069 0.589
MOD_CK2_1 95 101 PF00069 0.333
MOD_Cter_Amidation 300 303 PF01082 0.234
MOD_GlcNHglycan 3 6 PF01048 0.490
MOD_GlcNHglycan 531 534 PF01048 0.379
MOD_GlcNHglycan 588 591 PF01048 0.249
MOD_GlcNHglycan 643 646 PF01048 0.234
MOD_GlcNHglycan 729 732 PF01048 0.358
MOD_GSK3_1 152 159 PF00069 0.228
MOD_GSK3_1 230 237 PF00069 0.452
MOD_GSK3_1 272 279 PF00069 0.265
MOD_GSK3_1 403 410 PF00069 0.252
MOD_GSK3_1 42 49 PF00069 0.365
MOD_GSK3_1 429 436 PF00069 0.243
MOD_GSK3_1 444 451 PF00069 0.209
MOD_GSK3_1 478 485 PF00069 0.269
MOD_GSK3_1 498 505 PF00069 0.169
MOD_GSK3_1 563 570 PF00069 0.293
MOD_GSK3_1 614 621 PF00069 0.226
MOD_GSK3_1 65 72 PF00069 0.268
MOD_GSK3_1 671 678 PF00069 0.379
MOD_GSK3_1 727 734 PF00069 0.250
MOD_GSK3_1 782 789 PF00069 0.540
MOD_GSK3_1 95 102 PF00069 0.322
MOD_N-GLC_1 275 280 PF02516 0.256
MOD_N-GLC_1 289 294 PF02516 0.193
MOD_N-GLC_1 46 51 PF02516 0.379
MOD_N-GLC_1 664 669 PF02516 0.274
MOD_N-GLC_1 675 680 PF02516 0.201
MOD_N-GLC_1 95 100 PF02516 0.441
MOD_N-GLC_2 364 366 PF02516 0.379
MOD_N-GLC_2 437 439 PF02516 0.234
MOD_N-GLC_2 627 629 PF02516 0.234
MOD_NEK2_1 1 6 PF00069 0.596
MOD_NEK2_1 156 161 PF00069 0.234
MOD_NEK2_1 289 294 PF00069 0.379
MOD_NEK2_1 476 481 PF00069 0.361
MOD_NEK2_1 606 611 PF00069 0.231
MOD_NEK2_1 692 697 PF00069 0.411
MOD_NEK2_1 86 91 PF00069 0.234
MOD_NEK2_1 99 104 PF00069 0.297
MOD_NEK2_2 664 669 PF00069 0.361
MOD_NEK2_2 87 92 PF00069 0.379
MOD_PIKK_1 403 409 PF00454 0.249
MOD_PIKK_1 618 624 PF00454 0.234
MOD_PIKK_1 715 721 PF00454 0.234
MOD_PIKK_1 776 782 PF00454 0.658
MOD_PIKK_1 786 792 PF00454 0.589
MOD_PK_1 234 240 PF00069 0.249
MOD_PKA_1 325 331 PF00069 0.234
MOD_PKA_2 196 202 PF00069 0.379
MOD_PKA_2 325 331 PF00069 0.328
MOD_PKA_2 502 508 PF00069 0.249
MOD_PKA_2 606 612 PF00069 0.234
MOD_PKA_2 786 792 PF00069 0.589
MOD_Plk_1 156 162 PF00069 0.228
MOD_Plk_1 234 240 PF00069 0.234
MOD_Plk_1 551 557 PF00069 0.296
MOD_Plk_1 664 670 PF00069 0.361
MOD_Plk_1 95 101 PF00069 0.386
MOD_Plk_2-3 135 141 PF00069 0.295
MOD_Plk_2-3 593 599 PF00069 0.293
MOD_Plk_4 135 141 PF00069 0.481
MOD_Plk_4 211 217 PF00069 0.253
MOD_Plk_4 267 273 PF00069 0.249
MOD_Plk_4 542 548 PF00069 0.234
MOD_Plk_4 606 612 PF00069 0.244
MOD_Plk_4 675 681 PF00069 0.399
MOD_Plk_4 732 738 PF00069 0.393
MOD_Plk_4 95 101 PF00069 0.315
MOD_ProDKin_1 209 215 PF00069 0.234
MOD_ProDKin_1 217 223 PF00069 0.234
MOD_ProDKin_1 444 450 PF00069 0.298
MOD_ProDKin_1 567 573 PF00069 0.234
MOD_ProDKin_1 724 730 PF00069 0.328
MOD_SUMO_for_1 352 355 PF00179 0.379
MOD_SUMO_rev_2 354 359 PF00179 0.335
TRG_AP2beta_CARGO_1 317 326 PF09066 0.328
TRG_DiLeu_BaEn_1 101 106 PF01217 0.443
TRG_DiLeu_BaEn_1 157 162 PF01217 0.234
TRG_DiLeu_BaEn_1 198 203 PF01217 0.293
TRG_DiLeu_BaEn_4 375 381 PF01217 0.305
TRG_DiLeu_BaLyEn_6 116 121 PF01217 0.323
TRG_DiLeu_LyEn_5 101 106 PF01217 0.443
TRG_ENDOCYTIC_2 153 156 PF00928 0.262
TRG_ENDOCYTIC_2 200 203 PF00928 0.234
TRG_ENDOCYTIC_2 242 245 PF00928 0.234
TRG_ENDOCYTIC_2 496 499 PF00928 0.277
TRG_ENDOCYTIC_2 564 567 PF00928 0.299
TRG_ENDOCYTIC_2 58 61 PF00928 0.379
TRG_ENDOCYTIC_2 653 656 PF00928 0.294
TRG_ENDOCYTIC_2 693 696 PF00928 0.234
TRG_ENDOCYTIC_2 79 82 PF00928 0.263
TRG_ER_diArg_1 23 26 PF00400 0.356
TRG_ER_diArg_1 349 351 PF00400 0.255
TRG_ER_diArg_1 507 510 PF00400 0.268
TRG_ER_diArg_1 639 641 PF00400 0.234
TRG_ER_FFAT_2 441 451 PF00635 0.298
TRG_Pf-PMV_PEXEL_1 104 108 PF00026 0.377
TRG_Pf-PMV_PEXEL_1 144 149 PF00026 0.428
TRG_Pf-PMV_PEXEL_1 50 54 PF00026 0.341
TRG_Pf-PMV_PEXEL_1 641 646 PF00026 0.234
TRG_Pf-PMV_PEXEL_1 661 666 PF00026 0.113
TRG_Pf-PMV_PEXEL_1 702 706 PF00026 0.259

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PEL5 Leptomonas seymouri 88% 99%
A0A0S4IWY8 Bodo saltans 71% 100%
A0A1X0NYF0 Trypanosomatidae 72% 100%
A0A3S7X1E7 Leishmania donovani 100% 100%
A0A422N3W6 Trypanosoma rangeli 71% 100%
A4HGD3 Leishmania braziliensis 96% 100%
D0A7X4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 66% 95%
E9AZQ5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 100%
O15909 Trypanosoma brucei brucei 66% 95%
O36411 Alcelaphine herpesvirus 1 (strain C500) 26% 100%
O54196 Streptomyces clavuligerus 23% 83%
O61065 Cryptosporidium parvum 54% 100%
O66503 Aquifex aeolicus (strain VF5) 31% 100%
O69981 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) 22% 83%
O83972 Treponema pallidum (strain Nichols) 34% 95%
O84834 Chlamydia trachomatis (strain D/UW-3/Cx) 39% 76%
P00452 Escherichia coli (strain K12) 27% 100%
P03190 Epstein-Barr virus (strain B95-8) 26% 97%
P07742 Mus musculus 57% 100%
P08543 Human herpesvirus 1 (strain 17) 30% 70%
P09248 Varicella-zoster virus (strain Dumas) 29% 100%
P09853 Human herpesvirus 2 (strain 333) 30% 70%
P0A5W9 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 27% 100%
P0C702 Epstein-Barr virus (strain AG876) 26% 97%
P0C8H7 African swine fever virus (isolate Pig/Kenya/KEN-50/1950) 39% 100%
P0C8H8 African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) 39% 100%
P0C8H9 African swine fever virus (isolate Warthog/Namibia/Wart80/1980) 39% 100%
P0CG99 Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) 28% 100%
P0CH00 Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) 28% 100%
P0DSV1 Variola virus (isolate Human/India/Ind3/1967) 56% 100%
P0DSV2 Variola virus 56% 100%
P12848 Vaccinia virus (strain Western Reserve) 56% 100%
P16782 Human cytomegalovirus (strain AD169) 22% 88%
P20503 Vaccinia virus (strain Copenhagen) 56% 100%
P21524 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 61% 90%
P21672 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 60% 92%
P23921 Homo sapiens 57% 100%
P26685 African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) 38% 100%
P28846 Equine herpesvirus 1 (strain Ab4p) 31% 100%
P32282 Enterobacteria phage T4 28% 100%
P36602 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 60% 99%
P37426 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 27% 100%
P39452 Escherichia coli (strain K12) 27% 100%
P42491 African swine fever virus (strain Badajoz 1971 Vero-adapted) 38% 100%
P43754 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) 28% 100%
P47473 Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) 26% 100%
P48591 Drosophila melanogaster 55% 98%
P50620 Bacillus subtilis (strain 168) 25% 100%
P50642 Equine herpesvirus 4 (strain 1942) 31% 100%
P50643 Suid herpesvirus 1 (strain Kaplan) 30% 96%
P50646 Bovine herpesvirus 1.1 (strain Cooper) 31% 100%
P50647 Plasmodium falciparum (isolate FCR-3 / Gambia) 57% 99%
P50648 Plasmodium falciparum (isolate Dd2) 59% 99%
P55982 Helicobacter pylori (strain ATCC 700392 / 26695) 32% 100%
P57276 Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) 26% 100%
P74240 Synechocystis sp. (strain PCC 6803 / Kazusa) 28% 100%
P78027 Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) 25% 100%
P79732 Danio rerio 59% 100%
P89462 Human herpesvirus 2 (strain HG52) 30% 70%
P9WH74 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 27% 100%
P9WH75 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 27% 100%
P9WH76 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 26% 100%
P9WH77 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 26% 100%
Q01037 Saimiriine herpesvirus 2 (strain 11) 27% 100%
Q03604 Caenorhabditis elegans 58% 100%
Q08698 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 27% 100%
Q196Z5 Invertebrate iridescent virus 3 27% 100%
Q2HR67 Human herpesvirus 8 type P (isolate GK18) 28% 100%
Q3KSU5 Epstein-Barr virus (strain GD1) 26% 97%
Q4JQV6 Varicella-zoster virus (strain Oka vaccine) 29% 100%
Q4Q8H8 Leishmania major 98% 100%
Q54Q71 Dictyostelium discoideum 61% 92%
Q5R919 Pongo abelii 56% 100%
Q66663 Equine herpesvirus 2 (strain 86/87) 26% 100%
Q6GZT8 Frog virus 3 (isolate Goorha) 30% 100%
Q6MNP6 Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100) 24% 100%
Q6R7H4 Ostreid herpesvirus 1 (isolate France) 32% 96%
Q6SW87 Human cytomegalovirus (strain Merlin) 22% 88%
Q6UDJ2 Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) 28% 99%
Q76RD8 Vaccinia virus (strain Ankara) 56% 100%
Q77MS1 Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) 32% 97%
Q7T6Y8 Acanthamoeba polyphaga mimivirus 48% 91%
Q7UI46 Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1) 23% 77%
Q82KE2 Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) 22% 83%
Q89AS4 Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) 26% 100%
Q8F3P1 Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) 24% 67%
Q8K9W3 Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) 26% 100%
Q8SR37 Encephalitozoon cuniculi (strain GB-M1) 50% 100%
Q9CBQ0 Mycobacterium leprae (strain TN) 26% 100%
Q9PL93 Chlamydia muridarum (strain MoPn / Nigg) 36% 76%
Q9SJ20 Arabidopsis thaliana 59% 98%
Q9UW15 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 60% 86%
Q9Z6S5 Chlamydia pneumoniae 36% 77%
Q9ZLF9 Helicobacter pylori (strain J99 / ATCC 700824) 32% 100%
V5DH46 Trypanosoma cruzi 72% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS