Putative RNA binding protein rbp16

Quick info Annotations Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA binding protein rbp16 - putative

Species:

Leishmania infantum

UniProt:

A4I3F8_LEIIN

TriTrypDb:

LINF_280013700

Length:

143

Annotations

Annotations by Jardim et al.

Nucleic acid binding, RNA binding rbp16

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0005737	cytoplasm	2	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4I3F8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I3F8

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	11
GO:0005488	binding	1	11
GO:0097159	organic cyclic compound binding	2	11
GO:1901363	heterocyclic compound binding	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	40	42	PF00082	0.170
CLV_PCSK_PC1ET2_1	40	42	PF00082	0.170
DEG_Nend_Nbox_1	1	3	PF02207	0.464
DOC_MAPK_gen_1	40	47	PF00069	0.408
DOC_MAPK_MEF2A_6	9	16	PF00069	0.593
DOC_PP1_RVXF_1	19	26	PF00149	0.229
LIG_14-3-3_CanoR_1	3	8	PF00244	0.538
LIG_AP2alpha_1	139	143	PF02296	0.545
LIG_BRCT_BRCA1_1	139	143	PF00533	0.521
LIG_FHA_1	17	23	PF00498	0.426
LIG_FHA_2	75	81	PF00498	0.414
LIG_LIR_Nem_3	54	60	PF02991	0.408
LIG_PDZ_Class_3	138	143	PF00595	0.503
LIG_Pex14_2	139	143	PF04695	0.545
LIG_SH2_CRK	57	61	PF00017	0.489
LIG_SH3_3	79	85	PF00018	0.408
LIG_SH3_3	88	94	PF00018	0.504
LIG_SUMO_SIM_anti_2	13	19	PF11976	0.551
MOD_CK1_1	24	30	PF00069	0.394
MOD_CK1_1	5	11	PF00069	0.554
MOD_CK2_1	74	80	PF00069	0.409
MOD_GlcNHglycan	101	104	PF01048	0.567
MOD_GlcNHglycan	26	29	PF01048	0.194
MOD_GlcNHglycan	47	50	PF01048	0.220
MOD_GlcNHglycan	91	94	PF01048	0.530
MOD_GSK3_1	45	52	PF00069	0.394
MOD_N-GLC_1	137	142	PF02516	0.561
MOD_N-GLC_1	80	85	PF02516	0.208
MOD_NEK2_1	16	21	PF00069	0.476
MOD_NEK2_1	2	7	PF00069	0.535
MOD_PIKK_1	69	75	PF00454	0.394
MOD_PK_1	3	9	PF00069	0.517
MOD_PKA_2	117	123	PF00069	0.679
MOD_PKA_2	2	8	PF00069	0.494
MOD_Plk_4	21	27	PF00069	0.325
TRG_ENDOCYTIC_2	57	60	PF00928	0.489
TRG_Pf-PMV_PEXEL_1	58	63	PF00026	0.241

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDL5	Leptomonas seymouri	77%	99%
A0A0S4IK01	Bodo saltans	69%	88%
A0A1X0NZ24	Trypanosomatidae	82%	100%
A0A3S7X1B7	Leishmania donovani	99%	100%
A0A422N385	Trypanosoma rangeli	83%	100%
A4HGC6	Leishmania braziliensis	87%	100%
D0A7Y1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	82%	100%
E9AZP7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	99%
Q4Q8I6	Leishmania major	97%	99%