Neogenin_C domain-containing protein

Quick info Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I3F0_LEIIN

TriTrypDb:

LINF_280012700

Length:

222

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Phosphorylation

Promastigote: 100

Expansion

Sequence features

A4I3F0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I3F0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	95	99	PF00656	0.788
CLV_NRD_NRD_1	187	189	PF00675	0.525
CLV_PCSK_KEX2_1	187	189	PF00082	0.477
CLV_PCSK_SKI1_1	150	154	PF00082	0.476
CLV_PCSK_SKI1_1	178	182	PF00082	0.596
DOC_CYCLIN_RxL_1	174	185	PF00134	0.476
DOC_MAPK_MEF2A_6	213	222	PF00069	0.557
DOC_MAPK_MEF2A_6	29	36	PF00069	0.746
DOC_PP4_FxxP_1	28	31	PF00568	0.652
DOC_USP7_MATH_1	102	106	PF00917	0.750
DOC_WW_Pin1_4	104	109	PF00397	0.653
DOC_WW_Pin1_4	7	12	PF00397	0.663
DOC_WW_Pin1_4	97	102	PF00397	0.685
LIG_14-3-3_CanoR_1	104	108	PF00244	0.659
LIG_14-3-3_CanoR_1	213	219	PF00244	0.595
LIG_14-3-3_CanoR_1	3	8	PF00244	0.673
LIG_14-3-3_CanoR_1	54	61	PF00244	0.534
LIG_14-3-3_CanoR_1	89	97	PF00244	0.779
LIG_Actin_WH2_2	90	106	PF00022	0.773
LIG_BIR_II_1	1	5	PF00653	0.678
LIG_BRCT_BRCA1_1	106	110	PF00533	0.647
LIG_FAT_LD_1	197	205	PF03623	0.595
LIG_FHA_2	61	67	PF00498	0.780
LIG_LIR_Apic_2	25	31	PF02991	0.420
LIG_LIR_Apic_2	5	11	PF02991	0.660
LIG_MYND_1	11	15	PF01753	0.661
LIG_MYND_1	71	75	PF01753	0.641
LIG_PDZ_Class_2	217	222	PF00595	0.641
LIG_PTAP_UEV_1	14	19	PF05743	0.648
LIG_SH2_CRK	116	120	PF00017	0.638
LIG_SH2_PTP2	8	11	PF00017	0.658
LIG_SH2_STAP1	111	115	PF00017	0.723
LIG_SH2_STAT5	111	114	PF00017	0.728
LIG_SH2_STAT5	8	11	PF00017	0.658
LIG_SH3_3	12	18	PF00018	0.627
LIG_SH3_3	24	30	PF00018	0.540
LIG_SH3_3	71	77	PF00018	0.768
LIG_WW_1	108	111	PF00397	0.729
LIG_WW_1	52	55	PF00397	0.696
LIG_WW_3	51	55	PF00397	0.520
MOD_CDK_SPxxK_3	97	104	PF00069	0.682
MOD_CK1_1	139	145	PF00069	0.732
MOD_CK1_1	2	8	PF00069	0.672
MOD_CK2_1	60	66	PF00069	0.784
MOD_DYRK1A_RPxSP_1	104	108	PF00069	0.743
MOD_GlcNHglycan	138	141	PF01048	0.690
MOD_GlcNHglycan	38	41	PF01048	0.649
MOD_GlcNHglycan	55	58	PF01048	0.620
MOD_GSK3_1	214	221	PF00069	0.635
MOD_GSK3_1	3	10	PF00069	0.639
MOD_GSK3_1	32	39	PF00069	0.660
MOD_GSK3_1	88	95	PF00069	0.749
MOD_NEK2_1	1	6	PF00069	0.630
MOD_NEK2_1	103	108	PF00069	0.745
MOD_NEK2_1	214	219	PF00069	0.586
MOD_PIKK_1	109	115	PF00454	0.722
MOD_PIKK_1	187	193	PF00454	0.524
MOD_PKA_1	169	175	PF00069	0.513
MOD_PKA_1	187	193	PF00069	0.524
MOD_PKA_2	103	109	PF00069	0.656
MOD_PKA_2	187	193	PF00069	0.524
MOD_PKA_2	2	8	PF00069	0.672
MOD_PKA_2	53	59	PF00069	0.530
MOD_PKA_2	88	94	PF00069	0.774
MOD_Plk_4	119	125	PF00069	0.723
MOD_Plk_4	3	9	PF00069	0.674
MOD_ProDKin_1	104	110	PF00069	0.652
MOD_ProDKin_1	7	13	PF00069	0.665
MOD_ProDKin_1	97	103	PF00069	0.683
MOD_SUMO_for_1	168	171	PF00179	0.525
TRG_DiLeu_BaEn_2	161	167	PF01217	0.519
TRG_DiLeu_BaEn_4	162	168	PF01217	0.521
TRG_ENDOCYTIC_2	116	119	PF00928	0.639
TRG_ER_diArg_1	186	188	PF00400	0.527
TRG_NES_CRM1_1	193	206	PF08389	0.597
TRG_Pf-PMV_PEXEL_1	174	179	PF00026	0.514

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I075	Leptomonas seymouri	61%	100%
A0A3Q8IEI3	Leishmania donovani	99%	100%