LeishMANIAdb
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RAD50 DNA repair-like protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
RAD50 DNA repair-like protein
Gene product:
RAD50 DNA repair-like protein
Species:
Leishmania infantum
UniProt:
A4I3C7_LEIIN
TriTrypDb:
LINF_280010300
Length:
1360

Annotations

Annotations by Jardim et al.

DNA repair, RAD50 DNA repair-like

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0030870 Mre11 complex 3 10
GO:0032991 protein-containing complex 1 10
GO:0140513 nuclear protein-containing complex 2 10
GO:0000228 nuclear chromosome 6 1
GO:0000793 condensed chromosome 6 1
GO:0000794 condensed nuclear chromosome 7 1
GO:0005634 nucleus 5 1
GO:0005694 chromosome 5 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4I3C7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I3C7

Function

Biological processes
Term Name Level Count
GO:0000723 telomere maintenance 5 10
GO:0006139 nucleobase-containing compound metabolic process 3 10
GO:0006259 DNA metabolic process 4 10
GO:0006281 DNA repair 5 10
GO:0006725 cellular aromatic compound metabolic process 3 10
GO:0006807 nitrogen compound metabolic process 2 10
GO:0006950 response to stress 2 10
GO:0006974 DNA damage response 4 10
GO:0006996 organelle organization 4 10
GO:0008152 metabolic process 1 10
GO:0009987 cellular process 1 10
GO:0016043 cellular component organization 3 10
GO:0032200 telomere organization 6 10
GO:0033554 cellular response to stress 3 10
GO:0034641 cellular nitrogen compound metabolic process 3 10
GO:0043170 macromolecule metabolic process 3 10
GO:0044237 cellular metabolic process 2 10
GO:0044238 primary metabolic process 2 10
GO:0044260 obsolete cellular macromolecule metabolic process 3 10
GO:0046483 heterocycle metabolic process 3 10
GO:0050896 response to stimulus 1 10
GO:0051276 chromosome organization 5 10
GO:0051716 cellular response to stimulus 2 10
GO:0071704 organic substance metabolic process 2 10
GO:0071840 cellular component organization or biogenesis 2 10
GO:0090304 nucleic acid metabolic process 4 10
GO:1901360 organic cyclic compound metabolic process 3 10
GO:0000722 telomere maintenance via recombination 6 1
GO:0006278 RNA-templated DNA biosynthetic process 6 1
GO:0006302 double-strand break repair 6 1
GO:0006310 DNA recombination 5 1
GO:0006312 mitotic recombination 6 1
GO:0007004 telomere maintenance via telomerase 7 1
GO:0009058 biosynthetic process 2 1
GO:0009059 macromolecule biosynthetic process 4 1
GO:0010833 telomere maintenance via telomere lengthening 6 1
GO:0018130 heterocycle biosynthetic process 4 1
GO:0019438 aromatic compound biosynthetic process 4 1
GO:0022402 cell cycle process 2 1
GO:0022414 reproductive process 1 1
GO:0032392 DNA geometric change 7 1
GO:0032508 DNA duplex unwinding 8 1
GO:0034654 nucleobase-containing compound biosynthetic process 4 1
GO:0044249 cellular biosynthetic process 3 1
GO:0044271 cellular nitrogen compound biosynthetic process 4 1
GO:0070192 chromosome organization involved in meiotic cell cycle 3 1
GO:0071103 DNA conformation change 6 1
GO:0071897 DNA biosynthetic process 5 1
GO:0090305 nucleic acid phosphodiester bond hydrolysis 5 1
GO:1901362 organic cyclic compound biosynthetic process 4 1
GO:1901576 organic substance biosynthetic process 3 1
GO:1903046 meiotic cell cycle process 2 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 12
GO:0003824 catalytic activity 1 12
GO:0005488 binding 1 12
GO:0005524 ATP binding 5 12
GO:0008094 ATP-dependent activity, acting on DNA 2 10
GO:0016462 pyrophosphatase activity 5 10
GO:0016787 hydrolase activity 2 12
GO:0016817 hydrolase activity, acting on acid anhydrides 3 10
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 10
GO:0016887 ATP hydrolysis activity 7 10
GO:0017076 purine nucleotide binding 4 12
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 10
GO:0030554 adenyl nucleotide binding 5 12
GO:0032553 ribonucleotide binding 3 12
GO:0032555 purine ribonucleotide binding 4 12
GO:0032559 adenyl ribonucleotide binding 5 12
GO:0035639 purine ribonucleoside triphosphate binding 4 12
GO:0036094 small molecule binding 2 12
GO:0043167 ion binding 2 12
GO:0043168 anion binding 3 12
GO:0043169 cation binding 3 12
GO:0046872 metal ion binding 4 12
GO:0097159 organic cyclic compound binding 2 12
GO:0097367 carbohydrate derivative binding 2 12
GO:0140097 catalytic activity, acting on DNA 3 10
GO:0140299 small molecule sensor activity 1 10
GO:0140612 DNA damage sensor activity 2 10
GO:0140640 catalytic activity, acting on a nucleic acid 2 10
GO:0140657 ATP-dependent activity 1 10
GO:0140664 ATP-dependent DNA damage sensor activity 3 10
GO:1901265 nucleoside phosphate binding 3 12
GO:1901363 heterocyclic compound binding 2 12
GO:0003676 nucleic acid binding 3 1
GO:0003677 DNA binding 4 1
GO:0003690 double-stranded DNA binding 5 1
GO:0003691 double-stranded telomeric DNA binding 6 1
GO:0003697 single-stranded DNA binding 5 1
GO:0042162 telomeric DNA binding 6 1
GO:0043047 single-stranded telomeric DNA binding 7 1
GO:0043565 sequence-specific DNA binding 5 1
GO:0051880 G-quadruplex DNA binding 5 1
GO:0098847 sequence-specific single stranded DNA binding 6 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 114 118 PF00656 0.470
CLV_C14_Caspase3-7 1295 1299 PF00656 0.500
CLV_NRD_NRD_1 1040 1042 PF00675 0.507
CLV_NRD_NRD_1 1049 1051 PF00675 0.528
CLV_NRD_NRD_1 1230 1232 PF00675 0.214
CLV_NRD_NRD_1 1307 1309 PF00675 0.475
CLV_NRD_NRD_1 204 206 PF00675 0.214
CLV_NRD_NRD_1 286 288 PF00675 0.544
CLV_NRD_NRD_1 291 293 PF00675 0.581
CLV_NRD_NRD_1 337 339 PF00675 0.422
CLV_NRD_NRD_1 453 455 PF00675 0.480
CLV_NRD_NRD_1 494 496 PF00675 0.567
CLV_NRD_NRD_1 635 637 PF00675 0.421
CLV_NRD_NRD_1 714 716 PF00675 0.596
CLV_NRD_NRD_1 824 826 PF00675 0.429
CLV_NRD_NRD_1 843 845 PF00675 0.448
CLV_NRD_NRD_1 905 907 PF00675 0.508
CLV_PCSK_KEX2_1 1049 1051 PF00082 0.553
CLV_PCSK_KEX2_1 1154 1156 PF00082 0.365
CLV_PCSK_KEX2_1 1230 1232 PF00082 0.203
CLV_PCSK_KEX2_1 1240 1242 PF00082 0.203
CLV_PCSK_KEX2_1 1307 1309 PF00082 0.475
CLV_PCSK_KEX2_1 177 179 PF00082 0.307
CLV_PCSK_KEX2_1 204 206 PF00082 0.205
CLV_PCSK_KEX2_1 286 288 PF00082 0.513
CLV_PCSK_KEX2_1 291 293 PF00082 0.542
CLV_PCSK_KEX2_1 328 330 PF00082 0.435
CLV_PCSK_KEX2_1 336 338 PF00082 0.375
CLV_PCSK_KEX2_1 452 454 PF00082 0.475
CLV_PCSK_KEX2_1 635 637 PF00082 0.457
CLV_PCSK_KEX2_1 672 674 PF00082 0.514
CLV_PCSK_KEX2_1 945 947 PF00082 0.537
CLV_PCSK_PC1ET2_1 1154 1156 PF00082 0.365
CLV_PCSK_PC1ET2_1 1240 1242 PF00082 0.208
CLV_PCSK_PC1ET2_1 177 179 PF00082 0.307
CLV_PCSK_PC1ET2_1 328 330 PF00082 0.476
CLV_PCSK_PC1ET2_1 672 674 PF00082 0.390
CLV_PCSK_PC1ET2_1 945 947 PF00082 0.532
CLV_PCSK_PC7_1 1236 1242 PF00082 0.203
CLV_PCSK_PC7_1 282 288 PF00082 0.529
CLV_PCSK_SKI1_1 1265 1269 PF00082 0.203
CLV_PCSK_SKI1_1 1308 1312 PF00082 0.381
CLV_PCSK_SKI1_1 174 178 PF00082 0.205
CLV_PCSK_SKI1_1 188 192 PF00082 0.199
CLV_PCSK_SKI1_1 205 209 PF00082 0.170
CLV_PCSK_SKI1_1 29 33 PF00082 0.241
CLV_PCSK_SKI1_1 453 457 PF00082 0.467
CLV_PCSK_SKI1_1 558 562 PF00082 0.408
CLV_PCSK_SKI1_1 596 600 PF00082 0.532
CLV_PCSK_SKI1_1 673 677 PF00082 0.450
CLV_PCSK_SKI1_1 85 89 PF00082 0.230
CLV_PCSK_SKI1_1 882 886 PF00082 0.514
CLV_PCSK_SKI1_1 977 981 PF00082 0.429
DEG_APCC_DBOX_1 258 266 PF00400 0.523
DEG_APCC_DBOX_1 470 478 PF00400 0.483
DEG_APCC_DBOX_1 557 565 PF00400 0.416
DEG_APCC_DBOX_1 672 680 PF00400 0.506
DEG_APCC_KENBOX_2 455 459 PF00400 0.374
DEG_COP1_1 137 147 PF00400 0.452
DEG_SPOP_SBC_1 130 134 PF00917 0.446
DOC_ANK_TNKS_1 494 501 PF00023 0.395
DOC_CYCLIN_RxL_1 604 614 PF00134 0.389
DOC_CYCLIN_RxL_1 958 968 PF00134 0.549
DOC_CYCLIN_RxL_1 985 993 PF00134 0.529
DOC_MAPK_gen_1 1154 1163 PF00069 0.357
DOC_MAPK_gen_1 1307 1318 PF00069 0.329
DOC_MAPK_gen_1 346 353 PF00069 0.497
DOC_MAPK_gen_1 471 479 PF00069 0.395
DOC_MAPK_gen_1 755 763 PF00069 0.458
DOC_MAPK_gen_1 985 994 PF00069 0.446
DOC_MAPK_MEF2A_6 1007 1016 PF00069 0.459
DOC_MAPK_MEF2A_6 1257 1266 PF00069 0.403
DOC_MAPK_MEF2A_6 473 481 PF00069 0.475
DOC_MAPK_MEF2A_6 746 754 PF00069 0.476
DOC_MAPK_MEF2A_6 81 88 PF00069 0.403
DOC_MAPK_MEF2A_6 985 994 PF00069 0.455
DOC_MAPK_NFAT4_5 81 89 PF00069 0.414
DOC_PP1_RVXF_1 108 114 PF00149 0.507
DOC_PP1_RVXF_1 83 89 PF00149 0.403
DOC_PP2B_LxvP_1 170 173 PF13499 0.410
DOC_PP2B_LxvP_1 992 995 PF13499 0.522
DOC_PP4_FxxP_1 27 30 PF00568 0.403
DOC_USP7_MATH_1 104 108 PF00917 0.450
DOC_USP7_MATH_1 1183 1187 PF00917 0.363
DOC_USP7_MATH_1 1229 1233 PF00917 0.418
DOC_USP7_MATH_1 296 300 PF00917 0.471
DOC_USP7_MATH_1 412 416 PF00917 0.387
DOC_USP7_MATH_1 576 580 PF00917 0.551
DOC_USP7_MATH_1 678 682 PF00917 0.538
DOC_USP7_MATH_1 702 706 PF00917 0.452
DOC_USP7_MATH_1 708 712 PF00917 0.414
DOC_USP7_MATH_1 740 744 PF00917 0.358
DOC_USP7_MATH_1 859 863 PF00917 0.588
DOC_USP7_MATH_1 951 955 PF00917 0.438
DOC_USP7_UBL2_3 1038 1042 PF12436 0.436
DOC_WW_Pin1_4 148 153 PF00397 0.434
DOC_WW_Pin1_4 720 725 PF00397 0.431
LIG_14-3-3_CanoR_1 1041 1045 PF00244 0.563
LIG_14-3-3_CanoR_1 1079 1085 PF00244 0.524
LIG_14-3-3_CanoR_1 110 120 PF00244 0.419
LIG_14-3-3_CanoR_1 1101 1106 PF00244 0.537
LIG_14-3-3_CanoR_1 1155 1161 PF00244 0.342
LIG_14-3-3_CanoR_1 1204 1208 PF00244 0.361
LIG_14-3-3_CanoR_1 1230 1234 PF00244 0.413
LIG_14-3-3_CanoR_1 1249 1259 PF00244 0.345
LIG_14-3-3_CanoR_1 136 144 PF00244 0.500
LIG_14-3-3_CanoR_1 309 319 PF00244 0.617
LIG_14-3-3_CanoR_1 635 639 PF00244 0.347
LIG_14-3-3_CanoR_1 882 890 PF00244 0.533
LIG_Actin_WH2_2 248 265 PF00022 0.512
LIG_Actin_WH2_2 805 822 PF00022 0.507
LIG_AP2alpha_1 180 184 PF02296 0.446
LIG_APCC_ABBA_1 652 657 PF00400 0.288
LIG_BIR_III_4 769 773 PF00653 0.315
LIG_BRCT_BRCA1_1 1268 1272 PF00533 0.403
LIG_BRCT_BRCA1_1 199 203 PF00533 0.428
LIG_Clathr_ClatBox_1 508 512 PF01394 0.437
LIG_DLG_GKlike_1 1101 1108 PF00625 0.404
LIG_FHA_1 1111 1117 PF00498 0.479
LIG_FHA_1 1163 1169 PF00498 0.325
LIG_FHA_1 1212 1218 PF00498 0.338
LIG_FHA_1 125 131 PF00498 0.414
LIG_FHA_1 1283 1289 PF00498 0.403
LIG_FHA_1 185 191 PF00498 0.408
LIG_FHA_1 30 36 PF00498 0.403
LIG_FHA_1 41 47 PF00498 0.403
LIG_FHA_1 626 632 PF00498 0.402
LIG_FHA_1 693 699 PF00498 0.490
LIG_FHA_1 814 820 PF00498 0.517
LIG_FHA_1 872 878 PF00498 0.519
LIG_FHA_2 1041 1047 PF00498 0.610
LIG_FHA_2 1105 1111 PF00498 0.455
LIG_FHA_2 1115 1121 PF00498 0.445
LIG_FHA_2 112 118 PF00498 0.470
LIG_FHA_2 1284 1290 PF00498 0.403
LIG_FHA_2 1317 1323 PF00498 0.287
LIG_FHA_2 262 268 PF00498 0.506
LIG_FHA_2 299 305 PF00498 0.521
LIG_FHA_2 42 48 PF00498 0.403
LIG_FHA_2 59 65 PF00498 0.403
LIG_FHA_2 734 740 PF00498 0.411
LIG_FHA_2 809 815 PF00498 0.457
LIG_FHA_2 937 943 PF00498 0.561
LIG_Integrin_isoDGR_2 280 282 PF01839 0.408
LIG_Integrin_RGD_1 1145 1147 PF01839 0.454
LIG_LIR_Gen_1 112 121 PF02991 0.425
LIG_LIR_Gen_1 1147 1156 PF02991 0.387
LIG_LIR_Gen_1 1158 1168 PF02991 0.296
LIG_LIR_Gen_1 1174 1184 PF02991 0.343
LIG_LIR_Gen_1 1344 1355 PF02991 0.316
LIG_LIR_Gen_1 653 662 PF02991 0.366
LIG_LIR_Gen_1 681 690 PF02991 0.404
LIG_LIR_Gen_1 739 747 PF02991 0.405
LIG_LIR_Gen_1 800 809 PF02991 0.409
LIG_LIR_Gen_1 862 871 PF02991 0.402
LIG_LIR_Nem_3 112 116 PF02991 0.449
LIG_LIR_Nem_3 1147 1152 PF02991 0.365
LIG_LIR_Nem_3 1158 1163 PF02991 0.334
LIG_LIR_Nem_3 1174 1180 PF02991 0.302
LIG_LIR_Nem_3 119 125 PF02991 0.418
LIG_LIR_Nem_3 1232 1238 PF02991 0.414
LIG_LIR_Nem_3 1334 1339 PF02991 0.305
LIG_LIR_Nem_3 1344 1350 PF02991 0.317
LIG_LIR_Nem_3 1352 1358 PF02991 0.330
LIG_LIR_Nem_3 653 658 PF02991 0.352
LIG_LIR_Nem_3 681 686 PF02991 0.418
LIG_LIR_Nem_3 739 744 PF02991 0.405
LIG_LIR_Nem_3 800 806 PF02991 0.406
LIG_LIR_Nem_3 862 866 PF02991 0.410
LIG_LYPXL_SIV_4 869 877 PF13949 0.498
LIG_NRBOX 301 307 PF00104 0.560
LIG_NRBOX 390 396 PF00104 0.520
LIG_PCNA_yPIPBox_3 1191 1203 PF02747 0.313
LIG_PDZ_Class_2 1355 1360 PF00595 0.379
LIG_Pex14_1 1203 1207 PF04695 0.325
LIG_Pex14_2 1355 1359 PF04695 0.345
LIG_Pex14_2 180 184 PF04695 0.403
LIG_RPA_C_Fungi 544 556 PF08784 0.353
LIG_RPA_C_Fungi 658 670 PF08784 0.315
LIG_RPA_C_Plants 966 977 PF08784 0.410
LIG_SH2_CRK 1235 1239 PF00017 0.238
LIG_SH2_GRB2like 1149 1152 PF00017 0.415
LIG_SH2_NCK_1 330 334 PF00017 0.368
LIG_SH2_NCK_1 870 874 PF00017 0.367
LIG_SH2_SRC 1149 1152 PF00017 0.415
LIG_SH2_SRC 655 658 PF00017 0.337
LIG_SH2_STAP1 655 659 PF00017 0.418
LIG_SH2_STAT5 1000 1003 PF00017 0.407
LIG_SH2_STAT5 1338 1341 PF00017 0.335
LIG_SH2_STAT5 189 192 PF00017 0.286
LIG_SH2_STAT5 379 382 PF00017 0.667
LIG_SH3_2 169 174 PF14604 0.253
LIG_SH3_3 166 172 PF00018 0.253
LIG_SH3_3 566 572 PF00018 0.531
LIG_SH3_3 66 72 PF00018 0.238
LIG_SUMO_SIM_anti_2 537 542 PF11976 0.430
LIG_SUMO_SIM_par_1 1213 1222 PF11976 0.373
LIG_SUMO_SIM_par_1 1277 1283 PF11976 0.238
LIG_SUMO_SIM_par_1 1314 1319 PF11976 0.271
LIG_SUMO_SIM_par_1 189 194 PF11976 0.253
LIG_SUMO_SIM_par_1 609 614 PF11976 0.455
LIG_SUMO_SIM_par_1 814 822 PF11976 0.444
LIG_TRAF2_1 1026 1029 PF00917 0.435
LIG_TRAF2_1 258 261 PF00917 0.416
LIG_TRAF2_1 264 267 PF00917 0.403
LIG_TRAF2_1 339 342 PF00917 0.511
LIG_TRAF2_1 490 493 PF00917 0.478
LIG_TRAF2_1 690 693 PF00917 0.312
LIG_TRAF2_1 736 739 PF00917 0.442
LIG_TRAF2_1 862 865 PF00917 0.452
LIG_WRC_WIRS_1 12 17 PF05994 0.238
LIG_WRC_WIRS_1 709 714 PF05994 0.444
LIG_WRC_WIRS_1 99 104 PF05994 0.253
MOD_CK1_1 1083 1089 PF00069 0.568
MOD_CK1_1 1104 1110 PF00069 0.465
MOD_CK1_1 581 587 PF00069 0.413
MOD_CK1_1 625 631 PF00069 0.394
MOD_CK1_1 711 717 PF00069 0.513
MOD_CK2_1 1104 1110 PF00069 0.427
MOD_CK2_1 1114 1120 PF00069 0.345
MOD_CK2_1 1175 1181 PF00069 0.504
MOD_CK2_1 1216 1222 PF00069 0.481
MOD_CK2_1 1316 1322 PF00069 0.276
MOD_CK2_1 261 267 PF00069 0.407
MOD_CK2_1 41 47 PF00069 0.238
MOD_CK2_1 58 64 PF00069 0.238
MOD_CK2_1 624 630 PF00069 0.443
MOD_CK2_1 733 739 PF00069 0.373
MOD_CK2_1 808 814 PF00069 0.510
MOD_CK2_1 859 865 PF00069 0.483
MOD_CK2_1 915 921 PF00069 0.301
MOD_CK2_1 936 942 PF00069 0.590
MOD_GlcNHglycan 1020 1023 PF01048 0.506
MOD_GlcNHglycan 1050 1053 PF01048 0.559
MOD_GlcNHglycan 106 109 PF01048 0.383
MOD_GlcNHglycan 1177 1180 PF01048 0.395
MOD_GlcNHglycan 1252 1255 PF01048 0.238
MOD_GlcNHglycan 847 850 PF01048 0.702
MOD_GSK3_1 1110 1117 PF00069 0.468
MOD_GSK3_1 112 119 PF00069 0.180
MOD_GSK3_1 1162 1169 PF00069 0.469
MOD_GSK3_1 1203 1210 PF00069 0.350
MOD_GSK3_1 1218 1225 PF00069 0.420
MOD_GSK3_1 130 137 PF00069 0.419
MOD_GSK3_1 576 583 PF00069 0.491
MOD_GSK3_1 60 67 PF00069 0.231
MOD_GSK3_1 746 753 PF00069 0.555
MOD_GSK3_1 98 105 PF00069 0.245
MOD_N-GLC_1 514 519 PF02516 0.499
MOD_N-GLC_2 1003 1005 PF02516 0.444
MOD_N-GLC_2 51 53 PF02516 0.253
MOD_NEK2_1 102 107 PF00069 0.238
MOD_NEK2_1 116 121 PF00069 0.230
MOD_NEK2_1 184 189 PF00069 0.282
MOD_NEK2_1 308 313 PF00069 0.546
MOD_NEK2_1 580 585 PF00069 0.464
MOD_NEK2_1 808 813 PF00069 0.436
MOD_NEK2_1 819 824 PF00069 0.468
MOD_NEK2_1 86 91 PF00069 0.238
MOD_NEK2_1 990 995 PF00069 0.499
MOD_NEK2_2 678 683 PF00069 0.383
MOD_PIKK_1 296 302 PF00454 0.588
MOD_PIKK_1 501 507 PF00454 0.567
MOD_PIKK_1 587 593 PF00454 0.426
MOD_PIKK_1 839 845 PF00454 0.579
MOD_PK_1 746 752 PF00069 0.548
MOD_PKA_2 1016 1022 PF00069 0.535
MOD_PKA_2 1040 1046 PF00069 0.563
MOD_PKA_2 1048 1054 PF00069 0.514
MOD_PKA_2 109 115 PF00069 0.396
MOD_PKA_2 1156 1162 PF00069 0.343
MOD_PKA_2 1203 1209 PF00069 0.341
MOD_PKA_2 1229 1235 PF00069 0.253
MOD_PKA_2 1250 1256 PF00069 0.272
MOD_PKA_2 135 141 PF00069 0.372
MOD_PKA_2 308 314 PF00069 0.619
MOD_PKA_2 634 640 PF00069 0.565
MOD_PKA_2 819 825 PF00069 0.555
MOD_PKA_2 905 911 PF00069 0.572
MOD_PKB_1 195 203 PF00069 0.272
MOD_PKB_1 408 416 PF00069 0.404
MOD_Plk_1 1063 1069 PF00069 0.505
MOD_Plk_1 1077 1083 PF00069 0.395
MOD_Plk_1 116 122 PF00069 0.268
MOD_Plk_1 1166 1172 PF00069 0.463
MOD_Plk_1 1351 1357 PF00069 0.331
MOD_Plk_1 210 216 PF00069 0.297
MOD_Plk_1 387 393 PF00069 0.540
MOD_Plk_1 514 520 PF00069 0.476
MOD_Plk_1 813 819 PF00069 0.560
MOD_Plk_2-3 1211 1217 PF00069 0.334
MOD_Plk_2-3 1351 1357 PF00069 0.331
MOD_Plk_2-3 261 267 PF00069 0.484
MOD_Plk_4 1156 1162 PF00069 0.343
MOD_Plk_4 1258 1264 PF00069 0.243
MOD_Plk_4 210 216 PF00069 0.332
MOD_Plk_4 233 239 PF00069 0.425
MOD_Plk_4 29 35 PF00069 0.264
MOD_Plk_4 41 47 PF00069 0.238
MOD_Plk_4 64 70 PF00069 0.238
MOD_Plk_4 708 714 PF00069 0.490
MOD_Plk_4 746 752 PF00069 0.373
MOD_Plk_4 798 804 PF00069 0.361
MOD_Plk_4 996 1002 PF00069 0.421
MOD_ProDKin_1 148 154 PF00069 0.281
MOD_ProDKin_1 720 726 PF00069 0.427
MOD_SUMO_for_1 598 601 PF00179 0.411
MOD_SUMO_for_1 690 693 PF00179 0.367
MOD_SUMO_rev_2 67 75 PF00179 0.241
MOD_SUMO_rev_2 77 82 PF00179 0.243
MOD_SUMO_rev_2 900 909 PF00179 0.428
TRG_DiLeu_BaEn_2 63 69 PF01217 0.253
TRG_DiLeu_BaEn_4 601 607 PF01217 0.353
TRG_DiLeu_BaLyEn_6 390 395 PF01217 0.517
TRG_DiLeu_BaLyEn_6 82 87 PF01217 0.253
TRG_ENDOCYTIC_2 1149 1152 PF00928 0.355
TRG_ENDOCYTIC_2 1177 1180 PF00928 0.330
TRG_ENDOCYTIC_2 1235 1238 PF00928 0.238
TRG_ENDOCYTIC_2 655 658 PF00928 0.523
TRG_ENDOCYTIC_2 683 686 PF00928 0.352
TRG_ENDOCYTIC_2 741 744 PF00928 0.397
TRG_ENDOCYTIC_2 803 806 PF00928 0.367
TRG_ENDOCYTIC_2 863 866 PF00928 0.399
TRG_ER_diArg_1 1248 1251 PF00400 0.253
TRG_ER_diArg_1 203 205 PF00400 0.253
TRG_ER_diArg_1 290 292 PF00400 0.578
TRG_ER_diArg_1 336 338 PF00400 0.482
TRG_ER_diArg_1 451 454 PF00400 0.484
TRG_ER_diArg_1 758 761 PF00400 0.435
TRG_ER_diArg_1 938 941 PF00400 0.504
TRG_NES_CRM1_1 559 573 PF08389 0.506
TRG_Pf-PMV_PEXEL_1 1007 1011 PF00026 0.618
TRG_Pf-PMV_PEXEL_1 1294 1298 PF00026 0.238
TRG_Pf-PMV_PEXEL_1 1301 1305 PF00026 0.346
TRG_Pf-PMV_PEXEL_1 1326 1331 PF00026 0.359
TRG_Pf-PMV_PEXEL_1 205 209 PF00026 0.332
TRG_Pf-PMV_PEXEL_1 253 257 PF00026 0.546
TRG_Pf-PMV_PEXEL_1 369 373 PF00026 0.534
TRG_Pf-PMV_PEXEL_1 453 457 PF00026 0.537
TRG_Pf-PMV_PEXEL_1 506 510 PF00026 0.540
TRG_Pf-PMV_PEXEL_1 596 601 PF00026 0.388
TRG_Pf-PMV_PEXEL_1 609 614 PF00026 0.290
TRG_Pf-PMV_PEXEL_1 901 905 PF00026 0.555
TRG_Pf-PMV_PEXEL_1 928 932 PF00026 0.466
TRG_Pf-PMV_PEXEL_1 985 989 PF00026 0.517

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I3D5 Leptomonas seymouri 69% 100%
A0A0S4JAY7 Bodo saltans 38% 100%
A0A1X0NYH4 Trypanosomatidae 47% 100%
A0A3R7N260 Trypanosoma rangeli 47% 100%
A0A3S7X1A7 Leishmania donovani 100% 100%
A4HG93 Leishmania braziliensis 84% 100%
D0A818 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 45% 100%
E9AZL4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
P70388 Mus musculus 28% 100%
Q4Q8L7 Leishmania major 93% 100%
Q92878 Homo sapiens 28% 100%
V5BQC9 Trypanosoma cruzi 46% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS