Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I3B0_LEIIN

TriTrypDb:

LINF_280008500

Length:

520

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I3B0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I3B0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	301	305	PF00656	0.471
CLV_NRD_NRD_1	103	105	PF00675	0.389
CLV_NRD_NRD_1	249	251	PF00675	0.403
CLV_NRD_NRD_1	255	257	PF00675	0.399
CLV_NRD_NRD_1	273	275	PF00675	0.368
CLV_NRD_NRD_1	328	330	PF00675	0.390
CLV_NRD_NRD_1	382	384	PF00675	0.315
CLV_NRD_NRD_1	446	448	PF00675	0.315
CLV_PCSK_KEX2_1	103	105	PF00082	0.389
CLV_PCSK_KEX2_1	249	251	PF00082	0.403
CLV_PCSK_KEX2_1	255	257	PF00082	0.399
CLV_PCSK_KEX2_1	275	277	PF00082	0.351
CLV_PCSK_KEX2_1	328	330	PF00082	0.390
CLV_PCSK_KEX2_1	382	384	PF00082	0.315
CLV_PCSK_KEX2_1	446	448	PF00082	0.315
CLV_PCSK_PC1ET2_1	275	277	PF00082	0.351
CLV_PCSK_SKI1_1	168	172	PF00082	0.404
CLV_PCSK_SKI1_1	2	6	PF00082	0.515
CLV_PCSK_SKI1_1	266	270	PF00082	0.357
CLV_PCSK_SKI1_1	360	364	PF00082	0.305
CLV_PCSK_SKI1_1	366	370	PF00082	0.333
CLV_PCSK_SKI1_1	59	63	PF00082	0.405
DEG_APCC_DBOX_1	167	175	PF00400	0.386
DEG_APCC_DBOX_1	273	281	PF00400	0.355
DEG_Nend_UBRbox_1	1	4	PF02207	0.525
DEG_SPOP_SBC_1	38	42	PF00917	0.483
DOC_CKS1_1	187	192	PF01111	0.469
DOC_CYCLIN_RxL_1	165	173	PF00134	0.408
DOC_CYCLIN_RxL_1	357	367	PF00134	0.315
DOC_CYCLIN_yCln2_LP_2	105	111	PF00134	0.408
DOC_CYCLIN_yCln2_LP_2	511	517	PF00134	0.287
DOC_MAPK_DCC_7	255	263	PF00069	0.364
DOC_MAPK_DCC_7	272	282	PF00069	0.359
DOC_MAPK_gen_1	103	113	PF00069	0.400
DOC_MAPK_gen_1	255	263	PF00069	0.364
DOC_MAPK_gen_1	272	282	PF00069	0.359
DOC_MAPK_JIP1_4	513	519	PF00069	0.286
DOC_MAPK_MEF2A_6	104	113	PF00069	0.405
DOC_MAPK_MEF2A_6	274	282	PF00069	0.356
DOC_PP1_RVXF_1	101	108	PF00149	0.392
DOC_PP1_RVXF_1	445	452	PF00149	0.294
DOC_PP2B_LxvP_1	109	112	PF13499	0.414
DOC_PP2B_LxvP_1	435	438	PF13499	0.305
DOC_USP7_MATH_1	381	385	PF00917	0.315
DOC_USP7_MATH_1	501	505	PF00917	0.351
DOC_WW_Pin1_4	186	191	PF00397	0.463
DOC_WW_Pin1_4	344	349	PF00397	0.472
DOC_WW_Pin1_4	42	47	PF00397	0.488
DOC_WW_Pin1_4	440	445	PF00397	0.355
DOC_WW_Pin1_4	59	64	PF00397	0.400
LIG_14-3-3_CanoR_1	14	22	PF00244	0.374
LIG_14-3-3_CanoR_1	328	338	PF00244	0.426
LIG_14-3-3_CanoR_1	382	388	PF00244	0.312
LIG_14-3-3_CanoR_1	71	77	PF00244	0.350
LIG_14-3-3_CanoR_1	87	92	PF00244	0.351
LIG_Actin_WH2_2	355	372	PF00022	0.318
LIG_Actin_WH2_2	466	484	PF00022	0.260
LIG_APCC_ABBA_1	473	478	PF00400	0.247
LIG_BIR_III_2	304	308	PF00653	0.464
LIG_BIR_III_4	129	133	PF00653	0.407
LIG_BRCT_BRCA1_1	228	232	PF00533	0.402
LIG_BRCT_BRCA1_1	503	507	PF00533	0.311
LIG_BRCT_BRCA1_1	89	93	PF00533	0.347
LIG_Clathr_ClatBox_1	110	114	PF01394	0.408
LIG_deltaCOP1_diTrp_1	172	182	PF00928	0.359
LIG_DLG_GKlike_1	87	94	PF00625	0.351
LIG_EH1_1	63	71	PF00400	0.358
LIG_eIF4E_1	143	149	PF01652	0.323
LIG_FHA_1	14	20	PF00498	0.379
LIG_FHA_1	306	312	PF00498	0.454
LIG_FHA_1	39	45	PF00498	0.488
LIG_FHA_1	411	417	PF00498	0.297
LIG_FHA_1	72	78	PF00498	0.341
LIG_FHA_2	1	7	PF00498	0.515
LIG_FHA_2	291	297	PF00498	0.427
LIG_FHA_2	299	305	PF00498	0.463
LIG_FHA_2	314	320	PF00498	0.402
LIG_FHA_2	370	376	PF00498	0.324
LIG_LIR_Apic_2	180	185	PF02991	0.393
LIG_LIR_Apic_2	331	337	PF02991	0.435
LIG_LIR_Gen_1	504	515	PF02991	0.298
LIG_LIR_Nem_3	114	119	PF02991	0.414
LIG_LIR_Nem_3	172	178	PF02991	0.355
LIG_LIR_Nem_3	259	265	PF02991	0.337
LIG_LIR_Nem_3	386	391	PF02991	0.297
LIG_LIR_Nem_3	433	437	PF02991	0.293
LIG_LIR_Nem_3	504	510	PF02991	0.301
LIG_LYPXL_yS_3	116	119	PF13949	0.416
LIG_MYND_1	108	112	PF01753	0.405
LIG_NRBOX	212	218	PF00104	0.336
LIG_Pex14_2	232	236	PF04695	0.415
LIG_Pex14_2	263	267	PF04695	0.344
LIG_SH2_CRK	143	147	PF00017	0.328
LIG_SH2_CRK	334	338	PF00017	0.460
LIG_SH2_CRK	465	469	PF00017	0.229
LIG_SH2_GRB2like	391	394	PF00017	0.299
LIG_SH2_NCK_1	334	338	PF00017	0.460
LIG_SH2_STAP1	465	469	PF00017	0.229
LIG_SH2_STAT5	262	265	PF00017	0.343
LIG_SH3_3	342	348	PF00018	0.490
LIG_SH3_3	489	495	PF00018	0.431
LIG_SH3_3	497	503	PF00018	0.400
LIG_SH3_3	5	11	PF00018	0.474
LIG_SUMO_SIM_anti_2	210	218	PF11976	0.351
LIG_SUMO_SIM_anti_2	65	70	PF11976	0.341
LIG_SUMO_SIM_par_1	210	218	PF11976	0.351
LIG_TRAF2_1	315	318	PF00917	0.409
LIG_TRAF2_1	384	387	PF00917	0.325
LIG_ULM_U2AF65_1	103	108	PF00076	0.390
LIG_WRC_WIRS_1	297	302	PF05994	0.459
MOD_CDK_SPxK_1	440	446	PF00069	0.347
MOD_CDK_SPxxK_3	42	49	PF00069	0.488
MOD_CDK_SPxxK_3	440	447	PF00069	0.340
MOD_CK1_1	122	128	PF00069	0.431
MOD_CK1_1	164	170	PF00069	0.430
MOD_CK1_1	192	198	PF00069	0.496
MOD_CK1_1	212	218	PF00069	0.336
MOD_CK1_1	313	319	PF00069	0.410
MOD_CK1_1	332	338	PF00069	0.446
MOD_CK1_1	40	46	PF00069	0.490
MOD_CK1_1	410	416	PF00069	0.295
MOD_CK1_1	99	105	PF00069	0.379
MOD_CK2_1	122	128	PF00069	0.431
MOD_CK2_1	296	302	PF00069	0.455
MOD_CK2_1	311	317	PF00069	0.430
MOD_CK2_1	381	387	PF00069	0.319
MOD_Cter_Amidation	272	275	PF01082	0.373
MOD_DYRK1A_RPxSP_1	59	63	PF00069	0.405
MOD_GlcNHglycan	191	194	PF01048	0.484
MOD_GlcNHglycan	197	200	PF01048	0.506
MOD_GlcNHglycan	217	220	PF01048	0.314
MOD_GlcNHglycan	228	231	PF01048	0.402
MOD_GlcNHglycan	269	272	PF01048	0.376
MOD_GlcNHglycan	313	316	PF01048	0.421
MOD_GlcNHglycan	334	337	PF01048	0.457
MOD_GlcNHglycan	383	386	PF01048	0.323
MOD_GlcNHglycan	409	412	PF01048	0.291
MOD_GlcNHglycan	417	420	PF01048	0.324
MOD_GlcNHglycan	483	486	PF01048	0.355
MOD_GlcNHglycan	503	506	PF01048	0.318
MOD_GlcNHglycan	98	101	PF01048	0.383
MOD_GSK3_1	328	335	PF00069	0.410
MOD_GSK3_1	38	45	PF00069	0.485
MOD_GSK3_1	387	394	PF00069	0.294
MOD_GSK3_1	410	417	PF00069	0.299
MOD_GSK3_1	436	443	PF00069	0.350
MOD_N-GLC_1	364	369	PF02516	0.315
MOD_NEK2_1	149	154	PF00069	0.348
MOD_NEK2_1	267	272	PF00069	0.361
MOD_NEK2_1	330	335	PF00069	0.413
MOD_NEK2_1	369	374	PF00069	0.330
MOD_NEK2_1	415	420	PF00069	0.312
MOD_NEK2_1	425	430	PF00069	0.271
MOD_NEK2_1	449	454	PF00069	0.256
MOD_NEK2_1	481	486	PF00069	0.341
MOD_NEK2_1	70	75	PF00069	0.349
MOD_NEK2_2	142	147	PF00069	0.325
MOD_PKA_1	328	334	PF00069	0.405
MOD_PKA_1	49	55	PF00069	0.490
MOD_PKA_2	13	19	PF00069	0.382
MOD_PKA_2	226	232	PF00069	0.396
MOD_PKA_2	328	334	PF00069	0.405
MOD_PKA_2	369	375	PF00069	0.328
MOD_PKA_2	381	387	PF00069	0.319
MOD_PKA_2	481	487	PF00069	0.347
MOD_PKA_2	70	76	PF00069	0.348
MOD_Plk_1	122	128	PF00069	0.431
MOD_Plk_1	209	215	PF00069	0.370
MOD_Plk_1	287	293	PF00069	0.376
MOD_Plk_1	364	370	PF00069	0.324
MOD_Plk_2-3	296	302	PF00069	0.455
MOD_Plk_4	209	215	PF00069	0.370
MOD_ProDKin_1	186	192	PF00069	0.465
MOD_ProDKin_1	344	350	PF00069	0.465
MOD_ProDKin_1	42	48	PF00069	0.487
MOD_ProDKin_1	440	446	PF00069	0.347
MOD_ProDKin_1	59	65	PF00069	0.390
TRG_DiLeu_BaEn_4	318	324	PF01217	0.367
TRG_DiLeu_BaLyEn_6	105	110	PF01217	0.407
TRG_ENDOCYTIC_2	116	119	PF00928	0.416
TRG_ENDOCYTIC_2	143	146	PF00928	0.320
TRG_ENDOCYTIC_2	262	265	PF00928	0.343
TRG_ENDOCYTIC_2	465	468	PF00928	0.232
TRG_ER_diArg_1	103	106	PF00400	0.399
TRG_ER_diArg_1	248	250	PF00400	0.392
TRG_ER_diArg_1	274	277	PF00400	0.354
TRG_ER_diArg_1	327	329	PF00400	0.376
TRG_NES_CRM1_1	172	187	PF08389	0.380
TRG_NLS_MonoExtC_3	273	278	PF00514	0.357
TRG_NLS_MonoExtC_3	48	53	PF00514	0.495
TRG_NLS_MonoExtN_4	272	278	PF00514	0.361
TRG_NLS_MonoExtN_4	46	53	PF00514	0.493
TRG_Pf-PMV_PEXEL_1	168	172	PF00026	0.404
TRG_Pf-PMV_PEXEL_1	249	253	PF00026	0.394
TRG_Pf-PMV_PEXEL_1	479	483	PF00026	0.303