Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania infantum

UniProt:

A4I3A6_LEIIN

TriTrypDb:

LINF_280008200

Length:

457

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I3A6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I3A6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	162	166	PF00656	0.560
CLV_C14_Caspase3-7	285	289	PF00656	0.519
CLV_C14_Caspase3-7	378	382	PF00656	0.473
CLV_MEL_PAP_1	396	402	PF00089	0.473
CLV_NRD_NRD_1	205	207	PF00675	0.580
CLV_NRD_NRD_1	278	280	PF00675	0.588
CLV_NRD_NRD_1	342	344	PF00675	0.453
CLV_NRD_NRD_1	54	56	PF00675	0.413
CLV_PCSK_KEX2_1	205	207	PF00082	0.580
CLV_PCSK_KEX2_1	278	280	PF00082	0.566
CLV_PCSK_KEX2_1	342	344	PF00082	0.453
CLV_PCSK_KEX2_1	54	56	PF00082	0.413
CLV_PCSK_SKI1_1	237	241	PF00082	0.501
CLV_PCSK_SKI1_1	257	261	PF00082	0.462
CLV_PCSK_SKI1_1	278	282	PF00082	0.599
CLV_PCSK_SKI1_1	308	312	PF00082	0.503
CLV_PCSK_SKI1_1	73	77	PF00082	0.526
DEG_COP1_1	161	172	PF00400	0.568
DEG_SPOP_SBC_1	297	301	PF00917	0.518
DOC_CDC14_PxL_1	238	246	PF14671	0.441
DOC_CKS1_1	169	174	PF01111	0.580
DOC_CYCLIN_RxL_1	205	216	PF00134	0.643
DOC_CYCLIN_yCln2_LP_2	222	228	PF00134	0.525
DOC_CYCLIN_yCln2_LP_2	27	33	PF00134	0.422
DOC_CYCLIN_yCln2_LP_2	310	316	PF00134	0.477
DOC_MAPK_gen_1	137	144	PF00069	0.373
DOC_MAPK_gen_1	205	212	PF00069	0.578
DOC_MAPK_gen_1	284	292	PF00069	0.687
DOC_MAPK_MEF2A_6	257	265	PF00069	0.517
DOC_MAPK_MEF2A_6	404	411	PF00069	0.620
DOC_PP1_RVXF_1	235	241	PF00149	0.424
DOC_PP2B_LxvP_1	155	158	PF13499	0.496
DOC_PP2B_LxvP_1	239	242	PF13499	0.445
DOC_PP2B_LxvP_1	27	30	PF13499	0.445
DOC_USP7_MATH_1	17	21	PF00917	0.370
DOC_USP7_MATH_1	199	203	PF00917	0.593
DOC_USP7_MATH_1	297	301	PF00917	0.557
DOC_USP7_MATH_1	35	39	PF00917	0.432
DOC_USP7_MATH_1	392	396	PF00917	0.433
DOC_WW_Pin1_4	168	173	PF00397	0.569
DOC_WW_Pin1_4	197	202	PF00397	0.638
DOC_WW_Pin1_4	59	64	PF00397	0.492
LIG_14-3-3_CanoR_1	137	143	PF00244	0.386
LIG_14-3-3_CanoR_1	208	213	PF00244	0.632
LIG_14-3-3_CanoR_1	257	262	PF00244	0.494
LIG_14-3-3_CanoR_1	295	303	PF00244	0.597
LIG_14-3-3_CanoR_1	359	368	PF00244	0.595
LIG_14-3-3_CanoR_1	54	64	PF00244	0.465
LIG_14-3-3_CanoR_1	67	77	PF00244	0.422
LIG_Actin_WH2_2	38	56	PF00022	0.424
LIG_Actin_WH2_2	86	102	PF00022	0.399
LIG_APCC_ABBA_1	21	26	PF00400	0.571
LIG_APCC_ABBAyCdc20_2	223	229	PF00400	0.520
LIG_BIR_II_1	1	5	PF00653	0.548
LIG_deltaCOP1_diTrp_1	129	138	PF00928	0.356
LIG_EH1_1	232	240	PF00400	0.468
LIG_eIF4E_1	227	233	PF01652	0.500
LIG_FHA_1	100	106	PF00498	0.434
LIG_FHA_1	244	250	PF00498	0.597
LIG_FHA_1	251	257	PF00498	0.506
LIG_FHA_1	258	264	PF00498	0.473
LIG_FHA_1	348	354	PF00498	0.418
LIG_FHA_1	46	52	PF00498	0.385
LIG_FHA_2	105	111	PF00498	0.381
LIG_FHA_2	300	306	PF00498	0.555
LIG_FHA_2	332	338	PF00498	0.441
LIG_GBD_Chelix_1	435	443	PF00786	0.501
LIG_LIR_Gen_1	22	31	PF02991	0.386
LIG_LIR_Gen_1	348	358	PF02991	0.401
LIG_LIR_Gen_1	413	422	PF02991	0.541
LIG_LIR_Nem_3	151	155	PF02991	0.539
LIG_LIR_Nem_3	22	27	PF02991	0.349
LIG_LIR_Nem_3	231	236	PF02991	0.492
LIG_LIR_Nem_3	413	417	PF02991	0.686
LIG_SH2_STAP1	213	217	PF00017	0.566
LIG_SH2_STAP1	245	249	PF00017	0.646
LIG_SH2_STAP1	349	353	PF00017	0.421
LIG_SH2_STAP1	446	450	PF00017	0.526
LIG_SH2_STAT3	227	230	PF00017	0.494
LIG_SH2_STAT5	227	230	PF00017	0.659
LIG_SH2_STAT5	245	248	PF00017	0.440
LIG_SH2_STAT5	349	352	PF00017	0.427
LIG_SH2_STAT5	77	80	PF00017	0.482
LIG_SH3_3	166	172	PF00018	0.560
LIG_SH3_3	322	328	PF00018	0.475
LIG_Sin3_3	252	259	PF02671	0.477
LIG_SUMO_SIM_anti_2	288	294	PF11976	0.493
LIG_SUMO_SIM_anti_2	408	413	PF11976	0.500
LIG_SUMO_SIM_anti_2	48	53	PF11976	0.384
LIG_SUMO_SIM_par_1	101	107	PF11976	0.380
LIG_SUMO_SIM_par_1	208	214	PF11976	0.576
LIG_SUMO_SIM_par_1	43	50	PF11976	0.478
LIG_TRAF2_1	395	398	PF00917	0.456
LIG_Vh1_VBS_1	353	371	PF01044	0.482
LIG_WRC_WIRS_1	411	416	PF05994	0.479
MOD_CK1_1	161	167	PF00069	0.612
MOD_CK1_1	299	305	PF00069	0.528
MOD_CK1_1	329	335	PF00069	0.513
MOD_CK1_1	7	13	PF00069	0.444
MOD_CK2_1	299	305	PF00069	0.559
MOD_CK2_1	37	43	PF00069	0.473
MOD_CK2_1	391	397	PF00069	0.602
MOD_CK2_1	55	61	PF00069	0.353
MOD_GlcNHglycan	181	184	PF01048	0.754
MOD_GlcNHglycan	197	200	PF01048	0.519
MOD_GlcNHglycan	214	218	PF01048	0.469
MOD_GlcNHglycan	37	40	PF01048	0.473
MOD_GlcNHglycan	378	381	PF01048	0.463
MOD_GlcNHglycan	432	435	PF01048	0.504
MOD_GlcNHglycan	93	96	PF01048	0.575
MOD_GSK3_1	195	202	PF00069	0.542
MOD_GSK3_1	213	220	PF00069	0.528
MOD_GSK3_1	33	40	PF00069	0.456
MOD_GSK3_1	55	62	PF00069	0.464
MOD_LATS_1	324	330	PF00433	0.498
MOD_N-GLC_1	7	12	PF02516	0.595
MOD_NEK2_1	128	133	PF00069	0.539
MOD_NEK2_1	138	143	PF00069	0.307
MOD_NEK2_1	6	11	PF00069	0.637
MOD_NEK2_1	66	71	PF00069	0.522
MOD_NEK2_1	91	96	PF00069	0.643
MOD_PIKK_1	217	223	PF00454	0.673
MOD_PKA_2	138	144	PF00069	0.362
MOD_PKA_2	268	274	PF00069	0.616
MOD_PKA_2	283	289	PF00069	0.480
MOD_PKA_2	66	72	PF00069	0.528
MOD_PKB_1	206	214	PF00069	0.577
MOD_Plk_1	128	134	PF00069	0.353
MOD_Plk_1	347	353	PF00069	0.402
MOD_Plk_2-3	104	110	PF00069	0.382
MOD_Plk_2-3	405	411	PF00069	0.518
MOD_Plk_4	128	134	PF00069	0.357
MOD_Plk_4	19	25	PF00069	0.420
MOD_Plk_4	199	205	PF00069	0.599
MOD_Plk_4	208	214	PF00069	0.523
MOD_Plk_4	37	43	PF00069	0.444
MOD_Plk_4	47	53	PF00069	0.323
MOD_Plk_4	73	79	PF00069	0.549
MOD_ProDKin_1	168	174	PF00069	0.567
MOD_ProDKin_1	197	203	PF00069	0.639
MOD_ProDKin_1	59	65	PF00069	0.497
MOD_SUMO_for_1	360	363	PF00179	0.511
MOD_SUMO_rev_2	300	310	PF00179	0.490
TRG_DiLeu_BaEn_1	306	311	PF01217	0.499
TRG_DiLeu_BaLyEn_6	70	75	PF01217	0.480
TRG_ENDOCYTIC_2	314	317	PF00928	0.437
TRG_ER_diArg_1	144	147	PF00400	0.360
TRG_ER_diArg_1	186	189	PF00400	0.586
TRG_ER_diArg_1	204	206	PF00400	0.469
TRG_ER_diArg_1	277	279	PF00400	0.568
TRG_ER_diArg_1	342	344	PF00400	0.453
TRG_ER_diArg_1	53	55	PF00400	0.408
TRG_NES_CRM1_1	231	243	PF08389	0.446
TRG_Pf-PMV_PEXEL_1	279	283	PF00026	0.576
TRG_Pf-PMV_PEXEL_1	342	347	PF00026	0.443

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I4P0	Leptomonas seymouri	38%	99%
A0A3S7X184	Leishmania donovani	99%	100%