LeishMANIAdb
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Putative ribonuclease II-like protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative ribonuclease II-like protein
Gene product:
DIS3-like exonuclease - putative
Species:
Leishmania infantum
UniProt:
A4I3A3_LEIIN
TriTrypDb:
LINF_280007900
Length:
942

Annotations

Annotations by Jardim et al.

Nucleases, ribonuclease II-like

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0000178 exosome (RNase complex) 4 1
GO:0000932 P-body 5 1
GO:0005737 cytoplasm 2 1
GO:0032991 protein-containing complex 1 1
GO:0035770 ribonucleoprotein granule 3 1
GO:0036464 cytoplasmic ribonucleoprotein granule 4 1
GO:0043226 organelle 2 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0099080 supramolecular complex 2 1
GO:0110165 cellular anatomical entity 1 1
GO:1902494 catalytic complex 2 1
GO:1905354 exoribonuclease complex 3 1

Expansion

Sequence features

A4I3A3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I3A3

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006401 RNA catabolic process 5 1
GO:0006402 mRNA catabolic process 6 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0008152 metabolic process 1 1
GO:0009056 catabolic process 2 1
GO:0009057 macromolecule catabolic process 4 1
GO:0009892 negative regulation of metabolic process 4 1
GO:0009987 cellular process 1 1
GO:0010468 regulation of gene expression 5 1
GO:0010605 negative regulation of macromolecule metabolic process 5 1
GO:0010629 negative regulation of gene expression 6 1
GO:0016070 RNA metabolic process 5 1
GO:0016071 mRNA metabolic process 6 1
GO:0019222 regulation of metabolic process 3 1
GO:0019439 aromatic compound catabolic process 4 1
GO:0034641 cellular nitrogen compound metabolic process 3 1
GO:0034655 nucleobase-containing compound catabolic process 4 1
GO:0043170 macromolecule metabolic process 3 1
GO:0044237 cellular metabolic process 2 1
GO:0044238 primary metabolic process 2 1
GO:0044248 cellular catabolic process 3 1
GO:0044260 obsolete cellular macromolecule metabolic process 3 1
GO:0044265 obsolete cellular macromolecule catabolic process 4 1
GO:0044270 cellular nitrogen compound catabolic process 4 1
GO:0046483 heterocycle metabolic process 3 1
GO:0046700 heterocycle catabolic process 4 1
GO:0048519 negative regulation of biological process 3 1
GO:0050789 regulation of biological process 2 1
GO:0060255 regulation of macromolecule metabolic process 4 1
GO:0065007 biological regulation 1 1
GO:0071704 organic substance metabolic process 2 1
GO:0090304 nucleic acid metabolic process 4 1
GO:1901360 organic cyclic compound metabolic process 3 1
GO:1901361 organic cyclic compound catabolic process 4 1
GO:1901575 organic substance catabolic process 3 1
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 11
GO:0003723 RNA binding 4 11
GO:0003824 catalytic activity 1 11
GO:0004518 nuclease activity 4 11
GO:0004540 RNA nuclease activity 4 11
GO:0005488 binding 1 11
GO:0016787 hydrolase activity 2 11
GO:0016788 hydrolase activity, acting on ester bonds 3 11
GO:0097159 organic cyclic compound binding 2 11
GO:0140098 catalytic activity, acting on RNA 3 11
GO:0140640 catalytic activity, acting on a nucleic acid 2 11
GO:1901363 heterocyclic compound binding 2 11
GO:0000175 3'-5'-RNA exonuclease activity 7 1
GO:0004527 exonuclease activity 5 3
GO:0004532 RNA exonuclease activity 5 1
GO:0008408 3'-5' exonuclease activity 6 1
GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6 1
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 6 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 112 116 PF00656 0.441
CLV_C14_Caspase3-7 309 313 PF00656 0.427
CLV_C14_Caspase3-7 492 496 PF00656 0.564
CLV_NRD_NRD_1 307 309 PF00675 0.211
CLV_NRD_NRD_1 335 337 PF00675 0.306
CLV_NRD_NRD_1 366 368 PF00675 0.328
CLV_NRD_NRD_1 470 472 PF00675 0.302
CLV_NRD_NRD_1 559 561 PF00675 0.264
CLV_NRD_NRD_1 570 572 PF00675 0.226
CLV_NRD_NRD_1 651 653 PF00675 0.211
CLV_NRD_NRD_1 842 844 PF00675 0.702
CLV_NRD_NRD_1 853 855 PF00675 0.690
CLV_NRD_NRD_1 928 930 PF00675 0.471
CLV_PCSK_KEX2_1 157 159 PF00082 0.473
CLV_PCSK_KEX2_1 168 170 PF00082 0.393
CLV_PCSK_KEX2_1 18 20 PF00082 0.540
CLV_PCSK_KEX2_1 307 309 PF00082 0.215
CLV_PCSK_KEX2_1 366 368 PF00082 0.260
CLV_PCSK_KEX2_1 559 561 PF00082 0.272
CLV_PCSK_KEX2_1 570 572 PF00082 0.249
CLV_PCSK_KEX2_1 651 653 PF00082 0.211
CLV_PCSK_KEX2_1 754 756 PF00082 0.374
CLV_PCSK_KEX2_1 853 855 PF00082 0.662
CLV_PCSK_KEX2_1 928 930 PF00082 0.514
CLV_PCSK_PC1ET2_1 157 159 PF00082 0.473
CLV_PCSK_PC1ET2_1 168 170 PF00082 0.393
CLV_PCSK_PC1ET2_1 18 20 PF00082 0.368
CLV_PCSK_PC1ET2_1 754 756 PF00082 0.374
CLV_PCSK_PC7_1 924 930 PF00082 0.395
CLV_PCSK_SKI1_1 165 169 PF00082 0.485
CLV_PCSK_SKI1_1 18 22 PF00082 0.458
CLV_PCSK_SKI1_1 292 296 PF00082 0.517
CLV_PCSK_SKI1_1 357 361 PF00082 0.260
CLV_PCSK_SKI1_1 398 402 PF00082 0.211
CLV_PCSK_SKI1_1 472 476 PF00082 0.242
CLV_PCSK_SKI1_1 504 508 PF00082 0.277
CLV_PCSK_SKI1_1 573 577 PF00082 0.251
CLV_PCSK_SKI1_1 663 667 PF00082 0.218
CLV_PCSK_SKI1_1 710 714 PF00082 0.441
CLV_PCSK_SKI1_1 754 758 PF00082 0.406
DOC_ANK_TNKS_1 853 860 PF00023 0.700
DOC_CKS1_1 241 246 PF01111 0.528
DOC_CYCLIN_RxL_1 705 717 PF00134 0.352
DOC_CYCLIN_yCln2_LP_2 59 65 PF00134 0.383
DOC_CYCLIN_yCln2_LP_2 712 718 PF00134 0.233
DOC_MAPK_DCC_7 168 176 PF00069 0.337
DOC_MAPK_gen_1 168 176 PF00069 0.353
DOC_MAPK_gen_1 18 27 PF00069 0.372
DOC_MAPK_gen_1 44 54 PF00069 0.499
DOC_MAPK_gen_1 651 658 PF00069 0.424
DOC_MAPK_gen_1 660 668 PF00069 0.424
DOC_MAPK_gen_1 801 809 PF00069 0.484
DOC_MAPK_gen_1 908 918 PF00069 0.461
DOC_MAPK_MEF2A_6 168 176 PF00069 0.376
DOC_MAPK_MEF2A_6 660 668 PF00069 0.467
DOC_MAPK_MEF2A_6 908 916 PF00069 0.426
DOC_PP1_RVXF_1 502 508 PF00149 0.431
DOC_PP2B_LxvP_1 122 125 PF13499 0.494
DOC_PP4_FxxP_1 294 297 PF00568 0.350
DOC_PP4_FxxP_1 353 356 PF00568 0.467
DOC_PP4_FxxP_1 646 649 PF00568 0.411
DOC_USP7_MATH_1 137 141 PF00917 0.474
DOC_USP7_MATH_1 265 269 PF00917 0.451
DOC_USP7_MATH_1 348 352 PF00917 0.411
DOC_USP7_MATH_1 483 487 PF00917 0.371
DOC_USP7_MATH_1 63 67 PF00917 0.505
DOC_USP7_MATH_1 9 13 PF00917 0.535
DOC_USP7_MATH_1 90 94 PF00917 0.723
DOC_USP7_UBL2_3 844 848 PF12436 0.663
DOC_WW_Pin1_4 240 245 PF00397 0.528
DOC_WW_Pin1_4 295 300 PF00397 0.545
DOC_WW_Pin1_4 513 518 PF00397 0.548
DOC_WW_Pin1_4 645 650 PF00397 0.416
LIG_14-3-3_CanoR_1 366 374 PF00244 0.437
LIG_14-3-3_CanoR_1 384 392 PF00244 0.363
LIG_14-3-3_CanoR_1 489 494 PF00244 0.444
LIG_14-3-3_CanoR_1 573 582 PF00244 0.423
LIG_14-3-3_CanoR_1 869 874 PF00244 0.422
LIG_14-3-3_CanoR_1 911 915 PF00244 0.514
LIG_Actin_WH2_2 298 313 PF00022 0.482
LIG_Actin_WH2_2 481 496 PF00022 0.492
LIG_APCC_ABBA_1 893 898 PF00400 0.437
LIG_BRCT_BRCA1_1 401 405 PF00533 0.451
LIG_Clathr_ClatBox_1 404 408 PF01394 0.467
LIG_EH1_1 606 614 PF00400 0.506
LIG_EVH1_2 517 521 PF00568 0.506
LIG_FHA_1 126 132 PF00498 0.426
LIG_FHA_1 22 28 PF00498 0.500
LIG_FHA_1 241 247 PF00498 0.469
LIG_FHA_1 261 267 PF00498 0.287
LIG_FHA_1 369 375 PF00498 0.484
LIG_FHA_1 449 455 PF00498 0.475
LIG_FHA_1 645 651 PF00498 0.440
LIG_FHA_1 687 693 PF00498 0.591
LIG_FHA_1 697 703 PF00498 0.425
LIG_FHA_1 707 713 PF00498 0.320
LIG_FHA_1 767 773 PF00498 0.417
LIG_FHA_1 808 814 PF00498 0.657
LIG_FHA_1 895 901 PF00498 0.339
LIG_FHA_1 934 940 PF00498 0.553
LIG_FHA_2 110 116 PF00498 0.516
LIG_FHA_2 125 131 PF00498 0.341
LIG_FHA_2 321 327 PF00498 0.438
LIG_FHA_2 356 362 PF00498 0.506
LIG_FHA_2 606 612 PF00498 0.496
LIG_FHA_2 626 632 PF00498 0.323
LIG_FHA_2 820 826 PF00498 0.716
LIG_FHA_2 883 889 PF00498 0.461
LIG_FHA_2 95 101 PF00498 0.621
LIG_GBD_Chelix_1 664 672 PF00786 0.342
LIG_Integrin_RGD_1 603 605 PF01839 0.187
LIG_LIR_Apic_2 150 154 PF02991 0.429
LIG_LIR_Apic_2 293 297 PF02991 0.363
LIG_LIR_Apic_2 351 356 PF02991 0.415
LIG_LIR_Apic_2 644 649 PF02991 0.411
LIG_LIR_Gen_1 386 394 PF02991 0.412
LIG_LIR_Gen_1 534 544 PF02991 0.411
LIG_LIR_Gen_1 605 613 PF02991 0.445
LIG_LIR_Gen_1 792 802 PF02991 0.266
LIG_LIR_Gen_1 890 901 PF02991 0.367
LIG_LIR_Nem_3 192 198 PF02991 0.351
LIG_LIR_Nem_3 386 392 PF02991 0.412
LIG_LIR_Nem_3 534 539 PF02991 0.411
LIG_LIR_Nem_3 605 609 PF02991 0.452
LIG_LIR_Nem_3 711 716 PF02991 0.291
LIG_LIR_Nem_3 777 783 PF02991 0.348
LIG_LIR_Nem_3 792 798 PF02991 0.308
LIG_LIR_Nem_3 890 896 PF02991 0.450
LIG_LIR_Nem_3 897 902 PF02991 0.428
LIG_LYPXL_S_1 204 208 PF13949 0.361
LIG_LYPXL_SIV_4 438 446 PF13949 0.467
LIG_LYPXL_yS_3 205 208 PF13949 0.357
LIG_OCRL_FandH_1 794 806 PF00620 0.228
LIG_PCNA_yPIPBox_3 530 543 PF02747 0.421
LIG_Pex14_1 642 646 PF04695 0.424
LIG_Pex14_2 149 153 PF04695 0.327
LIG_Pex14_2 401 405 PF04695 0.411
LIG_Pex14_3 532 537 PF04695 0.424
LIG_PTB_Apo_2 276 283 PF02174 0.448
LIG_SH2_CRK 389 393 PF00017 0.424
LIG_SH2_CRK 554 558 PF00017 0.427
LIG_SH2_CRK 767 771 PF00017 0.502
LIG_SH2_CRK 804 808 PF00017 0.390
LIG_SH2_NCK_1 439 443 PF00017 0.411
LIG_SH2_NCK_1 767 771 PF00017 0.439
LIG_SH2_STAP1 615 619 PF00017 0.506
LIG_SH2_STAP1 743 747 PF00017 0.338
LIG_SH2_STAP1 783 787 PF00017 0.326
LIG_SH2_STAT5 372 375 PF00017 0.411
LIG_SH2_STAT5 389 392 PF00017 0.424
LIG_SH2_STAT5 551 554 PF00017 0.445
LIG_SH2_STAT5 622 625 PF00017 0.420
LIG_SH2_STAT5 643 646 PF00017 0.411
LIG_SH2_STAT5 653 656 PF00017 0.411
LIG_SH2_STAT5 748 751 PF00017 0.290
LIG_SH2_STAT5 767 770 PF00017 0.444
LIG_SH3_1 376 382 PF00018 0.442
LIG_SH3_1 560 566 PF00018 0.506
LIG_SH3_1 757 763 PF00018 0.468
LIG_SH3_1 929 935 PF00018 0.402
LIG_SH3_2 379 384 PF14604 0.429
LIG_SH3_2 563 568 PF14604 0.506
LIG_SH3_3 241 247 PF00018 0.509
LIG_SH3_3 376 382 PF00018 0.429
LIG_SH3_3 511 517 PF00018 0.470
LIG_SH3_3 560 566 PF00018 0.472
LIG_SH3_3 635 641 PF00018 0.506
LIG_SH3_3 677 683 PF00018 0.598
LIG_SH3_3 757 763 PF00018 0.438
LIG_SH3_3 929 935 PF00018 0.542
LIG_Sin3_3 70 77 PF02671 0.318
LIG_SUMO_SIM_anti_2 768 774 PF11976 0.415
LIG_SUMO_SIM_anti_2 897 904 PF11976 0.361
LIG_SUMO_SIM_par_1 312 320 PF11976 0.460
LIG_SUMO_SIM_par_1 449 455 PF11976 0.508
LIG_SUMO_SIM_par_1 901 906 PF11976 0.329
LIG_TRAF2_1 127 130 PF00917 0.502
LIG_TRAF2_1 587 590 PF00917 0.472
LIG_TRAF2_1 818 821 PF00917 0.687
LIG_TRAF2_1 885 888 PF00917 0.497
LIG_TYR_ITIM 552 557 PF00017 0.269
LIG_UBA3_1 481 487 PF00899 0.248
LIG_UBA3_1 594 600 PF00899 0.353
LIG_UBA3_1 749 757 PF00899 0.451
LIG_WRC_WIRS_1 254 259 PF05994 0.455
LIG_WRPW_2 198 201 PF00400 0.367
MOD_CDC14_SPxK_1 648 651 PF00782 0.247
MOD_CDK_SPK_2 240 245 PF00069 0.399
MOD_CDK_SPxK_1 645 651 PF00069 0.247
MOD_CDK_SPxxK_3 645 652 PF00069 0.247
MOD_CK1_1 226 232 PF00069 0.357
MOD_CK1_1 368 374 PF00069 0.446
MOD_CK1_1 383 389 PF00069 0.366
MOD_CK1_1 516 522 PF00069 0.316
MOD_CK1_1 878 884 PF00069 0.479
MOD_CK1_1 92 98 PF00069 0.674
MOD_CK2_1 124 130 PF00069 0.451
MOD_CK2_1 295 301 PF00069 0.503
MOD_CK2_1 584 590 PF00069 0.332
MOD_CK2_1 605 611 PF00069 0.349
MOD_CK2_1 714 720 PF00069 0.273
MOD_CK2_1 786 792 PF00069 0.430
MOD_CK2_1 878 884 PF00069 0.416
MOD_CK2_1 934 940 PF00069 0.524
MOD_CK2_1 94 100 PF00069 0.704
MOD_Cter_Amidation 305 308 PF01082 0.369
MOD_GlcNHglycan 135 138 PF01048 0.467
MOD_GlcNHglycan 401 404 PF01048 0.312
MOD_GlcNHglycan 55 58 PF01048 0.504
MOD_GlcNHglycan 586 589 PF01048 0.357
MOD_GlcNHglycan 716 719 PF01048 0.436
MOD_GlcNHglycan 734 737 PF01048 0.258
MOD_GlcNHglycan 783 786 PF01048 0.464
MOD_GlcNHglycan 816 819 PF01048 0.674
MOD_GlcNHglycan 86 89 PF01048 0.688
MOD_GlcNHglycan 866 869 PF01048 0.713
MOD_GSK3_1 133 140 PF00069 0.510
MOD_GSK3_1 222 229 PF00069 0.445
MOD_GSK3_1 271 278 PF00069 0.479
MOD_GSK3_1 38 45 PF00069 0.482
MOD_GSK3_1 412 419 PF00069 0.398
MOD_GSK3_1 426 433 PF00069 0.390
MOD_GSK3_1 513 520 PF00069 0.454
MOD_GSK3_1 580 587 PF00069 0.284
MOD_GSK3_1 641 648 PF00069 0.250
MOD_GSK3_1 737 744 PF00069 0.484
MOD_GSK3_1 819 826 PF00069 0.711
MOD_GSK3_1 878 885 PF00069 0.520
MOD_GSK3_1 90 97 PF00069 0.721
MOD_N-GLC_1 133 138 PF02516 0.509
MOD_N-GLC_1 221 226 PF02516 0.454
MOD_N-GLC_1 275 280 PF02516 0.359
MOD_N-GLC_1 368 373 PF02516 0.379
MOD_N-GLC_1 38 43 PF02516 0.384
MOD_N-GLC_2 727 729 PF02516 0.456
MOD_NEK2_1 399 404 PF00069 0.247
MOD_NEK2_1 42 47 PF00069 0.449
MOD_NEK2_1 426 431 PF00069 0.247
MOD_NEK2_1 594 599 PF00069 0.205
MOD_NEK2_1 613 618 PF00069 0.307
MOD_NEK2_1 741 746 PF00069 0.444
MOD_NEK2_1 766 771 PF00069 0.483
MOD_NEK2_1 903 908 PF00069 0.496
MOD_PKA_2 310 316 PF00069 0.450
MOD_PKA_2 365 371 PF00069 0.394
MOD_PKA_2 383 389 PF00069 0.425
MOD_PKA_2 43 49 PF00069 0.474
MOD_PKA_2 831 837 PF00069 0.695
MOD_PKA_2 910 916 PF00069 0.525
MOD_Plk_1 137 143 PF00069 0.452
MOD_Plk_1 259 265 PF00069 0.529
MOD_Plk_1 292 298 PF00069 0.557
MOD_Plk_1 348 354 PF00069 0.247
MOD_Plk_1 368 374 PF00069 0.379
MOD_Plk_1 38 44 PF00069 0.397
MOD_Plk_1 448 454 PF00069 0.243
MOD_Plk_1 737 743 PF00069 0.314
MOD_Plk_2-3 280 286 PF00069 0.420
MOD_Plk_2-3 605 611 PF00069 0.314
MOD_Plk_2-3 786 792 PF00069 0.430
MOD_Plk_2-3 94 100 PF00069 0.587
MOD_Plk_4 21 27 PF00069 0.444
MOD_Plk_4 223 229 PF00069 0.363
MOD_Plk_4 253 259 PF00069 0.390
MOD_Plk_4 368 374 PF00069 0.294
MOD_Plk_4 38 44 PF00069 0.461
MOD_Plk_4 426 432 PF00069 0.247
MOD_Plk_4 448 454 PF00069 0.271
MOD_Plk_4 517 523 PF00069 0.269
MOD_Plk_4 613 619 PF00069 0.379
MOD_Plk_4 768 774 PF00069 0.361
MOD_Plk_4 776 782 PF00069 0.406
MOD_Plk_4 786 792 PF00069 0.468
MOD_Plk_4 934 940 PF00069 0.520
MOD_ProDKin_1 240 246 PF00069 0.522
MOD_ProDKin_1 295 301 PF00069 0.548
MOD_ProDKin_1 513 519 PF00069 0.438
MOD_ProDKin_1 645 651 PF00069 0.253
MOD_SUMO_rev_2 391 400 PF00179 0.332
MOD_SUMO_rev_2 812 818 PF00179 0.664
MOD_SUMO_rev_2 831 838 PF00179 0.501
TRG_AP2beta_CARGO_1 534 543 PF09066 0.247
TRG_DiLeu_BaEn_1 534 539 PF01217 0.269
TRG_DiLeu_BaEn_1 777 782 PF01217 0.443
TRG_DiLeu_BaEn_1 898 903 PF01217 0.395
TRG_DiLeu_BaEn_4 387 393 PF01217 0.360
TRG_DiLeu_BaEn_4 534 540 PF01217 0.290
TRG_ENDOCYTIC_2 195 198 PF00928 0.354
TRG_ENDOCYTIC_2 205 208 PF00928 0.333
TRG_ENDOCYTIC_2 389 392 PF00928 0.265
TRG_ENDOCYTIC_2 554 557 PF00928 0.269
TRG_ENDOCYTIC_2 615 618 PF00928 0.300
TRG_ENDOCYTIC_2 643 646 PF00928 0.247
TRG_ENDOCYTIC_2 653 656 PF00928 0.247
TRG_ENDOCYTIC_2 767 770 PF00928 0.507
TRG_ENDOCYTIC_2 804 807 PF00928 0.411
TRG_ER_diArg_1 431 434 PF00400 0.265
TRG_ER_diArg_1 558 560 PF00400 0.366
TRG_ER_diArg_1 569 571 PF00400 0.379
TRG_ER_diArg_1 650 652 PF00400 0.247
TRG_ER_diArg_1 852 854 PF00400 0.758
TRG_ER_diArg_1 928 930 PF00400 0.419
TRG_NES_CRM1_1 764 777 PF08389 0.343
TRG_NES_CRM1_1 894 909 PF08389 0.385
TRG_NLS_MonoExtC_3 470 475 PF00514 0.247
TRG_NLS_MonoExtN_4 471 476 PF00514 0.247
TRG_Pf-PMV_PEXEL_1 117 121 PF00026 0.445
TRG_Pf-PMV_PEXEL_1 308 312 PF00026 0.247
TRG_Pf-PMV_PEXEL_1 325 329 PF00026 0.247

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IJ70 Leptomonas seymouri 61% 99%
A0A0S4KIX9 Bodo saltans 36% 100%
A0A1X0NYL5 Trypanosomatidae 41% 97%
A0A3Q8IHX8 Leishmania donovani 100% 100%
A0A3R7NDR6 Trypanosoma rangeli 30% 98%
A0A422P1Q3 Trypanosoma rangeli 40% 100%
A0JN80 Bos taurus 27% 89%
A2RV18 Danio rerio 27% 89%
A4HG84 Leishmania braziliensis 81% 99%
D0A7T6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 97%
D0A826 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 38% 100%
E9AZK5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
O14040 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 31% 100%
P0DM58 Arabidopsis thaliana 32% 89%
Q0P4R5 Xenopus tropicalis 28% 91%
Q0V9R3 Xenopus tropicalis 31% 100%
Q0WPN0 Arabidopsis thaliana 31% 89%
Q4Q8M6 Leishmania major 95% 100%
Q5R5N8 Pongo abelii 28% 89%
Q5U2P0 Rattus norvegicus 28% 89%
Q8C0S1 Mus musculus 27% 89%
Q8CI75 Mus musculus 31% 100%
Q8TF46 Homo sapiens 27% 89%
Q9CSH3 Mus musculus 28% 98%
Q9SHL7 Arabidopsis thaliana 28% 100%
Q9Y2L1 Homo sapiens 27% 98%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS