LeishMANIAdb
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Putative propionyl-coa carboxylase beta chain

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative propionyl-coa carboxylase beta chain
Gene product:
propionyl-coa carboxylase beta chain - putative
Species:
Leishmania infantum
UniProt:
A4I399_LEIIN
TriTrypDb:
LINF_280007400
Length:
165

Annotations

Annotations by Jardim et al.

Fatty acid metabolism, propionyl-coa carboxylase beta chain

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I399
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I399

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 2
GO:0004658 propionyl-CoA carboxylase activity 5 2
GO:0016421 CoA carboxylase activity 4 2
GO:0016874 ligase activity 2 2
GO:0016885 ligase activity, forming carbon-carbon bonds 3 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 123 125 PF00675 0.199
CLV_NRD_NRD_1 149 151 PF00675 0.199
CLV_NRD_NRD_1 55 57 PF00675 0.199
DOC_CKS1_1 116 121 PF01111 0.199
DOC_MAPK_gen_1 158 165 PF00069 0.199
DOC_PP4_FxxP_1 116 119 PF00568 0.199
DOC_PP4_FxxP_1 8 11 PF00568 0.199
DOC_WW_Pin1_4 115 120 PF00397 0.199
LIG_AP2alpha_1 4 8 PF02296 0.199
LIG_FHA_2 12 18 PF00498 0.199
LIG_Integrin_RGD_1 72 74 PF01839 0.199
LIG_LIR_Apic_2 113 119 PF02991 0.199
LIG_LIR_Apic_2 6 11 PF02991 0.199
LIG_LIR_Apic_2 74 80 PF02991 0.199
LIG_LIR_Gen_1 14 23 PF02991 0.199
LIG_LIR_Nem_3 14 18 PF02991 0.199
LIG_LIR_Nem_3 28 32 PF02991 0.199
LIG_PCNA_yPIPBox_3 3 16 PF02747 0.199
LIG_PDZ_Class_2 160 165 PF00595 0.199
LIG_Pex14_2 4 8 PF04695 0.199
LIG_SH2_CRK 29 33 PF00017 0.199
LIG_SH2_NCK_1 112 116 PF00017 0.199
LIG_SH2_NCK_1 43 47 PF00017 0.199
LIG_SH2_SRC 41 44 PF00017 0.199
LIG_SH2_STAP1 112 116 PF00017 0.199
LIG_SH3_3 128 134 PF00018 0.199
LIG_SH3_3 13 19 PF00018 0.199
LIG_SUMO_SIM_anti_2 83 88 PF11976 0.199
LIG_WRC_WIRS_1 12 17 PF05994 0.199
MOD_CK1_1 98 104 PF00069 0.199
MOD_GlcNHglycan 120 123 PF01048 0.199
MOD_LATS_1 70 76 PF00433 0.199
MOD_PKA_2 146 152 PF00069 0.199
MOD_Plk_1 44 50 PF00069 0.199
MOD_Plk_4 49 55 PF00069 0.199
MOD_ProDKin_1 115 121 PF00069 0.199
TRG_ENDOCYTIC_2 29 32 PF00928 0.199
TRG_ENDOCYTIC_2 63 66 PF00928 0.199
TRG_ER_diArg_1 138 141 PF00400 0.199

Homologs

Protein Taxonomy Sequence identity Coverage
A4SX64 POLAQ 31% 51%
B1XUY6 POLNS 29% 51%
I3R7F1 HALMT 61% 32%
I6YDK7 MYCTU 30% 31%
O31825 BACSU 35% 32%
O53578 MYCTU 51% 32%
O54028 PROMO 57% 32%
O86318 MYCTU 26% 31%
P05166 HUMAN 68% 31%
P07633 RAT 67% 30%
P53002 MYCLE 57% 30%
P53003 SACEN 60% 30%
P54541 BACSU 56% 33%
P63408 MYCBO 47% 35%
P79384 PIG 67% 31%
P9WQH4 MYCTO 47% 35%
P9WQH5 MYCTU 47% 35%
P9WQH6 MYCTO 57% 30%
P9WQH7 MYCTU 57% 30%
Q06101 RHOER 53% 35%
Q168G2 ROSDO 62% 32%
Q2TBR0 BOVIN 67% 31%
Q39WC1 GEOMG 28% 52%
Q3J4E3 CERS4 66% 32%
Q47HT1 DECAR 30% 51%
Q57079 VEIPA 59% 32%
Q5P2J0 AROAE 30% 51%
Q74DB5 GEOSL 33% 52%
Q7VX94 BORPE 28% 51%
Q7W860 BORPA 28% 51%
Q7WLK8 BORBR 28% 51%
Q8GBW6 PROFR 56% 31%
Q99MN9 MOUSE 68% 30%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS