LeishMANIAdb
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EF-hand domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
EF-hand domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4I396_LEIIN
TriTrypDb:
LINF_280007200
Length:
328

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I396
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I396

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 250 252 PF00675 0.754
CLV_PCSK_KEX2_1 249 251 PF00082 0.757
CLV_PCSK_KEX2_1 301 303 PF00082 0.610
CLV_PCSK_PC1ET2_1 301 303 PF00082 0.610
CLV_Separin_Metazoa 246 250 PF03568 0.580
DOC_CKS1_1 15 20 PF01111 0.778
DOC_USP7_MATH_1 174 178 PF00917 0.666
DOC_USP7_MATH_1 199 203 PF00917 0.720
DOC_USP7_MATH_1 97 101 PF00917 0.828
DOC_WW_Pin1_4 100 105 PF00397 0.742
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IHW6 Leishmania donovani 99% 100%
A4HG64 Leishmania braziliensis 55% 100%
E9AZI4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%
Q4Q8P7 Leishmania major 88% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS