Aminotran_5 domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I393_LEIIN

TriTrypDb:

LINF_280006900

Length:

333

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I393

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I393

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	224	226	PF00675	0.235
CLV_NRD_NRD_1	307	309	PF00675	0.288
CLV_NRD_NRD_1	99	101	PF00675	0.228
CLV_PCSK_KEX2_1	224	226	PF00082	0.235
CLV_PCSK_KEX2_1	267	269	PF00082	0.228
CLV_PCSK_PC1ET2_1	267	269	PF00082	0.228
DEG_Nend_UBRbox_1	1	4	PF02207	0.225
DEG_SPOP_SBC_1	76	80	PF00917	0.194
DOC_CKS1_1	282	287	PF01111	0.243
DOC_CYCLIN_yCln2_LP_2	185	191	PF00134	0.240
DOC_MAPK_gen_1	224	235	PF00069	0.215
DOC_MAPK_gen_1	95	104	PF00069	0.226
DOC_PP2B_LxvP_1	185	188	PF13499	0.246
DOC_PP4_FxxP_1	137	140	PF00568	0.223
DOC_USP7_MATH_1	220	224	PF00917	0.235
DOC_USP7_MATH_1	231	235	PF00917	0.205
DOC_WW_Pin1_4	136	141	PF00397	0.229
DOC_WW_Pin1_4	281	286	PF00397	0.242
DOC_WW_Pin1_4	302	307	PF00397	0.262
LIG_14-3-3_CanoR_1	276	282	PF00244	0.213
LIG_Actin_WH2_2	262	278	PF00022	0.217
LIG_BRCT_BRCA1_1	141	145	PF00533	0.249
LIG_FHA_1	13	19	PF00498	0.212
LIG_FHA_1	55	61	PF00498	0.224
LIG_FHA_1	67	73	PF00498	0.205
LIG_FHA_1	77	83	PF00498	0.192
LIG_FHA_1	86	92	PF00498	0.202
LIG_FHA_2	282	288	PF00498	0.235
LIG_LIR_Gen_1	14	24	PF02991	0.220
LIG_LIR_Gen_1	183	191	PF02991	0.235
LIG_LIR_Gen_1	286	296	PF02991	0.223
LIG_LIR_Nem_3	114	120	PF02991	0.271
LIG_LIR_Nem_3	14	20	PF02991	0.215
LIG_LIR_Nem_3	142	148	PF02991	0.233
LIG_LIR_Nem_3	178	184	PF02991	0.251
LIG_LIR_Nem_3	286	291	PF02991	0.229
LIG_REV1ctd_RIR_1	143	153	PF16727	0.236
LIG_SH2_NCK_1	282	286	PF00017	0.243
LIG_SH2_PTP2	288	291	PF00017	0.217
LIG_SH2_STAP1	312	316	PF00017	0.311
LIG_SH2_STAT5	17	20	PF00017	0.231
LIG_SH2_STAT5	184	187	PF00017	0.238
LIG_SH2_STAT5	205	208	PF00017	0.241
LIG_SH2_STAT5	251	254	PF00017	0.231
LIG_SH2_STAT5	274	277	PF00017	0.189
LIG_SH2_STAT5	288	291	PF00017	0.217
LIG_SH2_STAT5	75	78	PF00017	0.189
LIG_SH3_3	233	239	PF00018	0.198
LIG_SH3_3	259	265	PF00018	0.243
LIG_SH3_3	300	306	PF00018	0.258
LIG_SUMO_SIM_par_1	234	240	PF11976	0.208
LIG_SUMO_SIM_par_1	293	300	PF11976	0.219
LIG_SUMO_SIM_par_1	69	74	PF11976	0.192
LIG_TYR_ITSM	13	20	PF00017	0.210
MOD_CDC14_SPxK_1	305	308	PF00782	0.270
MOD_CDK_SPK_2	136	141	PF00069	0.229
MOD_CDK_SPxK_1	302	308	PF00069	0.262
MOD_CDK_SPxxK_3	302	309	PF00069	0.268
MOD_CK1_1	124	130	PF00069	0.213
MOD_CK1_1	139	145	PF00069	0.241
MOD_CK1_1	245	251	PF00069	0.249
MOD_CK2_1	231	237	PF00069	0.203
MOD_CK2_1	281	287	PF00069	0.243
MOD_CK2_1	31	37	PF00069	0.228
MOD_GlcNHglycan	141	144	PF01048	0.252
MOD_GlcNHglycan	211	214	PF01048	0.212
MOD_GlcNHglycan	277	280	PF01048	0.195
MOD_GlcNHglycan	79	82	PF01048	0.191
MOD_GSK3_1	135	142	PF00069	0.237
MOD_GSK3_1	155	162	PF00069	0.264
MOD_GSK3_1	204	211	PF00069	0.231
MOD_N-GLC_1	66	71	PF02516	0.223
MOD_NEK2_1	209	214	PF00069	0.207
MOD_NEK2_1	242	247	PF00069	0.223
MOD_NEK2_1	275	280	PF00069	0.195
MOD_PIKK_1	121	127	PF00454	0.233
MOD_PK_1	155	161	PF00069	0.267
MOD_PKA_2	275	281	PF00069	0.201
MOD_PKA_2	314	320	PF00069	0.321
MOD_Plk_1	51	57	PF00069	0.244
MOD_Plk_1	66	72	PF00069	0.217
MOD_Plk_4	124	130	PF00069	0.213
MOD_Plk_4	155	161	PF00069	0.267
MOD_Plk_4	180	186	PF00069	0.244
MOD_Plk_4	231	237	PF00069	0.203
MOD_Plk_4	242	248	PF00069	0.229
MOD_Plk_4	67	73	PF00069	0.205
MOD_ProDKin_1	136	142	PF00069	0.236
MOD_ProDKin_1	281	287	PF00069	0.243
MOD_ProDKin_1	302	308	PF00069	0.262
MOD_SUMO_rev_2	114	120	PF00179	0.271
TRG_ENDOCYTIC_2	17	20	PF00928	0.231
TRG_ENDOCYTIC_2	184	187	PF00928	0.238
TRG_ENDOCYTIC_2	21	24	PF00928	0.229
TRG_ENDOCYTIC_2	274	277	PF00928	0.189
TRG_ENDOCYTIC_2	288	291	PF00928	0.217
TRG_ER_diArg_1	224	226	PF00400	0.235
TRG_ER_diArg_1	94	97	PF00400	0.231
TRG_Pf-PMV_PEXEL_1	42	46	PF00026	0.224

Homologs


Protein	Taxonomy	Sequence identity	Coverage
P18549	Streptomyces clavuligerus	25%	84%
Q03046	Amycolatopsis lactamdurans	29%	84%
Q3E6S9	Arabidopsis thaliana	28%	70%
Q5JNT6	Oryza sativa subsp. japonica	27%	70%
Q9LGZ2	Oryza sativa subsp. japonica	27%	69%
Q9M1R1	Arabidopsis thaliana	29%	73%