Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4I362_LEIIN

TriTrypDb:

LINF_270006300

Length:

217

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4I362

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4I362

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	135	137	PF00675	0.684
CLV_NRD_NRD_1	74	76	PF00675	0.661
CLV_PCSK_KEX2_1	107	109	PF00082	0.700
CLV_PCSK_PC1ET2_1	107	109	PF00082	0.700
CLV_PCSK_SKI1_1	144	148	PF00082	0.761
CLV_PCSK_SKI1_1	182	186	PF00082	0.735
CLV_PCSK_SKI1_1	88	92	PF00082	0.697
DEG_Nend_Nbox_1	1	3	PF02207	0.523
DOC_CKS1_1	147	152	PF01111	0.678
DOC_USP7_MATH_1	129	133	PF00917	0.638
DOC_USP7_MATH_1	22	26	PF00917	0.663
DOC_USP7_MATH_1	54	58	PF00917	0.667
DOC_USP7_MATH_1	81	85	PF00917	0.526
DOC_WW_Pin1_4	12	17	PF00397	0.733
DOC_WW_Pin1_4	121	126	PF00397	0.662
DOC_WW_Pin1_4	146	151	PF00397	0.679
LIG_14-3-3_CanoR_1	108	112	PF00244	0.751
LIG_14-3-3_CanoR_1	186	194	PF00244	0.669
LIG_14-3-3_CanoR_1	58	64	PF00244	0.581
LIG_BIR_III_4	114	118	PF00653	0.729
LIG_deltaCOP1_diTrp_1	159	165	PF00928	0.647
LIG_FHA_1	107	113	PF00498	0.702
LIG_FHA_2	154	160	PF00498	0.732
LIG_FHA_2	87	93	PF00498	0.635
LIG_LIR_Nem_3	84	90	PF02991	0.745
LIG_Pex14_1	161	165	PF04695	0.649
LIG_SH2_CRK	87	91	PF00017	0.689
LIG_SH2_STAT5	200	203	PF00017	0.610
LIG_SH2_STAT5	214	217	PF00017	0.633
LIG_SH2_STAT5	79	82	PF00017	0.673
LIG_SH3_2	152	157	PF14604	0.609
LIG_SH3_3	149	155	PF00018	0.577
LIG_WRC_WIRS_1	162	167	PF05994	0.732
MOD_CDK_SPK_2	146	151	PF00069	0.679
MOD_CK1_1	25	31	PF00069	0.520
MOD_CK1_1	7	13	PF00069	0.548
MOD_CK2_1	153	159	PF00069	0.731
MOD_GlcNHglycan	11	14	PF01048	0.715
MOD_GlcNHglycan	114	118	PF01048	0.605
MOD_GlcNHglycan	24	27	PF01048	0.527
MOD_GSK3_1	161	168	PF00069	0.732
MOD_GSK3_1	178	185	PF00069	0.469
MOD_GSK3_1	59	66	PF00069	0.593
MOD_GSK3_1	77	84	PF00069	0.697
MOD_N-GLC_1	127	132	PF02516	0.608
MOD_NEK2_1	106	111	PF00069	0.702
MOD_NEK2_1	165	170	PF00069	0.675
MOD_PKA_1	107	113	PF00069	0.672
MOD_PKA_2	107	113	PF00069	0.662
MOD_PKA_2	178	184	PF00069	0.625
MOD_PKA_2	207	213	PF00069	0.628
MOD_PKA_2	54	60	PF00069	0.687
MOD_PKA_2	70	76	PF00069	0.493
MOD_Plk_1	47	53	PF00069	0.656
MOD_Plk_4	107	113	PF00069	0.691
MOD_Plk_4	115	121	PF00069	0.596
MOD_Plk_4	25	31	PF00069	0.582
MOD_ProDKin_1	12	18	PF00069	0.735
MOD_ProDKin_1	121	127	PF00069	0.665
MOD_ProDKin_1	146	152	PF00069	0.676
TRG_ENDOCYTIC_2	87	90	PF00928	0.618

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJK2	Leptomonas seymouri	40%	90%
A0A3Q8ID42	Leishmania donovani	99%	100%
E9ACZ1	Leishmania major	94%	100%
E9AIS4	Leishmania braziliensis	71%	100%
E9AYR6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%